Get $25 Off On Subscription Orders!

{"id":556554321993,"title":"Ozempic Review: Can Diabetes Medication Cause Weight Loss?","created_at":"2022-06-09T15:05:39-04:00","body_html":"\u003cscript type=\"application\/ld+json\"\u003e\/\/ \u003c![CDATA[\n{\n \"@context\": \"https:\/\/schema.org\",\n \"@type\": \"Article\",\n \"headline\": \"Ozempic Review: Can Diabetes Medication Cause Weight Loss?\",\n \"keywords\": \"ozempic, ozempic reviews, ozempic review, ozempic side effects, ozempic for weight loss, ozempic weight loss, ozempic foods to avoid, ozempic weight loss before and after pictures, ozempic dosing, side effects of ozempic, wegovy vs ozempic, ozempic drug class, how does ozempic work, is ozempic insulin, ozempic dosage, ozempic for weight loss reviews, ozempic vs trulicity, what is ozempic used for, ozempic generic\",\n \"description\": \"Our MD and research team reviews the medical research on Ozempic to determine how it works and whether it’s likely to be effective for diabetes and weight loss. We overview some side effects of the drug, dosage information, and compare it to other popular diabetes and weight loss medications.\",\n \"url\": \"https:\/\/illuminatelabs.org\/blogs\/health\/ozempic-review\",\n\"author\": {\n \"@type\": \"Person\",\n \"name\": \"Taylor Graber MD\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/taylor-graber\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/taylor-j-graber-md-81351642\/\",\n \"jobTitle\": \"Content Partner\",\n \"knowsAbout\": \"medicine, health, anesthesiology, iv therapy, science, drugs, pharmaceutical, medical research, scientific research, medical journals, entrepreneurship, healthcare, orthopedic surgery, biomedical engineering\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"University of California San Diego\",\n \"Arizona University\",\n \"University of Arizona College of Medicine\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"creator\": {\n \"@type\": \"Person\",\n \"name\": \"Taylor Graber MD\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/taylor-graber\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/taylor-j-graber-md-81351642\/\",\n \"jobTitle\": \"Content Partner\",\n \"knowsAbout\": \"medicine, health, anesthesiology, iv therapy, science, drugs, pharmaceutical, medical research, scientific research, medical journals, entrepreneurship, healthcare, orthopedic surgery, biomedical engineering\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"University of California San Diego\",\n \"Arizona University\",\n \"University of Arizona College of Medicine\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"contributor\": {\n \"@type\": \"Person\",\n \"name\": \"Calloway Cook\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/calloway-cook\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/calloway-cook\/\",\n \"jobTitle\": \"President\",\n \"knowsAbout\": \"entrepreneurship, dietary supplements, herbal supplements, eCommerce, medical research\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": \"S.I. Newhouse School of Public Communications at Syracuse University\"\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"editor\": {\n \"@type\": \"Person\",\n \"name\": \"DJ Mazzoni\",\n \"honorificSuffix\": [\n \"M.S.\",\n \"R.D.\",\n \"C.D.N.\",\n \"C.S.C.S.\"\n ],\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/dj-mazzoni\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/dj-mazzoni-rd-cdn-cscs-00a33038\/\",\n \"jobTitle\": \"Medical Reviewer\",\n \"knowsAbout\": \"exercise, drugs, pharmaceutical, health, workout, strength and conditioning, nutrition, dietetics, medicine, medical research, scientific research, scientific method, healthcare, patient care, wellness\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"State University of New York College Oswego\",\n \"D’Youville College\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"image\": {\n\"@type\": \"ImageObject\",\n\"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Ozempic_Thumbnail_e03e215e-84da-47ab-937a-23f48d7cadea.png?v=1654802581\",\n\"width\": \"2581\",\n\"height\": \"2581\"\n},\n\"citation\": [\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29756388\/\", \n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5836914\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31637820\/\",\n\"https:\/\/www.ozempic.com\/\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8717485\/\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5573908\/\",\n\"https:\/\/illuminatelabs.org\/blogs\/health\/wegovy-review\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8294388\/\",\n\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2020\/209637s003lbl.pdf\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32815454\/\",\n\"https:\/\/www.ozempic.com\/lifestyle-tips\/healthy-eating.html\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29397376\/\",\n\"https:\/\/www.ozempic.com\/savings-and-resources\/save-on-ozempic.html\",\n\"https:\/\/www.drugs.com\/comments\/semaglutide\/ozempic.html\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6415809\/\"\n],\n\"mentions\": [{\n \"@type\": \"Thing\",\n \"name\": \"type 2 diabetes\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"semaglutide\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"blood sugar\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"insulin\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"FDA\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"GLP-1RA\"\n }\n],\n\"datePublished\": \"2022-06-09\",\n\"copyrightHolder\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n},\n\"publisher\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\",\n \"url\": \"https:\/\/illuminatelabs.org\/\",\n \"description\": \"Illuminate Labs is the most transparent supplement company in the U.S., and is a leading publisher of research-based health information.