{"id":606021910834,"title":"Agency Skincare Review: Personalized Anti-Aging?","created_at":"2023-08-08T23:28:45-04:00","body_html":"\u003cscript type=\"application\/ld+json\"\u003e\/\/ \u003c![CDATA[\n{\n \"@context\": \"https:\/\/schema.org\",\n \"@type\": \"Article\",\n \"headline\": \"Agency Skincare Review: Personalized Anti-Aging?\",\n \"keywords\": \"agency skincare, agency skincare review, agency skincare reviews, agency skincare before and after\",\n \"description\": \"Our research team and dermatologist analyze the ingredients in Agency Skincare's custom formulations based on medical studies to give our take on whether they're likely to have an anti-aging effect or if they're a waste of money. We feature unsponsored before-and-afters.\",\n \"url\": \"https:\/\/illuminatelabs.org\/blogs\/health\/agency-skincare-review\",\n\"author\": {\n \"@type\": \"Person\",\n \"name\": \"Calloway Cook\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/calloway-cook\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/calloway-cook\/\",\n \"jobTitle\": \"President\",\n \"knowsAbout\": \"entrepreneurship, dietary supplements, herbal supplements, eCommerce, medical research\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": \"S.I. Newhouse School of Public Communications at Syracuse University\"\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"editor\": {\n \"@type\": \"Person\",\n \"name\": \"Beth Lertzman\",\n \"honorificSuffix\": \"M.D.\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/beth-lertzman\",\n \"sameAs\": [\n \"https:\/\/www.linkedin.com\/in\/beth-lertzman-md-856619118\/\",\n \"https:\/\/health.usnews.com\/doctors\/beth-lertzman-517042\"\n ],\n \"jobTitle\": \"Dermatology Reviewer\",\n \"knowsAbout\": \"skincare, collagen, cosmetics, surgery, wrinkles, ingredients, formulation, clinical trials, clinical research\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"University of Delaware\",\n \"Drexel University College of Medicine\",\n \"University of Rochester\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n },\n\"image\": {\n\"@type\": \"ImageObject\",\n\"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Agency_Skincare_Thumbnail.png?v=1691552103\",\n\"width\": \"3264\",\n\"height\": \"3264\"\n},\n\"citation\": [\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20977120\/\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9112391\/\",\n\"https:\/\/illuminatelabs.org\/blogs\/health\/ambi-fade-cream-review\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8929036\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31788813\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16154914\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/2472232\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32387382\/\",\n\"https:\/\/illuminatelabs.org\/blogs\/health\/reverse-health-review\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5903487\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30287361\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24471735\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30681787\/\"\n],\n\"mentions\": [{\n \"@type\": \"Thing\",\n \"name\": \"tretinoin\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"niacinamide\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"polyacrylamide\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"BHT\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"data security\"\n },\n {\n \"@type\": \"Brand\",\n \"name\": \"Abbey Yung\"\n }\n],\n\"datePublished\": \"2023-08-08\",\n\"copyrightHolder\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n},\n\"publisher\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\",\n \"url\": \"https:\/\/illuminatelabs.org\/\",\n \"description\": \"Illuminate Labs is the most transparent supplement company in the U.S., and is a leading publisher of research-based health information.\",\n \"knowsAbout\": \"supplements, science, nutrition, exercise, health, medication, pharmaceutical, wellness, diet, weight loss, medical research\",\n \"publishingPrinciples\": \"https:\/\/illuminatelabs.org\/pages\/editorial-guidelines\",\n \"memberOf\": [\n {\n \"@type\": \"Organization\",\n \"name\": \"U.S. Chamber of Commerce\",\n \"url\": \"https:\/\/www.uschamber.com\/\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Certified B Corp\",\n \"url\": \"https:\/\/www.bcorporation.net\/en-us\/\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Natural Products Association\",\n \"url\": \"https:\/\/www.npanational.org\/\"\n }\n ],\n \"logo\": {\n \"@type\": \"ImageObject\",\n \"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Illuminate_Labs_Favicon_48x48_7595c3cc-e27b-47b8-a4fe-edcc7ed9b29a.png?v=1666502785\", \n \"width\": 48,\n \"height\": 48\n},\n \"foundingDate\": \"2019-01-30\",\n \"sameAs\": [\n \"https:\/\/www.instagram.com\/illuminatelabs\",\n \"https:\/\/twitter.com\/illuminatelabs\",\n \"https:\/\/www.linkedin.com\/company\/illuminate-labs-supplements\",\n \"https:\/\/www.youtube.com\/channel\/UCpgSJAsIPb-fZ25djtTxBEA\"\n ]\n }\n}\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Agency_Skincare_Review_Article_Header_Image_Optimized.png?v=1691551611\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cspan class=\"dc\"\u003eA\u003c\/span\u003egency Skincare is a customized skincare brand led by dermatologist recommendations. The brand describes their offerings as “elevated essentials for your skin’s daily needs,” and suggests they have an anti-aging effect.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eBut does Agency Skincare use research-backed ingredients for anti-aging, or are these just marketing claims? Does the brand use any questionable additive ingredients? Is personalized skincare actually better than off-the-shelf cosmetic products? And how do real users rate and describe the effects of Agency Skincare?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn this article, we’ll answer all of these questions and more as we analyze the ingredients in Agency Skincare based on medical studies to give our take on whether the brand is likely to be effective, or if it’s a waste of money.