{"id":604618654002,"title":"Osteo Bi-Flex Review: Best Joint Health Supplement?","created_at":"2023-01-16T23:36:52-05:00","body_html":"\u003cscript type=\"application\/ld+json\"\u003e\/\/ \u003c![CDATA[\n{\n \"@context\": \"https:\/\/schema.org\",\n \"@type\": \"Article\",\n \"headline\": \"Osteo Bi-Flex Review: Best Joint Health Supplement?\",\n \"keywords\": \"osteo bi flex, osteo bi flex review, osteo bi flex reviews, osteo bi-flex, osteo bi flex triple strength, osteo bi flex ingredients, osteo bi flex side effects, osteo bi flex warning, osteo bi-flex warning, osteo bi flex joint health, triple strength osteo bi flex, osteo bi-flex ingredients, does osteo bi flex work, ingredients in osteo bi flex\",\n \"description\": \"Our research team reviews the ingredients in Osteo Bi-Flex to give our take on whether the supplement is likely to be effective for pain relief and joint support. We highlight a questionable additive ingredient and feature unsponsored reviews from real users of the supplement.\",\n \"url\": \"https:\/\/illuminatelabs.org\/blogs\/health\/osteo-bi-flex-review\",\n\"author\": {\n \"@type\": \"Person\",\n \"name\": \"Calloway Cook\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/calloway-cook\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/calloway-cook\/\",\n \"jobTitle\": \"President\",\n \"knowsAbout\": \"entrepreneurship, dietary supplements, herbal supplements, eCommerce, medical research\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": \"S.I. Newhouse School of Public Communications at Syracuse University\"\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"editor\": {\n \"@type\": \"Person\",\n \"name\": \"Taylor Graber\",\n \"honorificSuffix\": \"M.D.\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/taylor-graber\",\n \"sameAs\": [\n \"https:\/\/www.linkedin.com\/in\/taylor-j-graber-md-81351642\/\",\n \"https:\/\/www.asapivs.com\/\"\n ],\n \"jobTitle\": \"Content Partner\",\n \"knowsAbout\": \"medicine, health, anesthesiology, iv therapy, science, drugs, pharmaceutical, medical research, scientific research, medical journals, entrepreneurship, healthcare, orthopedic surgery, biomedical engineering\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"University of California San Diego\",\n \"Arizona University\",\n \"University of Arizona College of Medicine\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"image\": {\n\"@type\": \"ImageObject\",\n\"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Osteo_Bi-Flex_Thumbnail.png?v=1673930954\",\n\"width\": \"4465\",\n\"height\": \"4465\"\n},\n\"citation\": [\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11904551\/\", \n\"https:\/\/illuminatelabs.org\/blogs\/health\/golden-revive-plus-review\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28790224\/\",\n\"https:\/\/www.efsa.europa.eu\/en\/news\/titanium-dioxide-e171-no-longer-considered-safe-when-used-food-additive\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18756654\/\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6035477\/\",\n\"https:\/\/illuminatelabs.org\/blogs\/health\/midol-ingredients\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29559013\/\",\n\"https:\/\/topclassactions.com\/lawsuit-settlements\/lawsuit-news\/glucosamine-supplement-lawsuit-allegations-against-osteo-bi-flex-include-false-advertising\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29722610\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32638445\/\",\n\"https:\/\/illuminatelabs.org\/products\/ceylon-cinnamon-extract\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18416885\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30368550\/\"\n],\n\"mentions\": [{\n \"@type\": \"Brand\",\n \"name\": \"Osteo Bi-Flex Triple Strength\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"glucosamine\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"chondroitin\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"MSM\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"titanium dioxide\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"iHerb\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Rite Aid\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Walmart\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Amazon\"\n }\n],\n\"datePublished\": \"2023-01-16\",\n\"copyrightHolder\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n},\n\"publisher\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\",\n \"url\": \"https:\/\/illuminatelabs.org\/\",\n \"description\": \"Illuminate Labs is the most transparent supplement company in the U.S., and is a leading publisher of research-based health information.