Nugenix Thermo Review: Do Fat Burning Pills Really Work?

Nugenix Thermo Review: Do Fat Burning Pills Really Work?

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Nugenix Thermo is a weight loss supplement. Its manufacturer claims that it’s effective because it can “promote thermogenesis,” which means that it can increase core body temperature and energy expenditure at rest. We reviewed Nugenix supplements very unfavorably in our overall review of the brand, but Thermo is a new supplement sold by the brand that we’re choosing to review individually.

Can a dietary supplement really increase core body temperature? Are the ingredients proven in medical research to be effective? Does Nugenix Thermo contain any questionable additive ingredients? And how do real customers review the supplement?

In this article we’ll answer all of these questions and more as we review every ingredient in Nugenix Thermo and share some real customer reviews.

Ingredient Review

Nugenix Thermo ingredients

Nugenix Thermo contains a large number of active ingredients.

Caffeine intake, specifically high caffeine intake, is associated with weight loss in medical research. However the dose in Nugenix Thermo is relatively low at 150 milligrams (mg) which is equivalent to around 1.5 cups of coffee. We cannot identify any studies showing this low of a dose causes weight loss, nor does Nugenix cite any, so we’ll consider this ingredient ineffective.

Morosil is an effective weight loss ingredient. It’s a patented extract of the blood orange fruit, and a clinical trial published in the Natural Product Research journal found it to cause 6.79 pounds of average weight loss over 12 weeks. The dose used was the exact same dose as in Nugenix Thermo.

Green coffee extract does appear to cause weight loss in clinical research, but we consider the 75 mg in this supplement to be underdosed. A 2011 medical review found that this ingredient caused a small but statistically significant amount of weight loss, but the doses used in every clinical trial reviewed were more than twice as much as in Nugenix Thermo.

Capsimax is a patented cayenne pepper extract that’s effectively-dosed in Nugenix Thermo. As we documented in our review of weight loss supplement PhenQ, 100 mg of this ingredient is proven in clinical research to cause weight loss.

Nugenix Thermo contains three other ingredients that we consider effective for weight loss but are underdosed in this formulation: guarana extract, green tea extract and Carnipure.

While there are a number of effective ingredients in this supplement, there are several that we recommend consumers avoid.

Green tea extract may cause liver injury in a small subset of patients as reported by Health Canada. We do not consider this likely given the relatively low dose of green tea extract in Nugenix Thermo, however we recommend avoiding this ingredient entirely to be safe.

Nugenix Thermo also contains a vitamin and mineral blend of vitamin C, niacin and chromium. We recommend avoiding dietary supplements with added vitamins and minerals, because it seems illogical to take supplemental vitamins and minerals without proof of a deficiency. Individuals taking vitamins and minerals starting with normal blood levels of those nutrients may end up with blood levels that are too high.

Overall we consider Nugenix Thermo likely to be effective for weight loss, and we consider it to have an impressive formulation compared to most weight loss supplements. It contains multiple effectively-dosed ingredients, and no potentially harmful inactive ingredients like artificial dye or artificial sweetener.

We don’t recommend this supplement overall due to the green tea extract and vitamin and mineral additives, but we consider it an above-average weight loss supplement.

Does Nugenix Thermo Cause Side Effects?

Consumers are often curious if Nugenix Thermo is likely to cause side effects, which is a reasonable concern given that many weight loss supplements contain stimulant ingredients.

Nugenix Thermo has never been studied in a clinical trial that evaluated side effects, so there is no way to determine for sure, but based on the active ingredients we consider this supplement unlikely to cause any significant side effects.

Caffeine is stimulatory but the dose is relatively low in this supplement. Individuals sensitive to caffeine may want to avoid this supplement. 

Other than caffeine, we cannot identify any ingredients we consider likely to cause any side effects at all.

Can Supplements Actually Promote Thermogenesis?

As detailed in the intro section of this article, Nugenix claims that this supplement promotes thermogenesis and increases body temperature. Whether or not this is truly possible is discussed in an informative podcast published by a YouTube channel called “Body Science.”

The video has achieved over 50,000 views at the time of writing this article, and features a guest who’s a PhD and a nutritionist:

Where to Get the Best Price

Nugenix Thermo is sold at a variety of online retailers. Here's a price breakdown at the time of publishing this article:

Brand website: $59.99 (plus shipping, link)

GNC: $59.99 (free shipping, link)

Walmart: $49.99 (free shippinglink)

Amazon: $49.99 (free shipping, link to official Amazon listing)

Nugenix is currently around 20% cheaper on Amazon and Walmart than the brand's website when factoring in shipping fees.

Nugenix Thermo Customer Reviews

Nugenix Thermo is sold on Amazon which is a more objective resource for customer reviews than a brand’s website in our opinion. The product has been reviewed over 2,900 times and currently has an average review rating of 4 out of 5 stars.

The top positive review from a verified purchaser is written by a user named “BK-One” who claims that the product has caused weight loss without any side effects:

“I am 5 lbs. lighter than I was over 48 hours ago. Maybe it's the product, maybe it's the change in the habits the past 2 days or maybe it's both. Either way, it's a win for me…The pills have not made me feel jitters or extra alert to where I can't sleep or anything. Basically, no side effects and usually by now, there are some.”

The top negative review from a verified purchaser comes from a user named “brent fong” who claims that the product caused uncomfortable side effects:

“I feel this product may be unsafe for some people. I took just one capsule and I got sick. I felt like I was overheating; was just hot all over. That may be what this product is supposed to do, when your metabolism speeds up. So, I can accept that aspect of the product. However, I also felt just slightly nauseous and had a slight headache. Furthermore, I just had a general feeling of discomfort. Perhaps my body is supposed to get used to these side effects and will no longer be problematic with continued use; but I just felt too uncomfortable to want to try to tough it out.”

Our Clean Weight Loss Picks

There are food-based nutrients which have been shown in medical studies to be effective for weight loss.

Dietary fiber was shown in a medical review published in The Journal of Nutrition to cause 16 pounds of weight loss in 6 months when combined with moderate caloric restriction (750 calories per day below baseline).

MBG Organic Fiber Potency+ is our top fiber pick because it's certified organic, provides 7 g of fiber per serving and costs under $1.85 per serving at the time of updating this article.

MCT oil was shown in a meta-study to cause more than one pound of weight loss over 10 weeks. This equates to potential annualized weight loss of 6 pounds per year with less than one tablespoon's worth of MCT oil per day.

Bulletproof MCT Oil is our top MCT oil product, because the only ingredient is MCT oil derived from coconuts. and it currently costs only $15.50 for over a month's worth of product.

Ginger intake "significantly decreased body weight" according to a 2019 meta-study on ginger and weight loss that analyzed data from 14 clinical trials.

Pique La Ginger is our top ginger product, because it's an organic tea in convenient crystallized form, and all that's needed is to pour the powder into a glass and add hot water.

All three of the products mentioned in this section are entirely free of additive ingredients that we consider to be unhealthy.

Stay up-to-date on our research reviews


Nugenix Thermo is the best-formulated Nugenix supplement that we’ve reviewed on Illuminate Health. It contains multiple ingredients that we consider effectively dosed for weight loss, and we do believe that the product is likely to cause weight loss.

That being said, we do not recommend the supplement overall due to the inclusion of green tea extract and added vitamins and minerals, which are ingredients we recommend consumers avoid.

Nugenix has somewhat negative customer reviews overall.