{"id":605917937970,"title":"Does Inositol Improve Sleep? A Research Review","created_at":"2023-07-19T23:41:35-04:00","body_html":"\u003cscript type=\"application\/ld+json\"\u003e\/\/ \u003c![CDATA[\n{\n \"@context\": \"https:\/\/schema.org\",\n \"@type\": \"Article\",\n \"headline\": \"Does Inositol Improve Sleep? A Research Review\",\n \"keywords\": \"inositol sleep, inositol for sleep, inositol dosage for sleep\",\n \"description\": \"Our research team analyzes medical studies on inositol for sleep to determine if the supplement is safe and effective, or if it's a waste of money. We feature unsponsored user reviews and share which retailer sells inositol for the best price.\",\n \"url\": \"https:\/\/illuminatelabs.org\/blogs\/health\/inositol-for-sleep\",\n\"author\": {\n \"@type\": \"Person\",\n \"name\": \"Calloway Cook\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/calloway-cook\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/calloway-cook\/\",\n \"jobTitle\": \"President\",\n \"knowsAbout\": \"entrepreneurship, dietary supplements, herbal supplements, eCommerce, medical research\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": \"S.I. Newhouse School of Public Communications at Syracuse University\"\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"editor\": {\n \"@type\": \"Person\",\n \"name\": \"Taylor Graber\",\n \"honorificSuffix\": \"M.D.\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/taylor-graber\",\n \"sameAs\": [\n \"https:\/\/www.linkedin.com\/in\/taylor-j-graber-md-81351642\/\",\n \"https:\/\/www.asapivs.com\/\"\n ],\n \"jobTitle\": \"Content Partner\",\n \"knowsAbout\": \"medicine, health, anesthesiology, iv therapy, science, drugs, pharmaceutical, medical research, scientific research, medical journals, entrepreneurship, healthcare, orthopedic surgery, biomedical engineering\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"University of California San Diego\",\n \"Arizona University\",\n \"University of Arizona College of Medicine\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"image\": {\n\"@type\": \"ImageObject\",\n\"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Inositol_For_Sleep_Thumbnail_Optimized.png?v=1689825116\",\n\"width\": \"2500\",\n\"height\": \"2500\"\n},\n\"citation\": [\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32933356\/\", \n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28793304\/\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7554709\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21845803\/\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5655679\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31714321\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36005255\/\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8700927\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33870919\/\"\n],\n\"mentions\": [{\n \"@type\": \"Thing\",\n \"name\": \"sleep quality\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"sleep duration\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"sleep disorders\"\n },\n {\n \"@type\": \"Person\",\n \"name\": \"Andrew Huberman\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"PCOS\"\n },\n {\n \"@type\": \"Brand\",\n \"name\": \"Life Extension\"\n },\n {\n \"@type\": \"Brand\",\n \"name\": \"NOW Supplements\"\n },\n {\n \"@type\": \"Brand\",\n \"name\": \"Nutricost\"\n }\n],\n\"datePublished\": \"2023-07-19\",\n\"copyrightHolder\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n},\n\"publisher\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\",\n \"url\": \"https:\/\/illuminatelabs.org\/\",\n \"description\": \"Illuminate Labs is the most transparent supplement company in the U.S., and is a leading publisher of research-based health information.\",\n \"knowsAbout\": \"supplements, science, nutrition, exercise, health, medication, pharmaceutical, wellness, diet, weight loss, medical research\",\n \"publishingPrinciples\": \"https:\/\/illuminatelabs.org\/pages\/editorial-guidelines\",\n \"memberOf\": [\n {\n \"@type\": \"Organization\",\n \"name\": \"U.S. Chamber of Commerce\",\n \"url\": \"https:\/\/www.uschamber.com\/\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Certified B Corp\",\n \"url\": \"https:\/\/www.bcorporation.net\/en-us\/\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Natural Products Association\",\n \"url\": \"https:\/\/www.npanational.org\/\"\n }\n ], \n \"logo\": {\n \"@type\": \"ImageObject\",\n \"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Illuminate_Labs_Favicon_48x48_7595c3cc-e27b-47b8-a4fe-edcc7ed9b29a.png?v=1666502785\", \n \"width\": 48,\n \"height\": 48\n},\n \"foundingDate\": \"2019-01-30\",\n \"sameAs\": [\n \"https:\/\/www.instagram.com\/illuminatelabs\",\n \"https:\/\/twitter.com\/illuminatelabs\",\n \"https:\/\/www.linkedin.com\/company\/illuminate-labs-supplements\",\n \"https:\/\/www.youtube.com\/channel\/UCpgSJAsIPb-fZ25djtTxBEA\"\n ]\n }\n}\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Inositol_For_Sleep_Article_Header_Image_Optimized.png?v=1689824480\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cspan class=\"dc\"\u003eI\u003c\/span\u003enositol is a sugar that’s naturally produced by the body, but that can also be found in foods and taken in an isolated form as a supplement. Many health websites and influencers online suggest that inositol can improve sleep.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eBut is there any research backing these claims, or are they just a marketing push to sell inositol? Are there any side effects associated with inositol use? How do real users describe the effects of inositol on their sleep? And what retailer sells inositol for the best price?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn this article we’ll answer all of these questions and more, as we analyze medical studies on inositol for sleep to give our take on whether the supplement is likely to be effective, or if it’s a waste of money.