\",\n \"knowsAbout\": \"supplements, science, nutrition, exercise, health, medication, pharmaceutical, wellness, diet, weight loss, medical research\",\n \"publishingPrinciples\": \"https:\/\/illuminatelabs.org\/pages\/editorial-guidelines\",\n \"memberOf\": [\n {\n \"@type\": \"Organization\",\n \"name\": \"U.S. Chamber of Commerce\",\n \"url\": \"https:\/\/www.uschamber.com\/\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Certified B Corp\",\n \"url\": \"https:\/\/www.bcorporation.net\/en-us\/\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Natural Products Association\",\n \"url\": \"https:\/\/www.npanational.org\/\"\n }\n ], \n \"logo\": {\n \"@type\": \"ImageObject\",\n \"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Illuminate_Labs_Favicon_48x48_7595c3cc-e27b-47b8-a4fe-edcc7ed9b29a.png?v=1666502785\", \n \"width\": 48,\n \"height\": 48\n},\n \"foundingDate\": \"2019-01-30\",\n \"sameAs\": [\n \"https:\/\/www.instagram.com\/illuminatelabs\",\n \"https:\/\/twitter.com\/illuminatelabs\",\n \"https:\/\/www.linkedin.com\/company\/illuminate-labs-supplements\",\n \"https:\/\/www.youtube.com\/channel\/UCpgSJAsIPb-fZ25djtTxBEA\"\n ]\n }\n}\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Osteo_Bi-Flex_Review_Article_Header_Image_Optimized.png?v=1673930549\" alt=\"\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cspan class=\"dc\"\u003eO\u003c\/span\u003esteo Bi-Flex is a dietary supplement that promotes joint health. Some consumers use it to relieve pain. The brand claims that users can “start feeling the difference in your joint comfort in just 7 days.”\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eBut does Osteo Bi-Flex contain research-backed ingredients for pain relief and joint support? Does it contain any questionable additive ingredients? How do real users rate it and describe its effects? And can the supplement cause side effects?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn this article we’ll answer all of these questions and more as we review the ingredients in Osteo Bi-Flex based on clinical research to give our take on whether the supplement is likely to be effective or if it’s a waste of money.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe’ll also share our thoughts on whether Osteo Bi-Flex is likely to cause side effects, and feature real, unsponsored user reviews of the supplement.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eIngredient Analysis\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Osteo_Bi-Flex_Triple_Strength_Ingredients_Optimized.png?v=1673930567\" alt=\"Osteo Bi-Flex Triple Strength ingredients\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe ingredients for Osteo Bi-Flex Triple Strength are shown above.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eGlucosamine\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is an effective ingredient for relieving joint pain. A \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11904551\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e compared glucosamine therapy to ibuprofen use for joint pain, and the researchers found the two treatments equally effective. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe exact same dose (1.5 grams) was used in the above-linked review as is included in Osteo Bi-Flex.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eJoint Shield\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is a trademarked ingredient which is an extract of \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eBoswellia serrata\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e, a plant native to India and northern Africa.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAs we documented in our review of \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/golden-revive-plus-review\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eGolden Revive Plus\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e, \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eBoswellia\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e extract is clinically shown to relieve pain in arthritis patients at the same dose as included in Osteo Bi-Flex.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eChondroitin\/MSM Complex\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is the final active ingredient, and this blend appears to be more effective than either ingredient in isolation. A 2017 \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28790224\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e compared the pain relief effects of glucosamine and chondroitin sulfate to the effects of glucosamine and chondroitin sulfate and MSM.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOnly the latter blend reduced pain to a statistically significant degree, and this is the exact same blend as included in Osteo Bi-Flex.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWhile Osteo Bi-Flex is an effectively formulated supplement, it does contain one questionable inactive ingredient.