\",\n \"knowsAbout\": \"supplements, science, nutrition, exercise, health, medication, pharmaceutical, wellness, diet, weight loss, medical research\",\n \"publishingPrinciples\": \"https:\/\/illuminatelabs.org\/pages\/editorial-guidelines\",\n \"logo\": {\n \"@type\": \"ImageObject\",\n \"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Illuminate_Labs_Logo.png?v=1641249064\", \n \"width\": 150,\n \"height\": 150\n},\n \"foundingDate\": \"2019-01-30\",\n \"Address\": {\n \"@type\": \"PostalAddress\",\n \"streetAddress\": \"50 Union Street, Unit 9\",\n \"addressLocality\": \"Northampton\",\n \"addressRegion\": \"Massachusetts\",\n \"postalCode\": \"01060\",\n \"addressCountry\": \"US\"\n},\n \"sameAs\": [\n \"https:\/\/www.instagram.com\/illuminatelabs\",\n \"https:\/\/twitter.com\/illuminatelabs\",\n \"https:\/\/www.linkedin.com\/company\/illuminate-labs-supplements\",\n \"https:\/\/www.youtube.com\/channel\/UCpgSJAsIPb-fZ25djtTxBEA\"\n ]\n }\n}\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003cp\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Ozempic_Review_Article_Header_Image_Optimized_3f1f4211-7ded-4af6-a8b0-bf1dc5e4ceb5.png?v=1654802908\" alt=\"\"\u003e\u003c\/span\u003e\u003c\/i\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eDisclaimer: None of the information in this article constitutes medical advice, and is just the opinion of the writer(s) and published for informational purposes only. We recommend that patients follow their doctor’s guidance in regard to prescription medication.\u003c\/span\u003e\u003c\/i\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cspan class=\"dc\"\u003eO\u003c\/span\u003eOzempic is a prescription injectable medication for adults with type 2 diabetes. It’s one of the most popular diabetes medications prescribed in the U.S. Ozempic is the brand name version of the drug, and the generic version is called semaglutide. We will use these names interchangeably throughout this article as they refer to the same active compound.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn this article we’ll review the medical research on Ozempic to determine how it works and whether it’s likely to be effective for diabetes and weight loss. We’ll also overview some side effects of the drug, dosage information, and explain foods you may wish to avoid while taking Ozempic.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eDoes Ozempic Work for Diabetes?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAs noted in the intro, Ozempic is primarily a diabetes drug. This is the only condition that’s approved to treat by the Food and Drug Administration (FDA) in the U.S. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29756388\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emeta-study\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in the Diabetes, Obesity and Metabolism journal analyzed data from 7 individual trials on Ozempic to treat type 2 diabetes. The researchers noted that Ozempic reduced HbA1c (a marker of blood sugar) by 1.01% and 1.38% at the lower doses of the drug. This was found to be a statistically significant reduction.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA separate \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5836914\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in 2018 found that Ozempic reduced blood sugar spike after a meal in obese patients, and improved insulin sensitivity.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA more recent \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31637820\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e that was even more comprehensive analyzed the efficacy of Ozempic for treating type 2 diabetes. The study authors analyzed data from 9,980 patients and concluded that the drug “can safely and effectively reduce blood glucose.”\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe can conclude from the available data that Ozempic is effective for treating diabetes, which is unsurprising given that it was approved by the FDA for this purpose, which requires significant clinical backing.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eDoes Ozempic Cause Weight Loss?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOne of the most common questions that patients have about Ozempic is whether it can influence weight loss. Ozempic’s \u003c\/span\u003e\u003ca href=\"https:\/\/www.ozempic.com\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ewebsite\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e has conflicting information on this topic which could be confusing to a patient. The brand states that “Ozempic may help you lose some weight,” but then in the next line states “Ozempic is not for weight loss.”