Get $25 Off On Subscription Orders!

{"id":556358467657,"title":"Tula Skincare Review: Do Probiotics Improve Skin?","created_at":"2022-04-01T00:36:56-04:00","body_html":"\u003cscript type=\"application\/ld+json\"\u003e\/\/ \u003c![CDATA[\n{\n \"@context\": \"https:\/\/schema.org\",\n \"@type\": \"Article\",\n \"headline\": \"Tula Skincare Review: Do Probiotics Improve Skin?\",\n \"keywords\": \"tula, tula skincare, tula skincare review, tula skincare reviews, tula skincare, tula sunscreen, tula eye balm\",\n \"description\": \"Our MD and research team reviews the ingredients in some of Tula’s most popular products based on published medical research to determine if they’re effective or a waste of money. We highlight some safety issues we find concerning with the brand.\",\n \"url\": \"https:\/\/illuminatelabs.org\/blogs\/health\/tula-skincare-review\",\n\"author\": {\n \"@type\": \"Person\",\n \"name\": \"Taylor Graber MD\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/taylor-graber\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/taylor-j-graber-md-81351642\/\",\n \"jobTitle\": \"Content Partner\",\n \"knowsAbout\": \"medicine, health, anesthesiology, iv therapy, science, drugs, pharmaceutical, medical research, scientific research, medical journals, entrepreneurship, healthcare, orthopedic surgery, biomedical engineering\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"University of California San Diego\",\n \"Arizona University\",\n \"University of Arizona College of Medicine\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"contributor\": {\n \"@type\": \"Person\",\n \"name\": \"Calloway Cook\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/calloway-cook\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/calloway-cook\/\",\n \"jobTitle\": \"President\",\n \"knowsAbout\": \"entrepreneurship, dietary supplements, herbal supplements, eCommerce, medical research\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": \"S.I. Newhouse School of Public Communications at Syracuse University\"\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"editor\": {\n \"@type\": \"Person\",\n \"name\": \"DJ Mazzoni\",\n \"honorificSuffix\": [\n \"M.S.\",\n \"R.D.\",\n \"C.D.N.\",\n \"C.S.C.S.\"\n ],\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/dj-mazzoni\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/dj-mazzoni-rd-cdn-cscs-00a33038\/\",\n \"jobTitle\": \"Medical Reviewer\",\n \"knowsAbout\": \"exercise, drugs, pharmaceutical, health, workout, strength and conditioning, nutrition, dietetics, medicine, medical research, scientific research, scientific method, healthcare, patient care, wellness\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"State University of New York College Oswego\",\n \"D’Youville College\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"image\": {\n\"@type\": \"ImageObject\",\n\"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Tula_Skincare_Thumbnail.jpg?v=1648788523\",\n\"width\": \"3029\",\n\"height\": \"3029\"\n},\n\"citation\": [\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8955881\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31257694\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19624730\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27161285\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27213821\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35048513\/\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6477564\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22940465\/\",\n\"https:\/\/www.jdsupra.com\/legalnews\/european-union-s-lilial-ban-puts-social-6324675\/\",\n\"https:\/\/illuminatelabs.org\/blogs\/health\/elta-md-sunscreen-review\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31016361\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31021040\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23026007\/\"\n],\n\"mentions\": [{\n \"@type\": \"Thing\",\n \"name\": \"Dr. Roshini Raj\"\n},\n{\n\"@type\": \"Thing\",\n \"name\": \"Hydrating Day \u0026 Night Cream\"\n},\n{\n\"@type\": \"Thing\",\n \"name\": \"fragrance\"\n},\n{\n\"@type\": \"Thing\",\n \"name\": \"chemical sunscreen\"\n},\n{\n\"@type\": \"Thing\",\n \"name\": \"Glow \u0026 Get It\"\n}\n],\n\"datePublished\": \"2022-04-01\",\n\"copyrightHolder\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n},\n\"publisher\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\",\n \"url\": \"https:\/\/illuminatelabs.org\/\",\n \"description\": \"Illuminate Labs is the most transparent supplement company in the U.S., and is a leading publisher of research-based health information.\",\n \"knowsAbout\": \"supplements, science, nutrition, exercise, health, medication, pharmaceutical, wellness, diet, weight loss, medical research\",\n \"publishingPrinciples\": \"https:\/\/illuminatelabs.org\/pages\/editorial-guidelines\",\n \"memberOf\": [\n {\n \"@type\": \"Organization\",\n \"name\": \"U.S. Chamber of Commerce\",\n \"url\": \"https:\/\/www.uschamber.com\/\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Certified B Corp\",\n \"url\": \"https:\/\/www.bcorporation.net\/en-us\/\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Natural Products Association\",\n \"url\": \"https:\/\/www.npanational.org\/\"\n }\n ], \n \"logo\": {\n \"@type\": \"ImageObject\",\n \"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Illuminate_Labs_Logo.png?v=1641249064\", \n \"width\": 150,\n \"height\": 150\n},\n \"foundingDate\": \"2019-01-30\",\n \"Address\": {\n \"@type\": \"PostalAddress\",\n \"streetAddress\": \"50 Union Street, Unit 9\",\n \"addressLocality\": \"Northampton\",\n \"addressRegion\": \"Massachusetts\",\n \"postalCode\": \"01060\",\n \"addressCountry\": \"US\"\n},\n \"sameAs\": [\n \"https:\/\/www.instagram.com\/illuminatelabs\",\n \"https:\/\/twitter.com\/illuminatelabs\",\n \"https:\/\/www.linkedin.com\/company\/illuminate-labs-supplements\",\n \"https:\/\/www.youtube.com\/channel\/UCpgSJAsIPb-fZ25djtTxBEA\"\n ]\n }\n}\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Tula_Skincare_Review_Article_Header_Image_Optimized.png?v=1648788260\" alt=\"\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cspan class=\"dc\"\u003eT\u003c\/span\u003eula is a cosmetics brand with an interesting premise: that topically-applied probiotics can improve skin quality. Their founder is a dermatologist named Dr. Roshini Raj, and the brand sells products for acne, anti-aging, dark spots and oily skin.