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe’ll discuss side effects, feature unsponsored user reviews of inositol for sleep, and provide a cost breakdown to show which retailer sells this supplement the cheapest.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eDoes Inositol Improve Sleep?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThere have been clinical trials analyzing the effects of inositol on sleep.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA 2022 \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32933356\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e tested the effects of inositol supplementation on sleep in pregnant women. \u003c\/span\u003e\u003cb\u003eInositol not only improved sleep quality, but also sleep duration.\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28793304\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in the \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eNeuropsychobiology\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e journal indirectly suggests that inositol supplementation may be effective for supporting sleep. The researchers found that higher levels of circulating inositol in the brain equated to greater daytime sleepiness in adolescents.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7554709\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in the \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eBiomedicines\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e journal reports that \u003c\/span\u003e\u003cb\u003einositol levels have been clinically shown to be lower in patients with sleep disorders.\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eBased on the available research, we consider inositol potentially effective for improving sleep quality. However, we could only find one clinical trial directly testing inositol on sleep quality, and this trial was in pregnant women, which doesn’t necessarily make it reflective of the broader population.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMore research is needed to conclusively state that inositol is an effective sleep supplement.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eBut before reviewing the safety of inositol, we’ll feature some unsponsored user reviews in the next section.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eReal People Try Inositol for Sleep\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA YouTube creator named Bret Dallas discusses his experience taking inositol as a supplement:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ciframe title=\"YouTube video player\" src=\"https:\/\/www.youtube.com\/embed\/h_I3iYWrrXE\" height=\"315\" width=\"560\" allowfullscreen=\"\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" frameborder=\"0\"\u003e\u003c\/iframe\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA neuroscientist and health influencer named Andrew Huberman discussed the effects of inositol on his sleep quality:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: center;\"\u003e\u003ciframe title=\"INOSITOL Your Way To Success - Andrew Huberman #shorts\" src=\"https:\/\/www.youtube.com\/embed\/YVu0xOIzFCY\" height=\"583\" width=\"328\" allowfullscreen=\"\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" frameborder=\"0\"\u003e\u003c\/iframe\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eDoes Inositol Cause Side Effects?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eInositol may cause side effects in some individuals. However, these side effects appear to be relatively minor.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA 2011 \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21845803\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e on the side effects of inositol documented that \u003c\/span\u003e\u003cb\u003eonly the highest daily dose (12 grams per day) caused side effects, and the side effects reported were mild: nausea, gas and diarrhea.\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5655679\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emeta-analysis\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e on inositol supplementation in women with PCOS published in the \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eEndocrine Connections\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e journal reported no serious side effects.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eBased on the available research, we do not consider inositol supplementation likely to cause side effects in otherwise healthy adults. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eBut what retailer sells inositol for the best price-per-serving? We’ll provide a cost breakdown in the next section.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eWhere to Buy Inositol for the Best Price\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAmazon typically has the cheapest bulk prices on single-ingredient supplements.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eServings per brand vary significantly, so we’ll simplify the cost comparison by sharing the price-per-gram of inositol:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eLife Extension: $0.16 (\u003ca rel=\"sponsored\" href=\"https:\/\/amzn.to\/3sVoD86\"\u003elink\u003c\/a\u003e)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eNOW Supplements: \u003c\/span\u003e\u003cb\u003e$0.06 (free shipping\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e, \u003c\/span\u003e\u003ca href=\"https:\/\/amzn.to\/43sR1Ly\" rel=\"sponsored\"\u003e\u003cspan style=\"font-weight: 400;\"\u003elink to official Amazon listing\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eNutricost: \u003c\/span\u003e\u003cb\u003e$0.06 (free shipping\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e, \u003c\/span\u003e\u003ca href=\"https:\/\/amzn.to\/44QHkaH\" rel=\"sponsored\"\u003e\u003cspan style=\"font-weight: 400;\"\u003elink to official Amazon listing\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAt the time of publishing this article, Nutricost and NOW Supplements provide the best cost on inositol.