\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe reason the brand has to be cautious about their wording here is that Ozempic is not approved by the FDA for weight loss, so the drug manufacturer cannot claim the product is effective for weight loss even if there is some medical research suggesting it may be.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8717485\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in 2022 examined whether Ozempic was effective for inducing weight loss. The researchers found some surprising results.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOne study found that Ozempic at 0.5 milligrams (mg) caused an average body weight reduction of 3.73 kilograms (kg) over 30 weeks, which equates to 8.22 pounds (lbs). 37% of patients at this dose lost over 5% of their total body weight over the 30 week trial.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe same study found that Ozempic at 1 mg caused an average body weight reduction of 4.53 kg over 30 weeks, which equates to 9.99 lb. 45% of patients at this dose lost over 5% of their body weight over the 30 week trial.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5573908\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in the Diabetes, Obesity and Metabolism journal elucidated why Ozempic may be effective for weight loss. The drug reduced hunger and food cravings, and caused a reduced preference for high-fat foods. This may be due to the effect that normalizing insulin levels has on reducing food cravings.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAnother interesting thing to note on the topic of Ozempic and weight loss is that Ozempic is the same active drug (semaglutide) that is approved by the FDA for weight loss at a higher dose. \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/wegovy-review\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eWegovy\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e is a semaglutide prescription drug, but its dose is 2.4 mg while the highest available dose of Ozempic is 2 mg.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAll of the available research suggests that Ozempic may be effective for weight loss in overweight and obese patients, however we don’t recommend that patients take the drug for that purpose alone as it’s not approved by the FDA for weight loss.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIf weight loss is the goal, we recommend that patients speak with their doctor instead about Wegovy which is approved for weight loss and uses the same active ingredient but at a higher dose.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eOzempic Side Effects\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe side effects of Ozempic are well-documented. In fact, there is an entire \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8294388\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e just on the side effects of Ozempic. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe most common side effect of Ozempic is nausea, occurring in upwards of 20% of patients. Vomiting occurred in a range of 4% to 11.5% of patients, and diarrhea occurred in 4.5% to 11.3% of patients. Older patients with other medical conditions were noted to experience these side effects more than average.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe more concerning potential side effect of Ozempic is that of thyroid tumors. The medication carries a “black box warning” on its \u003c\/span\u003e\u003ca href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2020\/209637s003lbl.pdf\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eFDA label\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e, which is the highest level of patient warning which indicates a side effect that may cause serious safety risks.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOzempic’s black box warning notes that in rodents the drug causes thyroid C-cell tumors. For this reason it’s contraindicated for patients with a family history of some thyroid conditions. We recommend that patients speak with their doctor about these risks prior to taking the drug.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eHow Does Ozempic Work?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOzempic is a glucagon-like peptide-1 receptor agonist (GLP-1RA). This class of compounds is effective for diabetes because it can help the body regulate levels of glucose.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAccording to \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32815454\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical research\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e, GLP-1RA drugs may inhibit the release of a hormone called glucagon which is commonly elevated in type 2 diabetics. This hormone signals to the body to increase blood sugar levels, so by inhibiting its effect blood sugar levels may drop.