{"id":604894396722,"title":"Mr. Hyde Pre-Workout Review: Loaded With Garbage?","created_at":"2023-02-27T23:22:24-05:00","body_html":"\u003cscript type=\"application\/ld+json\"\u003e\/\/ \u003c![CDATA[\n{\n \"@context\": \"https:\/\/schema.org\",\n \"@type\": \"Article\",\n \"headline\": \"Mr. Hyde Pre-Workout Review: Loaded With Garbage?\",\n \"keywords\": \"mr hyde pre workout, mr hyde pre workout reviews, mr hyde pre workout review, mr hyde pre workout side effects, mr. hyde pre workout, is mr hyde pre workout good\",\n \"description\": \"Our research team reviews the ingredients in Mr. Hyde Pre-Workout based on medical studies to give our take on whether it's likely to be effective or if it's a waste of money. We highlight some questionable additive ingredients and feature real customer reviews.\",\n \"url\": \"https:\/\/illuminatelabs.org\/blogs\/health\/mr-hyde-pre-workout-review\",\n\"author\": {\n \"@type\": \"Person\",\n \"name\": \"Calloway Cook\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/calloway-cook\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/calloway-cook\/\",\n \"jobTitle\": \"President\",\n \"knowsAbout\": \"entrepreneurship, dietary supplements, herbal supplements, eCommerce, medical research\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": \"S.I. Newhouse School of Public Communications at Syracuse University\"\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"editor\": {\n \"@type\": \"Person\",\n \"name\": \"DJ Mazzoni\",\n \"honorificSuffix\": [\n \"M.S.\",\n \"R.D.\",\n \"C.D.N.\",\n \"C.S.C.S.\"\n ],\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/dj-mazzoni\",\n \"sameAs\": [\n \"https:\/\/www.linkedin.com\/in\/dj-mazzoni-rd-cdn-cscs-00a33038\/\",\n \"http:\/\/djmazzoni.com\/\"\n ],\n \"jobTitle\": \"Medical Reviewer\",\n \"knowsAbout\": \"exercise, drugs, pharmaceutical, health, workout, strength and conditioning, nutrition, dietetics, medicine, medical research, scientific research, scientific method, healthcare, patient care, wellness\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"State University of New York College Oswego\",\n \"D’Youville College\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"image\": {\n\"@type\": \"ImageObject\",\n\"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Mr_Hyde_Pre_Workout_Thumbnail.png?v=1677558440\",\n\"width\": \"3948\",\n\"height\": \"3948\"\n},\n\"citation\": [\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32833890\/\", \n\"https:\/\/illuminatelabs.org\/blogs\/health\/con-cret-creatine-review\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34291426\/\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7041093\/\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3435905\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23026007\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28832835\/\",\n\"https:\/\/illuminatelabs.org\/blogs\/health\/feel-great-system-review\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6097542\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15093265\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22777329\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15982990\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29624410\/\",\n\"https:\/\/illuminatelabs.org\/products\/panax-ginseng-extract\"\n],\n\"mentions\": [{\n \"@type\": \"Brand\",\n \"name\": \"ProSupps\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"beta alanine\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"caffeine\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"artificial food dye\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"artificial flavors\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"FDA\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Walmart\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Amazon\"\n }\n],\n\"datePublished\": \"2023-02-27\",\n\"copyrightHolder\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n},\n\"publisher\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\",\n \"url\": \"https:\/\/illuminatelabs.org\/\",\n \"description\": \"Illuminate Labs is the most transparent supplement company in the U.S., and is a leading publisher of research-based health information.\",\n \"knowsAbout\": \"supplements, science, nutrition, exercise, health, medication, pharmaceutical, wellness, diet, weight loss, medical research\",\n \"publishingPrinciples\": \"https:\/\/illuminatelabs.org\/pages\/editorial-guidelines\",\n \"memberOf\": [\n {\n \"@type\": \"Organization\",\n \"name\": \"U.S. Chamber of Commerce\",\n \"url\": \"https:\/\/www.uschamber.com\/\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Certified B Corp\",\n \"url\": \"https:\/\/www.bcorporation.net\/en-us\/\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Natural Products Association\",\n \"url\": \"https:\/\/www.npanational.org\/\"\n }\n ], \n \"logo\": {\n \"@type\": \"ImageObject\",\n \"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Illuminate_Labs_Favicon_48x48_7595c3cc-e27b-47b8-a4fe-edcc7ed9b29a.png?v=1666502785\", \n \"width\": 48,\n \"height\": 48\n},\n \"foundingDate\": \"2019-01-30\",\n \"sameAs\": [\n \"https:\/\/www.instagram.com\/illuminatelabs\",\n \"https:\/\/twitter.com\/illuminatelabs\",\n \"https:\/\/www.linkedin.com\/company\/illuminate-labs-supplements\",\n \"https:\/\/www.youtube.com\/channel\/UCpgSJAsIPb-fZ25djtTxBEA\"\n ]\n }\n}\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Mr_Hyde_Pre_Workout_Review_Article_Header_Image_Optimized.png?v=1677557928\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cspan class=\"dc\"\u003eM\u003c\/span\u003er. Hyde Pre-Workout is a supplement sold by ProSupps. The brand claims that it can provide “clean energy” to fuel you physically, and also that it increases mental focus and energy.