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn this article we’ll review the ingredients in some of Tula’s most popular products based on published medical research to determine if they’re likely to be effective at improving skin quality. We’ll also analyze whether topically-applied probiotics have generally been found effective in medical studies.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eDo Topical Probiotics Work?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe skin naturally has a variety of up to 1,000 healthy bacteria, referred to as the skin microbiome. When we refer to the “microbiome,” we’re typically referring to the bacteria in our gut, but we coexist with beneficial bacteria in the skin too.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMedical research has found that topically-applied probiotics can have a positive effect on inflammatory skin conditions. A 2022 \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8955881\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ereview\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in the Pharmaceutics journal found that topical probiotics have demonstrated positive outcomes for a wide variety of skin conditions: acne, rosacea, psoriasis and dandruff to name a few.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThere’s also some early research that topical probiotics may be effective for anti-aging. A \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31257694\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e from 2020 found that a topical probiotic called Nitrosomonas eutropha reduced the appearance of wrinkles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMost of the research on topical probiotics is very recent. It looks promising, but we believe it’s too early to conclusively state that topical probiotics are effective. It’s definitely too early, in our opinion, to state that topical probiotics are effective for anti-aging.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe need more medical studies to determine which topical probiotic strains are effective for which skin conditions and\/or aging skin. Just because one probiotic strain is effective doesn’t mean all are, because every strain has unique effects.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eTula Moisturizing Cream Review\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Tula_Moisturizing_Cream_Ingredients_480x480.png?v=1648788354\" alt=\"Tula moisturizing cream ingredients\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eTula’s best-selling product is their moisturizing cream, called Hydrating Day \u0026amp; Night Cream. The brand claims it can provide “all day hydration” and “revive the appearance of dull and tired skin.” There’s also a claimed anti-aging effect.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThis cream has 54 individual ingredients which seems excessive for a basic moisturizing product. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe product page advertises the inclusion of peptides, but we don’t see any peptides in the full ingredients list, which is quite strange.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe product page also advertises “probiotic extracts,” but we only identify one single probiotic extract on the ingredients list: \u003c\/span\u003e\u003cb\u003eBifida Ferment Lysate\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e. We were able to locate \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19624730\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eone medical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e proving that this ingredient had a beneficial impact on reactive skin, at a concentration of 10%.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThere doesn’t appear to be any medical evidence that this probiotic is effective for skin hydration or anti-aging, and Tula doesn’t publish the concentration of this ingredient in their formulation, so we have no reason to believe it’s effective.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThere’s also the extremely confusing statement that the product “does not contain live cultures.” Probiotics, definitionally, are live cultures. So Tula is marketing this cream as a probiotic cream but also noting that there are no live probiotics in the formulation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eChicory root extract\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is another active ingredient in Tula’s moisturizer, and this does appear to be an effective ingredient. A recent \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27161285\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in the Journal of Dermatological Treatment found that this botanical compound showed protective and restructuring effects on the skin when applied topically.