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{"id":555890114633,"title":"ZuPOO Review: Why \"Colon Cleansing\" Doesn't Work","created_at":"2021-10-07T11:14:55-04:00","body_html":"\u003cscript type=\"application\/ld+json\"\u003e\/\/ \u003c![CDATA[\n{\n \"@context\": \"https:\/\/schema.org\",\n \"@type\": \"Article\",\n \"headline\": \"ZuPOO Review: Why 'Colon Cleansing' Doesn't Work\",\n \"keywords\": \"zupoo, zupoo review, zupoo reviews, umzu zupoo, zupoo colon cleanse, umzu zupoo reviews, zupoo cleanse, zupoo ingredients\",\n \"description\": \"Our MD breaks down the formulation of ZuPOO and explains why we don't believe the supplement benefits health in any way. We also review some health claims made by Umzu which are unsafe and deceptive.\",\n \"url\": \"https:\/\/illuminatelabs.org\/blogs\/health\/zupoo-review\",\n\"author\": {\n \"@type\": \"Person\",\n \"name\": \"Taylor Graber MD\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/taylor-graber\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/taylor-j-graber-md-81351642\/\",\n \"jobTitle\": \"Content Partner\",\n \"knowsAbout\": \"medicine, health, anesthesiology, iv therapy, science, drugs, pharmaceutical, medical research, scientific research, medical journals, entrepreneurship, healthcare, orthopedic surgery, biomedical engineering\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"University of California San Diego\",\n \"Arizona University\",\n \"University of Arizona College of Medicine\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"contributor\": {\n \"@type\": \"Person\",\n \"name\": \"Calloway Cook\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/calloway-cook\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/calloway-cook\/\",\n \"jobTitle\": \"President\",\n \"knowsAbout\": \"entrepreneurship, dietary supplements, herbal supplements, eCommerce, medical research\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": \"S.I. Newhouse School of Public Communications at Syracuse University\"\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"editor\": {\n \"@type\": \"Person\",\n \"name\": \"DJ Mazzoni\",\n \"honorificSuffix\": [\n \"M.S.\",\n \"R.D.\",\n \"C.D.N.\",\n \"C.S.C.S.\"\n ],\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/dj-mazzoni\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/dj-mazzoni-rd-cdn-cscs-00a33038\/\",\n \"jobTitle\": \"Medical Reviewer\",\n \"knowsAbout\": \"exercise, drugs, pharmaceutical, health, workout, strength and conditioning, nutrition, dietetics, medicine, medical research, scientific research, scientific method, healthcare, patient care, wellness\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"State University of New York College Oswego\",\n \"D’Youville College\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"image\": {\n\"@type\": \"ImageObject\",\n\"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/ZuPoo_Thumbnail.jpg?v=1642440572\",\n\"width\": \"1472\",\n\"height\": \"1472\"\n},\n\"citation\": [\n\"https:\/\/illuminatelabs.org\/blogs\/health\/umzu-review\", \n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19724266\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25527456\/\",\n\"https:\/\/chriswalker.io\/about-christopher-walker\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20205503\/\",\n\"https:\/\/www.hopkinsmedicine.org\/health\/conditions-and-diseases\/toxic-megacolon\",\n\"https:\/\/illuminatelabs.org\/blogs\/health\/balance-of-nature-review\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK548113\/\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK541075\/\"\n],\n\"datePublished\": \"2021-12-21\",\n\"copyrightHolder\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n},\n\"publisher\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\",\n \"url\": \"https:\/\/illuminatelabs.org\/\",\n \"description\": \"Illuminate Labs is the most transparent supplement company in the U.S., and is a leading publisher of research-based health information.\",\n \"knowsAbout\": \"supplements, science, nutrition, exercise, health, medication, pharmaceutical, wellness, diet, weight loss, medical research\",\n \"publishingPrinciples\": \"https:\/\/illuminatelabs.org\/pages\/editorial-guidelines\",\n \"logo\": {\n \"@type\": \"ImageObject\",\n \"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Illuminate_Labs_Logo.png?v=1641249064\", \n \"width\": 150,\n \"height\": 150\n},\n \"foundingDate\": \"2019-01-30\",\n \"Address\": {\n \"@type\": \"PostalAddress\",\n \"streetAddress\": \"50 Union Street, Unit 9\",\n \"addressLocality\": \"Northampton\",\n \"addressRegion\": \"Massachusetts\",\n \"postalCode\": \"01060\",\n \"addressCountry\": \"US\"\n},\n \"sameAs\": [\n \"https:\/\/www.instagram.com\/illuminatelabs\",\n \"https:\/\/twitter.com\/illuminatelabs\",\n \"https:\/\/www.linkedin.com\/company\/illuminate-labs-supplements\",\n \"https:\/\/www.youtube.com\/channel\/UCpgSJAsIPb-fZ25djtTxBEA\"\n ]\n }\n}\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003e\u003cem\u003e\u003c\/em\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/ZuPOO_Review_Article_Header_Image_Optimized.png?v=1633620082\" alt=\"\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cspan class=\"dc\"\u003eZ\u003c\/span\u003euPOO is a supplement from Umzu that claims to function as a colon cleanse and provide gut support. We \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/umzu-review\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ealready reviewed\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e Umzu as a brand, but wanted to analyze the formulation of this product since it wasn’t in our original review and it’s gaining in popularity.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn this article we’ll review the ingredients in ZuPOO based on medical research to determine if it’s likely to be effective. We'll also review some health claims made by Umzu and explain why we find them to be misleading.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eStrange and Unscientific Health Claims\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/ZuPOO_Misleading_Health_Claims.png?v=1633620226\" alt=\"ZuPOO misleading health claims\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe entire premise behind this product is strange. There isn’t much of any medical research suggesting that the colon needs to be “cleansed” of “waste”. That’s taken care of by our digestive system and by defecating.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19724266\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in the American Journal of Gastroenterology concluded that there was no proof that colon cleansing had any medical benefit, and that it carried risks of harm.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25527456\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emore recent clinical study\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e found that colon cleansing (which was recommended prior to a colonoscopy) had negative effects on microbiota: it significantly reduced the levels of healthy bacteria in the short-term.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eUmzu wrote an absolutely absurd and dangerous blog post pushing this product, titled “Scientists Confirm: The Average Person is Carrying Around 5-20 Pounds of Poop in Their Body At Any Time”.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThis article makes several explicitly false claims. One claim is that “if you are not producing well-formed stools after each meal, then you are most likely suffering from a toxic buildup inside your digestive system.”\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThis is false, not cited, and dangerous medical advice. It’s written by Umzu’s co-founder Christopher Walker who has no medical credentials, and claims \u003c\/span\u003e\u003ca href=\"https:\/\/chriswalker.io\/about-christopher-walker\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ein a blog post\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e on his personal website to be “disgusted by the medical system.”\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20205503\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ethorough medical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e proved that normal bowel frequency is between three times weekly and three times daily. That’s a wide range, and much different from the unsourced claim in Umzu’s blog post.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe article also claims that “all that poop, just sitting there, rotting away inside their intestines and colon” which is another misleading claim that shows a lack of basic understanding of human biology. Stool doesn’t “just sit” in the intestines and it certainly doesn’t “rot” -- it passes through the digestive tract before being expelled.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eUmzu claims that “As this toxic waste builds up, your body becomes a walking vessel of fecal toxicity”. They seem to be claiming that regular bowel function poses a life-threatening risk. That is false and makes no sense. Fecal toxicity is an \u003c\/span\u003e\u003ca href=\"https:\/\/www.hopkinsmedicine.org\/health\/conditions-and-diseases\/toxic-megacolon\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eincredibly rare complication\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e of severe colon disease or infection. It’s not something you just get because you weren’t taking supplements sold by a heretic online who has no understanding of basic human anatomy.