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eBut does Mr. Hyde Pre-Workout contain research-backed ingredients for improving energy? What about for increasing strength? Does it contain any unhealthy additive ingredients? And how do real users rate and describe the effects of Mr. Hyde Pre-Workout?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn this article we’ll answer all of these questions and more as we analyze the ingredients in Mr. Hyde Pre-Workout based on medical studies to give our take on whether it’s likely to be effective or if it’s a waste of money.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe’ll share our thoughts about whether the supplement is likely to cause side effects, explain why it was recalled in the past, and feature real, unsponsored Mr. Hyde Pre-Workout user reviews.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThis supplement contains a wide range of ingredients so we’ll break our ingredient analysis into two sections: active ingredient analysis and inactive ingredient analysis.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eActive Ingredient Analysis\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg style=\"display: block; margin-left: auto; margin-right: auto;\" alt=\"Mr. Hyde Pre-Workout active ingredients\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Mr_Hyde_Pre_Workout_Active_Ingredients_Optimized.png?v=1677557952\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe active ingredients in Mr. Hyde Pre-Workout are shown above.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eBeta alanine\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is an effective ingredient that can increase power. A \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32833890\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe Journal of Strength and Conditioning Research\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e found that this ingredient prevented fatigue and increased power in athletes at a 1.2 gram (g) dose, which is less than that in Mr. Hyde.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCreatine\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e can also increase power, but may be underdosed at only 1 g dose. As we documented in our \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/con-cret-creatine-review\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eCon Cret Creatine review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e article, clinical research suggests that the effective maintenance creatine dose is around 2.5 g.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCaffeine\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is included in almost all pre-workout supplements, and for good reason. A \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34291426\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in the \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eSports Medicine\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e journal found that it increases power and reduces fatigue. The 169 milligram (mg) dose in Mr. Hyde Pre-Workout is an effective dose.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eNitrosigine\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e and \u003c\/span\u003e\u003cb\u003ecitrulline\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e are shown in a 2020 \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7041093\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e to increase blood flow in young athletes, but at a dose of 1.5 g and 8 g, respectively. The doses in Mr. Hyde are only 500 mg and 500 mg, and we can’t find clinical evidence backing such low doses.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCholine\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is often included in pre-workout supplements, but we’re not sure why. A \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3435905\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in the \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eSports Health\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e journal analyzed data from three clinical trials on choline supplementation, and found that there was no significant benefit in any of the three trials.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe remaining active ingredients are included at too low of a dose to have any benefit for exercise performance in our opinion.