{"id":675748708658,"title":"Zepbound Review: The New \u0026 Improved Ozempic?","created_at":"2024-03-30T15:17:15-04:00","body_html":"\u003cscript type=\"application\/ld+json\"\u003e\/\/ \u003c![CDATA[\n{\n \"@context\": \"https:\/\/schema.org\",\n \"@type\": \"Article\",\n \"headline\": \"Zepbound Review: The New \u0026 Improved Ozempic?\",\n \"keywords\": \"zepbound, zepbound reviews, zepbound review, zepbound cost, zepbound vs wegovy, zepbound vs mounjaro, zepbound side effects, zepbound weight loss drug\",\n \"description\": \"Our research team analyzes clinical studies on Zepbound to give our take on whether or not it's likely to cause weight loss, and if so, how much. We compare Zepbound to other injectable weight loss drugs like Wegovy, and feature unsponsored patient reviews.\",\n \"url\": \"https:\/\/illuminatelabs.org\/blogs\/health\/zepbound-review\",\n\"author\": \n {\n \"@type\": \"Person\",\n \"name\": \"Calloway Cook\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/calloway-cook\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/calloway-cook\/\",\n \"jobTitle\": \"President\",\n \"knowsAbout\": \"entrepreneurship, dietary supplements, herbal supplements, eCommerce, medical research\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": \"S.I. Newhouse School of Public Communications at Syracuse University\"\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n },\n\"editor\": {\n \"@type\": \"Person\",\n \"name\": \"Auren Weinberg\",\n \"honorificSuffix\": \"M.D.\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/auren-weinberg\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/aurenweinberg\/\",\n \"jobTitle\": \"Medical Reviewer\",\n \"knowsAbout\": \"pharmaceutical medication, medicine, OTC drugs, medical research, clinical trials, generic drugs, branded drugs, dietary supplements, chemistry, health, wellness, healthcare\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"Haverford College\",\n \"University of Rochester School of Medicine and Dentistry\",\n \"Fox School of Business at Temple University\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"image\": {\n\"@type\": \"ImageObject\",\n\"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Zepbound_Thumbnail.png?v=1711855710\",\n\"width\": \"3036\",\n\"height\": \"3036\"\n},\n\"citation\": [\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35658024\/\", \n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37840095\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37344384\/\",\n\"https:\/\/illuminatelabs.org\/blogs\/health\/mounjaro-weight-loss\",\n\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2023\/217806s000lbl.pdf\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/pmid\/36789109\/\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6768815\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25636220\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29393665\/\",\n\"https:\/\/www.drugs.com\/comments\/tirzepatide\/zepbound.html\",\n\"https:\/\/illuminatelabs.org\/blogs\/health\/orlistat-review\",\n\"https:\/\/www.goodrx.com\/zepbound\",\n\"https:\/\/zepbound.lilly.com\/coverage-savings\"\n],\n\"mentions\": [{\n \"@type\": \"Organization\",\n \"name\": \"FDA\"\n },\n {\n \"@type\": \"Brand\",\n \"name\": \"Wegovy\"\n },\n {\n \"@type\": \"Brand\",\n \"name\": \"Mounjaro\"\n },\n {\n \"@type\": \"Brand\",\n \"name\": \"Drugs.com\"\n },\n {\n \"@type\": \"Brand\",\n \"name\": \"Dr. Dan\"\n },\n {\n \"@type\": \"Brand\",\n \"name\": \"GoodRx\"\n }\n],\n\"datePublished\": \"2024-03-30\",\n\"copyrightHolder\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n},\n\"publisher\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\",\n \"url\": \"https:\/\/illuminatelabs.org\/\",\n \"description\": \"Illuminate Labs is the most transparent supplement company in the U.S., and is a leading publisher of research-based health information.\",\n \"knowsAbout\": \"supplements, science, nutrition, exercise, health, medication, pharmaceutical, wellness, diet, weight loss, medical research\",\n \"publishingPrinciples\": \"https:\/\/illuminatelabs.org\/pages\/editorial-guidelines\",\n \"memberOf\": [\n {\n \"@type\": \"Organization\",\n \"name\": \"U.S. Chamber of Commerce\",\n \"url\": \"https:\/\/www.uschamber.com\/\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Certified B Corp\",\n \"url\": \"https:\/\/www.bcorporation.net\/en-us\/\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Natural Products Association\",\n \"url\": \"https:\/\/www.npanational.org\/\"\n }\n ], \n \"logo\": {\n \"@type\": \"ImageObject\",\n \"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Illuminate_Labs_Favicon_48x48_7595c3cc-e27b-47b8-a4fe-edcc7ed9b29a.png?v=1666502785\", \n \"width\": 48,\n \"height\": 48\n},\n \"foundingDate\": \"2019-01-30\",\n \"sameAs\": [\n \"https:\/\/www.instagram.com\/illuminatelabs\",\n \"https:\/\/twitter.com\/illuminatelabs\",\n \"https:\/\/www.linkedin.com\/company\/illuminate-labs-supplements\",\n \"https:\/\/www.youtube.com\/channel\/UCpgSJAsIPb-fZ25djtTxBEA\"\n ]\n }\n}\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003cdiv style=\"text-align: left;\" data-mce-style=\"text-align: left;\"\u003e\u003cimg style=\"float: none;\" alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Zepbound_Review_Article_Header_Image_Optimized_4da1f9f1-7701-4fd5-900d-f8634b508269.png?v=1711826222\" data-mce-style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003ci\u003e\u003cspan\u003eDisclaimer: None of the information in this article constitutes medical advice. All statements are merely the opinion of the writer(s). We recommend that patients follow their doctor’s guidance in regard to pharmaceutical medication.\u003c\/span\u003e\u003c\/i\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"dc\"\u003eZ\u003c\/span\u003eepbound is an injectable medication that's FDA-approved for weight loss. The manufacturer's official website suggests that Zepbound helps users \"Lose Weight And Keep It Off.\"\u003c\/p\u003e\n\u003cp\u003eThe generic form of Zepbound is called tirzepatide, and we'll use these terms interchangably throughout this article, because they refer to the same active drug ingredient.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBut is Zepbound proven in clinical studies to cause weight loss? And if so, how much weight loss is possible? Does the drug cause side effects? And how do real patients rate and describe its effects?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIn this article we'll answer all of these questions and more, as we analyze clinical studies on Zepbound to determine whether or not the drug is effective for weight loss.\u003c\/p\u003e\n\u003cp\u003eWe'll compare the drug's efficacy to other popular weight loss medications like Wegovy and Mounjaro, and feature unsponsored patient reviews.\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\" data-mce-style=\"text-align: center;\"\u003e\u003cstrong\u003eDoes Zepbound Cause Weight Loss?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eZepbound has been studied in many clinical trials for its effects on weight.\u003c\/p\u003e\n\u003cp\u003eA 2022 \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35658024\/\"\u003eclinical trial\u003c\/a\u003e found that after 72 weeks of use, \u003cstrong\u003eZepbound caused an average body weight loss of 15%.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis equates to 45 pounds of weight loss for an individual with a baseline weight of 300 pounds.\u003c\/p\u003e\n\u003cp\u003eZepbound is also effective in individuals who have already lost weight through lifestyle changes.\u003c\/p\u003e\n\u003cp\u003eA \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37840095\/\"\u003eclinical trial\u003c\/a\u003e published in the \u003cem\u003eNature Portfolio\u003c\/em\u003e journal concluded that \u003cstrong\u003eZepbound \"\u003cmeta charset=\"utf-8\"\u003eprovided substantial additional reduction in body weight in participants who had achieved ≥5.0% weight reduction with intensive lifestyle intervention.\"\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBased on the available research, we consider Zepbound likely to cause weight loss in overweight and obese individuals, which is unsurprising given that the drug is FDA-approved for those indications.\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cstrong\u003eZepbound vs. the Competition\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eWegovy and Mounjaro are two of the most commonly-prescribed injectable weight loss drugs.\u003c\/p\u003e\n\u003cp\u003eA \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37344384\/\"\u003ecomparative study\u003c\/a\u003e published in the \u003cem\u003eDiabetes, Obesity and Metabolism\u003c\/em\u003e journal reported that \u003cstrong\u003eZepbound was more effective than Wegovy for weight loss.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAs we documented in our \u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/mounjaro-weight-loss\"\u003edoes Mounjaro cause weight loss\u003c\/a\u003e article, \u003cstrong\u003eMounjaro contains the same active drug ingredient, at the same doses, as Zepbound.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eTherefore, we consider Mounjaro and Zepbound equally likely to be effective.\u003c\/p\u003e\n\u003cp\u003eBased on the available research we could locate, we would recommend that patients interested in pharmaceutical weight loss treatments speak with their doctor about Zepbound or Mounjaro rather than Wegovy.