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eFor weight loss, Ozempic may be effective because of its effects on hunger and satiation as we reviewed in the previous section. The drug also delays gastric emptying which causes patients to feel full longer.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eDo I Need to Avoid Certain Foods on Ozempic?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThere’s a common patient misconception that there are specific foods which cannot be eaten on Ozempic. That is not true and there is no information in the FDA label on this drug about specific foods that need to be avoided. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThat being said, because Ozempic is a type 2 diabetes medication it seems logical to avoid processed foods with a high glycemic index that are likely to cause blood sugar spikes and potentially worsen diabetes. Avoiding foods like chips, cakes, cookies and candy may make Ozempic more effective.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOzempic’s website even has a \u003c\/span\u003e\u003ca href=\"https:\/\/www.ozempic.com\/lifestyle-tips\/healthy-eating.html\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ehealthy eating section\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e where they recommend different plant-based meals which are rich in nutrition. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe recommendation to eat high-fiber, unprocessed foods makes even more sense for patients who are hoping for a secondary benefit of weight loss while taking the drug. Eating high-calorie, processed foods would be counterintuitive to weight loss.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eOzempic Dose\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOzempic is available at three different once-weekly doses, according to their website: 0.5 mg, 1 mg and 2 mg. Higher doses are generally associated with increased efficacy and increased side effects.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn the medical reviews we highlighted in the weight loss section of this article, higher Ozempic doses were also associated with increased weight loss.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eDoctors often start patients on a lower dose of the medication to establish tolerability, and then increase dose as needed. We recommend that patients speak with their doctor about what an appropriate Ozempic dose is based on their individual medical situation.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eOzempic Weight Loss Before and After\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAlthough Ozempic is not prescribed for weight loss, many patients are often curious about seeing before-and-after images of another patient who was prescribed Ozempic and experienced weight loss as a secondary effect.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA YouTube creator named “The Hangry Woman” has one of the most popular before-and-after videos highlighting her weight loss on Ozempic after 6 months. She claims to have lost 29 pounds:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ciframe width=\"560\" height=\"315\" src=\"https:\/\/www.youtube.com\/embed\/w-3cgQE6kG0\" title=\"YouTube video player\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen=\"\"\u003e\u003c\/iframe\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eIs Ozempic Insulin?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eBecause insulin is the most commonly-prescribed medication for type 2 diabetes, there is often patient confusion about whether Ozempic is just a new type of insulin.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOzempic is not insulin but it can help regulate insulin secretion. The way Ozempic works is by regulating the hormones glucagon and insulin to better manage blood sugar.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWhen patients become type 2 diabetic, their hormone levels often become dysregulated, and Ozempic helps the body normalize these hormone levels which has downstream effects on blood sugar. This is a different mechanism of action than directly injecting with insulin which also reduces blood sugar.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eOzempic Vs. Trulicity\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eTrulicity is another type 2 diabetes medication which is the brand name for a generic compound called dulaglutide. Both drugs are in the GLP-1RA class of compounds.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29397376\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e directly compared the effectiveness of Ozempic and Trulicity for treating type 2 diabetes. The researchers found that at both low and high doses, Ozempic was superior to Trulicity in improving blood sugar levels and also for weight reduction. A greater number of patients on Ozempic hit their blood sugar targets than those on Trulicity.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eBased on the available research, we would recommend that patients speak with their doctor about Ozempic rather than Trulicity if they suffer from type 2 diabetes.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eWhat Is The Ozempic Copay Card?