MENO is a dietary supplement used to treat menopause symptoms sold by the O Positive brand. It comes in gummy and capsule form, and the brand claims that this supplement contains “clinically-studied ingredients” that can help relieve hot flashes, night sweats and more.
But does MENO contain research-backed ingredients for relieving menopausal symptoms? Does it contain any unhealthy ingredients? Does it cause side effects? And is MENO better or worse than popular menopause supplements like Stunning After 40?
In this article we’ll answer all of these questions and more, as we analyze the ingredients in MENO to give our take on whether or not this supplement is likely to be effective for relieving menopausal symptoms, and whether or not it's healthy.
We'll explain why we consider the MENO capsule formulation to be healthier than the gummy formulation, and compare MENO to other popular menopause supplements to pick our winners.
Key takeaways:
- Likely to reduce hot flashes based on active ingredients
- Contains inactive ingredients we consider unhealthy
- We do not currently recommend MENO
Ingredient Analysis
The active ingredients in MENO Vitamins are shown below:

This supplement does contain research-backed ingredients for relieving menopausal symptoms.
Vitamin B6 intake is inversely associated with severity of hot flashes according to a clinical trial published in the Climacteric journal. This means that higher vitamin B6 intake tends to cause less severe hot flashes.
Vitamin D3 makes sense for a menopause supplement, because low levels of vitamin D were associated with severity of hot flashes according to a 2020 medical review.
Ashwagandha is clinically shown to improve libido in women, as we discussed in our review of women’s health supplement Hormone Harmony.
Chasteberry extract was described in a medical review published in the Complementary Therapies in Medicine journal as “confirmed to be effective in the reduction of PMS symptoms."
Black cohosh may relieve menopausal symptoms according to a 2022 medical review, although the researchers note that most studies used an extracted version of this plant, while MENO contains the raw version (which is less concentrated and potent).
It’s rare that we find clinical research backing every active ingredient in a supplement formulation, so we commend O Positive from an efficacy perspective.
The inactive ingredients in MENO are shown below (we apologize for the low quality of this image, this is the image published by the brand):

Natural colors is a questionable additive in our opinion because it fails to document which specific chemical compounds are used.
Titanium dioxide is banned as a food additive in the EU, according to the USDA.
This ingredient is also the subject of a lawsuit involving the candy brand Skittles, where plaintiffs describe it as a “known toxin,” according to NPR.
Overall, we consider MENO Vitamins highly likely to be effective for the relief of menopausal symptoms, given that this supplement contains research-backed ingredients at effective doses.
We don’t currently recommend MENO due to the two inactive ingredients highlighted above.
The gummy supplement is free of titanium dioxide, but contains added sugar (which is clinically shown to be associated with weight gain when consumed in excess), and citric acid (which is clinically shown to cause inflammatory reactions in some individuals).
But how do real users rate and describe the effects of this supplement? We’ll feature some unsponsored customer reviews in the next section of this article.
Do MENO Vitamins Cause Side Effects?
MENO doesn’t appear to have been studied in any clinical trials, which makes it challenging to say whether or not this supplement will cause side effects.
However, we can make an educated guess based on its ingredients.
Black cohosh may cause side effects such as dizziness and vomiting according to a 2022 medical review, but this is described as an uncommon side effect, and the dose in MENO is quite modest.
There is no mention of side effects on the product page of the brand’s website.
Overall, we consider MENO Vitamins unlikely to cause side effects in otherwise healthy adults, because its active ingredients have favorable safety profiles.
It’s always best to check with a doctor before taking any new supplement just to be safe.
MENO Vitamins vs. Popular Menopause Supps
Here's how MENO compares to other popular menopause supplements in terms of potential effectiveness and healthiness, in our opinion:
Stunning After 40
Primarily a weight loss supplement, this menopausal brand contains probiotic strains clinically shown to support weight loss.
However, we consider MENO more likely to relieve menopausal symptoms.
Winner: MENO Vitamins
Amberen
Contains active ingredients that are clinically shown to increase estradiol in the body, which should relieve menopause symptoms.
As we documented in our Amberen review article, the supplement only contains one questionable inactive ingredient (as opposed to two in MENO), so we give it a slight edge in regard to healthiness.
Winner: Amberen
Equelle
Contains research-backed active ingredients and no ingredients we consider unhealthy.
Winner: Equelle
Our Clean Menopause Support Picks

Illuminate Labs Panax Ginseng Extract is our top menopause support pick.
A meta-study on natural products for treating female sexual dysfunction found that panax ginseng was effective for improving sexual arousal and sexual desire in women.
Pique Japanese Sencha Green Tea is our top menopause health support pick.
Green tea is clinically shown to have mood-boosting effects and also clinically shown to support optimal cholesterol and glucose levels in menopausal women.
Both of the products recommended in this section are free of ingredients that we consider to be unhealthy.
MENO Vitamins Pros and Cons
Pros:
- All active ingredients have research backing
- Likely to relieve menopausal symptoms
- Likely to be especially effective against hot flashes
- Hormone-free
- Unlikely to cause side effects
- Mostly positive online customer reviews
Cons:
- Doesn’t appear clinically tested
- Contains titanium dioxide
- Contains “natural colors”
- Gummies contain citric acid
- Gummies contain added sugar