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe’ll share our thoughts on personalized skincare as a whole and whether it’s a gimmick, and feature unsponsored customer reviews of Agency Skincare.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eIngredient Analysis\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe input test answers into the Agency Skincare website health questionnaire indicating our goal was to fight wrinkles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe active ingredients prescribed are shown below:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg alt=\"Agency Skincare active ingredients\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Agency_Skincare_Active_Ingredients_Optimized.png?v=1691551845\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eAzelaic acid\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is typically used for acne, but may also have an anti-aging effect. A 2010 \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20977120\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e states that “Topical bleaching agents such as hydroquinone, kojic acid and azelaic acid can reduce signs of aging.”\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eTretinoin\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is a derivative of vitamin A that appears highly effective against wrinkles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9112391\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in the \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eInternational Journal of Women’s Dermatology\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e found that topical tretinoin was effective against wrinkles in all clinical studies analyzed, and concluded that the treatment “could significantly improve wrinkling.”\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eNiacinamide\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is clinically shown to reduce the visible appearance of wrinkles, as we documented in our review of \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/ambi-fade-cream-review\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eAmbi Fade Cream\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eDexpanethnol\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e promotes cell growth according to a 2021 \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8929036\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e, which suggests it may also be effective against aging.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eTranexamic acid\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e was shown to prevent photoaging in a 2020 \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31788813\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eanimal study\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e, which is a weaker standard of evidence than human studies.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe consider all of the active ingredients in Agency Skincare’s anti-aging formulation to have significant research backing.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\u0026gt;However, the brand also uses some questionable inactive ingredients as shown in the list below:\u0026lt;\/span\u0026gt;\u0026lt;\/p\u0026gt;\n\u0026lt;p\u0026gt;\u0026lt;span style=\" font-weight:\u003e\u003cimg alt=\"Agency Skincare inactive ingredients\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Agency_Skincare_Inactive_Ingredients_Optimized.png?v=1691551824\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePolyacrylamide\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is a stabilizer described as a “demonstrated neurotoxin in humans” in a 2005 \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16154914\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e. This review does not prove that this ingredient is absorbed through the skin, but we feel this information is worth highlighting.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eBHT\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is a synthetic preservative that breaks down into BHTOOH, which was described as a tumor promoter in a \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/2472232\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in the \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eCarcinogenesis\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e journal.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePhenoxyethanol\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is another synthetic preservative that’s \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32387382\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinically shown\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e to be toxic to human cells. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOverall, we consider Agency Skincare highly likely to have an anti-aging effect given its prescription-strength active ingredients. We don’t currently recommend this product due to the inactive ingredients highlighted above.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eBut how do real users rate and describe the effects of Agency Skincare? We’ll feature some unsponsored customer reviews in the next section.