Inno Cleanse is a gut health, detox and weight loss supplement manufactured by Inno Supps, the same company that makes Nitro Wood. The company claims that this supplement can reduce bloating, improve energy levels and help with weight loss.
But does Inno Cleanse contain research-backed ingredients for gut health and weight loss? Does it contain any dangerous ingredients? Will it cause side effects? And is Inno Cleanse better or worse than popular detox brands like Biocol Labs?
In this article we’ll answer all of these questions and more, as we analyze the ingredients in Inno Cleanse to give our take on whether or not the supplement is likely to be effective, and whether or not it's healthy.
We’ll also share our concerns about some of the ingredient doses, discuss the risk of side effects, and compare Inno Cleanse to other popular detox supplements to pick our winners (and losers).
Key takeaways:
- We're unconvinced that "cleanse" supps are effective
- Contains an active ingredient that can cause liver damage
- We do not currently recommend Inno Cleanse
Ingredient Analysis
The ingredients in Inno Cleanse are shown below:
The “Waist-Trimming Complex” is the highest-dosed ingredient blend in this supplement, and contains several active ingredients that we consider to be questionable from a health perspective.
Cascara sagrada bark powder is a laxative that may cause liver injury depending on the dose.
A medical review published in the LiverTox journal on this ingredient concludes the following:
"The time to onset of liver injury [from cascara use] has varied from a few days to 2 months of use."
Senna is another laxative ingredient that may be harsh on the liver.
As we referenced in our ZuPOO reviews article, this ingredient has been clinically shown to cause liver injury at high doses.
Use of laxatives may cause short-term weight loss due to fluid loss, but they do not cause sustainable long-term weight loss, because laxative use does not cause fat loss.
There are no ingredients in the Waist-Trimming Complex that we consider safe and effective for weight loss.
Fennel seed powder is the first ingredient in the “Advanced Digestion Complex,” and this ingredient is also described as a laxative in a 2022 medical review.
Using three separate laxatives may be harsh on the gut, rather than healing.
Slippery elm bark powder is a potentially effective ingredient for gut health, as it was found in a 2010 clinical trial to reduce irritable bowel syndrome (IBS) symptoms in combination with other natural ingredients.
The “Pro Gut Health Matrix” contains ingredients at such low doses that we consider them unlikely to be effective.
Capiscum annum fruit powder is more commonly known as cayenne pepper.
This is the same ingredient you can find in the spice aisle at a grocery store. The average ingredient dose in this blend is 20 milligrams (mg).
One single tablespoon of cayenne pepper has a dose of 5,300 mg according to the USDA, which means that one single tablespoon of cayenne contains a dose 2,600x higher than the amount in Inno Cleanse.
We do not currently recommend Inno Cleanse, because we are unable to identify any ingredients we consider effective for either weight loss or gut health at the stated dose.
Does Inno Cleanse Cause Side Effects?
Inno Cleanse does not appear to have been studied in any clinical trials, so it’s challenging to say for certain whether or not it causes side effects.
However, we can make an educated guess based on its ingredients.
Because Inno Cleanse contains three separate laxative ingredients, it may be a higher-risk supplement in regard to digestive side effects than the average gut health supplement.
As an example, Cascara sagrada can cause cramps in the intestines and even electrolyte imbalances due to its diuretic and laxative properties, according to a medical review published in the Chemical Research in Toxicology journal.
A medical review on the use of senna in children to treat constipation found that 13% of patients experienced abdominal cramping, vomiting or diarrhea.
We consider Inno Cleanse moderately likely to cause side effects such as digestive upset due to the multiple laxatives it contains.
Do “Cleanses” Even Make Logical Sense?
The entire concept of “cleansing” with the use of a dietary supplement is questionable in our opinion, as we haven’t come across any clinical evidence that this type of treatment is useful or necessary.
As we discussed in our Detoxify Mega Clean reviews article, the purpose of the liver and kidneys is to detoxify the body, and we haven’t come across any medical studies suggesting that additional, supplemental detoxification is necessary.
Individuals may feel as though they are experiencing a “detox” when they defecate more due to the use of laxatives, but taking laxatives simply accelerates the process of digestion and defecation. It’s not “cleansing” the body or digestive tract in any way.
Inno Cleanse vs. Popular Detox Supps
Here's how Inno Cleanse compares to other popular detox supplements in terms of formulation quality, in our opinion:
Stinger Detox
Contains many ingredients we consider unhealthy, including 50 grams (g) of added sugar, which is clinically shown to contribute to obesity.
However, there are no ingredients in Stinger Detox we consider to be acutely dangerous, so we give the brand the advantage from a safety perspective.
Winner: Stinger Detox
Biocol Labs
Biocol Labs is a newer-generation detox supplement brand.
It contains two inactive ingredients we consider to be unhealthy, as we documented in the above-linked review, but nothing we consider acutely dangerous.
Winner: Biocol Labs
High Voltage Detox
Contains some research-backed active ingredients for liver support, and no acutely dangerous ingredients.
High Voltage Detox has the advantage from both a potential efficacy standpoint and a safety standpoint.
Winner: High Voltage Detox
Our Clean Gut Health Picks
MBG Organic Fiber Potency+ is our top gut health supplement.
MBG Organic Fiber Potency+ contains 100% soluble fiber, which was described as "one of the most important nutrients for the gut microbiota" in a clinical review published in the Molecules journal.
Manukora MGO 850+ is our top whole food gut health pick.
A 2024 clinical trial reported that manuka honey ingestion "correlates with beneficial modulation of gut microbiota composition."
Both of the products recommended in this section are free of ingredients that we consider to be unhealthy.
Inno Cleanse Pros and Cons
Pros:
- Safe inactive ingredients
Cons:
- Questionable active ingredients
- Contains three separate laxatives
- "Cleanse" supplements may be unnecessary
- May cause digestive upset
- Doesn't appear to be clinically tested
- More safety concerns than competitors
