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{"id":556149669961,"title":"Bio Complete 3 Review: Can It Optimize Gut Health?","created_at":"2022-01-27T09:23:03-05:00","body_html":"\u003cscript type=\"application\/ld+json\"\u003e\/\/ \u003c![CDATA[\n{\n \"@context\": \"https:\/\/schema.org\",\n \"@type\": \"Article\",\n \"headline\": \"Bio Complete 3 Review: Can It Optimize Gut Health?\",\n \"keywords\": \"bio complete 3, bio complete 3 reviews, bio 3 complete, gundry md bio complete 3, gundry md, bio complete 3 scam\",\n \"description\": \"Our MD and research team reviews the ingredients in Bio Complete 3 to determine whether it’s likely to improve gut function and help with weight loss as the brand claims. We highlight some issues we have with their health claims.\",\n \"url\": \"https:\/\/illuminatelabs.org\/blogs\/health\/bio-complete-3-review\",\n\"author\": {\n \"@type\": \"Person\",\n \"name\": \"Taylor Graber MD\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/taylor-graber\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/taylor-j-graber-md-81351642\/\",\n \"jobTitle\": \"Content Partner\",\n \"knowsAbout\": \"medicine, health, anesthesiology, iv therapy, science, drugs, pharmaceutical, medical research, scientific research, medical journals, entrepreneurship, healthcare, orthopedic surgery, biomedical engineering\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"University of California San Diego\",\n \"Arizona University\",\n \"University of Arizona College of Medicine\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"creator\": {\n \"@type\": \"Person\",\n \"name\": \"Taylor Graber MD\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/taylor-graber\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/taylor-j-graber-md-81351642\/\",\n \"jobTitle\": \"Content Partner\",\n \"knowsAbout\": \"medicine, health, anesthesiology, iv therapy, science, drugs, pharmaceutical, medical research, scientific research, medical journals, entrepreneurship, healthcare, orthopedic surgery, biomedical engineering\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"University of California San Diego\",\n \"Arizona University\",\n \"University of Arizona College of Medicine\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"contributor\": {\n \"@type\": \"Person\",\n \"name\": \"Calloway Cook\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/calloway-cook\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/calloway-cook\/\",\n \"jobTitle\": \"President\",\n \"knowsAbout\": \"entrepreneurship, dietary supplements, herbal supplements, eCommerce, medical research\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": \"S.I. Newhouse School of Public Communications at Syracuse University\"\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"editor\": {\n \"@type\": \"Person\",\n \"name\": \"DJ Mazzoni\",\n \"honorificSuffix\": [\n \"M.S.\",\n \"R.D.\",\n \"C.D.N.\",\n \"C.S.C.S.\"\n ],\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/dj-mazzoni\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/dj-mazzoni-rd-cdn-cscs-00a33038\/\",\n \"jobTitle\": \"Medical Reviewer\",\n \"knowsAbout\": \"exercise, drugs, pharmaceutical, health, workout, strength and conditioning, nutrition, dietetics, medicine, medical research, scientific research, scientific method, healthcare, patient care, wellness\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"State University of New York College Oswego\",\n \"D’Youville College\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"image\": {\n\"@type\": \"ImageObject\",\n\"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Bio_Complete_3_Thumbnail.jpg?v=1643293786\",\n\"width\": \"2257\",\n\"height\": \"2257\"\n},\n\"citation\": [\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7146107\/\", \n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2212352\/\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6034030\/\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4769834\/\",\n\"https:\/\/illuminatelabs.org\/blogs\/health\/probioslim-review\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28222814\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9110583\/\"\n],\n\"mentions\": [{\n \"@type\": \"Thing\",\n \"name\": \"Gundry MD\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"weight loss\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"fiber\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"kefir\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"tempeh\"\n }\n],\n\"datePublished\": \"2022-01-28\",\n\"copyrightHolder\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n},\n\"publisher\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\",\n \"url\": \"https:\/\/illuminatelabs.org\/\",\n \"description\": \"Illuminate Labs is the most transparent supplement company in the U.S., and is a leading publisher of research-based health information.\",\n \"knowsAbout\": \"supplements, science, nutrition, exercise, health, medication, pharmaceutical, wellness, diet, weight loss, medical research\",\n \"publishingPrinciples\": \"https:\/\/illuminatelabs.org\/pages\/editorial-guidelines\",\n \"logo\": {\n \"@type\": \"ImageObject\",\n \"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Illuminate_Labs_Logo.png?v=1641249064\", \n \"width\": 150,\n \"height\": 150\n},\n \"foundingDate\": \"2019-01-30\",\n \"Address\": {\n \"@type\": \"PostalAddress\",\n \"streetAddress\": \"50 Union Street, Unit 9\",\n \"addressLocality\": \"Northampton\",\n \"addressRegion\": \"Massachusetts\",\n \"postalCode\": \"01060\",\n \"addressCountry\": \"US\"\n},\n \"sameAs\": [\n \"https:\/\/www.instagram.com\/illuminatelabs\",\n \"https:\/\/twitter.com\/illuminatelabs\",\n \"https:\/\/www.linkedin.com\/company\/illuminate-labs-supplements\",\n \"https:\/\/www.youtube.com\/channel\/UCpgSJAsIPb-fZ25djtTxBEA\"\n ]\n }\n}\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Bio_Complete_3_Review_Article_Header_Image_Optimized.png?v=1643293763\" alt=\"\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cspan class=\"dc\"\u003eB\u003c\/span\u003eio Complete 3 is a gut health supplement manufactured by Gundry MD. The company claims their product has prebiotic, probiotic and postbiotic ingredients to support optimal gut function. They also make some somewhat surprising health claims for a probiotic supplement, such as potential weight loss and increased energy.