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{"id":556736872521,"title":"Midol Ingredient Review: Can an OTC Drug Treat PMS?","created_at":"2022-07-12T23:52:08-04:00","body_html":"\u003cscript type=\"application\/ld+json\"\u003e\/\/ \u003c![CDATA[\n{\n \"@context\": \"https:\/\/schema.org\",\n \"@type\": \"Article\",\n \"headline\": \"Midol Ingredient Review: Can an OTC Drug Treat PMS?\",\n \"keywords\": \"midol ingredients, can men take midol, midol complete, ingredients in midol, whats in midol, midol active ingredients\",\n \"description\": \"Our research team reviews the ingredients in Midol to determine if it's likely to be safe and effective for treating PMS. We highlight inactive ingredients that we consider questionable from a health perspective, and answer whether men can use Midol too.\",\n \"url\": \"https:\/\/illuminatelabs.org\/blogs\/health\/midol-ingredients\",\n\"author\": {\n \"@type\": \"Person\",\n \"name\": \"Calloway Cook\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/calloway-cook\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/calloway-cook\/\",\n \"jobTitle\": \"President\",\n \"knowsAbout\": \"entrepreneurship, dietary supplements, herbal supplements, eCommerce, medical research\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": \"S.I. Newhouse School of Public Communications at Syracuse University\"\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"creator\": {\n \"@type\": \"Person\",\n \"name\": \"Calloway Cook\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/calloway-cook\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/calloway-cook\/\",\n \"jobTitle\": \"President\",\n \"knowsAbout\": \"entrepreneurship, dietary supplements, herbal supplements, eCommerce, medical research\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": \"S.I. Newhouse School of Public Communications at Syracuse University\"\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"editor\": {\n \"@type\": \"Person\",\n \"name\": \"Taylor Graber MD\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/taylor-graber\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/taylor-j-graber-md-81351642\/\",\n \"jobTitle\": \"Content Partner\",\n \"knowsAbout\": \"medicine, health, anesthesiology, iv therapy, science, drugs, pharmaceutical, medical research, scientific research, medical journals, entrepreneurship, healthcare, orthopedic surgery, biomedical engineering\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"University of California San Diego\",\n \"Arizona University\",\n \"University of Arizona College of Medicine\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"image\": {\n\"@type\": \"ImageObject\",\n\"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Midol_Ingredients_Thumbnail.png?v=1657684933\",\n\"width\": \"3860\",\n\"height\": \"3860\"\n},\n\"citation\": [\n\"https:\/\/illuminatelabs.org\/blogs\/health\/dayquil-ingredients\", \n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9194998\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27813503\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23026007\/\",\n\"https:\/\/www.efsa.europa.eu\/en\/news\/titanium-dioxide-e171-no-longer-considered-safe-when-used-food-additive\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22069417\/\",\n\"https:\/\/www.midol.com\/frequently-asked-questions\"\n],\n\"mentions\": [{\n \"@type\": \"Thing\",\n \"name\": \"Bayer\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"acetaminophen\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"caffeine\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"artificial food dye\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"magnesium\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"Vitamin B6\"\n }\n],\n\"datePublished\": \"2022-07-12\",\n\"copyrightHolder\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n},\n\"publisher\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\",\n \"url\": \"https:\/\/illuminatelabs.org\/\",\n \"description\": \"Illuminate Labs is the most transparent supplement company in the U.S., and is a leading publisher of research-based health information.\",\n \"knowsAbout\": \"supplements, science, nutrition, exercise, health, medication, pharmaceutical, wellness, diet, weight loss, medical research\",\n \"publishingPrinciples\": \"https:\/\/illuminatelabs.org\/pages\/editorial-guidelines\",\n \"logo\": {\n \"@type\": \"ImageObject\",\n \"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Illuminate_Labs_Logo.png?v=1641249064\", \n \"width\": 150,\n \"height\": 150\n},\n \"foundingDate\": \"2019-01-30\",\n \"Address\": {\n \"@type\": \"PostalAddress\",\n \"streetAddress\": \"50 Union Street, Unit 9\",\n \"addressLocality\": \"Northampton\",\n \"addressRegion\": \"Massachusetts\",\n \"postalCode\": \"01060\",\n \"addressCountry\": \"US\"\n},\n \"sameAs\": [\n \"https:\/\/www.instagram.com\/illuminatelabs\",\n \"https:\/\/twitter.com\/illuminatelabs\",\n \"https:\/\/www.linkedin.com\/company\/illuminate-labs-supplements\",\n \"https:\/\/www.youtube.com\/channel\/UCpgSJAsIPb-fZ25djtTxBEA\"\n ]\n }\n}\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003cp\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Midol_Ingredients_Article_Header_Image_Optimized.png?v=1657684706\" alt=\"\"\u003e\u003c\/span\u003e\u003c\/i\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eDisclaimer: None of the information in this article constitutes medical advice, and is just the opinion of the writer(s) and published for informational purposes only. We recommend that patients follow their doctor’s guidance in regard to over-the-counter (OTC) medication.