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eOverall, we consider Mr. Hyde likely to improve exercise performance and endurance given its effective dose of caffeine and beta alanine.\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e However, we aren’t particularly impressed with the formulation given that this is two active ingredients that we consider effectively dosed out of 11 total.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eBut the main reason we recommend avoiding Mr. Hyde Pre-Workout is due to its inactive ingredients, which we’ll examine in the next section.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eInactive Ingredient Analysis\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg style=\"display: block; margin-left: auto; margin-right: auto;\" alt=\"Mr. Hyde inactive ingredients\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Mr_Hyde_Pre_Workout_Inactive_Ingredients_Optimized.png?v=1677558007\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThere are a number of inactive ingredients in this pre-workout powder that we consider questionable from a health perspective.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eFD\u0026amp;C Blue #1\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is an artificial food dye. A \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23026007\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e on the toxicology of food dyes reported negative health effects from all currently-approved food dyes.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eArtificial flavors\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e were shown in a \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28832835\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e on animals to be toxic.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eSucralose\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is an artificial sweetener shown to cause negative changes to insulin levels, as we referenced in our review of \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/feel-great-system-review\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ethe Feel Great System\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eAcesulfame potassium\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is another artificial sweetener.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCitric acid\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is commonly derived from a fungus when used in manufacturing, and is \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6097542\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinically shown\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e to cause whole-body inflammation in a small subset of individuals.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eNatural flavors\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is a healthier choice than artificial flavors in our opinion, but there are toxicity concerns regarding some natural flavoring agents \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15093265\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ein clinical research\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThis is one of the longest lists of questionable inactive ingredients in any supplement we’ve reviewed on Illuminate Health. But how do real users describe the supplement’s effects? We’ll review in the next section.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cstrong\u003eWhy Was Mr. Hyde Pre-Workout Recalled?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMr. Hyde Pre-Workout was recalled in 2016 \u003ca href=\"https:\/\/clarksnutrition.com\/index.php\/blog\/recalls\/2016\/04\/recall-dr-jeykll-mr-hyde-dietary-supplements\"\u003eaccording to\u003c\/a\u003e Clark's Nutrition. The recall was apparently due to an unapproved drug ingredient called picamilon being included. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003ePicamilon is not allowed for use in dietary supplements \u003ca href=\"https:\/\/www.fda.gov\/food\/dietary-supplement-products-ingredients\/picamilon-dietary-supplements\"\u003eaccording to\u003c\/a\u003e the FDA, and has lacking safety data.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eProSupps also received a \u003ca href=\"https:\/\/www.fda.gov\/inspections-compliance-enforcement-and-criminal-investigations\/warning-letters\/prosupps-usa-llc-505396-02032017\"\u003ewarning letter\u003c\/a\u003e from the FDA in 2017 for \"significant violations\" of good manufacturing practice. According to the letter, \u003cstrong\u003ethe manufacturer of Dr. Hyde failed to follow written procedures for the investigation of customer complaints, and failed to establish proper quality control procedures.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThis is a red flag about the company as a whole in our opinion.