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eReal People Try Agency Skincare\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA TikTok creator named Orah Lasko shared her experience using an Agency Skincare product including before-and-after images:\u003c\/span\u003e\u003c\/p\u003e\n\u003cblockquote style=\"max-width: 325px; min-width: 325px;\" data-video-id=\"7174625180507966763\" cite=\"https:\/\/www.tiktok.com\/@orahlasko\/video\/7174625180507966763\" class=\"tiktok-embed\"\u003e\n\u003csection\u003e\u003ca href=\"https:\/\/www.tiktok.com\/@orahlasko?refer=embed\" title=\"@orahlasko\" target=\"_blank\"\u003e@orahlasko\u003c\/a\u003e The Tretinoin glow up is real @Agency Skincare \u003ca href=\"https:\/\/www.tiktok.com\/tag\/tretinoin?refer=embed\" title=\"tretinoin\" target=\"_blank\"\u003e#tretinoin\u003c\/a\u003e \u003ca href=\"https:\/\/www.tiktok.com\/tag\/skincare?refer=embed\" title=\"skincare\" target=\"_blank\"\u003e#skincare\u003c\/a\u003e \u003ca href=\"https:\/\/www.tiktok.com\/tag\/skincareroutine?refer=embed\" title=\"skincareroutine\" target=\"_blank\"\u003e#skincareroutine\u003c\/a\u003e \u003ca href=\"https:\/\/www.tiktok.com\/music\/Love-Yourself-222449567974359040?refer=embed\" title=\"♬ Love Yourself - Jasmine Thompson\" target=\"_blank\"\u003e♬ Love Yourself - Jasmine Thompson\u003c\/a\u003e\u003c\/section\u003e\n\u003c\/blockquote\u003e\n\u003cscript async=\"\" src=\"https:\/\/www.tiktok.com\/embed.js\"\u003e\u003c\/script\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA TikTok creator named Mary Margaret has an unsponsored video where she explains why she considers Agency to be a more convenient option than standard prescription skincare:\u003c\/span\u003e\u003c\/p\u003e\n\u003cblockquote class=\"tiktok-embed\" cite=\"https:\/\/www.tiktok.com\/@mary_hayes\/video\/7109543030436236587\" data-video-id=\"7109543030436236587\" style=\"max-width: 325px; min-width: 325px;\"\u003e\n\u003csection\u003e\u003ca title=\"@mary_hayes\" href=\"https:\/\/www.tiktok.com\/@mary_hayes?refer=embed\" target=\"_blank\"\u003e@mary_hayes\u003c\/a\u003e Unsponsored honest review of agency’s retinol prescription service-i was gifted this but under no obligation to post this is my opinion after one month! \u003ca title=\"skincareroutine\" href=\"https:\/\/www.tiktok.com\/tag\/skincareroutine?refer=embed\" target=\"_blank\"\u003e#skincareroutine\u003c\/a\u003e \u003ca title=\"tretinoin\" href=\"https:\/\/www.tiktok.com\/tag\/tretinoin?refer=embed\" target=\"_blank\"\u003e#tretinoin\u003c\/a\u003e \u003ca title=\"tretinoinjourney\" href=\"https:\/\/www.tiktok.com\/tag\/tretinoinjourney?refer=embed\" target=\"_blank\"\u003e#tretinoinjourney\u003c\/a\u003e \u003ca title=\"agencyskincare\" href=\"https:\/\/www.tiktok.com\/tag\/agencyskincare?refer=embed\" target=\"_blank\"\u003e#agencyskincare\u003c\/a\u003e \u003ca title=\"♬ original sound - Mary Margaret\" href=\"https:\/\/www.tiktok.com\/music\/original-sound-7109542995032034091?refer=embed\" target=\"_blank\"\u003e♬ original sound - Mary Margaret\u003c\/a\u003e\u003c\/section\u003e\n\u003c\/blockquote\u003e\n\u003cscript async=\"\" src=\"https:\/\/www.tiktok.com\/embed.js\"\u003e\u003c\/script\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eIs Personalized Skincare a Gimmick?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003ePersonalized skincare is becoming more and more popular, and while we all have individual genetics and environmental constraints, we haven’t come across any convincing clinical evidence suggesting that this modality of treatment is better than standard off-the-shelf products or personalized skincare recommendations from a regular dermatologist.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThere’s also the issue of data security. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAgency’s website asks a variety of health questions including pregnancy status, gender and more. As we discussed in our \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/reverse-health-review\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eReverse Health reviews\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e article on another personalized health brand, sharing this information with an online-first healthcare provider may increase the risk of data breaches compared to an in-person provider.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIt is worth noting that personalized skincare may lead to better aging results at least in regard to sunscreen recommendations, according to a \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5903487\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in the \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eClinical, Cosmetic and Investigational Dermatology\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e journal.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eOverall, we think that personalized skincare may have benefits, but isn’t worth significantly increased cost\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e based on the current stage of research and our understanding of individual cosmetic factors.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eAgency vs. Other Personalized Skincare Brands\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA popular beauty vlogger named Abbey Yung compared four personalized skincare brands, including Agency Skincare, in a video with over 100,000 views:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ciframe title=\"YouTube video player\" src=\"https:\/\/www.youtube.com\/embed\/GzpGczgtElI\" height=\"315\" width=\"560\" allowfullscreen=\"\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" frameborder=\"0\"\u003e\u003c\/iframe\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eOur Clean Skincare Picks\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Skincare_Products_Image_Optimized.png?v=1664754145\" alt=\"\"\u003e\u003c\/p\u003e\n\u003cp\u003eThere are skincare products that contain ingredients shown in clinical trials to be effective for reducing wrinkles and improving skin quality generally.\u003c\/p\u003e\n\u003cp\u003e\u003ca rel=\"sponsored\" href=\"http:\/\/track.revoffers.com\/aff_c?offer_id=155\u0026amp;aff_id=7240\u0026amp;url_id=2077\"\u003e\u003cspan\u003eAnnie Mak Vitamin C Serum\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e is our top skin cream pick because of its effective and clean formulation. It contains \u003c\/span\u003e\u003cb\u003ehyaluronic acid\u003c\/b\u003e\u003cspan\u003e which was described as a \u003c\/span\u003e\u003cb\u003e\"skin-rejuvenating biomedicine\"\u003c\/b\u003e\u003cspan\u003e in a \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30287361\/\"\u003e\u003cspan\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e due to its ability to reduce wrinkles and signs of facial aging.