\u003c\/span\u003e\u003c\/i\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cspan class=\"dc\"\u003eM\u003c\/span\u003eidol is a popular OTC medication that claims to relieve period symptoms such as cramps, bloating and fatigue. It’s manufactured and sold by Bayer, which is one of the largest international pharmaceutical companies.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMany consumers turn to Midol when they’re experiencing uncomfortable period symptoms, but are its ingredients actually proven to work based on medical research? Are there any questionable additives in the product?\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThese are the questions we’ll seek to answer in this article.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eMidol Complete Active Ingredient Review\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Midol_Complete_Active_Ingredients_Optimized.png?v=1657684751\" alt=\"Midol Complete active ingredients list\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe standard Midol product is called “Midol Complete” and claims to provide 6 hours of symptom relief. It contains three active ingredients.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe first active ingredient, \u003c\/span\u003e\u003cb\u003eacetaminophen\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e, is a pain reliever that’s common in many OTC drugs. As we documented in our recent \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/dayquil-ingredients\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eDayQuil ingredients\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e article, of another brand containing this ingredient, acetaminophen is backed by significant medical research. It’s proven in medical trials to reduce pain significantly. We consider this an effective ingredient for pain relief.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCaffeine\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is the second active ingredient, at a dosage of 60 milligrams (mg). This is around two-thirds of the caffeine content in a standard cup of coffee.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eBayer doesn’t seem to explicitly state why caffeine is included. The manufacturer notes that caffeine is a diuretic, so presumably it’s included to reduce water-weight gain. A \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9194998\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in the \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eAnnals of Nutrition and Metabolism\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e medical journal found that coffee intake was associated with greater reductions in water weight short-term. Coffee, and by proxy caffeine, increased fluid excretion.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThis suggests that coffee is an effective diuretic, but we can’t find any medical research suggesting that caffeine is effective for bloating.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePyrilamine maleate\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is the final active ingredient, and is an antihistamine. This ingredient appears to be particularly effective for treating premenstrual syndrome (PMS)-related pain according to \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27813503\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical research\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e, so we find it to be a high-quality ingredient inclusion. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAntihistamines may also reduce other symptoms of PMS such as headache and fatigue.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOverall we consider this to be a well-formulated drug that’s likely to reduce the severity of period symptoms and provide relief. We cannot locate much medical research suggesting that this product is effective for bloating, but there does appear to be demonstrated efficacy for the other health claims.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eMidol Complete Inactive Ingredient Review\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Midol_Complete_Inactive_Ingredients_Optimized.png?v=1657684770\" alt=\"Midol Complete inactive ingredients list\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMidol Complete contains two inactive ingredients that we recommend consumers avoid.