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOzempic offers a copay card accessible through their website that can help patients save money on the medication. The \u003c\/span\u003e\u003ca href=\"https:\/\/www.ozempic.com\/savings-and-resources\/save-on-ozempic.html\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eOzempic savings page\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e on the manufacturer website allows patients to text the brand to receive their card.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe copay card advertises online that patients can pay as little as $25 for a 1-month, 2-month or 3-month supply for up to 24 months.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe resource page also has a co-pay lookup tool that allows patients to find their co-pay cost in advance, which can help for financial planning.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eOzempic User Reviews\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOne of the most useful tools for analyzing user reviews of pharmaceutical medications is Drugs.com. Their \u003c\/span\u003e\u003ca href=\"https:\/\/www.drugs.com\/comments\/semaglutide\/ozempic.html\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eOzempic user reviews\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e resource features reviews from over 500 people at the time of writing.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eFor type 2 diabetes, users have rated Ozempic 5.7\/10. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe top-rated positive review of Ozempic comes from a reviewer named “Zell” who claims the drug helped them lose weight:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e“What a miracle! 9 months later and I’m down 40 lbs”\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe top-rated negative review is written by a user named “Stingie” who reported negative side effects after taking the drug:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e“I did one injection and have been ill since. Have had acid reflux, burping, vomiting, constipation, headache and dizziness.”\u003c\/b\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eShould I Take Ozempic Generic?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAs referenced throughout this article, the generic form of Ozempic is called semaglutide. These two names refer to the exact same active compound; Ozempic is just the branded version.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMedical research \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6415809\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eshows\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e that brand-name and generic drugs have similar efficacy, which logically follows since they have the same active ingredient.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe typically recommend that patients speak with their doctor about the generic version of a drug rather than the brand-name version, since the latter costs more and may provide no additional health benefit.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn Ozempic’s case, it’s unclear if generic semaglutide injections are available yet, but we recommend that patients speak with their doctor about this.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eConclusion\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOzempic is an injectable medication which can help patients manage type 2 diabetes by reducing their blood sugar and normalizing their insulin function. The drug may also be effective for weight loss as a secondary benefit, but it is not yet approved for weight loss by the FDA.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe recommend that patients interested in weight loss speak instead with their doctor about Wegovy, because this medication uses a higher dose of the same active ingredient as Ozempic, and is approved by the FDA for weight management in overweight patients.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOzempic’s most common side effects are relatively minor, such as nausea and diarrhea, but there may be a small risk of severe side effects such as tumors, at least based on animal studies.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThere is no need to avoid specific foods while using Ozempic, and the notion that this is necessary is a common patient misconception. We do recommend that patients on Ozempic try to eat a healthy diet with unprocessed whole foods, as this is likely to benefit both type 2 diabetes and weight loss.\u003c\/span\u003e\u003c\/p\u003e","blog_id":49281925193,"author":"Calloway Cook","user_id":26601750601,"published_at":"2022-06-09T15:27:56-04:00","updated_at":"2022-06-09T15:28:34-04:00","summary_html":"We review the medical research on type 2 diabetes medication Ozempic to determine how it works and whether it’s likely to be effective for diabetes and weight loss. We overview some side effects of the drug, dosage information, and compare it to other popular diabetes and weight loss medications.","template_suffix":"","handle":"ozempic-review","tags":"_related:diabetes, _related:weight-loss"}