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eTitanium dioxide\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is a colorant that \u003c\/span\u003e\u003ca href=\"https:\/\/www.efsa.europa.eu\/en\/news\/titanium-dioxide-e171-no-longer-considered-safe-when-used-food-additive\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eis banned\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e in the E.U. for use as a food additive over concerns of genotoxicity, which refers to the potential for a compound to cause DNA damage.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOverall, we consider Osteo Bi-Flex to likely be effective for relieving pain and providing joint support. This is a very well-formulated supplement, and is one of the few dietary supplements we’ve reviewed on Illuminate Health with all of its active ingredients appearing to be effectively dosed.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe don’t recommend the supplement due to the inclusion of titanium dioxide, but from an efficacy standpoint, it’s definitely better than the majority of joint support supplements we’ve reviewed.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eReal, Unsponsored Osteo Bi-Flex User Reviews\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA TikTok user named Julie Johnson had favorable things to say about Osteo Bi-Flex’s effects on her joint pain:\u003c\/span\u003e\u003c\/p\u003e\n\u003cblockquote class=\"tiktok-embed\" cite=\"https:\/\/www.tiktok.com\/@justjuliej\/video\/7155828976450325806\" data-video-id=\"7155828976450325806\" style=\"max-width: 325px; min-width: 325px;\"\u003e\n\u003csection\u003e\u003ca target=\"_blank\" title=\"@justjuliej\" href=\"https:\/\/www.tiktok.com\/@justjuliej?refer=embed\" rel=\"noopener noreferrer\"\u003e@justjuliej\u003c\/a\u003e \u003ca title=\"osteobiflex\" target=\"_blank\" href=\"https:\/\/www.tiktok.com\/tag\/osteobiflex?refer=embed\" rel=\"noopener noreferrer\"\u003e#osteobiflex\u003c\/a\u003e \u003ca title=\"supplement\" target=\"_blank\" href=\"https:\/\/www.tiktok.com\/tag\/supplement?refer=embed\" rel=\"noopener noreferrer\"\u003e#supplement\u003c\/a\u003e \u003ca title=\"kneepain\" target=\"_blank\" href=\"https:\/\/www.tiktok.com\/tag\/kneepain?refer=embed\" rel=\"noopener noreferrer\"\u003e#kneepain\u003c\/a\u003e \u003ca title=\"aging\" target=\"_blank\" href=\"https:\/\/www.tiktok.com\/tag\/aging?refer=embed\" rel=\"noopener noreferrer\"\u003e#aging\u003c\/a\u003e \u003ca title=\"midlifecrisis\" target=\"_blank\" href=\"https:\/\/www.tiktok.com\/tag\/midlifecrisis?refer=embed\" rel=\"noopener noreferrer\"\u003e#midlifecrisis\u003c\/a\u003e \u003ca title=\"midlifewomen\" target=\"_blank\" href=\"https:\/\/www.tiktok.com\/tag\/midlifewomen?refer=embed\" rel=\"noopener noreferrer\"\u003e#midlifewomen\u003c\/a\u003e \u003ca target=\"_blank\" title=\"♬ original sound - Julie Johnson\" href=\"https:\/\/www.tiktok.com\/music\/original-sound-7155828970934520619?refer=embed\" rel=\"noopener noreferrer\"\u003e♬ original sound - Julie Johnson\u003c\/a\u003e\u003c\/section\u003e\n\u003c\/blockquote\u003e\n\u003cscript async=\"\" src=\"https:\/\/www.tiktok.com\/embed.js\"\u003e\u003c\/script\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA TikTok user named Cassandra Souza claims to have experienced side effects from Osteo Bi-Flex:\u003c\/span\u003e\u003c\/p\u003e\n\u003cblockquote class=\"tiktok-embed\" cite=\"https:\/\/www.tiktok.com\/@noturnunstoned\/video\/7071634131238554926\" data-video-id=\"7071634131238554926\" style=\"max-width: 325px; min-width: 325px;\"\u003e\n\u003csection\u003e\u003ca target=\"_blank\" title=\"@noturnunstoned\" href=\"https:\/\/www.tiktok.com\/@noturnunstoned?refer=embed\" rel=\"noopener noreferrer\"\u003e@noturnunstoned\u003c\/a\u003e \u003ca title=\"psa\" target=\"_blank\" href=\"https:\/\/www.tiktok.com\/tag\/psa?refer=embed\" rel=\"noopener noreferrer\"\u003e#psa\u003c\/a\u003e \u003ca title=\"sideeffects\" target=\"_blank\" href=\"https:\/\/www.tiktok.com\/tag\/sideeffects?refer=embed\" rel=\"noopener noreferrer\"\u003e#sideeffects\u003c\/a\u003e \u003ca title=\"heartpalpitations\" target=\"_blank\" href=\"https:\/\/www.tiktok.com\/tag\/heartpalpitations?refer=embed\" rel=\"noopener noreferrer\"\u003e#heartpalpitations\u003c\/a\u003e \u003ca title=\"osteobiflex\" target=\"_blank\" href=\"https:\/\/www.tiktok.com\/tag\/osteobiflex?refer=embed\" rel=\"noopener noreferrer\"\u003e#osteobiflex\u003c\/a\u003e \u003ca title=\"tornmenisucus\" target=\"_blank\" href=\"https:\/\/www.tiktok.com\/tag\/tornmenisucus?refer=embed\" rel=\"noopener noreferrer\"\u003e#tornmenisucus\u003c\/a\u003e \u003ca title=\"badkneesclub\" target=\"_blank\" href=\"https:\/\/www.tiktok.com\/tag\/badkneesclub?refer=embed\" rel=\"noopener noreferrer\"\u003e#badkneesclub\u003c\/a\u003e \u003ca title=\"outlanderchallenge\" target=\"_blank\" href=\"https:\/\/www.tiktok.com\/tag\/outlanderchallenge?refer=embed\" rel=\"noopener noreferrer\"\u003e#OutlanderChallenge\u003c\/a\u003e \u003ca title=\"fyp\" target=\"_blank\" href=\"https:\/\/www.tiktok.com\/tag\/fyp?refer=embed\" rel=\"noopener