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe first is \u003c\/span\u003e\u003cb\u003eFD\u0026amp;C Blue #2\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e, which is an artificial food dye. As we’ve mentioned in many of our articles, we recommend that people avoid artificial food dyes as much as possible as they provide no nutritional benefits and may be harmful to human health. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23026007\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e of the toxicology of food dyes, published in the \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eInternational Journal of Occupational Medicine and Environmental Health\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e, concluded the following: “The inadequacy of much of the testing and the evidence for carcinogenicity, genotoxicity, and hypersensitivity…indicates that all of the currently used dyes should be removed from the food supply and replaced, if at all, by safer colorings.”\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThis product also contains titanium dioxide which \u003c\/span\u003e\u003ca href=\"https:\/\/www.efsa.europa.eu\/en\/news\/titanium-dioxide-e171-no-longer-considered-safe-when-used-food-additive\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eis banned\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e in the European Union (E.U.) for use as a food additive due to toxicity concerns. The E.U. has much better consumer protections than the U.S.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe would not recommend this product due to the inclusion of these additive ingredients.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eBetter Alternative\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe recommend that patients speak with their doctor about taking magnesium and Vitamin B6 to naturally reduce PMS symptoms.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22069417\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e found that this combination decreased PMS scores on average. It’s unclear whether this is because patients suffering from PMS have lower levels of these nutrients or whether they have other biological effects, but we consider this combination to be a relatively safe and natural treatment that’s free of additives like artificial dye.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe dosages used in the trial were 250 mg of magnesium and 40 mg of Vitamin B6.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe’re not suggesting that this treatment will be as effective as Midol; we just consider it to be a healthier option and likely to be at least somewhat effective for most patients.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eCan Men Take Midol?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eBecause Midol treats a number of discomforting symptoms like bloating and headache that either sex can experience, male consumers are often curious if they can take this OTC drug to relieve those same symptoms.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAccording to Midol’s \u003c\/span\u003e\u003ca href=\"https:\/\/www.midol.com\/frequently-asked-questions\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eFAQ page\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e, it’s safe for men to take Midol if they’re experiencing similar symptoms to women with PMS. The brand notes that the formulation was created specifically for women.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWhile we don’t believe that Midol is likely to be harmful to men, we wouldn’t recommend that men take this drug because there are other options to treat headache and bloating that aren’t formulated specifically for painful periods, and are free of artificial dye and titanium dioxide.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eConclusion\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMidol is likely to reduce symptoms of PMS. It’s formulated with active pharmaceutical ingredients which are proven in research to relieve pain and other symptoms of PMS.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMidol Complete contains additive ingredients like artificial dye and titanium dioxide which we recommend avoiding due to toxicity concerns.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe recommend that patients speak with their doctor about the combination of magnesium and Vitamin B6 supplementation for relieving PMS symptoms, as this combination was found effective in clinical research and is unlikely to cause any side effects or health risks.\u003c\/span\u003e\u003c\/p\u003e","blog_id":49281925193,"author":"Calloway Cook","user_id":26601750601,"published_at":"2022-07-12T23:59:45-04:00","updated_at":"2022-08-18T23:49:48-04:00","summary_html":"We review the ingredients in Midol to determine if it's likely to be safe and effective for treating PMS. We highlight inactive ingredients that we consider questionable from a health perspective, and answer whether men can use Midol too.","template_suffix":"","handle":"midol-ingredients","tags":"_related:PMS"}