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cstrong\u003eReal, Unsponsored Mr. Hyde Pre-Workout Reviews\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA YouTube fitness creator named “b5lifting” reviewed Mr. Hyde Pre-Workout:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: center;\"\u003e\u003ciframe title=\"Mr.Hyde pre workout review\" src=\"https:\/\/www.youtube.com\/embed\/uy_8v1yD1Mw\" height=\"583\" width=\"328\" allowfullscreen=\"\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" frameborder=\"0\"\u003e\u003c\/iframe\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA TikTok fitness influencer named Andrew Burgess gave the pre-workout a mediocre score:\u003c\/span\u003e\u003c\/p\u003e\n\u003cblockquote style=\"max-width: 375px; min-width: 325px;\" data-video-id=\"6967382374392810757\" cite=\"https:\/\/www.tiktok.com\/@andrewburgessfit\/video\/6967382374392810757\" class=\"tiktok-embed\"\u003e\n\u003csection\u003e\u003ca href=\"https:\/\/www.tiktok.com\/@andrewburgessfit?refer=embed\" title=\"@andrewburgessfit\" target=\"_blank\"\u003e@andrewburgessfit\u003c\/a\u003e Supplement Reviews Part 1: Mr. Hyde! \u003ca href=\"https:\/\/www.tiktok.com\/tag\/gains?refer=embed\" title=\"gains\" target=\"_blank\"\u003e#gains\u003c\/a\u003e \u003ca href=\"https:\/\/www.tiktok.com\/tag\/fitness?refer=embed\" title=\"fitness\" target=\"_blank\"\u003e#fitness\u003c\/a\u003e \u003ca href=\"https:\/\/www.tiktok.com\/tag\/gymlife?refer=embed\" title=\"gymlife\" target=\"_blank\"\u003e#gymlife\u003c\/a\u003e \u003ca href=\"https:\/\/www.tiktok.com\/tag\/preworkout?refer=embed\" title=\"preworkout\" target=\"_blank\"\u003e#preworkout\u003c\/a\u003e \u003ca href=\"https:\/\/www.tiktok.com\/music\/original-sound-6967382355036801797?refer=embed\" title=\"♬ original sound - Andrew Burgess\" target=\"_blank\"\u003e♬ original sound - Andrew Burgess\u003c\/a\u003e\u003c\/section\u003e\n\u003c\/blockquote\u003e\n\u003cscript async=\"\" src=\"https:\/\/www.tiktok.com\/embed.js\"\u003e\u003c\/script\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eWill Mr. Hyde Pre-Workout Cause Side Effects?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMr. Hyde Pre-Workout doesn’t appear to have been studied in any clinical trials, so it’s impossible to say for certain whether or not it causes side effects. However, we can make an educated guess based on its active ingredients.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePre-workouts are generally more likely to cause side effects than most supplements due to all of the stimulants they contain.\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eCaffeine can cause jitteriness and anxiety in those who are caffeine sensitive, though the dose in Mr. Hyde is only around two cups of coffee which probably won’t have a negative effect on most individuals.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eBeta alanine has been shown in a 2012 \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22777329\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e to cause an uncomfortable tingling sensation at the dose included in Mr. Hyde, and this side effect is also reported by a number of individuals online.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eArtificial dyes like Blue 1 can cause hyperactivity in some people (especially in children and adolescents) according to the medical review linked in the inactive ingredient section.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe consider Mr. Hyde somewhat likely to cause side effects overall.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eWhere to Buy Mr. Hyde Pre-Workout for the Best Price\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMr. Hyde Pre-Workout is sold at a variety of online retailers. Here’s the price breakdown at the time of publishing this article:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eBrand website: $19.98 (plus $7.95 shipping, \u003ca href=\"https:\/\/www.prosupps.com\/products\/mr-hyde-signature?variant=40518717964473\"\u003elink\u003c\/a\u003e)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWalmart: $19.98 (plus $6.99 shipping, \u003ca href=\"https:\/\/www.walmart.com\/ip\/Mr-Hyde-Signature-Pre-Workout-Blue-Razz-Popsicle-30-Servings\/252186584\"\u003elink\u003c\/a\u003e)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAmazon: \u003c\/span\u003e\u003cb\u003e$19.98 (free shipping\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e depending on plan – \u003c\/span\u003e\u003ca href=\"https:\/\/amzn.to\/3KM1OdZ\"\u003e\u003cspan style=\"font-weight: 400;\"\u003elink to official Amazon listing\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThose who can get free shipping on Amazon reduce the overall price by around 25%.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eReal Customer Reviews of Mr. Hyde Pre-Workout\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAmazon reviews are a more honest source of customer reviews than a brand’s website in our opinion. Mr. Hyde Pre-Workout has an average review rating of 4.4 out of 5 and has been reviewed over 10,000 times on Amazon.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe top positive review from a verified purchaser is written by a user named “Ella” who claims the product is powerful:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e“Great workout powder! I only use half of scoop as I feel a full scoop is too much for me but it really helps with my 5am workouts!”