noreferrer\"\u003e#fyp\u003c\/a\u003e \u003ca title=\"anxiety\" target=\"_blank\" href=\"https:\/\/www.tiktok.com\/tag\/anxiety?refer=embed\" rel=\"noopener noreferrer\"\u003e#anxiety\u003c\/a\u003e \u003ca title=\"readthefineprint\" target=\"_blank\" href=\"https:\/\/www.tiktok.com\/tag\/readthefineprint?refer=embed\" rel=\"noopener noreferrer\"\u003e#readthefineprint\u003c\/a\u003e \u003ca title=\"wholetmeadult\" target=\"_blank\" href=\"https:\/\/www.tiktok.com\/tag\/wholetmeadult?refer=embed\" rel=\"noopener noreferrer\"\u003e#wholetmeadult\u003c\/a\u003e \u003ca target=\"_blank\" title=\"♬ A 3-minute song that is ideal for the BGM of cooking videos(1031572) - mi-ya\" href=\"https:\/\/www.tiktok.com\/music\/A-3-minute-song-that-is-ideal-for-the-BGM-of-cooking-videos-1031572-6974532143556855809?refer=embed\" rel=\"noopener noreferrer\"\u003e♬ A 3-minute song that is ideal for the BGM of cooking videos(1031572) - mi-ya\u003c\/a\u003e\u003c\/section\u003e\n\u003c\/blockquote\u003e\n\u003cscript async=\"\" src=\"https:\/\/www.tiktok.com\/embed.js\"\u003e\u003c\/script\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eDoes Osteo Bi-Flex Cause Side Effects?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eConsumers are often curious about whether Osteo Bi-Flex is likely to cause side effects, given that the brand’s website does not include any information about side effects at the time of publishing this article.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOsteo Bi-Flex does not appear to have been studied in any clinical trials, so it’s impossible to say for certain whether or not the supplement will cause side effects. However, we can make an educated guess based on its ingredients.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eGlucosamine\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e, which is the highest-dosed active ingredient in Osteo Bi-Flex, was not shown to cause side effects in a \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18756654\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in the \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eAmerican Family Physician\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e journal.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWhen glucosamine was combined with \u003c\/span\u003e\u003cb\u003echondroitin\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e, the risk of gastrointestinal adverse events was 2.7x higher than placebo, according to a 2018 \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6035477\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emeta-study\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eThis data suggests that Osteo Bi-Flex may cause side effects because it contains both of these active ingredients\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e, however it’s impossible to say conclusively since the brand has not funded a clinical trial.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThere are no warnings listed on the Supplement Facts label, so we do not believe this supplement is likely to cause severe side effects.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eWhere to Buy Osteo Bi-Flex for the Best Price\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOsteo Bi-Flex is sold at a variety of online retailers. Here’s a price breakdown for Osteo Bi-Flex Triple Strength, 120-count:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eiHerb: $50.31\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eRite Aid: $44.99\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWalmart: $29.99\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAmazon: \u003c\/span\u003e\u003cb\u003e$23.29\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e (\u003c\/span\u003e\u003ca rel=\"sponsored\" href=\"https:\/\/amzn.to\/3HcOsp7\"\u003e\u003cspan style=\"font-weight: 400;\"\u003elink to official product listing\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIt’s rare to see such a wide price discrepancy for the same product. Osteo Bi-Flex Triple Strength is currently retailing for 54% less on Amazon than on iHerb.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eReal Customer Reviews of Osteo Bi-Flex\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAmazon is a more objective resource for customer reviews than a brand’s website in our opinion.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe most-reviewed Osteo Bi-Flex product on Amazon is the Triple Strength version we analyzed above. It has over 11,000 ratings with an average review rating of 4.6 out of 5 stars.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe top positive review from a verified purchaser is written by a user named “Allie K.” who claims it’s effective for pain relief:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e“I'd been using topical pain creams, but this has been much more effective for knee pain (sharp pains in left knee walking\/hiking uphill).