Supergut Review: Is "Nature's Ozempic" Real?

Supergut Review: Is "Nature's Ozempic" Real?

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Supergut is one of the fastest-growing gut health supplements in the US. The company describes prebiotics as "Nature's Ozempic," and sells both prebiotic powders and prebiotic bars.

But does prebiotic supplementation actually cause weight loss, or is this just a marketing claim? Are Supergut's supplements healthy? Do they contain any questionable additives? And how do real users rate and describe the effects of Supergut?

In this article we'll answer all of these questions and more, as we analyze clinical research on prebiotic supplementation to determine if it can cause weight loss, and if so, how much.

We'll also analyze the ingredients in Supergut's most popular supplements to give our take on whether or not they're healthy, and feature unsponsored customer reviews.

Do Prebiotics Cause Weight Loss?

The association between prebiotic supplementation and weight loss has been studied in clinical trials.

A 2022 medical review on fiber supplementation in overweight and obese individuals concluded the following:

"The participants with dietary fibre supplementation showed a significantly higher reduction in body weight."

Average weight loss in all surveyed trials was around three pounds, but most of the trials were only around 12 weeks long.

A clinical study published in The Journal of Nutrition reported that fiber intake predicted dietary weight loss in adults. The more fiber consumed, the greater the weight loss.

It's also worth noting that our ancestors consumed significantly more fiber than humans in developed nations, as we documented in our do fiber gummies work article.

Based on the available research, we consider prebiotic fiber supplementation likely to cause weight loss.

Is Supergut Healthy or Unhealthy?

Supergut sells a variety of fiber products.

We consider the unflavored fiber powder to be healthy, and the flavored shakes to be somewhat less healthy. We'll explain why below.

The ingredients in Supergut's Chocolate Shake are shown below:

Supergut Chocolate Shake ingredients

While this shake does contain a healthy 15 grams (g) of fiber, which may support weight loss, it also contains a number of additive ingredients that may be questionable from a health perspective.

Natural flavor is a broad, categorical descriptor that fails to describe the specific flavoring chemicals used. 

Natural flavor may include chemicals such as preservatives, according to a 2009 medical review.

Vitamin and mineral blend contains a large number of synthetic vitamin additives. We haven't come across any clinical evidence that supplemental vitamins and minerals are beneficial to health in individuals without a deficiency in those vitamins and minerals, and we don't understand the inclusion of this blend in a prebiotic shake.

Folic acid is one of the vitamins in the blend, and is clinically shown to be associated with a slightly increased risk of prostate cancer when supplemented.

The ingredients in Supergut's Prebiotic Mix (The Gut Healthy Prebiotic Shake) are shown below:

Supergut Prebiotic Mix ingredients

A blend of resistant starch prebiotic fibers is the only ingredient in this formulation. There are no questionable additives.

Resistant starch intake is clinically shown to support optimal gut health, as we documented in our Standard Process reviews article.

From a formulation perspective, we recommend Supergut Fiber Mix and consider it likely to support optimal gut health.

Real People Try Supergut

A TikTok creator named "katiakaterinaaa" claims to have experienced gut health benefits from Supergut:

@katiakaterinaaa so in love with this product actually, definitely recommend, your gut needs it more than you know! 😊 #supergutpartner #guthealth #gettingregular #digestivehealth ♬ Escapism. - Super Sped Up - RAYE

A TikTok creator named Chelsea Thompson claims that Supergut's shake has a satiating effect:

@chelsea.t_ So obsessed with this product! #supergut #guthealth #grwm #ootd #hotgirlwalk #protein #healthy #fitness @Supergut #PepsiApplePieChallenge ♬ FEEL THE GROOVE - Queens Road, Fabian Graetz

Our Clean Gut Health Picks

MBG Organic Fiber Potency+ is our top fiber pick.

MBG Organic Fiber Potency+ contains 100% soluble fiber, which was described as "one of the most important nutrients for the gut microbiota" in a clinical review published in the Molecules journal.

Ritual Synbiotic+ is our top value probiotic pick.

It contains prebiotics, probiotics and postbiotics, and costs under $1.50 per serving at the time of updating this article.

Probiotics "can improve in the immune, systems in healthy adults" according to a 2019 medical review.

VSL#3 is our top premium probiotic pick.

This probiotic supplement has been studied in 25 clinical trials, and a 2020 meta-study on VSL#3 concluded the following:

"...many studies demonstrated that VSL#3 has a beneficial effect on obesity and diabetes, allergic diseases, nervous systemic diseases, AS, bone diseases, and female reproductive systemic diseases."

All of the products recommended in this section are entirely free of ingredients that we consider to be unhealthy.

Customers Rate Supergut

Amazon is a better resource for unbiased customer reviews in our opinion.

Supergut's most-reviewed product on Amazon is their Prebiotic Mix, which has been reviewed over 150 times and has an average review rating of 3.9 out of 5 stars at the time of publishing this article.

A top positive review from a verified purchaser comes from a user named "coffeemom78" who gave the product a 5/5 rating, and claims it improves satiation:

"Overall, I feel like I have been more full longer and I struggle less with bloating and stomach issues which is the reason I bought this. I crave less sugar as well, which is a bonus. I have been using this for 16 straight days and say it continues to work."

A top negative review from a verified purchaser is written by a user named "jaime" who gave the product a 1/5 star rating, and claims it caused constipation:

"I was so excited to try this! Sadly the first time using it, it totally stopped me up. Kind of the opposite of what you are needing it to do, if you are buying it."

Can You Heal the Gut Naturally?

A YouTube creator named Meghan Livingstone has a video on healing the gut naturally that has over 360,000 views:

Supergut Pros and Cons

Here are the pros and cons of Supergut in our opinion:


  • Resistant starch can support optimal gut health
  • Fiber supplementation can cause weight loss
  • Prebiotic Mix supplement has a healthy formulation
  • Great branding


  • Shakes and bars contain natural flavor
  • Shakes contain a large number of added vitamins and minerals
  • Relatively expensive per-serving
Stay up-to-date on our research reviews


Supergut's unflavored prebiotic mix is one of the healthiest fiber supplements we've reviewed to date on Illuminate Health.

This supplement contains resistant starch, which may have uniquely positive benefits on gut health compared to other types of prebiotics.

We don't consider Supergut's shakes and bars to be as healthy, because they have a large number of additive ingredients like natural flavor and synthetic vitamins.

There is a significant amount of clinical research showing that fiber supplementation can cause weight loss, so we have no problem with Supergut's "Nature's Ozempic" marketing catchphrase.

We came across a large number of positive reviews of Supergut on TikTok while researching this article.