Ozempic Review: Can Diabetes Medication Cause Weight Loss?

Ozempic Review: Can Diabetes Medication Cause Weight Loss?


| |
Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.
| |
Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.


Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.

Disclaimer: None of the information in this article constitutes medical advice, and is just the opinion of the writer(s) and published for informational purposes only. We recommend that patients follow their doctor’s guidance in regard to prescription medication.

OOzempic is a prescription injectable medication for adults with type 2 diabetes. It’s one of the most popular diabetes medications prescribed in the U.S. Ozempic is the brand name version of the drug, and the generic version is called semaglutide. We will use these names interchangeably throughout this article as they refer to the same active compound.

In this article we’ll review the medical research on Ozempic to determine how it works and whether it’s likely to be effective for diabetes and weight loss. We’ll also overview some side effects of the drug, dosage information, and explain foods you may wish to avoid while taking Ozempic.

Does Ozempic Work for Diabetes?

As noted in the intro, Ozempic is primarily a diabetes drug. This is the only condition that’s approved to treat by the Food and Drug Administration (FDA) in the U.S. 

A meta-study published in the Diabetes, Obesity and Metabolism journal analyzed data from 7 individual trials on Ozempic to treat type 2 diabetes. The researchers noted that Ozempic reduced HbA1c (a marker of blood sugar) by 1.01% and 1.38% at the lower doses of the drug. This was found to be a statistically significant reduction.

A separate medical trial published in 2018 found that Ozempic reduced blood sugar spike after a meal in obese patients, and improved insulin sensitivity.

A more recent medical review that was even more comprehensive analyzed the efficacy of Ozempic for treating type 2 diabetes. The study authors analyzed data from 9,980 patients and concluded that the drug “can safely and effectively reduce blood glucose.”

We can conclude from the available data that Ozempic is effective for treating diabetes, which is unsurprising given that it was approved by the FDA for this purpose, which requires significant clinical backing.

Does Ozempic Cause Weight Loss?

One of the most common questions that patients have about Ozempic is whether it can influence weight loss. Ozempic’s website has conflicting information on this topic which could be confusing to a patient. The brand states that “Ozempic may help you lose some weight,” but then in the next line states “Ozempic is not for weight loss.”

The reason the brand has to be cautious about their wording here is that Ozempic is not approved by the FDA for weight loss, so the drug manufacturer cannot claim the product is effective for weight loss even if there is some medical research suggesting it may be.

A medical review published in 2022 examined whether Ozempic was effective for inducing weight loss. The researchers found some surprising results.

One study found that Ozempic at 0.5 milligrams (mg) caused an average body weight reduction of 3.73 kilograms (kg) over 30 weeks, which equates to 8.22 pounds (lbs). 37% of patients at this dose lost over 5% of their total body weight over the 30 week trial.

The same study found that Ozempic at 1 mg caused an average body weight reduction of 4.53 kg over 30 weeks, which equates to 9.99 lb. 45% of patients at this dose lost over 5% of their body weight over the 30 week trial.

A medical review published in the Diabetes, Obesity and Metabolism journal elucidated why Ozempic may be effective for weight loss. The drug reduced hunger and food cravings, and caused a reduced preference for high-fat foods. This may be due to the effect that normalizing insulin levels has on reducing food cravings.

Another interesting thing to note on the topic of Ozempic and weight loss is that Ozempic is the same active drug (semaglutide) that is approved by the FDA for weight loss at a higher dose. Wegovy is a semaglutide prescription drug, but its dose is 2.4 mg while the highest available dose of Ozempic is 2 mg.

All of the available research suggests that Ozempic may be effective for weight loss in overweight and obese patients, however we don’t recommend that patients take the drug for that purpose alone as it’s not approved by the FDA for weight loss.

If weight loss is the goal, we recommend that patients speak with their doctor instead about Wegovy which is approved for weight loss and uses the same active ingredient but at a higher dose.

Ozempic Side Effects

The side effects of Ozempic are well-documented. In fact, there is an entire medical review just on the side effects of Ozempic. 

The most common side effect of Ozempic is nausea, occurring in upwards of 20% of patients. Vomiting occurred in a range of 4% to 11.5% of patients, and diarrhea occurred in 4.5% to 11.3% of patients. Older patients with other medical conditions were noted to experience these side effects more than average.

The more concerning potential side effect of Ozempic is that of thyroid tumors. The medication carries a “black box warning” on its FDA label, which is the highest level of patient warning which indicates a side effect that may cause serious safety risks.

Ozempic’s black box warning notes that in rodents the drug causes thyroid C-cell tumors. For this reason it’s contraindicated for patients with a family history of some thyroid conditions. We recommend that patients speak with their doctor about these risks prior to taking the drug.

How Does Ozempic Work?

Ozempic is a glucagon-like peptide-1 receptor agonist (GLP-1RA). This class of compounds is effective for diabetes because it can help the body regulate levels of glucose.

According to medical research, GLP-1RA drugs may inhibit the release of a hormone called glucagon which is commonly elevated in type 2 diabetics. This hormone signals to the body to increase blood sugar levels, so by inhibiting its effect blood sugar levels may drop.