\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e Can't believe the difference after one month b.i.d.”\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe top negative review from a verified purchaser comes from a user named “Lenny B” who claims it caused side effects:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e“Irregular heartbeats as soon as I started using it! No refund allowed, Amazon must be aware of its issues. You will get cheated and your heath will suffer if you try this!”\u003c\/b\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eWhat’s the Best Osteo Bi-Flex Product?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eTriple Strength is only one of many Osteo Bi-Flex products. Here’s our quick takes on some of the brand’s other products:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eRegular Strength\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eDoesn’t contain MSM so may be less effective. Recall the clinical trial from the previous ingredient analysis which found glucosamine and chondroitin to only be effective for pain relief if combined with MSM.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eTriple Strength + Magnesium\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eDoesn’t contain MSM. Also contains three artificial food dyes: Red 40, Blue 2 and Yellow 5.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAs we documented in our review of \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/midol-ingredients\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eMidol ingredients\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e, artificial dyes have no health benefits and have some toxicity concerns, so it seems logical to avoid supplements containing them.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eTriple Strength with Vitamin D\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eLow vitamin D status is associated with increased risk of joint pain and arthritis according to a \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29559013\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emeta-study\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in the \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003ePublic Health Nutrition\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e journal. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThis supplement may be more effective for patients with low vitamin D status than Osteo Bi-Flex Triple Strength. We’d recommend getting bloodwork done at a doctor’s office to check vitamin D status first.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOverall we consider Osteo Bi-Flex Triple Strength to be the most effective formulation, but Osteo Bi-Flex Triple Strength with Vitamin D may be more effective for patients with low levels of vitamin D.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eWhy Was Osteo Bi-Flex Sued?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn 2018, the manufacturer of Osteo Bi-Flex was sued over claims of false advertising, \u003c\/span\u003e\u003ca href=\"https:\/\/topclassactions.com\/lawsuit-settlements\/lawsuit-news\/glucosamine-supplement-lawsuit-allegations-against-osteo-bi-flex-include-false-advertising\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eaccording to\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e the Top Class Actions website.\u003c\/span\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThe plaintiffs alleged that the supplements were “worthless” because the glucosamine did not relieve pain.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIt’s unclear if the lawsuit was ever brought to trial or if it was settled out-of-court.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWhile in some cases it can be a red flag for a supplement company to be sued, we don’t consider this to be much of a red flag given that there is extensive clinical data backing the active ingredients in Osteo Bi-Flex for joint support. This doesn’t mean that the supplement will work for all consumers, but it’s certainly better-formulated than many joint support and pain relief supplements we’ve reviewed.\u003c\/span\u003e\u003c\/p\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cstrong\u003eCan Cinnamon and Collagen Relieve Pain Naturally?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Cinnamon_Image_a35d9772-699a-46ed-ab66-889abf84c647.png?v=1669955584\" alt=\"\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCinnamon\u003c\/b\u003e\u003cspan\u003e is a spice that has been studied for its ability to reduce pain and support joint health, and it can be taken in a more potent, extracted form. A \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29722610\/\"\u003e\u003cspan\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e published in the \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eJournal of the American College of Nutrition\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e found that cinnamon supplementation at a daily dose of 500 miligrams (mg) reduced inflammation and joint swelling in patients with rheumatoid arthritis.