Ovasitol Review: Can Supplements Treat PCOS?

Ovasitol Review: Can Supplements Treat PCOS?


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Disclaimer: None of the information in this article constitutes medical advice, and is just the opinion of the writer(s). We recommend that patients follow their doctor’s guidance in regard to dietary supplements.

Ovasitol is a women's health supplement manufactured by a company called Theralogix. The brand claims that their supplement can promote healthy hormone levels, and support regular menstrual cycles and fertility.

But does Ovasitol contain research-backed ingredients for promoting healthy menstrual cycles and hormone levels, or are these just marketing claims? Does the supplement contain any questionable additive ingredients? Will it cause side effects? And how do real users rate and describe the effects of Ovasitol?

In this article we'll answer all of these questions and more as we analyze the ingredients in Ovasitol based on medical studies to give our take on whether the supplement is likely to be effective, or if it's a waste of money.

We'll discuss the potential for side effects, share our opinion on whether the supplement may cause weight loss, and feature unsponsored Ovasitol customer reviews.

We'll also provide a cost breakdown to show which retailer sells Ovasitol for the best price.

Ingredient Analysis

Ovasitol ingredients

Ovasitol contains two ingredients: myo-inositol and d-chiro-inositol

These are both forms of inositol, which is a compound produced naturally by the body that affects insulin function and hormones.

The dosage instructions provided by Ovasitol recommend a twice-daily use of the supplement, resulting in a 4 gram (g) daily dose of myo-inositol and a 100 milligram (mg) daily dose of d-chiro-inositol.

This combination of active ingredients has been shown to support women's health in research studies.

A 2019 clinical trial reported that the two forms of inositol at the exact same ratio as in Ovasitol (40:1) restored ovulation in five out of eight women with polycystic ovary syndrome (PCOS), and increased progesterone levels by nearly 50x.

A 2022 clinical trial found that myo-inositol and d-chiro-inositol improved menstrual regularity in women with PCOS. Average menstrual cycle length decreased from 124.5 days to 57.8 days, and insulin resistance improved.

84% of women on inositol regained periods compared to 100% of women on oral contraceptives.

A clinical trial published in the European Review for Medical and Pharmacological Sciences evaluated the effects of myo-inositol in insulin-resistant women.

The researchers found that myo-inositol had “significantly beneficial” effects on progesterone levels (a sign of fertility) and on pregnancy rates. The group taking myo-inositol were also taking 400 micrograms (mcg) of folic acid, so we can’t attribute these results to inositol alone.

There are no inactive ingredients at all in Ovasitol, which is good for consumers because many supplements contain inactive ingredients like refined sugar and artificial flavors that we consider to be unhealthy.

Overall, we consider Ovasitol likely to support healthy hormonal function and fertility in women with PCOS, and we recommend this supplement from a formulation perspective.

Women with PCOS may benefit from speaking with their doctor about Ovasitol prior to trying more invasive or risky treatments.

We haven't come across much convincing medical evidence that the two ingredients in Ovasitol are beneficial for women without PCOS.

But does the supplement cause side effects? We'll answer that question in the next section.

Does Ovasitol Cause Side Effects?

Ovasitol claims that their supplement is unlikely to cause any side effects. In an FAQ section on their site, the brand states the following: “There are no expected side effects from Ovasitol.”

Medical research suggests that this claim is accurate.

A 2011 meta-study on inositol found that only the highest dose of inositol (which was 12 g per day, or 3x the amount in Ovasitol) caused side effects, and even then the side effects were minor such as nausea and gas.

Even in women with PCOS, there don't appear to be any side effects.

A medical study published in the International Journal of Endocrinology found that 4,000 mg of myo-inositol (the exact dose and type in Ovasitol) caused no side effects compared to a placebo group:

“No relevant side effects were present among the patients.”

Overall, we do not expect Ovasitol to cause side effects, and this supplement has one of the more favorable safety profiles of any women's health supplement we've reviewed on Illuminate Health.

But can the supplement cause weight loss? We'll discuss that question in the next section.

Can Ovasitol Cause Weight Loss?

Consumers are often curious about whether Ovasitol can cause weight loss. Inositol helps regulate insulin sensitivity, and we know from previous medical research that dysregulated insulin sensitivity is associated with weight gain. 

It logically follows that normalizing insulin sensitivity through supplementation of inositol could theoretically cause weight loss in overweight adults, if unregulated insulin sensitivity was a contributor to their obesity.

Medical research suggests that Ovasitol may cause weight loss in overweight adults.