\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe top negative review from a verified purchaser comes from a user named “Lorenzo Aranda” who’s upset about a recent reduction in the ingredient potency:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e“Did anyone else notice the difference in color now? \u003c\/span\u003e\u003cb\u003eHow about the fact that they halved the concentration of the key ingredients for the same price? Sneaky. Essentially it’s just fluff loaded with caffeine.”\u003c\/b\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eOur Clean Pre-Workout Picks\u003c\/b\u003e\u003c\/h2\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003e\u003cspan\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Pre-Workout_Image.png?v=1672460783\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe pre-workout supplement we recommend is \u003c\/span\u003e\u003ca href=\"https:\/\/shareasale.com\/r.cfm?b=1150909\u0026amp;u=3153363\u0026amp;m=78253\u0026amp;urllink=nakednutrition%2Ecom%2Fproducts%2Fpre%2Dworkout%2Dpowder\u0026amp;afftrack=\" rel=\"sponsored\"\u003e\u003cspan\u003eNaked Energy\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e by Naked Nutrition.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eLike Mr. Hyde, it provides an effective dose of \u003c\/span\u003e\u003cb\u003ebeta alanine\u003c\/b\u003e\u003cspan\u003e and \u003c\/span\u003e\u003cb\u003ecaffeine\u003c\/b\u003e\u003cspan\u003e for power and stamina improvements.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe main difference is that it’s entirely free of questionable additive ingredients like artificial sweeteners and artificial colors. There are no inactive ingredients in this formulation at all, which makes it the healthiest pre-workout formulation on the market in our opinion.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eInterested consumers can check out Naked Energy \u003c\/span\u003e\u003ca href=\"https:\/\/shareasale.com\/r.cfm?b=1150909\u0026amp;u=3153363\u0026amp;m=78253\u0026amp;urllink=nakednutrition%2Ecom%2Fproducts%2Fpre%2Dworkout%2Dpowder\u0026amp;afftrack=\" rel=\"sponsored\"\u003e\u003cspan\u003eat this link\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e to its product page on the official brand website.\u003c\/span\u003e\u003c\/p\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003e\u003cb\u003e\u003ci\u003ePanax ginseng\u003c\/i\u003e\u003c\/b\u003e\u003cspan\u003e is clinically shown to reduce mental fatigue (\u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15982990\/\"\u003e\u003cspan\u003esource\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e) and reduce physical fatigue (\u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29624410\/\"\u003e\u003cspan\u003esource\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e). It’s one of the most popular herbal supplements in the world.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIlluminate Labs sells a \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/products\/panax-ginseng-extract\"\u003e\u003cspan\u003ePanax Ginseng extract supplement\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e for only \u003c\/span\u003e\u003cb\u003e$15\u003c\/b\u003e\u003cspan\u003e on a subscription basis which is highly potent (minimum 8% ginsenosides) and is third-party tested to ensure label accuracy and purity. Interested consumers can check out Illuminate Labs Panax Ginseng Extract \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/products\/panax-ginseng-extract\"\u003e\u003cspan\u003eat this link\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e to the product page on our website.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eConclusion\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMr. Hyde Pre-Workout is likely to improve workout performance, and it’s sold at a great price. However, the downsides are that the formulation contains a large number of active ingredients that we consider underdosed, and it also has inactive ingredients like artificial flavors and artificial food dye that are questionable from a health perspective.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThis pre-workout may cause side effects in individuals who are sensitive to caffeine or stimulants, but so will most pre-workouts.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAmazon currently has the best price on Mr. Hyde Pre-Workout when considering shipping costs.\u003c\/span\u003e\u003c\/p\u003e","blog_id":49281925193,"author":"Calloway Cook","user_id":26601750601,"published_at":"2023-02-27T23:40:36-05:00","updated_at":"2023-09-11T17:45:47-04:00","summary_html":"We review the ingredients in Mr. Hyde Pre-Workout based on medical studies to give our take on whether it's likely to be effective or if it's a waste of money. We highlight some questionable additive ingredients and feature real customer reviews.","template_suffix":"","handle":"mr-hyde-pre-workout-review","tags":"_related:pre-workout"}