\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cstrong\u003eReal People Try Zepbound\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eA TikTok creator named Elissa Lorenn shared her experience after one week on Zepbound:\u003c\/p\u003e\n\u003cblockquote class=\"tiktok-embed\" cite=\"https:\/\/www.tiktok.com\/@elissalorenn\/video\/7325242219445718303\" data-video-id=\"7325242219445718303\" style=\"max-width: 325px; min-width: 325px;\"\u003e\n\u003csection\u003e\u003ca title=\"@elissalorenn\" href=\"https:\/\/www.tiktok.com\/@elissalorenn?refer=embed\" target=\"_blank\"\u003e@elissalorenn\u003c\/a\u003e heres what ive noticed week 2 on tirzepatide ✨ \u003ca title=\"tirzepatide\" href=\"https:\/\/www.tiktok.com\/tag\/tirzepatide?refer=embed\" target=\"_blank\"\u003e#tirzepatide\u003c\/a\u003e \u003ca title=\"tirzepatideweightloss\" href=\"https:\/\/www.tiktok.com\/tag\/tirzepatideweightloss?refer=embed\" target=\"_blank\"\u003e#tirzepatideweightloss\u003c\/a\u003e \u003ca title=\"zepbound\" href=\"https:\/\/www.tiktok.com\/tag\/zepbound?refer=embed\" target=\"_blank\"\u003e#zepbound\u003c\/a\u003e \u003ca title=\"mounjaro\" href=\"https:\/\/www.tiktok.com\/tag\/mounjaro?refer=embed\" target=\"_blank\"\u003e#mounjaro\u003c\/a\u003e \u003ca title=\"mounjarojourney\" href=\"https:\/\/www.tiktok.com\/tag\/mounjarojourney?refer=embed\" target=\"_blank\"\u003e#mounjarojourney\u003c\/a\u003e \u003ca title=\"mounjaroweightloss\" href=\"https:\/\/www.tiktok.com\/tag\/mounjaroweightloss?refer=embed\" target=\"_blank\"\u003e#mounjaroweightloss\u003c\/a\u003e \u003ca title=\"weightloss\" href=\"https:\/\/www.tiktok.com\/tag\/weightloss?refer=embed\" target=\"_blank\"\u003e#weightloss\u003c\/a\u003e \u003ca title=\"♬ original sound - Elissa Lorenn\" href=\"https:\/\/www.tiktok.com\/music\/original-sound-7325242383556823839?refer=embed\" target=\"_blank\"\u003e♬ original sound - Elissa Lorenn\u003c\/a\u003e\u003c\/section\u003e\n\u003c\/blockquote\u003e\n\u003cscript src=\"https:\/\/www.tiktok.com\/embed.js\" async=\"\"\u003e\u003c\/script\u003e\n\u003cp\u003eA TikTok creator named \"veryvarine\" claims to have lost over 30 pounds using Zepbound:\u003c\/p\u003e\n\u003cblockquote style=\"max-width: 325px; min-width: 325px;\" data-video-id=\"7345073537322962218\" cite=\"https:\/\/www.tiktok.com\/@veryvarine\/video\/7345073537322962218\" class=\"tiktok-embed\"\u003e\n\u003csection\u003e\u003ca href=\"https:\/\/www.tiktok.com\/@veryvarine?refer=embed\" title=\"@veryvarine\" target=\"_blank\"\u003e@veryvarine\u003c\/a\u003e Hungover, sunburnt \u0026amp; exhausted injection this morning from the beach 🫣 still down 2 pounds this week though even though im on vacation! \u003ca href=\"https:\/\/www.tiktok.com\/tag\/fyp?refer=embed\" title=\"fyp\" target=\"_blank\"\u003e#fyp\u003c\/a\u003e \u003ca href=\"https:\/\/www.tiktok.com\/tag\/glp1?refer=embed\" title=\"glp1\" target=\"_blank\"\u003e#glp1\u003c\/a\u003e \u003ca href=\"https:\/\/www.tiktok.com\/tag\/weightloss?refer=embed\" title=\"weightloss\" target=\"_blank\"\u003e#weightloss\u003c\/a\u003e \u003ca href=\"https:\/\/www.tiktok.com\/tag\/zepbound?refer=embed\" title=\"zepbound\" target=\"_blank\"\u003e#zepbound\u003c\/a\u003e \u003ca href=\"https:\/\/www.tiktok.com\/tag\/fyp%E3%82%B7?refer=embed\" title=\"fypシ\" target=\"_blank\"\u003e#fypシ\u003c\/a\u003e \u003ca href=\"https:\/\/www.tiktok.com\/tag\/tirzepatide?refer=embed\" title=\"tirzepatide\" target=\"_blank\"\u003e#tirzepatide\u003c\/a\u003e \u003ca href=\"https:\/\/www.tiktok.com\/tag\/tirzepatideweightloss?refer=embed\" title=\"tirzepatideweightloss\" target=\"_blank\"\u003e#tirzepatideweightloss\u003c\/a\u003e \u003ca href=\"https:\/\/www.tiktok.com\/tag\/onederland?refer=embed\" title=\"onederland\" target=\"_blank\"\u003e#onederland\u003c\/a\u003e \u003ca href=\"https:\/\/www.tiktok.com\/music\/drowning-edit-7244550744096311298?refer=embed\" title=\"♬ drowning (edit) - Antent \u0026amp; vowl.\" target=\"_blank\"\u003e♬ drowning (edit) - Antent \u0026amp; vowl.\u003c\/a\u003e\u003c\/section\u003e\n\u003c\/blockquote\u003e\n\u003cscript async=\"\" src=\"https:\/\/www.tiktok.com\/embed.js\"\u003e\u003c\/script\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cstrong\u003eDoes Zepbound Cause Side Effects?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eZepbound has the potential to cause side effects.\u003c\/p\u003e\n\u003cp\u003eThe drug's \u003ca href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2023\/217806s000lbl.pdf\"\u003eFDA label\u003c\/a\u003e contains a \"black box\" warning indicating that the medication causes thyroid tumors in rats, and it's unknown whether or not the same effect may occur in humans.