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eInterested consumers can check out Annie Mak Vitamin C Serum \u003ca rel=\"sponsored\" href=\"http:\/\/track.revoffers.com\/aff_c?offer_id=155\u0026amp;aff_id=7240\u0026amp;url_id=2077\"\u003eat this link\u003c\/a\u003e to the product page on the official brand's website.\u003c\/p\u003e\n\u003cp\u003e\u003ca rel=\"sponsored\" href=\"http:\/\/track.revoffers.com\/aff_c?offer_id=159\u0026amp;aff_id=7240\u0026amp;url_id=2174\"\u003eHydraglow\u003c\/a\u003e\u003cspan\u003e \u003c\/span\u003eis our top moisturizer pick. It features\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003ebakuchiol\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eas an active ingredient which was described in a 2014 \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24471735\/\"\u003eclinical trial\u003c\/a\u003e as\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003e\"clinically proven to have anti-aging effects.\"\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eInterested consumers can check out HydraGlow\u003cspan\u003e \u003c\/span\u003e\u003ca rel=\"sponsored\" href=\"http:\/\/track.revoffers.com\/aff_c?offer_id=159\u0026amp;aff_id=7240\u0026amp;url_id=2174\"\u003eat this link\u003c\/a\u003e to the product page on the official brand's website.\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe only oral supplement we recommend for skin quality improvement is \u003c\/span\u003e\u003ca rel=\"sponsored\" href=\"https:\/\/bulletproof.fdf2.net\/c\/3271428\/1278011\/9221\"\u003e\u003cspan\u003eBulletproof Collagen Powder\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eOral \u003c\/span\u003e\u003cb\u003ecollagen\u003c\/b\u003e\u003cspan\u003e supplementation was shown in a \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30681787\/\"\u003e\u003cspan\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e published in the \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eJournal of Drugs in Dermatology\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e \u003c\/span\u003e\u003cb\u003eto improve visible signs of skin aging as well as improve skin elasticity and skin hydration\u003c\/b\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eInterested consumers can check out Bulletproof Collagen Powder \u003ca rel=\"sponsored\" href=\"https:\/\/bulletproof.fdf2.net\/c\/3271428\/1278011\/9221\"\u003eat this link\u003c\/a\u003e to the product page on the brand's official website.\u003c\/p\u003e\n\u003cp\u003eNone of the products recommended in this section contain additive ingredients that we consider questionable from a health perspective.\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003ePros and Cons of Agency Skincare\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eHere are the pros and cons of Agency Skincare in our opinion:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cb\u003ePros:\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eMore convenient than a visit to a clinic\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ePrescription-strength\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eLikely to have anti-aging effect\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eAll active ingredients have research backing\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eVery favorable online customer reviews\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ePersonalized skincare may be optimally effective\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eCons:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eContains synthetic preservatives\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eContains polyacrylamide\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eCustom, proprietary formulations don’t appear clinically tested\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eConclusion\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAgency Skincare is one of the more impressive personalized skincare brands we’ve reviewed to date on Illuminate Health.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThis brand has an anti-aging focus, and our analysis of the active ingredients used in their anti-aging product(s) suggests they will be effective. All five of the active ingredients in our custom formulation had research backing for anti-aging effects.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe don’t currently recommend Agency Skincare due to the inclusion of three inactive ingredients that may be questionable from a health perspective.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOnline customer reviews suggest that Agency is more convenient than an in-person dermatologist visit, and we would tend to agree. This company offers prescription-strength treatments from the comfort of the home.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOnline customer reviews of this brand were more favorable than other personalized skincare brands we’ve reviewed.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe have our questions about the efficacy of personalized skincare based on online questionnaires over standard dermatological treatment, but at least one medical review suggests that personalized skincare may be useful for optimizing anti-aging efforts.\u003c\/span\u003e\u003c\/p\u003e","blog_id":49281925193,"author":"Calloway Cook","user_id":26601750601,"published_at":"2023-08-08T23:39:47-04:00","updated_at":"2023-10-20T02:01:28-04:00","summary_html":"We analyze the ingredients in Agency Skincare's custom formulations based on medical studies to give our take on whether they're likely to have an anti-aging effect or if they're a waste of money. We feature unsponsored before-and-afters.","template_suffix":"","handle":"agency-skincare-review","tags":"_related:anti-aging"}