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003ePatients using chicory root extract experienced minimized skin water loss and skin irritation compared to a control group during the trial.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eTurmeric root extract\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e appears to be another effective botanical ingredient in Tula’s moisturizing cream. A \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27213821\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e found it to be especially effective for patients with skin conditions, likely due to its anti-inflammatory effect. The researchers noted “early evidence” of “therapeutic benefits for skin health.”\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eTula touts the benefits of apple in their marketing to “hydrate \u0026amp; help smooth the look of fine lines and wrinkles” but we can’t find much evidence backing these statements. This formulation contains \u003c\/span\u003e\u003cb\u003eapple fruit extract\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e, but we could only find \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35048513\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eone trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e suggesting that apple fruit extract was effective for skin hydration, and the trial used concentrations much higher than would be included in Tula.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eGenerally the issue with skincare products containing tons of ingredients is that it’s near impossible to assess the efficacy of each ingredient because skincare brands never publish the dosage or concentration. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA medical study may find that green tea extract, at a concentration of 10% in a cream, is effective for skin aging when applied topically. If a skincare product contains 70 ingredients and green tea extract is one of them, this does not mean that product is necessarily effective, because the concentration of green tea extract could be 0.01%.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe first 5 ingredients in Tula Hydrating Day \u0026amp; Night Cream are: \u003c\/span\u003e\u003cb\u003ewater\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e, \u003c\/span\u003e\u003cb\u003ebutylene glycol\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e, \u003c\/span\u003e\u003cb\u003eethylhexyl palmitate\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e, \u003c\/span\u003e\u003cb\u003esqualane\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e, and \u003c\/span\u003e\u003cb\u003eglycerin\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e. Cosmetics products are required to list ingredients in order of relative dose, so we know that these ingredients are all more prominent in the formulation than the previously-referenced botanical active ingredients.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThis moisturizing cream also has some questionable filler ingredients that we’d recommend avoiding. \u003c\/span\u003e\u003cb\u003eFragrance\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is shown \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6477564\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ein medical literature\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e to have potentially harmful effects on human health, and we always recommend avoiding skincare products containing fragrance.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAnother extremely questionable ingredient in this product is \u003c\/span\u003e\u003cb\u003ebutylphenyl methylpropional\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e, also known as lilial. This is another synthetic fragrance ingredient that has been shown in a \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22940465\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e to be toxic to mitochondria and increase reactive oxygen species production. It \u003c\/span\u003e\u003ca href=\"https:\/\/www.jdsupra.com\/legalnews\/european-union-s-lilial-ban-puts-social-6324675\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ewas banned\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e in the European Union (E.U.) on March 1 of 2022 due to toxicity concerns. The E.U. has much stronger consumer protections than the U.S.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOverall we don’t recommend this product due to the safety concerns. It has a few active ingredients which may be effective for skin quality improvement, but the synthetic fragrance ingredients make it too risky of a choice in our opinion. We also believe that keeping it simple in regard to skincare formulations is more logical than using a product with 54 individual ingredients without published concentrations. Since you’re only going to be using a small amount of a moisturizing cream, you’re likely to get an incredibly tiny dose of each of the 54 ingredients.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eTula Sunscreen Review\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Tula_Sunscreen_Ingredients_480x480.png?v=1648788450\" alt=\"Tula sunscreen ingredients\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAnother one of Tula’s most popular products is their sunscreen, called Daily Sunscreen Gel Broad Spectrum SPF 30. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThis is a chemical rather than a physical sunscreen, and we discussed why chemical sunscreens tend to be worse for human health in our recent \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/elta-md-sunscreen-review\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eElta MD sunscreen\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e review article.