Midol Ingredient Review: Can an OTC Drug Treat PMS?

Midol Ingredient Review: Can an OTC Drug Treat PMS?


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Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.
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Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.


Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.

Disclaimer: None of the information in this article constitutes medical advice, and is just the opinion of the writer(s) and published for informational purposes only. We recommend that patients follow their doctor’s guidance in regard to over-the-counter (OTC) medication.

Midol is a popular OTC medication that claims to relieve period symptoms such as cramps, bloating and fatigue. It’s manufactured and sold by Bayer, which is one of the largest international pharmaceutical companies.

Many consumers turn to Midol when they’re experiencing uncomfortable period symptoms, but are its ingredients actually proven to work based on medical research? Are there any questionable additives in the product?

These are the questions we’ll seek to answer in this article.

Midol Complete Active Ingredient Review

Midol Complete active ingredients list

The standard Midol product is called “Midol Complete” and claims to provide 6 hours of symptom relief. It contains three active ingredients.

The first active ingredient, acetaminophen, is a pain reliever that’s common in many OTC drugs. As we documented in our recent DayQuil ingredients article, of another brand containing this ingredient, acetaminophen is backed by significant medical research. It’s proven in medical trials to reduce pain significantly. We consider this an effective ingredient for pain relief.

Caffeine is the second active ingredient, at a dosage of 60 milligrams (mg). This is around two-thirds of the caffeine content in a standard cup of coffee.

Bayer doesn’t seem to explicitly state why caffeine is included. The manufacturer notes that caffeine is a diuretic, so presumably it’s included to reduce water-weight gain. A clinical trial published in the Annals of Nutrition and Metabolism medical journal found that coffee intake was associated with greater reductions in water weight short-term. Coffee, and by proxy caffeine, increased fluid excretion.

This suggests that coffee is an effective diuretic, but we can’t find any medical research suggesting that caffeine is effective for bloating.

Pyrilamine maleate is the final active ingredient, and is an antihistamine. This ingredient appears to be particularly effective for treating premenstrual syndrome (PMS)-related pain according to medical research, so we find it to be a high-quality ingredient inclusion. 

Antihistamines may also reduce other symptoms of PMS such as headache and fatigue.

Overall we consider this to be a well-formulated drug that’s likely to reduce the severity of period symptoms and provide relief. We cannot locate much medical research suggesting that this product is effective for bloating, but there does appear to be demonstrated efficacy for the other health claims.

Midol Complete Inactive Ingredient Review

Midol Complete inactive ingredients list

Midol Complete contains two inactive ingredients that we recommend consumers avoid.

The first is FD&C Blue #2, which is an artificial food dye. As we’ve mentioned in many of our articles, we recommend that people avoid artificial food dyes as much as possible as they provide no nutritional benefits and may be harmful to human health. 

A medical review of the toxicology of food dyes, published in the International Journal of Occupational Medicine and Environmental Health, concluded the following: “The inadequacy of much of the testing and the evidence for carcinogenicity, genotoxicity, and hypersensitivity…indicates that all of the currently used dyes should be removed from the food supply and replaced, if at all, by safer colorings.”

This product also contains titanium dioxide which is banned in the European Union (E.U.) for use as a food additive due to toxicity concerns. The E.U. has much better consumer protections than the U.S.

We would not recommend this product due to the inclusion of these additive ingredients.

Better Alternative

We recommend that patients speak with their doctor about taking magnesium and Vitamin B6 to naturally reduce PMS symptoms.

A clinical trial found that this combination decreased PMS scores on average. It’s unclear whether this is because patients suffering from PMS have lower levels of these nutrients or whether they have other biological effects, but we consider this combination to be a relatively safe and natural treatment that’s free of additives like artificial dye.

The dosages used in the trial were 250 mg of magnesium and 40 mg of Vitamin B6.

We’re not suggesting that this treatment will be as effective as Midol; we just consider it to be a healthier option and likely to be at least somewhat effective for most patients.

Can Men Take Midol?

Because Midol treats a number of discomforting symptoms like bloating and headache that either sex can experience, male consumers are often curious if they can take this OTC drug to relieve those same symptoms.

According to Midol’s FAQ page, it’s safe for men to take Midol if they’re experiencing similar symptoms to women with PMS. The brand notes that the formulation was created specifically for women.

While we don’t believe that Midol is likely to be harmful to men, we wouldn’t recommend that men take this drug because there are other options to treat headache and bloating that aren’t formulated specifically for painful periods, and are free of artificial dye and titanium dioxide.

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Conclusion

Midol is likely to reduce symptoms of PMS. It’s formulated with active pharmaceutical ingredients which are proven in research to relieve pain and other symptoms of PMS.

Midol Complete contains additive ingredients like artificial dye and titanium dioxide which we recommend avoiding due to toxicity concerns.

We recommend that patients speak with their doctor about the combination of magnesium and Vitamin B6 supplementation for relieving PMS symptoms, as this combination was found effective in clinical research and is unlikely to cause any side effects or health risks.





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