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eA 2020 \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32638445\/\"\u003e\u003cspan\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e found that cinnamon supplementation reduced inflammatory markers. \u003c\/span\u003e\u003cb\u003eThe study authors concluded that “Cinnamon could be regarded as a safe supplement to relieve pain.”\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIlluminate Labs manufactures a \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/products\/ceylon-cinnamon-extract\"\u003e\u003cspan\u003eCeylon Cinnamon Extract\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e supplement that’s potent (standardized to minimum 8% flavonoids) and third-party tested to ensure purity and label accuracy (test results published transparently on the product page). It only costs \u003cstrong\u003e$15\u003c\/strong\u003e for a monthly subscription.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eInterested consumers can check out Illuminate Labs Ceylon Cinnamon Extract \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/products\/ceylon-cinnamon-extract\"\u003e\u003cspan\u003eat this link\u003c\/span\u003e\u003c\/a\u003e to the product page on our website.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCollagen\u003c\/b\u003e is the core structural protein in joints. The body produces it naturally, but its production decreases with age.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18416885\/\"\u003eMedical research\u003c\/a\u003e\u003cspan\u003e \u003c\/span\u003ehas shown that collagen is effective for reducing joint pain in athletes at a 10 gram (g) daily dose, and for reducing arthritic pain generally (\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30368550\/\"\u003e\u003cspan\u003emeta-study\u003c\/span\u003e\u003c\/a\u003e, doses ranging between 40 mg and 10 g daily dose).\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eWe recommend \u003c\/span\u003e\u003ca rel=\"sponsored\" href=\"https:\/\/bulletproof.fdf2.net\/c\/3271428\/1278011\/9221\"\u003e\u003cspan\u003eBulletproof Collagen Powder\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e as our top collagen product because it provides an effective collagen dose per serving (20 g) and contains one single ingredient: collagen peptides sourced from grass-fed animals. There are no questionable additives. This supplement only costs \u003cstrong\u003e$39.95\u003c\/strong\u003e for over a month's worth of product.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eInterested consumers can check out Bulletproof Collagen powder \u003c\/span\u003e\u003ca rel=\"sponsored\" href=\"https:\/\/bulletproof.fdf2.net\/c\/3271428\/1278011\/9221\"\u003e\u003cspan\u003eat this link\u003c\/span\u003e\u003c\/a\u003e to the product page on the brand's website.\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eConclusion\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOsteo Bi-Flex is likely to relieve pain and support joint health in our opinion, because all three of the active ingredients in the supplement are effectively dosed and are clinically shown to have positive health effects.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe supplement contains an inactive ingredient which is banned in the E.U. over genotoxicity concerns, otherwise we would consider recommending it.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOnline customer reviews of Osteo Bi-Flex appear to be relatively positive, and we consider the supplement to be of higher quality than the average pain relief and joint support supplement we’ve reviewed.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOsteo Bi-Flex Triple Strength is the best-formulated supplement sold by the brand in our opinion, although the version with vitamin D added may be more effective for patients with low vitamin D levels.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAt the time of publishing this article, Osteo Bi-Flex is significantly cheaper on Amazon than on other retailer websites.\u003c\/span\u003e\u003c\/p\u003e","blog_id":49281925193,"author":"Calloway Cook","user_id":26601750601,"published_at":"2023-01-16T23:55:12-05:00","updated_at":"2023-01-16T23:55:12-05:00","summary_html":"We review the ingredients in Osteo Bi-Flex to give our take on whether the supplement is likely to be effective for pain relief and joint support. We highlight a questionable additive ingredient and feature unsponsored reviews from real users of the supplement.","template_suffix":"","handle":"osteo-bi-flex-review","tags":"_related:arthritis, _related:pain-relief"}

