EnhanceRx is a male enhancement supplement that’s primarily sold online. The brand claims their product can cause “Stronger and Healthier Erections” and “Improved Sexual Drive” amongst other claimed benefits.

But does EnhanceRx contain ingredients proven to have these effects in research studies, or are these just marketing claims? Are the ingredients effectively dosed? Will EnhanceRx cause side effects? And does the brand have research to support their statements about the superiority of their supplement?

In this article we’ll answer all of these questions and more as we analyze the ingredients in EnhanceRx based on medical studies to give our take on whether the supplement is likely to be effective for male enhancement, or if it’s a waste of money.

We’ll discuss side effects, share our concerns about some of the claims made by the manufacturer, and share our concerns about some of the ingredient doses.

Ingredient Analysis

The ingredients in EnhanceRx are shown above.

Niacin is a B-vitamin and we can’t find any clinical evidence it improves sexual function in men.

Zinc was shown to improve testosterone (T) status in men with low testosterone in a medical review published in the Aging Male journal, but the treatment dose was 50 milligrams (mg), while only 15 mg of zinc is contained in each dose of EnhanceRx.

The remaining active ingredients are mostly herbs, and are contained in a proprietary blend totalling 515 mg, or 47 mg per ingredient.

Some of these botanical ingredients have research backing for male health and sexual function, but we can’t find any evidence they’re effective at such a low average ingredient dose.

Here are a few examples:

Tribulus terrestris was shown in a 2017 clinical trial to improve sexual function in men with erectile dysfunction (ED), but the format used was an extract (which is more potent than the raw plant material in EnhanceRx), and the daily dose was over 1,000 mg (which is more than 20x the average ingredient dose in EnhanceRx’s prop blend).

Korean red ginseng is an effective natural erectile dysfunction (ED) treatment according to a meta-study published in the British Journal of Clinical Pharmacology, but the lowest dose used in any of the analyzed trials is more than 10x the average ingredient dose in EnhanceRx’s blend.

Overall, we consider EnhanceRx potentially effective for improving libido because it does contain some research-backed ingredients. However, we have concerns about the doses of those ingredients.

We’re unable to identify any active ingredient in EnhanceRx that’s clinically shown to be effective at the dose used in the supplement.

The good news about this supplement is that it has no unhealthy additive ingredients.

Questionable Health Claims

There are a number of questionable health claims on the EnhanceRx website.

The brand claims that their supplement has a 97% success rate:

There is no definition for how “success” is achieved, and there is no citation for this claim. We can’t find any clinical trials on EnhanceRx, so we don’t understand how the brand is making such a specific claim of efficacy.

EnhanceRx also suggests that their supplement improves testosterone levels in men in the graphic below:

Again, we don’t understand how EnhanceRx is making this claim if their supplement hasn’t been clinically shown to improve T levels.

We recommend that consumers be extremely cautious when considering a purchase from a brand that makes uncited health claims.

But does EnhanceRx cause side effects? We’ll answer that question in the next section. 

Does EnhanceRx Cause Side Effects?

It’s challenging to assess the risk of side effects for supplements that have not been clinically tested. However, we can make an educated guess based on the ingredients.

We do not consider EnhanceRx likely to cause side effects in otherwise healthy adults. The supplement is mostly composed of well-studied herbs and vitamins.

None of the active ingredients are included at a high enough dose to give us concern.

Maca is the only ingredient that we identify as a potential cause of mild side effects. As we discussed in our Semenax review article, raw maca is indigestible, much like raw potato starch.

We would recommend supplements containing the gelatinized form of maca (which is digestible) over supplements containing raw maca.

There is no discussion of whether or not EnhanceRx causes side effects on the brand’s website at the time of publishing this article.

Our Clean Men's Health Picks

Bulletproof Magnesium is our top testosterone support pick, because magnesium is a mineral that is clinically shown to increase free and total testosterone in athletes and in sedentary individuals.

Bulletproof Magnesium costs under $17 at the time of updating this article.

Momentous Tongkat Ali is our top herbal testosterone support pick, and costs under $20 at the time of updating this article.

Tongkat ali's effects on testosterone were reviewed in a 2022 meta-study, and the researchers concluded that "A significant improvement in total testosterone levels after [tongkat ali] treatment was mostly reported in both healthy volunteers and hypogonadal men."

Panax ginseng was shown in a clinical trial published in The Journal of Urology to increase erectile function scores were "significantly" compared to participants taking placebo pills.

Illuminate Labs sells a Panax Ginseng Extract supplement which is third-party tested, and costs only $15 on a subscription basis.

EnhanceRx Pros and Cons

Here are the pros and cons of EnhanceRx in our opinion:

Pros:

• Safe active ingredients
• May improve sex drive
• Safe inactive ingredients

Cons:

• Doesn’t appear to be clinically tested
• Relatively low doses in prop blend
• Brand makes questionable health claims
• Contains raw maca
• Brand fails to discuss side effects of the supplement on their website.
• Expensive

Conclusion

We can’t find any evidence that EnhanceRx is more effective than any other male enhancement product on the market.

We do consider EnhanceRx a safer supplement than most male enhancement supplements, because it uses well-studied botanical ingredients and vitamins. 

The average ingredient dose in the prop blend is low enough to give us concern about efficacy. Most of the clinical trials we could find on the included ingredients used doses many times higher than the doses in this blend.

We do not consider EnhanceRx likely to cause side effects in otherwise healthy adults, although raw maca can cause mild indigestion.

There are a number of questionable and uncited health claims on the EnhanceRx website. We urge the brand to either remove these claims from their site, or support for them.