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eAvobenzone\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is one of the three active ingredients, and it’s been shown in a \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31016361\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical study\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e to cause obesity-inducing changes to human cells. The linked study concluded that avobenzone “functions as a metabolic disrupting obesogen.”\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eHomosalate\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is the second of the three active ingredients, and also has concerning clinical data. A \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31021040\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in the Journal of Cosmetic Dermatology in 2020 found that homosalate is cytotoxic (toxic to living cells), genotoxic (damaging to the genetic information in cells) and that it accumulates in living ecosystems.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eOctisalate\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is the final active ingredient, and this appears to be the safest of the chemical agents used to prevent UV damage in this product. There still is lacking long-term safety data on this compound in our opinion.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eClearly we would not recommend Tula’s sunscreen due to the inclusion of two chemical sunscreen ingredients which we find to be potentially harmful to human health.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe only recommend physical sunscreen which is non-toxic and doesn’t pose the same risks of endocrine disruption as some of the chemicals highlighted in this product.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eTula Eye Balm Review\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe final Tula product we’ll review is their eye balm, called Glow \u0026amp; Get It. It’s another one of their best-selling products.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eEven though the skin around the eyes is some of the most thin and sensitive skin on the body, Tula includes artificial dyes in this product which we find to be totally unacceptable from a risk perspective.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eBlue 1\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is one of the dyes in Tula’s eye balm, and \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23026007\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eis proven\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e in medical research to cause hypersensitivity reactions in some patients, so applying it near the eyes is unsafe in our opinion.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eYellow 5\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is the other dye used in this product, and was found in the same medical review of food dyes linked above to be frequently contaminated with carcinogens (cancer-causing compounds), to cause hypersensitivity reactions, and to be genotoxic.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThere is no need to review other ingredients in this formulation due to the inclusion of synthetic dye.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe have never reviewed a cosmetic product to date that included synthetic dye, and to include it in an eye balm shows a total lack of regard for consumer safety in our opinion.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe strongly recommend avoiding this product.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eConclusion\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eTula is a brand based on an interesting premise, but they sell skincare products with formulations we find to be a risk to consumer health.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe do believe that the trend of skincare products containing topical probiotics will increase, as more research emerges about which strains of probiotics are the most effective for anti-aging and skin quality improvements.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe were unable to identify any effective probiotic ingredients in Tula products, and the one reviewed Tula product which did contain probiotics noted that there were no live cultures in the product, effectively contradicting their marketing message and suggesting there are not, in fact, any probiotics in the product.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe recommend avoiding this brand entirely. Their formulators appear either incompetent or in disregard of consumer wellbeing. The fact that they include artificial dyes with proven hypersensitivity and toxicity risks in an eye product is a big enough red flag to avoid the brand entirely.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eSave your money and find a skincare formulation with a clean and simple formulation instead of one with 53 ingredients, many of which we believe are likely to have no beneficial effects.\u003c\/span\u003e\u003c\/p\u003e","blog_id":49281925193,"author":"Calloway Cook","user_id":26601750601,"published_at":"2022-04-01T10:30:35-04:00","updated_at":"2022-10-03T19:31:56-04:00","summary_html":"We review the ingredients in some of probiotic skincare brand Tula’s most popular products based on published medical research to determine if they’re effective or a waste of money. We highlight some safety issues we find concerning with the brand.","template_suffix":"","handle":"tula-skincare-review","tags":"_related:probiotics, _related:skincare"}