\u003c\/span\u003e\u003c\/p\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cstrong\u003eOur Clean Sleep Picks\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Sleep_Products_Image.png?v=1679732589\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cmeta charset=\"utf-8\"\u003eThere are sleep products with ingredients and materials clinically shown to improve sleep quality.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"https:\/\/bulletproof.fdf2.net\/LX5bVY\" rel=\"sponsored\"\u003eSleep Mode\u003c\/a\u003e from Bulletproof \u003c\/span\u003e\u003cspan\u003eis our top sleep supplement pick.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eIt contains\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003emelatonin\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ewhich is arguably the most well-studied sleep inducer, along with\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003el-ornithine\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ewhich is an amino acid that's\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24889392\/\"\u003eclinically shown\u003c\/a\u003e\u003cspan\u003e \u003c\/span\u003eto reduce cortisol and improve sleep quality at the same dose as in Sleep Mode.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eInterested consumers can check out Sleep Mode \u003ca href=\"https:\/\/bulletproof.fdf2.net\/LX5bVY\" rel=\"sponsored\"\u003eat this link\u003c\/a\u003e\u003cspan\u003e \u003c\/span\u003eto the product page on Bulletproof's official website, where it currently retails for\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eunder $30\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/shareasale.com\/r.cfm?b=883731\u0026amp;u=3153363\u0026amp;m=66636\u0026amp;urllink=www%2Enolahmattress%2Ecom%2Fproducts%2Fnolah%2Dweighted%2Dbamboo%2Dblanket\u0026amp;afftrack=\" rel=\"sponsored\"\u003e\u003cspan\u003eNolah Weighted Bamboo Blanket\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e is a great option for consumers who prefer non-supplement solutions for sleep. Weighted blankets are clinically shown to improve sleep quality in both \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36005255\/\"\u003e\u003cspan\u003eolder adults\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e and in \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8700927\/\"\u003e\u003cspan\u003echildren\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e, and early research suggests they may also reduce anxiety.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eInterested consumers can check out Nolah Weighted Bamboo Blanket \u003c\/span\u003e\u003ca href=\"https:\/\/shareasale.com\/r.cfm?b=883731\u0026amp;u=3153363\u0026amp;m=66636\u0026amp;urllink=www%2Enolahmattress%2Ecom%2Fproducts%2Fnolah%2Dweighted%2Dbamboo%2Dblanket\u0026amp;afftrack=\" rel=\"sponsored\"\u003e\u003cspan\u003eat this link\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e to the product page on the official brand website, where it’s currently retailing for under $100.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/mantasleep.com\/products\/manta-sleep-mask?rfsn=7058102.5070479\u0026amp;utm_source=refersion\u0026amp;utm_medium=affiliate\u0026amp;utm_campaign=7058102.5070479\" rel=\"sponsored\"\u003e\u003cspan\u003eManta Sleep Mask\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e is the most cost-effective sleep solution, because it’s only $35 and will last for years. A 2021 \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33870919\/\"\u003e\u003cspan\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e found that \u003c\/span\u003e\u003cb\u003eeye mask and ear plug use improved sleep quality in ICU patients.\u003c\/b\u003e\u003cspan\u003e Manta’s mask comes with ear plugs.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eWe can't locate any medical studies on sleep mask use in healthy patients, but it seems logical that the same effects would hold given that light exposure during sleep negatively impacts sleep quality.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eInterested consumers can check out Manta Sleep Mask \u003c\/span\u003e\u003ca href=\"https:\/\/mantasleep.com\/products\/manta-sleep-mask?rfsn=7058102.5070479\u0026amp;utm_source=refersion\u0026amp;utm_medium=affiliate\u0026amp;utm_campaign=7058102.5070479\" rel=\"sponsored\"\u003e\u003cspan\u003eat this link\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e to the product page on the official brand website.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eConclusion\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eInositol appears to be a non-toxic supplement that can support optimal sleep.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe don’t currently recommend inositol as a sleep supplement because we could only find one clinical trial proving it to be effective, and that trial was on a specific population segment so it doesn’t necessarily apply to the average consumer.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIf more research emerges in the future proving inositol to optimize sleep quality and duration, we’ll consider recommending this supplement in our sleep-related articles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMost of the user reviews on inositol supplementation that we came across while researching this article were positive.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAt the time of publishing this article, NOW Supplements and Nutricost have the best prices on inositol.\u003c\/span\u003e\u003c\/p\u003e","blog_id":49281925193,"author":"Calloway Cook","user_id":26601750601,"published_at":"2023-07-19T23:53:59-04:00","updated_at":"2023-10-01T19:35:10-04:00","summary_html":"Our research team analyzes medical studies on inositol for sleep to determine if the supplement is safe and effective, or if it's a waste of money. We feature unsponsored user reviews and share which retailer sells inositol for the best price.","template_suffix":"","handle":"inositol-for-sleep","tags":"_related:sleep"}

