Apetropics One Chews Review: Does CBD Relieve Pain?

Apetropics One Chews Review: Does CBD Relieve Pain?

| |
| |
Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.

Apetropics One Chews is a cannabidiol (CBD) product that’s used for pain relief. The brand claims that using the supplement is “like flipping the ‘ON’ switch to your brain for improved focus…while turning ‘OFF’ aches and pains.”

But is CBD actually effective for pain relief or are these just marketing claims? Do Apetropics One Chews contain other research-backed pain relief ingredients? Does the supplement contain any questionable additive ingredients?

In this article we’ll answer all of these questions and more as we review the ingredients in Apetropics One Chews based on medical studies to give our take on whether the product is likely to be effective for pain relief or if it’s a waste of money.

Does CBD Relieve Pain?

Many consumers use CBD for pain relief and there have been medical studies testing its effectiveness.

A medical review published in the International Journal of Molecular Sciences analyzed data from tens of animal and human studies on how CBD works to achieve pain relief. The study authors concluded that “CBD is a well-tolerated and safe natural compound exerting [pain-relieving] effects in various animal models of pain, as well as clinical studies.”

However, the researchers noted a lack of clinical trials on long-term CBD use for chronic pain. 

As we referenced in our review of Pure Kana CBD Gummies, there’s also a lack of clarity on the effective dosing range of CBD for pain. Some of the clinical trials cited in the medical review included doses below the amount in Apetropics One Chews, but some used doses much higher.

survey of real patients who use CBD for chronic pain, published in the Journal of Pain Research, reports that 59% of patients using CBD for chronic pain find the treatment to provide benefits.

Based on the available research, we conclude that CBD is potentially effective for pain relief. We hope to see more long-term studies on CBD for chronic pain in the future, but the early research is promising.

Apetropics One Chews Ingredient Analysis

Apetropics One Chews ingredients

Apetropics One Chews contain other active ingredients beyond CBD along with some inactive ingredients. The other active ingredients are lion’s mane mushroom extract, cordyceps mushroom extract and black pepper extract.

Lion’s mane mushroom extract was found to have anti-inflammatory effects in a test tube study, but we can’t identify any clinical trials with human participants showing it to have analgesic (pain relieving) effects.

Cordyceps mushroom extract was shown in a 2018 medical review to have potential pain relieving effects, but again these effects don’t appear to have been proven in a clinical trial with human trial subjects. 

Black pepper extract is typically included in supplement formulations to increase the effects and absorption of other active ingredients, as we documented in our review of Golden Revive (another pain relief supplement containing this ingredient).

Unfortunately, while there are some potentially effective ingredients in this formulation, there are also some additive ingredients we recommend avoiding.

Cane sugar is an ingredient to avoid for individuals experiencing pain, because it’s been shown to increase inflammatory processes in the body according to a meta-study published in the Nutrients journal.

Artificial colors have medically-documented toxicity and carcinogenicity concerns, and no nutritive value, so we recommend avoiding them entirely.

Citric acid is a preservative shown to cause “significant inflammatory reactions” in some patients as documented by a series of medical case reports published in the Toxicology Reports journal.

Natural flavors is a broad categorical ingredient definition that fails to describe the specific chemical compounds used as flavoring agents.

Overall we consider this supplement to be potentially effective for pain relief given the effective dose of CBD and the mushroom ingredients. We do not recommend Apetropics One Chews due to the numerous questionable additive ingredients.

Questionable Media Claims

Apetropics fraudulent media claims

The product page for Apetropics One Chews on the Apetropics website has a banner stating that the product is “Trusted By Experts” with various logos of major media institutions.

However, there don’t appear to be experts at some of these companies recommending Apetropics One Chews.

We searched the USA Today website on Google (as shown above) for any mention of the brand Apetropics, and nothing appeared. Our search also returned no results for the Fox News website.

We consider this to be a serious red flag, and we hope that Apetropics clarifies why they are claiming to be associated with experts at these media institutions.

Do Apetropics One Chews Cause Side Effects?

Apetropics One Chews don’t appear to have been studied in any clinical trials, so it’s hard to say for certain whether or not they cause side effects to the average consumer.

We can make an educated guess based on the ingredients.

CBD is very well-studied and unlikely to cause side effects when used at a safe dose like the dose in Apetropics One Chews. This supplement is free of THC which is the psychoactive cannabinoid.

The mushroom ingredients are included at relatively low doses and both have clinical research backing so we don’t consider those likely to cause side effects.

The only ingredients we consider a side effect concern are the citric acid and artificial colorants. It’s shown in clinical research that artificial colorants may cause hyperactivity and neurotoxicity. 

Overall we do not consider this supplement likely to cause side effects, although it contains inactive ingredients that may cause side effects in a small percentage of consumers.

Our Clean Anti-Inflammatory Picks

There are natural compounds which have been shown in clinical studies to support optimal joint health and relieve pain.

Cinnamon was shown to reduce inflammatory markers in a 2020 clinical trialThe study authors concluded that “Cinnamon could be regarded as a safe supplement to relieve pain.”

Illuminate Labs Ceylon Cinnamon Extract is our standardized cinnamon supplement, which is third-party tested for purity and potency and costs only $15 at a subscription price.

Collagen is the core structural protein in joints, and has been clinically shown to reduce arthritic pain.

Bulletproof Collagen Powder is our top collagen supplement pick because it only contains one ingredient: collagen peptides sourced from grass-fed animals.

Cannabidiol (CBD) is clinically shown to be effectively absorbed through the skin, and CBD caused "significant improvements in pain" when applied topically in a 2020 clinical trial.

Cornbread CBD Lotion is our top CBD lotion pick, because it also contains menthol, which was shown in a 2022 clinical trial to reduce pain scores.

All of the products recommended in this section are entirely free of ingredients that we consider to be unhealthy or unsafe.

Stay up-to-date on our research reviews


Apetropics One Chews contains some effective ingredients for pain relief. We consider the supplement to be potentially effective overall, because some of the active ingredients (like CBD) have research backing for long-term treatment of chronic pain.

We do not recommend Apetropics One Chews overall because of the inclusion of questionable additive ingredients like artificial colors, added sugar and more. While it’s true that many other CBD gummies contain similar ingredients, we consider CBD oil to be healthier overall than CBD gummies like Apetropics One Chews because most CBD oil is free of questionable additive ingredients.

The product page of this supplement has a strange claim that it’s “Trusted By Experts” with various major media logos like USA Today. Some of these companies have not mentioned the brand even once on their websites, so we don’t understand how Apetropics is making this claim.

We do not consider Apetropics One Chews likely to cause side effects.