URO is a vaginal health supplement sold by a women’s health brand called O POSITIVE. The brand claims that the capsule supplement “supports healthy vaginal odor and pH.”
But can oral supplements really support vaginal health? Does URO contain ingredients shown in clinical trials to improve vaginal health or are these just marketing claims? Does the supplement contain any questionable additive ingredients? And how do real users rate and describe the effects of URO?
In this article we’ll answer all of these questions and more as we analyze the ingredients in URO based on medical studies to give our take on whether the supplement is likely to be effective or if it’s a waste of money.
We’ll also provide a cost breakdown to show which retailer sells URO for the best price, and feature real, unsponsored URO user reviews.
The ingredients in URO are shown above.
While many consumers refer to the product as “URO vitamins,” it’s actually a probiotic supplement rather than a vitamin supplement.
V-Positive Probiotic Blend is the core active ingredient, and it’s a blend of four probiotic species with a total dose of 5 billion colony-forming units (CFU).
Probiotics may be effective for treating and preventing bacterial vaginosis (BV), which can cause negative changes to vaginal odor. A medical review published in the Clinical Microbiology and Infection journal reported the following:
“intra-vaginal administration of Lactobacillus acidophilus for 6-12 days, or oral administration of L. acidophilus or Lactobacillus rhamnosus GR-1 and Lactobacillus fermentum RC-14 for 2 months, resulted in the cure of BV”.
URO contains all three of the probiotic species listed above, so it may be effective against BV.
Lactobacillus reuteri is the fourth probiotic species in URO, and was shown in a 2020 clinical trial to reduce the levels of a pathogenic bacteria in the vagina during pregnancy, and “improve the pregnancy outcome.”
We agree with O POSITIVE’s decision to formulate this supplement with Lactobacillus probiotics, because as described in a 2022 medical review, Lactobacillus is the most abundant probiotic in the vagina, and helps to maintain the low pH of the vagina which prevents growth of harmful bacteria.
Clearly there are a number of potentially effective active ingredients in URO, and the inactive ingredients are safe and non-toxic as well.
Natural color is an additive ingredient that’s derived from edible sources like fruits and vegetables that gives the supplement its pink color. This is a healthier alternative to artificial colors, which may be harmful to human health as discussed in our best probiotic for women article.
We consider URO likely to support optimal vaginal health including pH and odor based on its active ingredients.
But are probiotic supplements for vaginal health OB/GYN approved? We review in the next section.
OB/GYN Explains if Probiotic Vaginal Supplements are Useful
A gynecologist was featured in a video on the popular “The Doctors” YouTube channel, discussing the potential benefits and downsides of probiotic supplements for the vagina.
The video has over 80,000 views and is under two minutes long:
Where to Buy URO for the Best Price
URO only appears to be sold on the brand’s website and Amazon. Here’s a price breakdown at the time of publishing this article:
Brand website: $31.99 (plus shipping)
Amazon: $31.99 (free shipping – link to official Amazon listing)
Shipping cost was $4.99 with the test address we input on URO’s site, so ordering on Amazon may save 13% for consumers interested in a one-time order.
But how do real users rate and describe the effects of the supplement? We’ll review in the next section.
Real, Unsponsored URO User Reviews
A TikTok creator named “Angelaaaaaaaa” shared her experience after using URO:
@jaysmama0220 Parttttt 2 URO review #QuakerPregrain #fyp #uro #freshandclean ♬ original sound - Angelaaaaaaaa
A YouTube creator named “Fit Healthy Momma” published a review of the supplement with over 8,000 views:
Real Customers Review URO
Amazon is a better resource for honest customer reviews than a brand’s website in our opinion.
URO has been reviewed over 1,500 times on Amazon, with an average review rating of 4.5 out of 5 stars.
The top positive review from a verified purchaser comes from a user named “Reewantae” who claims that the supplement helped with chronic BV:
“...within three days of taking these pills, my odor disappeared. Not gonna lie, my vagina was struggling a little because then I started feeling some mild itching at random, but even that eventually stopped within less than thirty days of taking the URO. I honestly haven't smelled this good or felt this great in awhile”
The top negative review from a verified purchaser is written by a user named “Jacki” who claims the supplement causes side effects:
“My daughter and I took two when we got this package with a sandwich and ginger ale. Not even twenty minutes after taking this medication we were vomiting sweating and severe diarrhea to the point that you had exactly nothing left in you…we also took some Pepto-Bismol along with it to try to keep it down in the coat our stomach. This was beyond sad. Because we are still violently vomiting and confined it to a commode and as fast as we put water in is coming right back out so please beware one taking this vitamin”
Our Research-Backed Vaginal Health Picks
While we’re impressed by the formulation of URO, Future Kind Vegan Probiotics is our top pick for a vaginal health supplement.
It provides 30 billion CFU of probiotics total (versus the 5 in URO), five different species of Lactobacillus probiotics (versus the 4 in URO), and also contains three different species of Bifidobacterium probiotics.
A medical review published in the Anaerobe journal suggests that Bifidobacterium probiotics may be as important for vaginal health as Lactobacillus:
“These findings demonstrate that Bifidobacterium is the dominant member of some vaginal microbiomes and suggest that bifidobacteria have the potential to be as protective as lactobacilli”
Interested consumers can check out Future Kind Vegan Probiotics at this link to the official brand’s website. They only cost $29.99 at the time of publishing this article.
Pros and Cons of URO
Here are the pros and cons of URO in our opinion:
- Contains research-backed probiotics for vaginal health
- No unhealthy additive ingredients
- Affordable for a specialty supplement
- Mostly positive online customer reviews
- Unlikely to cause side effects
- Doesn’t appear clinically tested
- Brand fails to describe natural colorant compound
- May not be necessary for those with a healthy vagina