Inno Cleanse Review: Are Detox Supps Dangerous?

Inno Cleanse Review: Are Detox Supps Dangerous?

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Inno Cleanse is a gut health, detox and weight loss supplement manufactured by Inno Supps, the same company that makes Nitro Wood. The company claims that this supplement can reduce bloating, improve energy levels and help with weight loss.

But does Inno Cleanse contain research-backed ingredients for gut health and weight loss? Does it contain any dangerous ingredients? Will the supplement cause side effects? And how do real users rate and describe its effects?

In this article we’ll answer all of these questions and more, as we analyze the ingredients in Inno Cleanse to give our take on whether or not the supplement is likely to be effective, and whether or not it's healthy.

We’ll share our concerns about some of the ingredient doses, feature real customer reviews, and discuss the risk of side effects.

Ingredient Analysis

Inno Cleanse ingredients

The ingredients in Inno Cleanse are shown above.

The “Waist-Trimming Complex” is the highest-dosed ingredient blend in this supplement, and contains several active ingredients that we consider to be questionable from a health perspective.

Cascara sagrada bark powder is a laxative that may cause liver injury depending on the dose.

A medical review published in the LiverTox journal on this ingredient concludes the following: "The time to onset of liver injury [from cascara use] has varied from a few days to 2 months of use."

Senna is another laxative ingredient that may be harsh on the liver.

As we referenced in our ZuPOO reviews article, this ingredient has been clinically shown to cause liver injury at high doses.

Use of laxatives may cause short-term weight loss due to fluid loss, but they do not cause sustainable long-term weight loss, because laxative use does not cause fat loss.

There are no ingredients in the Waist-Trimming Complex that we consider safe and effective for weight loss.

Fennel seed powder is the first ingredient in the “Advanced Digestion Complex,” and this ingredient is also described as a laxative in a 2022 medical review.

Using three separate laxatives may be harsh on the gut, rather than healing.

Slippery elm bark powder is a potentially effective ingredient for gut health, as it was found in a 2010 clinical trial to reduce irritable bowel syndrome (IBS) symptoms in combination with other natural ingredients.

The “Pro Gut Health Matrix” contains ingredients at such low doses that we consider them unlikely to be effective.

Capiscum annum fruit powder is more commonly known as cayenne pepper.

This is the same ingredient you can find in the spice aisle at a grocery store. The average ingredient dose in this blend is 20 milligrams (mg).

One single tablespoon of cayenne pepper has a dose of 5,300 mg according to the USDA, which means that one single tablespoon of cayenne contains a dose 2,600x higher than the amount in Inno Cleanse.

Overall, we consider this to be a poorly formulated supplement, as we are unable to identify any ingredients we consider effective for either weight loss or gut health at the stated dose.

We do not believe that Inno Cleanse is likely to be effective for weight loss or gut health.

Real People Try Inno Cleanse

A Youtube creator named “Serious Keto” tried Inno Cleanse for 30 days to determine if it caused weight loss or any other effects:

A TikTok creator named Emma Colsey-Nicholls shared her experience taking Inno Cleanse:


Inno Supps review and nupdate. The Inno Cleanse be cleansing, feeling like i dont want to be too far away from a toilet at any time 🥺

♬ original sound - Emma Colsey-Nicholls

Does Inno Cleanse Cause Side Effects?

Inno Cleanse does not appear to have been studied in any clinical trials, so it’s challenging to say for certain whether or not it causes side effects.

However, we can make an educated guess based on its ingredients. 

Because Inno Cleanse contains three separate laxative ingredients, it may be a higher-risk supplement in regard to digestive side effects than the average gut health supplement.

As an example, Cascara sagrada can cause cramps in the intestines and even electrolyte imbalances due to its diuretic and laxative properties, according to a medical review published in the Chemical Research in Toxicology journal.

A medical review on the use of senna in children to treat constipation found that 13% of patients experienced abdominal cramping, vomiting or diarrhea.

We consider Inno Cleanse moderately likely to cause side effects such as digestive upset due to the multiple laxatives it contains.

Do “Cleanses” Even Make Logical Sense?

The entire concept of “cleansing” with the use of a dietary supplement is questionable in our opinion, as we haven’t come across any clinical evidence that this type of treatment is useful or necessary.