Mr. Hyde Pre-Workout Review: Loaded With Garbage?

Mr. Hyde Pre-Workout Review: Loaded With Garbage?


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Mr. Hyde Pre-Workout is a supplement sold by ProSupps. The brand claims that it can provide “clean energy” to fuel you physically, and also that it increases mental focus and energy.

But does Mr. Hyde Pre-Workout contain research-backed ingredients for improving energy? What about for increasing strength? Does it contain any unhealthy additive ingredients? And how do real users rate and describe the effects of Mr. Hyde Pre-Workout?

In this article we’ll answer all of these questions and more as we analyze the ingredients in Mr. Hyde Pre-Workout based on medical studies to give our take on whether it’s likely to be effective or if it’s a waste of money.

We’ll share our thoughts about whether the supplement is likely to cause side effects, explain why it was recalled in the past, and feature real, unsponsored Mr. Hyde Pre-Workout user reviews.

This supplement contains a wide range of ingredients so we’ll break our ingredient analysis into two sections: active ingredient analysis and inactive ingredient analysis.

Active Ingredient Analysis

Mr. Hyde Pre-Workout active ingredients

The active ingredients in Mr. Hyde Pre-Workout are shown above.

Beta alanine is an effective ingredient that can increase power. A clinical trial published in The Journal of Strength and Conditioning Research found that this ingredient prevented fatigue and increased power in athletes at a 1.2 gram (g) dose, which is less than that in Mr. Hyde.

Creatine can also increase power, but may be underdosed at only 1 g dose. As we documented in our Con Cret Creatine review article, clinical research suggests that the effective maintenance creatine dose is around 2.5 g.

Caffeine is included in almost all pre-workout supplements, and for good reason. A medical review published in the Sports Medicine journal found that it increases power and reduces fatigue. The 169 milligram (mg) dose in Mr. Hyde Pre-Workout is an effective dose.

Nitrosigine and citrulline are shown in a 2020 clinical trial to increase blood flow in young athletes, but at a dose of 1.5 g and 8 g, respectively. The doses in Mr. Hyde are only 500 mg and 500 mg, and we can’t find clinical evidence backing such low doses.

Choline is often included in pre-workout supplements, but we’re not sure why. A medical review published in the Sports Health journal analyzed data from three clinical trials on choline supplementation, and found that there was no significant benefit in any of the three trials.

The remaining active ingredients are included at too low of a dose to have any benefit for exercise performance in our opinion.

Overall, we consider Mr. Hyde likely to improve exercise performance and endurance given its effective dose of caffeine and beta alanine. However, we aren’t particularly impressed with the formulation given that this is two active ingredients that we consider effectively dosed out of 11 total.

But the main reason we recommend avoiding Mr. Hyde Pre-Workout is due to its inactive ingredients, which we’ll examine in the next section.

Inactive Ingredient Analysis

Mr. Hyde inactive ingredients

There are a number of inactive ingredients in this pre-workout powder that we consider questionable from a health perspective.

FD&C Blue #1 is an artificial food dye. A medical review on the toxicology of food dyes reported negative health effects from all currently-approved food dyes.

Artificial flavors were shown in a clinical trial on animals to be toxic.

Sucralose is an artificial sweetener shown to cause negative changes to insulin levels, as we referenced in our review of the Feel Great System

Acesulfame potassium is another artificial sweetener.

Citric acid is commonly derived from a fungus when used in manufacturing, and is clinically shown to cause whole-body inflammation in a small subset of individuals.

Natural flavors is a healthier choice than artificial flavors in our opinion, but there are toxicity concerns regarding some natural flavoring agents in clinical research.

This is one of the longest lists of questionable inactive ingredients in any supplement we’ve reviewed on Illuminate Health. But how do real users describe the supplement’s effects? We’ll review in the next section.

Why Was Mr. Hyde Pre-Workout Recalled?

Mr. Hyde Pre-Workout was recalled in 2016 according to Clark's Nutrition. The recall was apparently due to an unapproved drug ingredient called picamilon being included. 

Picamilon is not allowed for use in dietary supplements according to the FDA, and has lacking safety data.

ProSupps also received a warning letter from the FDA in 2017 for "significant violations" of good manufacturing practice. According to the letter, the manufacturer of Dr. Hyde failed to follow written procedures for the investigation of customer complaints, and failed to establish proper quality control procedures.

This is a red flag about the company as a whole in our opinion.