Agency Skincare Review: Personalized Anti-Aging?

Agency Skincare Review: Personalized Anti-Aging?


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Agency Skincare is a customized skincare brand led by dermatologist recommendations. The brand describes their offerings as “elevated essentials for your skin’s daily needs,” and suggests they have an anti-aging effect.

But does Agency Skincare use research-backed ingredients for anti-aging, or are these just marketing claims? Does the brand use any questionable additive ingredients? Is personalized skincare actually better than off-the-shelf cosmetic products? And how do real users rate and describe the effects of Agency Skincare?

In this article, we’ll answer all of these questions and more as we analyze the ingredients in Agency Skincare based on medical studies to give our take on whether the brand is likely to be effective, or if it’s a waste of money.

We’ll share our thoughts on personalized skincare as a whole and whether it’s a gimmick, and feature unsponsored customer reviews of Agency Skincare.

Ingredient Analysis

We input test answers into the Agency Skincare website health questionnaire indicating our goal was to fight wrinkles.

The active ingredients prescribed are shown below:

Agency Skincare active ingredients

Azelaic acid is typically used for acne, but may also have an anti-aging effect. A 2010 medical review states that “Topical bleaching agents such as hydroquinone, kojic acid and azelaic acid can reduce signs of aging.”

Tretinoin is a derivative of vitamin A that appears highly effective against wrinkles.

A medical review published in the International Journal of Women’s Dermatology found that topical tretinoin was effective against wrinkles in all clinical studies analyzed, and concluded that the treatment “could significantly improve wrinkling.”

Niacinamide is clinically shown to reduce the visible appearance of wrinkles, as we documented in our review of Ambi Fade Cream.

Dexpanethnol promotes cell growth according to a 2021 clinical trial, which suggests it may also be effective against aging.

Tranexamic acid was shown to prevent photoaging in a 2020 animal study, which is a weaker standard of evidence than human studies.

We consider all of the active ingredients in Agency Skincare’s anti-aging formulation to have significant research backing.

Agency Skincare inactive ingredients

Polyacrylamide is a stabilizer described as a “demonstrated neurotoxin in humans” in a 2005 medical review. This review does not prove that this ingredient is absorbed through the skin, but we feel this information is worth highlighting.

BHT is a synthetic preservative that breaks down into BHTOOH, which was described as a tumor promoter in a clinical trial published in the Carcinogenesis journal.

Phenoxyethanol is another synthetic preservative that’s clinically shown to be toxic to human cells. 

Overall, we consider Agency Skincare highly likely to have an anti-aging effect given its prescription-strength active ingredients. We don’t currently recommend this product due to the inactive ingredients highlighted above.