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThese uncited health claims made by Umzu should be enough of a red flag to avoid the company entirely, but we’ll proceed to the ingredient review for those curious.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eIngredient Review\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/ZuPOO_Ingredients.png?v=1633620142\" alt=\"ZuPOO ingredients list\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eZuPOO is formulated with a proprietary (prop) blend totalling 1,270 milligrams (mg).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIf you’ve read our previous reviews like the \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/balance-of-nature-review\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eBalance of Nature\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e one, you’ll know that we find prop blends to be deceptive because they only list the dosage of the total blend instead of each ingredient. This allows manufacturers to evade analysis of whether each ingredient is effectively dosed, and to include tiny amounts of exotic ingredients at the bottom of the blend to make it look more impressive.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe highest-dose ingredient in ZuPOO is Cascara Sagrada Bark Extract, which is a laxative. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK548113\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eMedical research shows\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e that cascara is likely safe short-term, but has been associated with several case reports of acute liver injury when taken long-term. We do not believe the risk is worth it in this case, because there is no medical benefit for healthy people to take laxatives regularly.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eZuPOO’s Supplement Facts label indicates that cascara supports “healthy bowel movements”, which is misleading. Regular, healthy people do not attain any additional benefit from taking laxatives. These compounds simply make you defecate faster, not “healthier”.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe second ingredient, senna leaf powder, is also laxative in nature. Consumers likely are misled into believing their digestive system is being “cleansed” when they feel the effects of these two powerful laxatives at once.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe can’t find any medical research for any of the included ingredients supporting Umzu’s claim of “Gut Support” for this product.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn fact, one of the ingredients actually has side effects of gut distress. Milk thistle, which is typically used for liver protection, has \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK541075\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003epublished side effects\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e of gut dysfunction. These side effects are rare, but it just goes to show how poorly formulated a product is when an ingredient is included with no apparent benefit for the stated health claim, and has a side effect profile that’s directly in opposition to the stated health claim.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eUmzu cites zero of their health claims on ZuPOO’s product page, so we have no reason to believe any of them are accurate.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThis is one of the worst-formulated products we’ve ever reviewed, and we can’t recommend avoiding this brand enough.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eConclusion\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe have no reason to believe that ZuPOO is effective for improving health in any way, and we believe the product may be dangerous if used long-term due to its active ingredient of Cascara Sagrada bark extract.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eUmzu does not provide a single medical source on their ZuPOO product page for any of the claims they make, and they published a blog post to market the product which was rife with medical inaccuracies and was boldly deceptive.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe recommend you avoid this brand and product entirely. There is no medical evidence supporting the concept of “colon cleanses” for general health maintenance. Your body takes care of that just fine.\u003c\/span\u003e\u003c\/p\u003e","blog_id":49281925193,"author":"Calloway Cook","user_id":26601750601,"published_at":"2021-11-21T00:30:00-05:00","updated_at":"2022-08-18T20:20:03-04:00","summary_html":"We review the formulation of ZuPOO and explain why we don't believe the supplement benefits health in any way. We also review some health claims made by Umzu which are unsafe and deceptive.","template_suffix":"","handle":"zupoo-review","tags":"_related:gut-health"}