\u003c\/p\u003e\n\u003cp\u003eA 2023 \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/pmid\/36789109\/\"\u003emedical review\u003c\/a\u003e documented that higher doses of Zepbound were associated with greater risk of side effects.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMild side effects such as nausea and vomiting were common, although the drug also caused death in rare (\u0026lt;1%) cases, for reasons such as severe hypoglycemia and pancreatitis.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eOur Clean Weight Loss Picks\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Weight_Loss_Supplements_Image_Optimized.png?v=1686024026\" alt=\"\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThere are food-based nutrients which have been shown in medical studies to be effective for weight loss.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eD\u003c\/span\u003e\u003c\/strong\u003e\u003cb\u003eietary fiber\u003c\/b\u003e was shown in a\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6768815\/\"\u003emedical review\u003c\/a\u003e\u003cspan\u003e \u003c\/span\u003epublished in\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eThe Journal of Nutrition\u003c\/em\u003e to cause\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003e16 pounds of weight loss in 6 months\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ewhen combined with moderate caloric restriction (750 calories per day below baseline).\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003e\u003ca href=\"https:\/\/activation.healthline.com\/api\/member-offers\/8571\/redirect?lp=328\u0026amp;tc=120226\u0026amp;subid=rvosubaff_illuminatelabs\" rel=\"sponsored\"\u003eMBG Organic Fiber Potency+\u003c\/a\u003e\u003c\/strong\u003e is our top fiber pick because it's certified organic, provides 7 g of fiber per serving and costs \u003cstrong\u003eunder $1.85 per serving\u003c\/strong\u003e at the time of updating this article.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eMCT oil\u003c\/b\u003e\u003cspan\u003e was shown in a \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25636220\/\"\u003e\u003cspan\u003emeta-study\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e to cause more than one pound of weight loss over 10 weeks. \u003cstrong\u003eThis equates to potential annualized weight loss of 6 pounds per year with less than one tablespoon's worth of MCT oil per day.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003ca rel=\"sponsored\" href=\"https:\/\/bulletproof.fdf2.net\/4eNQ4M\"\u003eBulletproof MCT Oil\u003c\/a\u003e\u003c\/strong\u003e\u003cspan\u003e is our top MCT oil product, because the only ingredient is MCT oil derived from coconuts. and\u003c\/span\u003e it currently costs\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eonly\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003e$15.50 for over a month's worth of product.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eGinger\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eintake\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003e\"significantly decreased body weight\"\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eaccording to a 2019\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29393665\/\"\u003emeta-study\u003c\/a\u003e\u003cspan\u003e \u003c\/span\u003eon ginger and weight loss that analyzed data from 14 clinical trials.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003ca rel=\"sponsored\" href=\"https:\/\/piquelife.sjv.io\/QyWado\"\u003ePique La Ginger\u003c\/a\u003e\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eis our top ginger product, because it's an organic tea in convenient crystallized form, and all that's needed is to pour the powder into a glass and add hot water.\u003c\/p\u003e\n\u003cp\u003eAll three of the products mentioned in this section are entirely free of additive ingredients that we consider to be unhealthy or unsafe.\u003c\/p\u003e\n\u003cp\u003eWe are not suggesting that any of the products referenced in this section are as effective as Zepbound, or any other FDA-approved medication. Rather, we're sharing options that patients with an aversion to pharmaceutical medication may wish to speak to their doctor about. \u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cstrong\u003ePatients Rate Zepbound\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eDrugs.com is a website that allows prescription medication patients to rate and review the drugs they're taking.\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eWe cannot verify the accuracy or authenticity of any reviews on this site.