Tula Skincare Review: Do Probiotics Improve Skin?

Tula Skincare Review: Do Probiotics Improve Skin?


| |
Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.
| |
Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.


Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.

Tula is a cosmetics brand with an interesting premise: that topically-applied probiotics can improve skin quality. Their founder is a dermatologist named Dr. Roshini Raj, and the brand sells products for acne, anti-aging, dark spots and oily skin.

In this article we’ll review the ingredients in some of Tula’s most popular products based on published medical research to determine if they’re likely to be effective at improving skin quality. We’ll also analyze whether topically-applied probiotics have generally been found effective in medical studies.

Do Topical Probiotics Work?

The skin naturally has a variety of up to 1,000 healthy bacteria, referred to as the skin microbiome. When we refer to the “microbiome,” we’re typically referring to the bacteria in our gut, but we coexist with beneficial bacteria in the skin too.

Medical research has found that topically-applied probiotics can have a positive effect on inflammatory skin conditions. A 2022 review published in the Pharmaceutics journal found that topical probiotics have demonstrated positive outcomes for a wide variety of skin conditions: acne, rosacea, psoriasis and dandruff to name a few.

There’s also some early research that topical probiotics may be effective for anti-aging. A clinical trial from 2020 found that a topical probiotic called Nitrosomonas eutropha reduced the appearance of wrinkles.

Most of the research on topical probiotics is very recent. It looks promising, but we believe it’s too early to conclusively state that topical probiotics are effective. It’s definitely too early, in our opinion, to state that topical probiotics are effective for anti-aging.

We need more medical studies to determine which topical probiotic strains are effective for which skin conditions and/or aging skin. Just because one probiotic strain is effective doesn’t mean all are, because every strain has unique effects.

Tula Moisturizing Cream Review

Tula moisturizing cream ingredients

Tula’s best-selling product is their moisturizing cream, called Hydrating Day & Night Cream. The brand claims it can provide “all day hydration” and “revive the appearance of dull and tired skin.” There’s also a claimed anti-aging effect.

This cream has 54 individual ingredients which seems excessive for a basic moisturizing product. 

The product page advertises the inclusion of peptides, but we don’t see any peptides in the full ingredients list, which is quite strange.

The product page also advertises “probiotic extracts,” but we only identify one single probiotic extract on the ingredients list: Bifida Ferment Lysate. We were able to locate one medical trial proving that this ingredient had a beneficial impact on reactive skin, at a concentration of 10%.

There doesn’t appear to be any medical evidence that this probiotic is effective for skin hydration or anti-aging, and Tula doesn’t publish the concentration of this ingredient in their formulation, so we have no reason to believe it’s effective.

There’s also the extremely confusing statement that the product “does not contain live cultures.” Probiotics, definitionally, are live cultures. So Tula is marketing this cream as a probiotic cream but also noting that there are no live probiotics in the formulation.

Chicory root extract is another active ingredient in Tula’s moisturizer, and this does appear to be an effective ingredient. A recent medical trial published in the Journal of Dermatological Treatment found that this botanical compound showed protective and restructuring effects on the skin when applied topically.

Patients using chicory root extract experienced minimized skin water loss and skin irritation compared to a control group during the trial.

Turmeric root extract appears to be another effective botanical ingredient in Tula’s moisturizing cream. A medical review found it to be especially effective for patients with skin conditions, likely due to its anti-inflammatory effect. The researchers noted “early evidence” of “therapeutic benefits for skin health.”

Tula touts the benefits of apple in their marketing to “hydrate & help smooth the look of fine lines and wrinkles” but we can’t find much evidence backing these statements. This formulation contains apple fruit extract, but we could only find one trial suggesting that apple fruit extract was effective for skin hydration, and the trial used concentrations much higher than would be included in Tula.

Generally the issue with skincare products containing tons of ingredients is that it’s near impossible to assess the efficacy of each ingredient because skincare brands never publish the dosage or concentration. 

A medical study may find that green tea extract, at a concentration of 10% in a cream, is effective for skin aging when applied topically. If a skincare product contains 70 ingredients and green tea extract is one of them, this does not mean that product is necessarily effective, because the concentration of green tea extract could be 0.01%.

The first 5 ingredients in Tula Hydrating Day & Night Cream are: water, butylene glycol, ethylhexyl palmitate, squalane, and glycerin. Cosmetics products are required to list ingredients in order of relative dose, so we know that these ingredients are all more prominent in the formulation than the previously-referenced botanical active ingredients.

This moisturizing cream also has some questionable filler ingredients that we’d recommend avoiding. Fragrance is shown in medical literature to have potentially harmful effects on human health, and we always recommend avoiding skincare products containing fragrance.