Does Inositol Improve Sleep? A Research Review

Does Inositol Improve Sleep? A Research Review


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Inositol is a sugar that’s naturally produced by the body, but that can also be found in foods and taken in an isolated form as a supplement. Many health websites and influencers online suggest that inositol can improve sleep.

But is there any research backing these claims, or are they just a marketing push to sell inositol? Are there any side effects associated with inositol use? How do real users describe the effects of inositol on their sleep? And what retailer sells inositol for the best price?

In this article we’ll answer all of these questions and more, as we analyze medical studies on inositol for sleep to give our take on whether the supplement is likely to be effective, or if it’s a waste of money.

We’ll discuss side effects, feature unsponsored user reviews of inositol for sleep, and provide a cost breakdown to show which retailer sells this supplement the cheapest.

Does Inositol Improve Sleep?

There have been clinical trials analyzing the effects of inositol on sleep.

A 2022 clinical trial tested the effects of inositol supplementation on sleep in pregnant women. Inositol not only improved sleep quality, but also sleep duration.

A clinical trial published in the Neuropsychobiology journal indirectly suggests that inositol supplementation may be effective for supporting sleep. The researchers found that higher levels of circulating inositol in the brain equated to greater daytime sleepiness in adolescents.

A medical review published in the Biomedicines journal reports that inositol levels have been clinically shown to be lower in patients with sleep disorders.

Based on the available research, we consider inositol potentially effective for improving sleep quality. However, we could only find one clinical trial directly testing inositol on sleep quality, and this trial was in pregnant women, which doesn’t necessarily make it reflective of the broader population.

More research is needed to conclusively state that inositol is an effective sleep supplement.

But before reviewing the safety of inositol, we’ll feature some unsponsored user reviews in the next section.

Real People Try Inositol for Sleep

A YouTube creator named Bret Dallas discusses his experience taking inositol as a supplement:

A neuroscientist and health influencer named Andrew Huberman discussed the effects of inositol on his sleep quality:

Does Inositol Cause Side Effects?

Inositol may cause side effects in some individuals. However, these side effects appear to be relatively minor.

A 2011 medical review on the side effects of inositol documented that only the highest daily dose (12 grams per day) caused side effects, and the side effects reported were mild: nausea, gas and diarrhea.

A meta-analysis on inositol supplementation in women with PCOS published in the Endocrine Connections journal reported no serious side effects.

Based on the available research, we do not consider inositol supplementation likely to cause side effects in otherwise healthy adults. 

But what retailer sells inositol for the best price-per-serving? We’ll provide a cost breakdown in the next section.

Where to Buy Inositol for the Best Price

Amazon typically has the cheapest bulk prices on single-ingredient supplements.

Servings per brand vary significantly, so we’ll simplify the cost comparison by sharing the price-per-gram of inositol:

Life Extension: $0.16 (link)

NOW Supplements: $0.06 (free shipping, link to official Amazon listing)

Nutricost: $0.06 (free shipping, link to official Amazon listing)

At the time of publishing this article, Nutricost and NOW Supplements provide the best cost on inositol.

Our Clean Sleep Picks

There are sleep products with ingredients and materials clinically shown to improve sleep quality.

Sleep Mode from Bulletproof is our top sleep supplement pick.

It contains melatonin which is arguably the most well-studied sleep inducer, along with l-ornithine which is an amino acid that's clinically shown to reduce cortisol and improve sleep quality at the same dose as in Sleep Mode.

Interested consumers can check out Sleep Mode at this link to the product page on Bulletproof's official website, where it currently retails for under $30.

Nolah Weighted Bamboo Blanket is a great option for consumers who prefer non-supplement solutions for sleep. Weighted blankets are clinically shown to improve sleep quality in both older adults and in children, and early research suggests they may also reduce anxiety.

Interested consumers can check out Nolah Weighted Bamboo Blanket at this link to the product page on the official brand website, where it’s currently retailing for under $100.

Manta Sleep Mask is the most cost-effective sleep solution, because it’s only $35 and will last for years. A 2021 clinical trial found that eye mask and ear plug use improved sleep quality in ICU patients. Manta’s mask comes with ear plugs.

We can't locate any medical studies on sleep mask use in healthy patients, but it seems logical that the same effects would hold given that light exposure during sleep negatively impacts sleep quality.

Interested consumers can check out Manta Sleep Mask at this link to the product page on the official brand website.

Stay up-to-date on our research reviews

Conclusion

Inositol appears to be a non-toxic supplement that can support optimal sleep.

We don’t currently recommend inositol as a sleep supplement because we could only find one clinical trial proving it to be effective, and that trial was on a specific population segment so it doesn’t necessarily apply to the average consumer.

If more research emerges in the future proving inositol to optimize sleep quality and duration, we’ll consider recommending this supplement in our sleep-related articles.

Most of the user reviews on inositol supplementation that we came across while researching this article were positive.

At the time of publishing this article, NOW Supplements and Nutricost have the best prices on inositol.