A 2019 clinical trial on overweight and obese women with PCOS found that myo-inositol supplementation combined with dietary changes caused greater weight loss than dietary changes alone. The dosage used in the study was exactly the same dosage in Ovasitol (4 g).

A separate study on overweight women without PCOS reported similar efficacy. Over a 12 month period, supplementation with inositol caused a 5% decrease in body mass index (BMI), compared with a negligible difference in a control group. 

These results suggest that Ovasitol may be effective for moderate weight loss in overweight women with or without PCOS.

But how do real users rate and describe the effects of Ovasitol? We'll feature unsponsored customer reviews in the next section.

Real People Try Ovasitol

A YouTube creator named Hmong Yeoja shared a 1 year update on her experience with Ovasitol, along with other things she's doing to naturally treat PCOS:

A YouTube creator named Aleksa has a video documenting her experience using inositol, and its effects on PCOS, weight loss, acne and more:

Where to Buy Ovasitol for the Best Price

Ovasitol is sold at a variety of online retailers. Here's a price breakdown for a one-time purchase at the time of updating this article:

Walmart: $148.02 (link)

Amazon: $87 (link)

Brand website: $84 (link)

Currently, Ovasitol is better-priced on the brand's official website than on third-party channels. Shipping is free through the brand's website.

What Does Ovasitol's Certification Mean?

Ovasitol is NSF certified, which is a sign of a quality brand. The NSF is a non-profit organization that analyzes both quality control metrics of manufacturers (like facility inspections for sanitation) and quality control metrics for products (like contaminant levels and label accuracy).

Put simply, a supplement that’s NSF certified is less likely to be contaminated. This is an important consideration in the US supplement market.

In January of 2020, over 800 supplement brands were forced to recall their products by the Food and Drug Administration (FDA) due to failures of good manufacturing practice which may have resulted in tainted supplements.

All things being equal, we would recommend an NSF-certified supplement over a supplement in the same category that's not NSF-certified.

But how do real customers rate and describe the effects of Ovasitol? We'll feature some real customer reviews in the next section.

Real Customers Review Ovasitol

Amazon is a better resource for honest customer reviews than a brand's website in our opinion.

Ovasitol has been reviewed over 6,000 times on Amazon, with an average review rating of 4.6 out of 5 stars.

The top positive review from a verified purchaser is written by a user named "Gbb" who gives the supplement a 5/5 star rating and claims it helped promote menstrual regularity:

"I swear by this product, after a month of taking 1 scoop every day with water my period came and lasted it’s normal 7 days, usually it would last 15+ days!!...I’ve been taking this for 3 months now and can say this product WORKS!!"

The top negative review from a verified purchaser comes from a user named "AJ" who gives the product a 1/5 star rating and claims it caused a number of side effects:

"As soon as I started taking Ovositol, I started having cycles that were about 3 months long with lots of spotting. My progesterone would start rising immediately after my period instead of after ovulation. Additionally, a lot of my pcos symptoms that had resolved with the spironolactone came back. For me, the most concerning was hair loss but I also have worse acne."

The manufacturer of Ovasitol has an average review rating of 1.35/5 stars on the Better Business Bureau (BBB) website, but the brand responds to the majority of customer complaints in an attempt to clarify and rectify the situation, which is a sign of a quality brand.

Pros and Cons of Ovasitol

Here are the pros and cons of Ovasitol in our opinion:

Pros:

  • Effective formulation
  • No unhealthy inactive ingredients
  • Research-backed dosage
  • May be especially effective for women with PCOS
  • Unlikely to cause side effects
  • Favorable online customer reviews
  • NSF-certified
  • Free shipping

Cons:

  • Expensive
  • We can't find clinical studies on this specific supplement
Stay up-to-date on our research reviews

Conclusion

Ovasitol is one of the most impressive women's health supplements that we've reviewed to date on Illuminate Health.

While the supplement itself doesn't appear to be clinically tested, the brand uses research-backed ratios of inositol that are clinically shown to support menstrual regularity and fertility in women with PCOS.

Ovasitol is NSF-certified which is a good sign of quality. It means a third-party organization has ensured that there are no contaminants in the supplement, and that it's accurately labeled.

We do not consider Ovasitol likely to cause side effects in otherwise healthy women, and the brand's website suggests that the supplement does not cause side effects.

Ovasitol may cause weight loss in overweight consumers, but research on this is early-stage.

Most of the customer reviews we came across while researching this article were positive, and the brand's official website currently has the best prices on Ovasitol and offers free shipping.