Real, Unsponsored Mr. Hyde Pre-Workout Reviews

A YouTube fitness creator named “b5lifting” reviewed Mr. Hyde Pre-Workout:

A TikTok fitness influencer named Andrew Burgess gave the pre-workout a mediocre score:

@andrewburgessfit Supplement Reviews Part 1: Mr. Hyde! #gains #fitness #gymlife #preworkout ♬ original sound - Andrew Burgess

Will Mr. Hyde Pre-Workout Cause Side Effects?

Mr. Hyde Pre-Workout doesn’t appear to have been studied in any clinical trials, so it’s impossible to say for certain whether or not it causes side effects. However, we can make an educated guess based on its active ingredients.

Pre-workouts are generally more likely to cause side effects than most supplements due to all of the stimulants they contain.

Caffeine can cause jitteriness and anxiety in those who are caffeine sensitive, though the dose in Mr. Hyde is only around two cups of coffee which probably won’t have a negative effect on most individuals.

Beta alanine has been shown in a 2012 medical review to cause an uncomfortable tingling sensation at the dose included in Mr. Hyde, and this side effect is also reported by a number of individuals online.

Artificial dyes like Blue 1 can cause hyperactivity in some people (especially in children and adolescents) according to the medical review linked in the inactive ingredient section.

We consider Mr. Hyde somewhat likely to cause side effects overall.

Where to Buy Mr. Hyde Pre-Workout for the Best Price

Mr. Hyde Pre-Workout is sold at a variety of online retailers. Here’s the price breakdown at the time of publishing this article:

Brand website: $19.98 (plus $7.95 shipping, link)

Walmart: $19.98 (plus $6.99 shipping, link)

Amazon: $19.98 (free shipping depending on plan – link to official Amazon listing)

Those who can get free shipping on Amazon reduce the overall price by around 25%.

Real Customer Reviews of Mr. Hyde Pre-Workout

Amazon reviews are a more honest source of customer reviews than a brand’s website in our opinion. Mr. Hyde Pre-Workout has an average review rating of 4.4 out of 5 and has been reviewed over 10,000 times on Amazon.

The top positive review from a verified purchaser is written by a user named “Ella” who claims the product is powerful:

“Great workout powder! I only use half of scoop as I feel a full scoop is too much for me but it really helps with my 5am workouts!”

The top negative review from a verified purchaser comes from a user named “Lorenzo Aranda” who’s upset about a recent reduction in the ingredient potency:

“Did anyone else notice the difference in color now? How about the fact that they halved the concentration of the key ingredients for the same price? Sneaky. Essentially it’s just fluff loaded with caffeine.”

Our Clean Pre-Workout Picks

The pre-workout supplement we recommend is Naked Energy by Naked Nutrition.

Like Mr. Hyde, it provides an effective dose of beta alanine and caffeine for power and stamina improvements.

The main difference is that it’s entirely free of questionable additive ingredients like artificial sweeteners and artificial colors. There are no inactive ingredients in this formulation at all, which makes it the healthiest pre-workout formulation on the market in our opinion.

Interested consumers can check out Naked Energy at this link to its product page on the official brand website.

Panax ginseng is clinically shown to reduce mental fatigue (source) and reduce physical fatigue (source). It’s one of the most popular herbal supplements in the world.

Illuminate Labs sells a Panax Ginseng extract supplement for only $15 on a subscription basis which is highly potent (minimum 8% ginsenosides) and is third-party tested to ensure label accuracy and purity. Interested consumers can check out Illuminate Labs Panax Ginseng Extract at this link to the product page on our website.

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Conclusion

Mr. Hyde Pre-Workout is likely to improve workout performance, and it’s sold at a great price. However, the downsides are that the formulation contains a large number of active ingredients that we consider underdosed, and it also has inactive ingredients like artificial flavors and artificial food dye that are questionable from a health perspective.

This pre-workout may cause side effects in individuals who are sensitive to caffeine or stimulants, but so will most pre-workouts.

Amazon currently has the best price on Mr. Hyde Pre-Workout when considering shipping costs.