Another extremely questionable ingredient in this product is butylphenyl methylpropional, also known as lilial. This is another synthetic fragrance ingredient that has been shown in a medical trial to be toxic to mitochondria and increase reactive oxygen species production. It was banned in the European Union (E.U.) on March 1 of 2022 due to toxicity concerns. The E.U. has much stronger consumer protections than the U.S.

Overall we don’t recommend this product due to the safety concerns. It has a few active ingredients which may be effective for skin quality improvement, but the synthetic fragrance ingredients make it too risky of a choice in our opinion. We also believe that keeping it simple in regard to skincare formulations is more logical than using a product with 54 individual ingredients without published concentrations. Since you’re only going to be using a small amount of a moisturizing cream, you’re likely to get an incredibly tiny dose of each of the 54 ingredients.

Tula Sunscreen Review

Tula sunscreen ingredients

Another one of Tula’s most popular products is their sunscreen, called Daily Sunscreen Gel Broad Spectrum SPF 30. 

This is a chemical rather than a physical sunscreen, and we discussed why chemical sunscreens tend to be worse for human health in our recent Elta MD sunscreen review article.

Avobenzone is one of the three active ingredients, and it’s been shown in a medical study to cause obesity-inducing changes to human cells. The linked study concluded that avobenzone “functions as a metabolic disrupting obesogen.”

Homosalate is the second of the three active ingredients, and also has concerning clinical data. A medical trial published in the Journal of Cosmetic Dermatology in 2020 found that homosalate is cytotoxic (toxic to living cells), genotoxic (damaging to the genetic information in cells) and that it accumulates in living ecosystems.

Octisalate is the final active ingredient, and this appears to be the safest of the chemical agents used to prevent UV damage in this product. There still is lacking long-term safety data on this compound in our opinion.

Clearly we would not recommend Tula’s sunscreen due to the inclusion of two chemical sunscreen ingredients which we find to be potentially harmful to human health.

We only recommend physical sunscreen which is non-toxic and doesn’t pose the same risks of endocrine disruption as some of the chemicals highlighted in this product.

Tula Eye Balm Review

The final Tula product we’ll review is their eye balm, called Glow & Get It. It’s another one of their best-selling products.

Even though the skin around the eyes is some of the most thin and sensitive skin on the body, Tula includes artificial dyes in this product which we find to be totally unacceptable from a risk perspective.

Blue 1 is one of the dyes in Tula’s eye balm, and is proven in medical research to cause hypersensitivity reactions in some patients, so applying it near the eyes is unsafe in our opinion.

Yellow 5 is the other dye used in this product, and was found in the same medical review of food dyes linked above to be frequently contaminated with carcinogens (cancer-causing compounds), to cause hypersensitivity reactions, and to be genotoxic.

There is no need to review other ingredients in this formulation due to the inclusion of synthetic dye.

We have never reviewed a cosmetic product to date that included synthetic dye, and to include it in an eye balm shows a total lack of regard for consumer safety in our opinion.

We strongly recommend avoiding this product.

Get our most popular articles straight to your inbox
Stay up-to-date on our research reviews

Conclusion

Tula is a brand based on an interesting premise, but they sell skincare products with formulations we find to be a risk to consumer health.

We do believe that the trend of skincare products containing topical probiotics will increase, as more research emerges about which strains of probiotics are the most effective for anti-aging and skin quality improvements.

We were unable to identify any effective probiotic ingredients in Tula products, and the one reviewed Tula product which did contain probiotics noted that there were no live cultures in the product, effectively contradicting their marketing message and suggesting there are not, in fact, any probiotics in the product.

We recommend avoiding this brand entirely. Their formulators appear either incompetent or in disregard of consumer wellbeing. The fact that they include artificial dyes with proven hypersensitivity and toxicity risks in an eye product is a big enough red flag to avoid the brand entirely.

Save your money and find a skincare formulation with a clean and simple formulation instead of one with 53 ingredients, many of which we believe are likely to have no beneficial effects.




Illuminate Labs is a proud member of

Liquid error: Could not find asset snippets/search-bar.liquid