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn this article we’ll review the ingredients in Bio Complete 3 to determine whether it’s likely to actually improve gut function, and whether it’s worth the high cost of $69.95 per bottle.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eSince the brand advertises the prebiotic, probiotic and postbiotic function of their supplements, we’ll structure our review to analyze each of these separately.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eIngredient Review - Prebiotics\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Bio_Complete_3_Prebiotic_Ingredients.png?v=1643294413\" alt=\"Bio Complete 3 Prebiotic Ingredients\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThere is one active prebiotic ingredient in Bio Complete 3, which is 200 milligrams (mg) of a fiber product called “\u003c\/span\u003e\u003cb\u003eSunfiber\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e”. It’s made from fermenting Indian guar beans.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThis specialized fiber product appears to be safe and well-tolerated based on medical research, but we haven’t come across any studies suggesting it’s superior to regular fiber from food or supplements.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe know from \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7146107\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eextensive medical research\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e that adequate dietary fiber intake is essential for optimal functioning of the microbiome (bacterial balance of the gut), and metabolism, but if this specialized ingredient isn’t superior to regular fiber intake, then it seems like a much more expensive way to increase fiber intake.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe 200 mg dose of prebiotics in Bio Complete 3 also appears to be very low. Even a \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2212352\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ereview\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e of Sunfiber published in a medical journal highlighted how the World Health Organization (WHO) has a recommended daily fiber intake of 37 grams (g).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e1 g = 1000 mg, so the dose of fiber in Bio Complete 3 is 0.5% of the WHO recommended intake. This is so low as to be essentially worthless in our opinion.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eIngredient Review - Probiotics \u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Bio_Complete_3_Probiotic_Ingredients.png?v=1643294438\" alt=\"Bio Complete 3 probiotic ingredients\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe probiotic in Bio Complete 3 is a patented version of \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eBacillus coagulans\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e called \u003c\/span\u003e\u003cb\u003eProDura\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e. We can’t find any research suggesting this specialized probiotic is superior to other strains of \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eBacillus coagulans\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e for optimizing gut function, or superior to any other type of probiotic.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIt may be effective, but we’re not seeing any research that justifies the added cost over a standard probiotic supplement, and Gundry MD doesn’t provide any.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe also find it strange that the listed dose of ProDura is in milligrams, when probiotics are almost always listed in colony-forming units (CFUs). \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe 16 mg of ProDura appears underdosed when compared to the amount of \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eBacillus coagulans\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e used in medical studies. One \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6034030\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e on probiotic supplementation for Irritable Bowel Syndrome (IBS) used a \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eBacillus coagulans\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e dose of 333.33 mg.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4769834\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eAnother medical study\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e used the exact same Bacillus coagulans dose: 333.33 mg.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eNow maybe ProDura is vastly more efficient, and can provide the same benefit as other strains of the same probiotic species when used in much lower quantities, but we haven’t seen any proof of this, and Gundry MD doesn’t provide any clinical data suggesting so, so we will conclude that the probiotic in Bio Complete 3 is likely to be underdosed and ineffective.