HiPhenolic Review: Can Polyphenols Reduce BP?

HiPhenolic Review: Can Polyphenols Reduce BP?

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Disclaimer: None of the information in this article constitutes medical advice, and is just the opinion of the writer(s). We recommend that patients follow their doctor’s guidance in regard to blood pressure support.

HiPhenolic is a dietary supplement from a brand called Ortho Molecular Products that's used for blood pressure support. The brand describes this supplement as a "highly purified polyphenolic blend" that provides "support to maintain normal blood pressure levels."

But does HiPhenolic contain research-backed ingredients for blood pressure support? Does the brand contain any questionable additives? How do real users rate and describe its effects? And can exercise reduce blood pressure?

In this article we'll answer all of these questions and more, as we analyze the ingredients in HiPhenolic to give our take on whether or not it's likely to be effective for blood pressure support. 

We'll feature customer reviews of the supplement, and share a video on some exercises that may reduce blood pressure.

Ingredient Analysis

HiPhenolic active ingredients

The active ingredients in HiPhenolic are shown above.

Magnesium is a mineral that's clinically shown to reduce blood pressure in hypertensive patients, but we can't find any studies showing it does so at the relatively low dose in this supplement of 50 milligrams (mg).

Lemon verbena leaf extract and hibiscus flower extract were shown to reduce blood pressure in a medical review published in the Foods journal.

The study authors also noted "potential weight loss benefits" when hibiscus was combined with other plant extracts, which suggests that this supplement may be particularly beneficial in patients who are overweight and have high blood pressure.

Green coffee bean extract was shown to reduce blood pressure by 13.76/6.56 mmHg in patients with metabolic syndrome, in a 2018 clinical trial.

This ingredient is also clinically shown to support up to 10 pounds of weight loss when used at a similar dose as that in HiPhenolic, as we documented in our Plexus review article.

Overall, we consider HiPhenolic to be effectively formulated, and we consider this supplement likely to support healthy blood pressure levels.

Our main concern is that the brand fails to publish the inactive ingredients (if any exist) on their Supplement Facts panel.

Oral supplements are typically composed of active ingredients (like those discussed above) and inactive ingredients (like capsule material, filler material, stabilizers, etc).

Given that this is a capsule supplement, we expect there to be inactive ingredients, and we urge the brand to publish this information clearly.

Failure to do so is a consumer safety issue, because consumers can have sensitivities or allergies to inactive ingredients.

What's the Best Exercise for BP?

A doctor and YouTube creator named Jeffrey Peng has a video with his opinion on the single best exercise for BP reduction:

Doctor Reviews HiPhenolic

A TikTok creator named "suesacharmd" suggests that HiPhenolic is effective for weight loss:

@susacharmd #weightloss #natural #energy #fitness #goals #tgif #fatloss #results #susacharmd ♬ original sound - Su Sachar MD

Our Clean BP Support Picks

There are some supplements with significant research backing for blood pressure support.

Coenzyme Q10 (CoQ10) was shown in a meta-study published in the Journal of Human Hypertension to "to lower systolic blood pressure by up to 17 mm Hg and diastolic blood pressure by up to 10 mm Hg without significant side effects."

Bulletproof CoQ10 is our top CoQ10 supplement pick because it provides an effective CoQ10 dose (100 mg). 

Magnesium is a mineral that "may reduce blood pressure (BP) as much as 5.6/2.8 mm Hg" when dosed between 500 mg per day and 1,000 mg per day according to a medical review published in The Journal of Clinical Hypertension.

Bulletproof Magnesium is our top magnesium supplement.

Both of the products recommended in this section are entirely free of ingredients that we consider to be unhealthy.

We are not recommending the use of these supplements to treat any specific medical condition, rather sharing clinical research that may benefit some consumers. We recommend speaking with a doctor prior to taking any new supplement.

Pros and Cons of HiPhenolic

Here are the pros and cons of HiPhenolic in our opinion:


  • Effective formulation
  • Active ingredients should be safe
  • Should support healthy BP levels
  • Some positive online reviews


  • No clear inactive ingredient list
  • Doesn't appear clinically tested
  • Challenging to find customer reviews
  • Brand website requires login to purchase
Stay up-to-date on our research reviews


HiPhenolic is a better-than-average BP support supplement based on its active ingredients and their respective doses.

All of the active ingredients in this formulation have research backing for BP support, and we consider all of them except for magnesium to be effectively dosed.

We don't currently recommend this supplement because we're unable to identify the inactive ingredients, which the brand fails to publish on their Supplement Facts panel on their website.

If it contains no inactive ingredients, the brand should clarify that, but that would be highly unusual for a capsule formulation.

It's quite challenging to find customer reviews of this supplement, perhaps because its manufacturer is relatively unknown.

In this article we featured a video from a doctor on the best exercise for BP support, which may be a useful resource for readers with high BP.