But how do real users rate and describe the effects of Agency Skincare? We’ll feature some unsponsored customer reviews in the next section.

Real People Try Agency Skincare

A TikTok creator named Orah Lasko shared her experience using an Agency Skincare product including before-and-after images:

@orahlasko The Tretinoin glow up is real @Agency Skincare #tretinoin #skincare #skincareroutine ♬ Love Yourself - Jasmine Thompson

A TikTok creator named Mary Margaret has an unsponsored video where she explains why she considers Agency to be a more convenient option than standard prescription skincare:

@mary_hayes Unsponsored honest review of agency’s retinol prescription service-i was gifted this but under no obligation to post this is my opinion after one month! #skincareroutine #tretinoin #tretinoinjourney #agencyskincare ♬ original sound - Mary Margaret

Is Personalized Skincare a Gimmick?

Personalized skincare is becoming more and more popular, and while we all have individual genetics and environmental constraints, we haven’t come across any convincing clinical evidence suggesting that this modality of treatment is better than standard off-the-shelf products or personalized skincare recommendations from a regular dermatologist.

There’s also the issue of data security. 

Agency’s website asks a variety of health questions including pregnancy status, gender and more. As we discussed in our Reverse Health reviews article on another personalized health brand, sharing this information with an online-first healthcare provider may increase the risk of data breaches compared to an in-person provider.

It is worth noting that personalized skincare may lead to better aging results at least in regard to sunscreen recommendations, according to a medical review published in the Clinical, Cosmetic and Investigational Dermatology journal.

Overall, we think that personalized skincare may have benefits, but isn’t worth significantly increased cost based on the current stage of research and our understanding of individual cosmetic factors.

Agency vs. Other Personalized Skincare Brands

A popular beauty vlogger named Abbey Yung compared four personalized skincare brands, including Agency Skincare, in a video with over 100,000 views:

Our Clean Skincare Picks

There are skincare products that contain ingredients shown in clinical trials to be effective for reducing wrinkles and improving skin quality generally.

Annie Mak Vitamin C Serum is our top skin cream pick because of its effective and clean formulation. It contains hyaluronic acid which was described as a "skin-rejuvenating biomedicine" in a medical review due to its ability to reduce wrinkles and signs of facial aging.

Interested consumers can check out Annie Mak Vitamin C Serum at this link to the product page on the official brand's website.

Hydraglow is our top moisturizer pick. It features bakuchiol as an active ingredient which was described in a 2014 clinical trial as "clinically proven to have anti-aging effects."

Interested consumers can check out HydraGlow at this link to the product page on the official brand's website.

The only oral supplement we recommend for skin quality improvement is Bulletproof Collagen Powder.

Oral collagen supplementation was shown in a medical review published in the Journal of Drugs in Dermatology to improve visible signs of skin aging as well as improve skin elasticity and skin hydration.

Interested consumers can check out Bulletproof Collagen Powder at this link to the product page on the brand's official website.

None of the products recommended in this section contain additive ingredients that we consider questionable from a health perspective.

Pros and Cons of Agency Skincare

Here are the pros and cons of Agency Skincare in our opinion:

Pros:

  • More convenient than a visit to a clinic
  • Prescription-strength
  • Likely to have anti-aging effect
  • All active ingredients have research backing
  • Very favorable online customer reviews
  • Personalized skincare may be optimally effective

Cons:

  • Contains synthetic preservatives
  • Contains polyacrylamide
  • Custom, proprietary formulations don’t appear clinically tested
Stay up-to-date on our research reviews

Conclusion

Agency Skincare is one of the more impressive personalized skincare brands we’ve reviewed to date on Illuminate Health.

This brand has an anti-aging focus, and our analysis of the active ingredients used in their anti-aging product(s) suggests they will be effective. All five of the active ingredients in our custom formulation had research backing for anti-aging effects.

We don’t currently recommend Agency Skincare due to the inclusion of three inactive ingredients that may be questionable from a health perspective.

Online customer reviews suggest that Agency is more convenient than an in-person dermatologist visit, and we would tend to agree. This company offers prescription-strength treatments from the comfort of the home.

Online customer reviews of this brand were more favorable than other personalized skincare brands we’ve reviewed.

We have our questions about the efficacy of personalized skincare based on online questionnaires over standard dermatological treatment, but at least one medical review suggests that personalized skincare may be useful for optimizing anti-aging efforts.