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eIngredient Review - Postbiotics\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Bio_Complete_3_Postbiotic_Ingredients.png?v=1643294457\" alt=\"Bio Complete 3 postbiotic ingredients\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eBio Complete 3 includes a “postbiotic” ingredient called \u003c\/span\u003e\u003cb\u003eCoreBiome\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e manufactured by a company called Compound Solutions. It appears to be a short-chain fatty acid because it’s standardized for tributyrin, but Compound Solutions doesn’t even publish what the ingredient is composed of on their website; suggesting instead that users contact them for more info. Not exactly very transparent for a consumable product manufacturer.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe can’t find any medical studies at all proving the efficacy and safety of this ingredient, so we recommend avoiding it.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eMisleading Health Claims\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eBased on the previous research summary, we find it to be misleading that Gundry MD is making health claims about Bio Complete 3.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe company claims their supplement improves gut function, aids in weight loss and can increase energy without linking out to any relevant research proving so.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThere are no clinical trials testing Bio Complete 3 for improving gut function (or for safety), and even the active ingredients used appear to have lacking clinical research behind them based on our review.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIf you’re selling a supplement with a proprietary blend like Bio Complete 3, and do not fund clinical research proving that unique blend is effective, we believe it’s unethical to make aggressive health claims for marketing purposes.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eBetter Alternative\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAs we’ve stated in previous reviews of probiotic supplements like \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/probioslim-review\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eProbioSlim\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e, we don’t feel as though there’s enough clinical evidence to support probiotic supplementation for healthy adults.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eFor patients with specific disease states like IBS, targeted strains of probiotics may be beneficial, but for healthy adults we believe that getting probiotics from food products is a much cheaper, safer and more effective way to optimize gut function.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eFermented foods like \u003c\/span\u003e\u003cb\u003ekefir\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e are a great way to significantly increase your probiotic intake at your next trip to the grocery store. Kefir is a fermented dairy product much like yogurt that’s high in naturally-occurring probiotics. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28222814\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e of studies on kefir consumption found that its intake was associated with improved digestion, and that it may have anti-hypertensive (blood pressure lowering) and anti-inflammatory effect.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAnother healthy fermented food which is even cheaper and more accessible than kefir is \u003c\/span\u003e\u003cb\u003etempeh\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e, which is made from fermented soybeans.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9110583\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ereview\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e of the health benefits of tempeh published in the Nutrition Reviews journal found that it lowered cholesterol levels and reduced incidence of diarrhea, suggesting it’s beneficial for the gut.\u003c\/span\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eNot only are these whole foods probiotics likely to provide more CFU of probiotics than supplements, but they also contain healthy micronutrients which provide additional health benefit beyond the probiotic function.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eConclusion\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe recommend avoiding Bio Complete 3. The manufacturer includes seemingly random amounts of exotic patented ingredients, none of which we believe will be effective based on a review of medical literature.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eGundry MD makes exceptional health claims about Bio Complete 3 but provides no research supporting any of those claims, nor does the company fund research themselves proving their supplement is safe and effective.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe believe that consumption of whole foods probiotics such as kefir and tempeh is a safer, healthier and more effective option for improving microbiome function than supplementing with Bio Complete 3.\u003c\/span\u003e\u003c\/p\u003e","blog_id":49281925193,"author":"Calloway Cook","user_id":26601750601,"published_at":"2022-01-27T18:00:02-05:00","updated_at":"2022-04-09T16:59:06-04:00","summary_html":"We review the ingredients in probiotic supplement Bio Complete 3 to determine whether it’s likely to improve gut function and help with weight loss as the brand claims. We highlight some issues we have with their health claims.","template_suffix":"","handle":"bio-complete-3-review","tags":"_related:gut-health, _related:probiotics"}

