Dermelect Review: Does Overnight Anti-Aging Work?

Dermelect Review: Does Overnight Anti-Aging Work?

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Dermelect is a fast-growing skincare brand that's priced in the mid-range of the market. The brand has positive reviews in major publications like The New York Times and InStyle.

But does Dermelect use ingredients shown in clinical studies to improve skin quality? Does the brand use any unhealthy additives? How do real users rate and describe the effects of this product line? And which retailer sells Dermalect for the best price?

In this article we'll answer all of these questions and more, as we analyze the ingredients in two of Dermelect's most popular products (Flawless Bakuchiol Treatment and Beauty Sleep Serum) to give our take on whether or not they're likely to be effective.

We'll also feature unsponsored customer reviews, and feature a cost comparison to show which retailer sells Dermelect for the best price.

Ingredient Analysis — Bakuchiol Treatment

Dermelect Flawless Bakuchiol Treatment ingredients

The ingredients in Dermelect Flawless Bakuchiol Treatment are shown above.

This product is used as a retinol alternative to promote a "balanced complexion."

This formulation contains several active ingredients which are clinically shown to improve skin quality.

Bakuchiol was shown to possess anti-aging effects in a systematic review published in the Journal of Cosmetic Dermatology.

Ginger extract is clinically shown to have anti-inflammatory effects when applied topically.

Pelargonium graveolens flower oil was shown in a 2006 medical review to have "antibacterial and antifungal activity" when applied topically, which suggests it may have anti-acne effects.

This formulation contains some inactive ingredients we recommend avoiding.

Ethylhexylglycerin and phenoxyethanol are synthetic preservatives that have a greater toxic effect when used in combination than in isolation, as we documented in our review of another skincare line called VouPre.

Benzyl alcohol and potassium sorbate are two other synthetic preservatives, and the use of four separate synthetic preservatives in one serum is not something we'd recommend.

Overall, we consider Flawless Bakuchiol Treatment likely to have an anti-aging effect. However, we don't currently recommend this product due to the preservatives discussed above.

Real People Try Dermelect

A YouTube creator named "PENN.SMITH.SKINCARE" claims that Dermelect's face and neck products are superior in an unsponsored review video with over 40,000 views:

A TikTok creator named "thenatashaann" reviewed Dermelect products in a series focusing on dry and sensitive skin:

@thenatashaann Giving a little TLC to my dry sensitive by trying out @Dermelect skincare 🤗 #dermelect #dermelectskin #dermelectskincare #dryskinremedies #sensitiveskinsolutions #guwm ♬ original sound - natasha bernfeld

Ingredient Analysis — Sleep Serum

Dermelect Beauty Sleep Serum ingredients

The ingredients in Dermelect Beauty Sleep Serum are shown above.

This product is used for anti-aging, and to "perfect the skin while you sleep."

There are several anti-aging active ingredients in this formulation.

Ascorbic acid, better known as vitamin C, is clinically shown to significantly reduce wrinkles when applied topically.

Echinacea purpurea extract was described as containing "many beneficial constituents for protection of skin" in a medical review published in the International Journal of Cosmetic Science.

Aloe barbadensis leaf extract is clinically shown to have skin-healing and hydrating properties, as we documented in our Versed Skincare reviews article.

Phenoxyethanol and ethylhexylglycerin are inactive ingredients we recommend avoiding, for reasons explained in the previous Ingredient Analysis section.

Overall, we consider Dermelect Sleep Serum likely to have anti-aging effects. However, we don't currently recommend it due to the combination of preservatives used.

Our Clean Skincare Picks

There are skincare products containing ingredients shown in clinical trials to be effective for reducing wrinkles and improving skin quality.

Annie Mak Vitamin C Serum is our top anti-aging serum.

It contains hyaluronic acid which was described as a "skin-rejuvenating biomedicine" in a medical review due to its ability to reduce wrinkles and signs of facial aging.

HYDRAGLOW by CLEARSTEM is our top moisturizer pick.

It features bakuchiol as an active ingredient which was described in a 2014 clinical trial as "clinically proven to have anti-aging effects." 

Bulletproof Collagen Powder is our top skin supplement.

Collagen supplementation was shown in a medical review published in the Journal of Drugs in Dermatology to reduce visible signs of skin aging as well as improve skin elasticity and skin hydration.

All of the products recommended in this section are entirely free of ingredients that we consider to be unhealthy.

Real Customers Rate Dermelect

Amazon is a better resource for honest customer reviews than a brand's website in our opinion. 

Dermelect Sleep Serum has been reviewed over 450 times on Amazon at the time of publishing this article, with an average customer review rating of 4.5 out of 5 stars.

A top positive review from a verified purchaser is written by a user named "Nidhi" who gave the product a 5/5 rating, and who claims it's effective for a variety of skincare conditions:

"Overall, this serum is a great addition to any skincare routine, particularly for those looking to address multiple skin concerns effectively."

A top negative review from a verified purchaser comes from a user named "Amy Sullivan" who gave the product a 1/5 rating, and who claims it's inauthentic:

"Ivory ordered this product because I loved it so much however the next time I received it through Amazon, it smell different, brought my skin and left a sticky residue on my skin. I will not be ordering this again through Amazon."

Dermelect currently has an average review rating of 5 out of 5 stars on Facebook.

Dermelect Sleep Serum currently has an average review rating of 4.5 out of 5 stars on Google.

Where to Get the Best Price

Dermelect is sold at a variety of online retailers.

Here's a price breakdown for a one-time purchase of the two Dermelect products reviewed in this article:

Bakuchiol Treatment

Brand website: $59 (free shipping, link)

Walmart: $59 (free shipping, link)

Amazon: $59 (free shipping, link to official Amazon listing)

QVC: $46.98 (plus $3.50 shipping, link)

Sleep Serum

Brand website: $45 (free shipping, link)

QVC: $35.98 (plus shipping, link)

Amazon: $35.98 (free shipping, link to official Amazon listing)

The price of Dermelect products is over 20% cheaper at select retailers at the time of publishing this article.

Dermelect Pros and Cons

Here are the pros and cons of Dermelect in our opinion:


  • Fair prices
  • Bakuchiol Treatment should improve skin complexion
  • Sleep Serum should have anti-aging effects
  • Highly positive online customer reviews
  • Low threshold for free shipping on brand's website


  • Doesn't appear to be clinically tested
  • Phenoxyethanol and ethylhexylglycerin used in combination
  • Bakuchiol Treatment contains four synthetic preservatives
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Dermelect skincare products are fairly priced and well-formulated from an efficacy perspective.

Flawless Bakuchiol Treatment contains a variety of active ingredients that should support the label claims through different mechanisms of action.

Sleep Serum contains several anti-aging and hydrating ingredients.

We don't currently recommend either product due to the inclusion of a synthetic preservative combination that may be toxic.

Dermelect has highly positive customer reviews across all platforms we surveyed while publishing this article.

At the time of publishing this article, QVC and Amazon have the best prices on Dermelect products, depending on the product.