Osteo Bi-Flex Review: Best Joint Health Supplement?

Osteo Bi-Flex Review: Best Joint Health Supplement?


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Osteo Bi-Flex is a dietary supplement that promotes joint health. Some consumers use it to relieve pain. The brand claims that users can “start feeling the difference in your joint comfort in just 7 days.”

But does Osteo Bi-Flex contain research-backed ingredients for pain relief and joint support? Does it contain any questionable additive ingredients? How do real users rate it and describe its effects? And can the supplement cause side effects?

In this article we’ll answer all of these questions and more as we review the ingredients in Osteo Bi-Flex based on clinical research to give our take on whether the supplement is likely to be effective or if it’s a waste of money.

We’ll also share our thoughts on whether Osteo Bi-Flex is likely to cause side effects, and feature real, unsponsored user reviews of the supplement.

Ingredient Analysis

Osteo Bi-Flex Triple Strength ingredients

The ingredients for Osteo Bi-Flex Triple Strength are shown above.

Glucosamine is an effective ingredient for relieving joint pain. A medical review compared glucosamine therapy to ibuprofen use for joint pain, and the researchers found the two treatments equally effective. 

The exact same dose (1.5 grams) was used in the above-linked review as is included in Osteo Bi-Flex.

Joint Shield is a trademarked ingredient which is an extract of Boswellia serrata, a plant native to India and northern Africa.

As we documented in our review of Golden Revive Plus, Boswellia extract is clinically shown to relieve pain in arthritis patients at the same dose as included in Osteo Bi-Flex.

Chondroitin/MSM Complex is the final active ingredient, and this blend appears to be more effective than either ingredient in isolation. A 2017 clinical trial compared the pain relief effects of glucosamine and chondroitin sulfate to the effects of glucosamine and chondroitin sulfate and MSM.

Only the latter blend reduced pain to a statistically significant degree, and this is the exact same blend as included in Osteo Bi-Flex.

While Osteo Bi-Flex is an effectively formulated supplement, it does contain one questionable inactive ingredient.

Titanium dioxide is a colorant that is banned in the E.U. for use as a food additive over concerns of genotoxicity, which refers to the potential for a compound to cause DNA damage.

Overall, we consider Osteo Bi-Flex to likely be effective for relieving pain and providing joint support. This is a very well-formulated supplement, and is one of the few dietary supplements we’ve reviewed on Illuminate Health with all of its active ingredients appearing to be effectively dosed.

We don’t recommend the supplement due to the inclusion of titanium dioxide, but from an efficacy standpoint, it’s definitely better than the majority of joint support supplements we’ve reviewed.

Real, Unsponsored Osteo Bi-Flex User Reviews

A TikTok user named Julie Johnson had favorable things to say about Osteo Bi-Flex’s effects on her joint pain:

@justjuliej #osteobiflex #supplement #kneepain #aging #midlifecrisis #midlifewomen ♬ original sound - Julie Johnson

A TikTok user named Cassandra Souza claims to have experienced side effects from Osteo Bi-Flex:

@noturnunstoned #psa #sideeffects #heartpalpitations #osteobiflex #tornmenisucus #badkneesclub #OutlanderChallenge #fyp #anxiety #readthefineprint #wholetmeadult ♬ A 3-minute song that is ideal for the BGM of cooking videos(1031572) - mi-ya

Does Osteo Bi-Flex Cause Side Effects?

Consumers are often curious about whether Osteo Bi-Flex is likely to cause side effects, given that the brand’s website does not include any information about side effects at the time of publishing this article.

Osteo Bi-Flex does not appear to have been studied in any clinical trials, so it’s impossible to say for certain whether or not the supplement will cause side effects. However, we can make an educated guess based on its ingredients.

Glucosamine, which is the highest-dosed active ingredient in Osteo Bi-Flex, was not shown to cause side effects in a medical review published in the American Family Physician journal.

When glucosamine was combined with chondroitin, the risk of gastrointestinal adverse events was 2.7x higher than placebo, according to a 2018 meta-study.

This data suggests that Osteo Bi-Flex may cause side effects because it contains both of these active ingredients, however it’s impossible to say conclusively since the brand has not funded a clinical trial.

There are no warnings listed on the Supplement Facts label, so we do not believe this supplement is likely to cause severe side effects.

Where to Buy Osteo Bi-Flex for the Best Price

Osteo Bi-Flex is sold at a variety of online retailers. Here’s a price breakdown for Osteo Bi-Flex Triple Strength, 120-count:

iHerb: $50.31

Rite Aid: $44.99

Walmart: $29.99

Amazon: $23.29 (link to official product listing)

It’s rare to see such a wide price discrepancy for the same product. Osteo Bi-Flex Triple Strength is currently retailing for 54% less on Amazon than on iHerb.

Real Customer Reviews of Osteo Bi-Flex

Amazon is a more objective resource for customer reviews than a brand’s website in our opinion.

The most-reviewed Osteo Bi-Flex product on Amazon is the Triple Strength version we analyzed above. It has over 11,000 ratings with an average review rating of 4.6 out of 5 stars.

The top positive review from a verified purchaser is written by a user named “Allie K.” who claims it’s effective for pain relief:

“I'd been using topical pain creams, but this has been much more effective for knee pain (sharp pains in left knee walking/hiking uphill). Can't believe the difference after one month b.i.d.”