Bio Complete 3 Review: Can It Optimize Gut Health?

Bio Complete 3 Review: Can It Optimize Gut Health?


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Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.
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Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.


Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.

Bio Complete 3 is a gut health supplement manufactured by Gundry MD. The company claims their product has prebiotic, probiotic and postbiotic ingredients to support optimal gut function. They also make some somewhat surprising health claims for a probiotic supplement, such as potential weight loss and increased energy.

In this article we’ll review the ingredients in Bio Complete 3 to determine whether it’s likely to actually improve gut function, and whether it’s worth the high cost of $69.95 per bottle.

Since the brand advertises the prebiotic, probiotic and postbiotic function of their supplements, we’ll structure our review to analyze each of these separately.

Ingredient Review - Prebiotics

Bio Complete 3 Prebiotic Ingredients

There is one active prebiotic ingredient in Bio Complete 3, which is 200 milligrams (mg) of a fiber product called “Sunfiber”. It’s made from fermenting Indian guar beans.

This specialized fiber product appears to be safe and well-tolerated based on medical research, but we haven’t come across any studies suggesting it’s superior to regular fiber from food or supplements.

We know from extensive medical research that adequate dietary fiber intake is essential for optimal functioning of the microbiome (bacterial balance of the gut), and metabolism, but if this specialized ingredient isn’t superior to regular fiber intake, then it seems like a much more expensive way to increase fiber intake.

The 200 mg dose of prebiotics in Bio Complete 3 also appears to be very low. Even a review of Sunfiber published in a medical journal highlighted how the World Health Organization (WHO) has a recommended daily fiber intake of 37 grams (g).

1 g = 1000 mg, so the dose of fiber in Bio Complete 3 is 0.5% of the WHO recommended intake. This is so low as to be essentially worthless in our opinion.

Ingredient Review - Probiotics 

Bio Complete 3 probiotic ingredients

The probiotic in Bio Complete 3 is a patented version of Bacillus coagulans called ProDura. We can’t find any research suggesting this specialized probiotic is superior to other strains of Bacillus coagulans for optimizing gut function, or superior to any other type of probiotic.

It may be effective, but we’re not seeing any research that justifies the added cost over a standard probiotic supplement, and Gundry MD doesn’t provide any.

We also find it strange that the listed dose of ProDura is in milligrams, when probiotics are almost always listed in colony-forming units (CFUs). 

The 16 mg of ProDura appears underdosed when compared to the amount of Bacillus coagulans used in medical studies. One clinical trial on probiotic supplementation for Irritable Bowel Syndrome (IBS) used a Bacillus coagulans dose of 333.33 mg.

Another medical study used the exact same Bacillus coagulans dose: 333.33 mg.

Now maybe ProDura is vastly more efficient, and can provide the same benefit as other strains of the same probiotic species when used in much lower quantities, but we haven’t seen any proof of this, and Gundry MD doesn’t provide any clinical data suggesting so, so we will conclude that the probiotic in Bio Complete 3 is likely to be underdosed and ineffective.

Ingredient Review - Postbiotics

Bio Complete 3 postbiotic ingredients

Bio Complete 3 includes a “postbiotic” ingredient called CoreBiome manufactured by a company called Compound Solutions. It appears to be a short-chain fatty acid because it’s standardized for tributyrin, but Compound Solutions doesn’t even publish what the ingredient is composed of on their website; suggesting instead that users contact them for more info. Not exactly very transparent for a consumable product manufacturer.

We can’t find any medical studies at all proving the efficacy and safety of this ingredient, so we recommend avoiding it.

Misleading Health Claims

Based on the previous research summary, we find it to be misleading that Gundry MD is making health claims about Bio Complete 3.

The company claims their supplement improves gut function, aids in weight loss and can increase energy without linking out to any relevant research proving so.

There are no clinical trials testing Bio Complete 3 for improving gut function (or for safety), and even the active ingredients used appear to have lacking clinical research behind them based on our review.

If you’re selling a supplement with a proprietary blend like Bio Complete 3, and do not fund clinical research proving that unique blend is effective, we believe it’s unethical to make aggressive health claims for marketing purposes.

Better Alternative

As we’ve stated in previous reviews of probiotic supplements like ProbioSlim, we don’t feel as though there’s enough clinical evidence to support probiotic supplementation for healthy adults.

For patients with specific disease states like IBS, targeted strains of probiotics may be beneficial, but for healthy adults we believe that getting probiotics from food products is a much cheaper, safer and more effective way to optimize gut function.

Fermented foods like kefir are a great way to significantly increase your probiotic intake at your next trip to the grocery store. Kefir is a fermented dairy product much like yogurt that’s high in naturally-occurring probiotics. 

A medical review of studies on kefir consumption found that its intake was associated with improved digestion, and that it may have anti-hypertensive (blood pressure lowering) and anti-inflammatory effect.

Another healthy fermented food which is even cheaper and more accessible than kefir is tempeh, which is made from fermented soybeans.

A review of the health benefits of tempeh published in the Nutrition Reviews journal found that it lowered cholesterol levels and reduced incidence of diarrhea, suggesting it’s beneficial for the gut.

Not only are these whole foods probiotics likely to provide more CFU of probiotics than supplements, but they also contain healthy micronutrients which provide additional health benefit beyond the probiotic function.

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Conclusion

We recommend avoiding Bio Complete 3. The manufacturer includes seemingly random amounts of exotic patented ingredients, none of which we believe will be effective based on a review of medical literature.

Gundry MD makes exceptional health claims about Bio Complete 3 but provides no research supporting any of those claims, nor does the company fund research themselves proving their supplement is safe and effective.

We believe that consumption of whole foods probiotics such as kefir and tempeh is a safer, healthier and more effective option for improving microbiome function than supplementing with Bio Complete 3.





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