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eZepbound has been reviewed over 30 times \u003ca href=\"https:\/\/www.drugs.com\/comments\/tirzepatide\/zepbound.html\"\u003eon Drugs.com\u003c\/a\u003e at the time of publishing this article, with an average review rating of 9.2 out of 10.\u003c\/p\u003e\n\u003cp\u003eA top positive review comes from a user named \"Lori\" who gave the medication a 10\/10 rating, and claims to have lost a significant amount of weight while using it:\u003c\/p\u003e\n\u003cp\u003e\"Thank you Zepbound for showing me what being full was. It's a whole new feeling. \u003cstrong\u003eI have more pep in my step. Four weeks in, over 20 pounds lost.\u003c\/strong\u003e Bring on the 2024 weight loss journey!! (2.5 dose, going up next shot)\"\u003c\/p\u003e\n\u003cp\u003eA top negative review is written by a user named \"sherri\" who gave the medication a 4\/10 rating, and seems unhappy with the weight loss:\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\"\u003cmeta charset=\"utf-8\"\u003e\u003c\/strong\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cstrong\u003eI have been on Zepbound for two months and have lost only 9 pounds\u003c\/strong\u003e...I have no side effects from the drug or overeating.\"\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003eNine pounds of weight loss in two months equates to an annualized pace of 54 pounds of weight loss, which is significant in our opinion.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cstrong\u003eWill You Regain Weight After Quitting?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003eA YouTube creator named Dr. Dan has a video on potential weight regain after use of Zepbound is discontinued:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003ciframe width=\"560\" height=\"315\" src=\"https:\/\/www.youtube.com\/embed\/L7hQHWkYcdc?si=cFQose7qZszW9511\" title=\"YouTube video player\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen=\"\"\u003e\u003c\/iframe\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cstrong\u003eWhat Does Zepbound Cost?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003eWe typically recommend that patients speak with their doctor about the generic version of drugs, because as we discussed in our \u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/orlistat-review\"\u003eorlistat reviews\u003c\/a\u003e article, clinical research has shown generics to be equally effective to brand-name drugs.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003eHowever, at the time of publishing this article, \u003cstrong\u003ethere doesn't appear to be a generic version of Zepbound available in the US\u003c\/strong\u003e because of how recently the drug was approved by the FDA.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cstrong\u003eThe retail price of Zepbound is currently around $1,050\u003c\/strong\u003e \u003ca href=\"https:\/\/www.goodrx.com\/zepbound\"\u003eaccording to\u003c\/a\u003e GoodRx.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003eThe drug manufacturer's website has a \u003ca href=\"https:\/\/zepbound.lilly.com\/coverage-savings\"\u003eSavings Page\u003c\/a\u003e that claims to help patients spend as little as $25 if they qualify.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cstrong\u003eConclusion\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003eZepbound is highly effective for weight loss in overweight and obese individuals.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003eThis drug was recently approved by the FDA, and appears to be more effective than older-generation injectable weight loss drugs.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003eZepbound has the potential to cause severe side effects, including death, so we strongly encourage patients to speak with their doctor about the risks before using this medication.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003eSome patients may regain weight when discontinuing Zepbound.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\"\u003eAt the time of publishing this article, Zepbound has one of the highest average patient ratings on Drugs.com that we've ever noted in an Illuminate Health review.\u003c\/span\u003e\u003c\/p\u003e","blog_id":49281925193,"author":"Calloway Cook","user_id":26601750601,"published_at":"2024-03-30T23:32:38-04:00","updated_at":"2024-03-30T23:32:38-04:00","summary_html":"We analyze clinical studies on Zepbound to give our take on whether or not it's likely to cause weight loss, and if so, how much. We compare Zepbound to other injectable weight loss drugs like Wegovy, and feature unsponsored patient reviews.","template_suffix":"","handle":"zepbound-review","tags":"_related:weight-loss"}

