URO is a vaginal health supplement sold by a women’s health brand called O POSITIVE. The brand claims that the capsule supplement “supports healthy vaginal odor and pH.”
But can oral supplements really support vaginal health? Does URO contain ingredients shown in studies to improve vaginal health? Does it contain any unhealthy ingredients? And is URO better or worse than popular vaginal health supplements like Uqora?
In this article we’ll answer all of these questions and more, as we analyze the ingredients in URO to give our take on whether or not it's likely to be effective for vaginal health, and whether or not it contains any unhealthy additives.
We'll also compare URO to other popular vaginal health supplements to pick our winners.
Key takeaways:
- We consider URO likely to reduce negative vaginal odor based on its ingredients
- Highly positive customer reviews
- We currently recommend URO
Ingredient Analysis
The ingredients in URO are shown below:
While many consumers refer to the product as “URO vitamins,” it’s actually a probiotic supplement rather than a vitamin supplement.
V-Positive Probiotic Blend is the core active ingredient, and it’s a blend of four probiotic species with a total dose of 5 billion colony-forming units (CFU).
Probiotics may be effective for treating and preventing bacterial vaginosis (BV), which can cause negative changes to vaginal odor. A medical review published in the Clinical Microbiology and Infection journal reported the following:
“intra-vaginal administration of Lactobacillus acidophilus for 6-12 days, or oral administration of L. acidophilus or Lactobacillus rhamnosus GR-1 and Lactobacillus fermentum RC-14 for 2 months, resulted in the cure of BV”.
URO contains all three of the probiotic species listed above, so it may be effective against BV.
Lactobacillus reuteri is the fourth probiotic species in URO, and was shown in a 2020 clinical trial to reduce the levels of a pathogenic bacteria in the vagina during pregnancy, and “improve the pregnancy outcome.”
We agree with O POSITIVE’s decision to formulate this supplement with Lactobacillus probiotics, because as described in a 2022 medical review, Lactobacillus is the most abundant probiotic in the vagina, and helps to maintain the low pH of the vagina which prevents growth of harmful bacteria.
Clearly there are a number of potentially effective active ingredients in URO, and the inactive ingredients are safe and non-toxic as well.
Natural color is an additive ingredient that’s derived from edible sources like fruits and vegetables that gives the supplement its pink color. This is a healthier alternative to artificial colors, which may be harmful to human health as discussed in our best probiotic for women article.
We consider URO likely to support optimal vaginal health including pH and odor based on its active ingredients.
OB/GYN on Probiotic Vaginal Supplements
A gynecologist was featured in a video on the popular “The Doctors” YouTube channel, discussing the potential benefits and downsides of probiotic supplements for the vagina.
The video has over 80,000 views and is under two minutes long:
URO vs. Popular Vaginal Health Supps
Here's how URO compares to other popular vaginal health supplements in terms of potential effectiveness and healthiness, in our opinion
Uqora
The manufacturer of this supplement makes questionable health claims that we consider unscientific, as we discussed in our Uqora review article.
Also a worse formulation from a potential efficacy perspective.
Winner: URO
Lactomedi
This injectable probiotic supplement for the vagina doesn't appear to be clinically tested, which we consider to be a (minor) concern for injectable health products.
Winner: URO
AZO Yeast Plus
This supplement not only contains an active ingredient which is clinically shown to cause yeast infections, but is a homeopathic remedy.
Homeopathy is clinically shown to be ineffective.
Winner: URO
Our Clean Vaginal Health Picks
MBG Omega-3 Potency+ is our top vaginal moisture pick.
Oral supplementation with omega-3 fatty acids has been clinically shown to relieve vaginal dryness in some individuals.
MBG Vitamin D3 Potency+ is our top vaginal health pick.
A 2015 meta-analysis reported that treatment of vitamin D deficiency "is an effective method in the treatment of asymptomatic bacterial vaginosis."
Both of the products recommended in this section are free of ingredients that we consider to be unhealthy.
URO Pros and Cons
Pros:
- Contains research-backed probiotics for vaginal health
- No unhealthy additive ingredients
- Affordable for a specialty supplement
- Mostly positive online customer reviews
- Unlikely to cause side effects
Cons:
- Doesn’t appear clinically tested
- Brand fails to describe natural colorant compound
- May not be necessary for those with a healthy vagina