The top negative review from a verified purchaser comes from a user named “Lenny B” who claims it caused side effects:

“Irregular heartbeats as soon as I started using it! No refund allowed, Amazon must be aware of its issues. You will get cheated and your heath will suffer if you try this!”

What’s the Best Osteo Bi-Flex Product?

Triple Strength is only one of many Osteo Bi-Flex products. Here’s our quick takes on some of the brand’s other products:

Regular Strength

Doesn’t contain MSM so may be less effective. Recall the clinical trial from the previous ingredient analysis which found glucosamine and chondroitin to only be effective for pain relief if combined with MSM.

Triple Strength + Magnesium

Doesn’t contain MSM. Also contains three artificial food dyes: Red 40, Blue 2 and Yellow 5.

As we documented in our review of Midol ingredients, artificial dyes have no health benefits and have some toxicity concerns, so it seems logical to avoid supplements containing them.

Triple Strength with Vitamin D

Low vitamin D status is associated with increased risk of joint pain and arthritis according to a meta-study published in the Public Health Nutrition journal. 

This supplement may be more effective for patients with low vitamin D status than Osteo Bi-Flex Triple Strength. We’d recommend getting bloodwork done at a doctor’s office to check vitamin D status first.

Overall we consider Osteo Bi-Flex Triple Strength to be the most effective formulation, but Osteo Bi-Flex Triple Strength with Vitamin D may be more effective for patients with low levels of vitamin D.

Why Was Osteo Bi-Flex Sued?

In 2018, the manufacturer of Osteo Bi-Flex was sued over claims of false advertising, according to the Top Class Actions website.

The plaintiffs alleged that the supplements were “worthless” because the glucosamine did not relieve pain.

It’s unclear if the lawsuit was ever brought to trial or if it was settled out-of-court.

While in some cases it can be a red flag for a supplement company to be sued, we don’t consider this to be much of a red flag given that there is extensive clinical data backing the active ingredients in Osteo Bi-Flex for joint support. This doesn’t mean that the supplement will work for all consumers, but it’s certainly better-formulated than many joint support and pain relief supplements we’ve reviewed.

Can Cinnamon and Collagen Relieve Pain Naturally?

Cinnamon is a spice that has been studied for its ability to reduce pain and support joint health, and it can be taken in a more potent, extracted form. A clinical trial published in the Journal of the American College of Nutrition found that cinnamon supplementation at a daily dose of 500 miligrams (mg) reduced inflammation and joint swelling in patients with rheumatoid arthritis.

A 2020 clinical trial found that cinnamon supplementation reduced inflammatory markers. The study authors concluded that “Cinnamon could be regarded as a safe supplement to relieve pain.”

Illuminate Labs manufactures a Ceylon Cinnamon Extract supplement that’s potent (standardized to minimum 8% flavonoids) and third-party tested to ensure purity and label accuracy (test results published transparently on the product page). It only costs $15 for a monthly subscription.

Interested consumers can check out Illuminate Labs Ceylon Cinnamon Extract at this link to the product page on our website.

Collagen is the core structural protein in joints. The body produces it naturally, but its production decreases with age. Medical research has shown that collagen is effective for reducing joint pain in athletes at a 10 gram (g) daily dose, and for reducing arthritic pain generally (meta-study, doses ranging between 40 mg and 10 g daily dose).

We recommend Bulletproof Collagen Powder as our top collagen product because it provides an effective collagen dose per serving (20 g) and contains one single ingredient: collagen peptides sourced from grass-fed animals. There are no questionable additives. This supplement only costs $39.95 for over a month's worth of product.

Interested consumers can check out Bulletproof Collagen powder at this link to the product page on the brand's website.

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Conclusion

Osteo Bi-Flex is likely to relieve pain and support joint health in our opinion, because all three of the active ingredients in the supplement are effectively dosed and are clinically shown to have positive health effects.

The supplement contains an inactive ingredient which is banned in the E.U. over genotoxicity concerns, otherwise we would consider recommending it.

Online customer reviews of Osteo Bi-Flex appear to be relatively positive, and we consider the supplement to be of higher quality than the average pain relief and joint support supplement we’ve reviewed.

Osteo Bi-Flex Triple Strength is the best-formulated supplement sold by the brand in our opinion, although the version with vitamin D added may be more effective for patients with low vitamin D levels.

At the time of publishing this article, Osteo Bi-Flex is significantly cheaper on Amazon than on other retailer websites.




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