Zepbound Review: The New & Improved Ozempic?

Zepbound Review: The New & Improved Ozempic?


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Disclaimer: None of the information in this article constitutes medical advice. All statements are merely the opinion of the writer(s). We recommend that patients follow their doctor’s guidance in regard to pharmaceutical medication.

Zepbound is an injectable medication that's FDA-approved for weight loss. The manufacturer's official website suggests that Zepbound helps users "Lose Weight And Keep It Off."

The generic form of Zepbound is called tirzepatide, and we'll use these terms interchangably throughout this article, because they refer to the same active drug ingredient.

But is Zepbound proven in clinical studies to cause weight loss? And if so, how much weight loss is possible? Does the drug cause side effects? And how do real patients rate and describe its effects?

In this article we'll answer all of these questions and more, as we analyze clinical studies on Zepbound to determine whether or not the drug is effective for weight loss.

We'll compare the drug's efficacy to other popular weight loss medications like Wegovy and Mounjaro, and feature unsponsored patient reviews.

Does Zepbound Cause Weight Loss?

Zepbound has been studied in many clinical trials for its effects on weight.

A 2022 clinical trial found that after 72 weeks of use, Zepbound caused an average body weight loss of 15%.

This equates to 45 pounds of weight loss for an individual with a baseline weight of 300 pounds.

Zepbound is also effective in individuals who have already lost weight through lifestyle changes.

A clinical trial published in the Nature Portfolio journal concluded that Zepbound "provided substantial additional reduction in body weight in participants who had achieved ≥5.0% weight reduction with intensive lifestyle intervention."

Based on the available research, we consider Zepbound likely to cause weight loss in overweight and obese individuals, which is unsurprising given that the drug is FDA-approved for those indications.

Zepbound vs. the Competition

Wegovy and Mounjaro are two of the most commonly-prescribed injectable weight loss drugs.

A comparative study published in the Diabetes, Obesity and Metabolism journal reported that Zepbound was more effective than Wegovy for weight loss.

As we documented in our does Mounjaro cause weight loss article, Mounjaro contains the same active drug ingredient, at the same doses, as Zepbound.

Therefore, we consider Mounjaro and Zepbound equally likely to be effective.

Based on the available research we could locate, we would recommend that patients interested in pharmaceutical weight loss treatments speak with their doctor about Zepbound or Mounjaro rather than Wegovy.

Real People Try Zepbound

A TikTok creator named Elissa Lorenn shared her experience after one week on Zepbound:

@elissalorenn heres what ive noticed week 2 on tirzepatide ✨ #tirzepatide #tirzepatideweightloss #zepbound #mounjaro #mounjarojourney #mounjaroweightloss #weightloss ♬ original sound - Elissa Lorenn

A TikTok creator named "veryvarine" claims to have lost over 30 pounds using Zepbound:

@veryvarine Hungover, sunburnt & exhausted injection this morning from the beach 🫣 still down 2 pounds this week though even though im on vacation! #fyp #glp1 #weightloss #zepbound #fypシ #tirzepatide #tirzepatideweightloss #onederland ♬ drowning (edit) - Antent & vowl.

