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Uqora Review: Natural Prevention of Recurrent UTI?

Uqora Review: Natural Prevention of Recurrent UTI?

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Uqora is a supplement brand that makes products for urinary tract health, and their marketing is targeted mostly to women. We haven’t come across much research on supplements for urinary tract health, so we’re curious to see how the health claims made by Uqora hold up to scientific research.

In this article we’ll review the formulation of Uqora’s supplements based on published medical studies to determine if they’re likely to improve urinary tract health or if they’re a waste of money.

Uqora Target Review

Uqora’s most popular product is a powder supplement called Target, which makes several strange health claims. The brand claims this product can “gently flush the urinary tract” and “increase urinary flow”.

We’re unclear what the company means by “flushing” the urinary tract, as standard urination does so. The company provides no research explaining these claims, and they seem unscientific to us.

The formulation of this product consists of a vitamin and mineral blend, along with 2 grams (g) of a sugar monomer called d-mannose. 

D-mannose has been shown in a medical trial to be effective for urinary tract infections (UTI) in women, at a dose similar to that in Uqora Target.

A separate medical review published in the European Urology Focus journal analyzed 6 different studies on the efficacy of d-mannose for prevention of recurrent urinary tract infections. The researchers found that mannose reduced the incidence of urinary tract infections and improved patient quality of life.

We can’t identify any research suggesting the seemingly random blend of vitamins and minerals included in this product is effective for urinary tract health, and Uqora doesn’t publish any. In fact, one medical review highlighted an increased risk of UTI with calcium supplementation. Calcium is included in Target.

Overall we find this to be a relatively poor formulation, with only one ingredient seeming to be effective for urinary tract health. We also disagree with the specific health claims made by the brand, and find it strange that they make claims in regards to urinary flow and “flushing” the urinary tract rather than potential prevention of recurrent UTI which at least has some basis in medical research.

Since d-mannose at a dose of 2 g appears to be the only effective ingredient in this formulation for urinary tract health, we recommend that consumers speak with their doctor about taking d-mannose alone. It would be cheaper than taking it in this product which contains many seemingly unnecessary alternative ingredients.

Uqora Control Review

Uqora claims that their supplement called Control “cleanses biofilm” and “strengthens the bladder wall.” We cannot find much research supporting these claims, and Uqora doesn’t publish any.

This product also contains d-mannose, but at a lower dose of 600 milligrams (mg); less than one-third of that in Target. This appears to be underdosed for improving urinary tract health based on the studies we reviewed in the previous section.

Control also contains 1,500 International Units (IU) of Vitamin D3. While Vitamin D deficiency was associated with lower urinary tract symptoms in men in a medical review, we can’t find any data suggesting its supplementation is effective for urinary health in patients who aren’t deficient.

We generally believe that taking random blends of vitamins is illogical, and that vitamin supplements should be targeted based on deficiency. For patients with normal levels of vitamins, there is no additional benefit to supplementation.

Control contains a turmeric and black pepper extract blend at respective dosages of 200 mg and 10 mg. We located one study suggesting curcumin (the active chemical compound in turmeric) may be effective for biofilm disruption, but it was an in vitro (test tube) study, rather than a study with human subjects which would be much stronger data. We don’t believe this one preliminary trial supports the health claims of Uqora.

Green tea extract is the final ingredient in Control. There is some research suggesting green tea extract may be effective for biofilm disruption, but this review looked at test tube data.

A human observational study linked increased green tea consumption to reduced incidence of UTI.

Overall we believe this is a slightly better formulation than Target, but we still wouldn’t recommend it because we find the data backing these ingredients to be far too preliminary to suggest this product is effective. It’s important to note that the ingredients in this product at the dosages included have never been proven to be effective for any urinary tract health condition.

Since increased green tea consumption has been associated with lower risk of UTI, consumers may want to consider increasing green tea intake if recurrent UTI is an issue they suffer from. Drinking green tea would be much more cost-effective than purchasing Uqora Control.

Uqora Promote Review

Uqora’s third supplement is called Promote, and contains a prebiotic and probiotic blend. One notable point is that only the probiotic species is listed, and not the strain. As we discussed in our Fungus Clear review (another supplement brand with the same issue), different strains of probiotics within the same species can have different effects. 

Our opinion is that supplements which only list the general probiotic species are doing consumers (and researchers like us) a disservice because it makes it challenging to determine whether the product is likely to be effective or not.

We can’t find any medical research suggesting the prebiotic used by Uqora (fructo-ogliosaccharides) is effective for improving urinary tract health.

A medical study on probiotics for UTIs proves our point about the importance of probiotic strains. The researchers found no statistically significant difference in the groups taking lactobacillus probiotics (one of the species in Promote) versus controls in general, but after filtering out ineffective strains they did note a difference.

Without knowing what specific lactobacillus strains are used in this product we can’t conclusively say whether it should be effective.

This product appears to be a safe formulation, and probiotics have documented health effects in general, but we don’t recommend this product because we don’t believe research backs its specific health claims.

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Uqora seems to make decently formulated products for urinary tract health, with some of the ingredients they use being effective. We don’t recommend the brand overall because we find them to use many ineffective ingredients and we disagree with many of the health claims they make.

Consumers interested in naturally improving urinary tract health may wish to speak with their doctor about d-mannose supplementation at a daily dose of 2 g, and green tea consumption, as these two interventions have been shown in research reviewed in this article to improve urinary tract health.

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