ZuPOO Review: Why "Colon Cleansing" Doesn't Work

ZuPOO Review: Why "Colon Cleansing" Doesn't Work


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Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.


Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.

ZuPOO is a supplement from Umzu that claims to function as a colon cleanse and provide gut support. We already reviewed Umzu as a brand, but wanted to analyze the formulation of this product since it wasn’t in our original review and it’s gaining in popularity.

In this article we’ll review the ingredients in ZuPOO based on medical research to determine if it’s likely to be effective. We'll also review some health claims made by Umzu and explain why we find them to be misleading.

Strange and Unscientific Health Claims

ZuPOO misleading health claims

The entire premise behind this product is strange. There isn’t much of any medical research suggesting that the colon needs to be “cleansed” of “waste”. That’s taken care of by our digestive system and by defecating.

A medical review published in the American Journal of Gastroenterology concluded that there was no proof that colon cleansing had any medical benefit, and that it carried risks of harm.

A more recent clinical study found that colon cleansing (which was recommended prior to a colonoscopy) had negative effects on microbiota: it significantly reduced the levels of healthy bacteria in the short-term.

Umzu wrote an absolutely absurd and dangerous blog post pushing this product, titled “Scientists Confirm: The Average Person is Carrying Around 5-20 Pounds of Poop in Their Body At Any Time”.

This article makes several explicitly false claims. One claim is that “if you are not producing well-formed stools after each meal, then you are most likely suffering from a toxic buildup inside your digestive system.”

This is false, not cited, and dangerous medical advice. It’s written by Umzu’s co-founder Christopher Walker who has no medical credentials, and claims in a blog post on his personal website to be “disgusted by the medical system.”

A thorough medical review proved that normal bowel frequency is between three times weekly and three times daily. That’s a wide range, and much different from the unsourced claim in Umzu’s blog post.

The article also claims that “all that poop, just sitting there, rotting away inside their intestines and colon” which is another misleading claim that shows a lack of basic understanding of human biology. Stool doesn’t “just sit” in the intestines and it certainly doesn’t “rot” -- it passes through the digestive tract before being expelled.

Umzu claims that “As this toxic waste builds up, your body becomes a walking vessel of fecal toxicity”. They seem to be claiming that regular bowel function poses a life-threatening risk. That is false and makes no sense. Fecal toxicity is an incredibly rare complication of severe colon disease or infection. It’s not something you just get because you weren’t taking supplements sold by a heretic online who has no understanding of basic human anatomy.

These uncited health claims made by Umzu should be enough of a red flag to avoid the company entirely, but we’ll proceed to the ingredient review for those curious.

Ingredient Review

ZuPOO ingredients list

ZuPOO is formulated with a proprietary (prop) blend totalling 1,270 milligrams (mg).

If you’ve read our previous reviews like the Balance of Nature one, you’ll know that we find prop blends to be deceptive because they only list the dosage of the total blend instead of each ingredient. This allows manufacturers to evade analysis of whether each ingredient is effectively dosed, and to include tiny amounts of exotic ingredients at the bottom of the blend to make it look more impressive.

The highest-dose ingredient in ZuPOO is Cascara Sagrada Bark Extract, which is a laxative. 

Medical research shows that cascara is likely safe short-term, but has been associated with several case reports of acute liver injury when taken long-term. We do not believe the risk is worth it in this case, because there is no medical benefit for healthy people to take laxatives regularly.

ZuPOO’s Supplement Facts label indicates that cascara supports “healthy bowel movements”, which is misleading. Regular, healthy people do not attain any additional benefit from taking laxatives. These compounds simply make you defecate faster, not “healthier”.

The second ingredient, senna leaf powder, is also laxative in nature. Consumers likely are misled into believing their digestive system is being “cleansed” when they feel the effects of these two powerful laxatives at once.

We can’t find any medical research for any of the included ingredients supporting Umzu’s claim of “Gut Support” for this product.

In fact, one of the ingredients actually has side effects of gut distress. Milk thistle, which is typically used for liver protection, has published side effects of gut dysfunction. These side effects are rare, but it just goes to show how poorly formulated a product is when an ingredient is included with no apparent benefit for the stated health claim, and has a side effect profile that’s directly in opposition to the stated health claim.

Umzu cites zero of their health claims on ZuPOO’s product page, so we have no reason to believe any of them are accurate.

This is one of the worst-formulated products we’ve ever reviewed, and we can’t recommend avoiding this brand enough.

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Conclusion

We have no reason to believe that ZuPOO is effective for improving health in any way, and we believe the product may be dangerous if used long-term due to its active ingredient of Cascara Sagrada bark extract.

Umzu does not provide a single medical source on their ZuPOO product page for any of the claims they make, and they published a blog post to market the product which was rife with medical inaccuracies and was boldly deceptive.

We recommend you avoid this brand and product entirely. There is no medical evidence supporting the concept of “colon cleanses” for general health maintenance. Your body takes care of that just fine.





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