Does Zepbound Cause Side Effects?

Zepbound has the potential to cause side effects.

The drug's FDA label contains a "black box" warning indicating that the medication causes thyroid tumors in rats, and it's unknown whether or not the same effect may occur in humans.

A 2023 medical review documented that higher doses of Zepbound were associated with greater risk of side effects.

Mild side effects such as nausea and vomiting were common, although the drug also caused death in rare (<1%) cases, for reasons such as severe hypoglycemia and pancreatitis.

Our Clean Weight Loss Picks

There are food-based nutrients which have been shown in medical studies to be effective for weight loss.

Dietary fiber was shown in a medical review published in The Journal of Nutrition to cause 16 pounds of weight loss in 6 months when combined with moderate caloric restriction (750 calories per day below baseline).

MBG Organic Fiber Potency+ is our top fiber pick because it's certified organic, provides 7 g of fiber per serving and costs under $1.85 per serving at the time of updating this article.

MCT oil was shown in a meta-study to cause more than one pound of weight loss over 10 weeks. This equates to potential annualized weight loss of 6 pounds per year with less than one tablespoon's worth of MCT oil per day.

Bulletproof MCT Oil is our top MCT oil product, because the only ingredient is MCT oil derived from coconuts. and it currently costs only $15.50 for over a month's worth of product.

Ginger intake "significantly decreased body weight" according to a 2019 meta-study on ginger and weight loss that analyzed data from 14 clinical trials.

Pique La Ginger is our top ginger product, because it's an organic tea in convenient crystallized form, and all that's needed is to pour the powder into a glass and add hot water.

All three of the products mentioned in this section are entirely free of additive ingredients that we consider to be unhealthy or unsafe.

We are not suggesting that any of the products referenced in this section are as effective as Zepbound, or any other FDA-approved medication. Rather, we're sharing options that patients with an aversion to pharmaceutical medication may wish to speak to their doctor about. 

Patients Rate Zepbound

Drugs.com is a website that allows prescription medication patients to rate and review the drugs they're taking.

We cannot verify the accuracy or authenticity of any reviews on this site.

Zepbound has been reviewed over 30 times on Drugs.com at the time of publishing this article, with an average review rating of 9.2 out of 10.

A top positive review comes from a user named "Lori" who gave the medication a 10/10 rating, and claims to have lost a significant amount of weight while using it:

"Thank you Zepbound for showing me what being full was. It's a whole new feeling. I have more pep in my step. Four weeks in, over 20 pounds lost. Bring on the 2024 weight loss journey!! (2.5 dose, going up next shot)"

A top negative review is written by a user named "sherri" who gave the medication a 4/10 rating, and seems unhappy with the weight loss:

"I have been on Zepbound for two months and have lost only 9 pounds...I have no side effects from the drug or overeating."

Nine pounds of weight loss in two months equates to an annualized pace of 54 pounds of weight loss, which is significant in our opinion.

Will You Regain Weight After Quitting?

A YouTube creator named Dr. Dan has a video on potential weight regain after use of Zepbound is discontinued:

What Does Zepbound Cost?

We typically recommend that patients speak with their doctor about the generic version of drugs, because as we discussed in our orlistat reviews article, clinical research has shown generics to be equally effective to brand-name drugs.

However, at the time of publishing this article, there doesn't appear to be a generic version of Zepbound available in the US because of how recently the drug was approved by the FDA.

The retail price of Zepbound is currently around $1,050 according to GoodRx.

The drug manufacturer's website has a Savings Page that claims to help patients spend as little as $25 if they qualify.

Stay up-to-date on our research reviews

Conclusion

Zepbound is highly effective for weight loss in overweight and obese individuals.

This drug was recently approved by the FDA, and appears to be more effective than older-generation injectable weight loss drugs.

Zepbound has the potential to cause severe side effects, including death, so we strongly encourage patients to speak with their doctor about the risks before using this medication.

Some patients may regain weight when discontinuing Zepbound.

At the time of publishing this article, Zepbound has one of the highest average patient ratings on Drugs.com that we've ever noted in an Illuminate Health review.