Neutrogena Hydro Boost is a two-part skincare product that includes a serum and a gel. The brand claims that this duo can provide a “hydrated, healthy glow” and that it “replenishes and smooths skin.”
But does Neutrogena Hydro Boost contain ingredients shown in research studies to moisturize skin? Does the brand use any questionable additives? Which retailer sells Neutrogena Hydro Boost for the best price? And how do real users rate and describe the effects of the product?
In this article we’ll answer all of these questions and more, as we analyze the ingredients in Neutrogena Hydro Boost to give our take on whether or not the two-part system is likely to be effective for hydrating skin, and whether or not it's healthy.
We’ll also provide a cost comparison featuring the retailer that sells Neutrogena Hydro Boost for the best price, and share real customer reviews of the treatment.
Key takeaways:
- Serum contains two preservatives we consider potentially unhealthy
- Gel-Cream contains effective ingredients and no unhealthy preservatives
- We currently recommend Neutrogena Hydro Boost Gel-Cream
Ingredient Analysis – Serum
The ingredients in Neutrogena Hydro Boost Hyaluronic Acid Serum are shown below:
This serum contains a number of research-backed ingredients for hydration and even anti-aging effects.
Hyaluronic acid, from which the product gets its name, was shown in a 2018 medical review to improve the body’s own production of collagen, to hydrate the skin and to have “remarkable anti-wrinkle” effects.
Yeast extract was shown to relieve itch and soothe irritated skin in a clinical trial published in the Journal of Cosmetic Dermatology.
Sodium hyaluronate is the sodium salt of hyaluronic acid, and was shown to have a “positive effect on facial skin health” in a 2023 clinical trial.
Panthenol is a B-vitamin that’s clinically shown to improve skin hydration as we documented in our The Ordinary Hyaluronic Acid review article on another cosmetic product containing this ingredient.
Xylitol can improve skin barrier function and reduce levels of pathogenic bacteria when applied to skin, according to a medical review published in the Nutrients journal.
While there are a number of research-backed ingredients in this serum, there are also two inactive ingredients that may be questionable from a health perspective.
Chlorphenesin is a synthetic preservative that was shown to be toxic to human cells in a 2020 clinical trial.
Phenoxyethanol is another synthetic preservative shown to be toxic to human cells in the same trial.
The above-linked trial is a test tube study, so it’s a weaker standard of evidence than a trial with human participants.
Overall, we consider Neutrogena’s Hydro Boost serum likely to improve skin hydration, improve skin barrier function, and reduce the visible appearance of wrinkles due to its many effective active ingredients.
We don’t currently recommend this product due to the inclusion of the two preservatives referenced above.
Real People Try Hydro Boost
A TikTok creator named “all.things.ar” gives a live product demo and shares her thoughts on Neutrogena Hydro Boost:
@all.things.ar 💧☁️ @Neutrogena #skincare #neutrogena #neutrogenahydroboost #neutrogenahydroboostwatergel #dewyskin #glassskin #skincarereview #skincaretryon #skintok ♬ original sound - all.things.ar
A TikTok creator named “skinswept” has a similarly favorable review:
@skinswept First review in the Gel-Cream Series! #skincare #moisturizer #gelcream @neutrogena_us ♬ original sound - skinswept
Ingredient Analysis – Gel-Cream
The ingredients in Neutrogena Hydro Boost Gel-Cream are shown below:

Like the serum, it does contain some research-backed ingredients.
Sodium hyaluronate was already demonstrated to be effective in the previous Ingredient Analysis section.
Beeswax is clinically shown to have antimicrobial activity, which suggests it may be effective at reducing pathogenic bacteria levels and breakouts, although most of the studies we can find on this ingredient involve naturally-derived beeswax which may be different from the “synthetic beeswax” in this gel.
Glycerin is clinically shown to improve skin moisture content, as we documented in our review of Good Molecules.
Neutrogena has significantly improved the healthiness of this formulation since our initial publication of this review, replacing two preservatives we consider potentially unhealthy (chlorphenesin and phenoxyethanol) with one preservative we consider inert.
We currently recommend Neutrogena Hydro Boost Gel-Cream.
Medical Experts Review Hydro Boost
A dermatologist named Dr. Daniel Sugai compared Neutrogena Hydro Boost with a cheaper alternative which could be considered a dupe, called up & up Hydrating Water Gel:
A doctor named Vanita Rattan shares her thoughts on whether Hydro Boost is a good choice for individuals with darker skin tones:
Where to Get the Best Price
Neutrogena Hydro Boost is sold at a variety of online retailers. Here’s a price breakdown at the time of publishing this article:
Hydro Boost Serum
Ulta: $29.99 (link)
Target: $19.99 (link)
Brand website: $19.99 (plus shipping, link)
Amazon: $16.39 (free shipping depending on plan – link to official Amazon listing)
Hydro Boost Gel-Cream
Ulta: $29.99 (link)
Brand website: $19.99 (link)
Walmart: $15.99 (link)
Amazon: $15.40 (free shipping depending on plan – link to official Amazon listing)
The price of Neutrogena Hydro Boost is currently around 50% cheaper on Amazon compared to Ulta.
Customers Rate Neutrogena Hydro Boost
Amazon is a better resource for honest customer reviews than a brand’s website in our opinion.
The gel-cream version has been reviewed over 46,000 times on Amazon with an average review rating of 4.6 out of 5 stars.
The top positive review from a verified purchaser comes from a user named “Shahzad a.” who likes the smell and product experience:
“Overall, I would definitely recommend Neutrogena Hydro Boost to anyone looking for a moisturizer that's effective, lightweight, and won't make you smell like a 17th-century perfumery. Give it a try – your skin will thank you!”
The top negative review from a verified purchaser is written by an anonymous Amazon customer who dislikes the consistency and claims the product is too small:
“My first disappointment when opening the product was how little there was in the jar. I washed my face as usual and then went to apply. The consistency is very weird, but I expected that since it was described as a gel. Within seconds of applying to my face, my skin began burning. I had to immediately remove and apply my normal moisturizer.”
Our Clean Skincare Pick
Ritual HyaCera is our top anti-aging skin supplement.
It contains wheat oil extract which is clinically shown to "improve skin damages induced by aging."
This product is free of ingredients that we consider to be unhealthy.
Neutrogena Hydro Boost Pros and Cons
Here are the pros and cons of Hydro Boost in our opinion:
Pros:
- Serum formulation is one of the best serums we’ve reviewed
- Both products should improve skin hydration
- Fragrance-free
- Dye-free
- Relatively affordable
- Very favorable customer reviews
- Gel-Cream formulation is substantially improved
Cons:
- Contains two synthetic preservatives
- No mention of clinical testing
- Brand website charges for shipping