As we discussed in our Detoxify Mega Clean reviews article, the purpose of the liver and kidneys is to detoxify the body, and we haven’t come across any medical studies suggesting that additional, supplemental detoxification is necessary.

Individuals may feel as though they are experiencing a “detox” when they defecate more due to the use of laxatives, but taking laxatives simply accelerates the process of digestion and defecation. It’s not “cleansing” the body or digestive tract in any way.

Dr. Jen Caudle explains whether or not cleanses work for weight loss, and other potential health effects, in a video on her YouTube page:

Customers Rate Inno Cleanse

Amazon is a better resource for honest customer reviews than a brand’s website in our opinion.

At the time of updating this article, Inno Cleanse has been reviewed over 9,000 times on Amazon, with an average review rating of 4 out of 5 stars.

A top positive review from a verified purchaser comes from a user named “Katie tran” who gave the product a 5/5 rating:

“Let me tell you when I say this stuff works, it works. My man took it for the first time today and he’s been in the bathroom more than he’s been with me. Talk about a cleanse detox! Like he moves slightly and you can tell he’s been releasing gas all day.”

A top negative review from a verified purchaser is written by a user named “Ross Fazekas” who gave the product a 1/5 rating:

“Well, after taking 2 pills per day for 3 days I had no purging or cleansing action happening at all.

Product didn't work for me so I'll return it for my money back. Amazon stated that this product was "not eligible for return" with no satisfactory explanation why. They advertise it as "100% money back guarantee". Not cool to give no refund.

So I contacted Inno Supps directly for a refund. They refused a refund. Said I had to get it from Amazon. I told them their selling partner would not refund so Inno Supps should. Especially since they are advertising on Amazon as "100% money back guarantee". No dice they said. False advertising.”

Inno Cleanse currently has an average rating of 4.6 out of 5 stars on Google.

Inno Supps currently has a 92% recommendation rating on Facebook.

Our Clean Gut Health Picks

MBG Organic Fiber Potency+ is our top fiber pick.

MBG Organic Fiber Potency+ contains 100% soluble fiber, which was described as "one of the most important nutrients for the gut microbiota" in a clinical review published in the Molecules journal.

Ritual Synbiotic+ is our top value probiotic pick.

It contains prebiotics, probiotics and postbiotics, and costs under $1.50 per serving at the time of updating this article.

Probiotics "can improve in the immune, systems in healthy adults" according to a 2019 medical review.

VSL#3 is our top premium probiotic pick.

This probiotic supplement has been studied in 25 clinical trials, and a 2020 meta-study on VSL#3 concluded the following:

"...many studies demonstrated that VSL#3 has a beneficial effect on obesity and diabetes, allergic diseases, nervous systemic diseases, AS, bone diseases, and female reproductive systemic diseases."

All of the products recommended in this section are entirely free of ingredients that we consider to be unhealthy.

Inno Cleanse Pros and Cons

Here are the pros and cons of Inno Cleanse in our opinion:


  • Safe inactive ingredients
  • Positive reviews on Facebook
  • Positive reviews on Google


  • Questionable active ingredients
  • Contains three separate laxatives
  • "Cleanse" supplements may be unnecessary
  • May cause digestive upset
  • Doesn't appear to be clinically tested
  • One customer complained that money-back guarantee wasn't honored
Stay up-to-date on our research reviews


Inno Cleanse contains a number of laxatives which may cause temporary weight loss due to loss of water weight and fecal matter, however we do not consider this supplement likely to be effective for long-term weight loss or improved gut health.

We are unable to identify any active ingredients in Inno Cleanse that are shown in clinical trials to be effective for the stated health claims, and we do not recommend the supplement overall.

When we initially published this article, we noted that the Supplement Facts panel on the Inno Supps website for this product was missing inactive ingredients, which is a consumer safety issue.

Since, the brand appears to have published the inactive ingredient list, and the inactive ingredients should be safe and non-toxic, which is a good sign.

Inno Cleanse may cause side effects like indigestion and nausea due to the three laxative ingredients it contains. Some of these laxative ingredients are associated with risk of liver injury when taken at high doses.