For weight loss, Ozempic may be effective because of its effects on hunger and satiation as we reviewed in the previous section. The drug also delays gastric emptying which causes patients to feel full longer.

Do I Need to Avoid Certain Foods on Ozempic?

There’s a common patient misconception that there are specific foods which cannot be eaten on Ozempic. That is not true and there is no information in the FDA label on this drug about specific foods that need to be avoided. 

That being said, because Ozempic is a type 2 diabetes medication it seems logical to avoid processed foods with a high glycemic index that are likely to cause blood sugar spikes and potentially worsen diabetes. Avoiding foods like chips, cakes, cookies and candy may make Ozempic more effective.

Ozempic’s website even has a healthy eating section where they recommend different plant-based meals which are rich in nutrition. 

The recommendation to eat high-fiber, unprocessed foods makes even more sense for patients who are hoping for a secondary benefit of weight loss while taking the drug. Eating high-calorie, processed foods would be counterintuitive to weight loss.

Ozempic Dose

Ozempic is available at three different once-weekly doses, according to their website: 0.5 mg, 1 mg and 2 mg. Higher doses are generally associated with increased efficacy and increased side effects.

In the medical reviews we highlighted in the weight loss section of this article, higher Ozempic doses were also associated with increased weight loss.

Doctors often start patients on a lower dose of the medication to establish tolerability, and then increase dose as needed. We recommend that patients speak with their doctor about what an appropriate Ozempic dose is based on their individual medical situation.

Ozempic Weight Loss Before and After

Although Ozempic is not prescribed for weight loss, many patients are often curious about seeing before-and-after images of another patient who was prescribed Ozempic and experienced weight loss as a secondary effect.

A YouTube creator named “The Hangry Woman” has one of the most popular before-and-after videos highlighting her weight loss on Ozempic after 6 months. She claims to have lost 29 pounds:

Is Ozempic Insulin?

Because insulin is the most commonly-prescribed medication for type 2 diabetes, there is often patient confusion about whether Ozempic is just a new type of insulin.

Ozempic is not insulin but it can help regulate insulin secretion. The way Ozempic works is by regulating the hormones glucagon and insulin to better manage blood sugar.

When patients become type 2 diabetic, their hormone levels often become dysregulated, and Ozempic helps the body normalize these hormone levels which has downstream effects on blood sugar. This is a different mechanism of action than directly injecting with insulin which also reduces blood sugar.

Ozempic Vs. Trulicity

Trulicity is another type 2 diabetes medication which is the brand name for a generic compound called dulaglutide. Both drugs are in the GLP-1RA class of compounds.

A medical trial directly compared the effectiveness of Ozempic and Trulicity for treating type 2 diabetes. The researchers found that at both low and high doses, Ozempic was superior to Trulicity in improving blood sugar levels and also for weight reduction. A greater number of patients on Ozempic hit their blood sugar targets than those on Trulicity.

Based on the available research, we would recommend that patients speak with their doctor about Ozempic rather than Trulicity if they suffer from type 2 diabetes.

What Is The Ozempic Copay Card?

Ozempic offers a copay card accessible through their website that can help patients save money on the medication. The Ozempic savings page on the manufacturer website allows patients to text the brand to receive their card.

The copay card advertises online that patients can pay as little as $25 for a 1-month, 2-month or 3-month supply for up to 24 months.

The resource page also has a co-pay lookup tool that allows patients to find their co-pay cost in advance, which can help for financial planning.

Ozempic User Reviews

One of the most useful tools for analyzing user reviews of pharmaceutical medications is Drugs.com. Their Ozempic user reviews resource features reviews from over 500 people at the time of writing.

For type 2 diabetes, users have rated Ozempic 5.7/10. 

The top-rated positive review of Ozempic comes from a reviewer named “Zell” who claims the drug helped them lose weight:

“What a miracle! 9 months later and I’m down 40 lbs”

The top-rated negative review is written by a user named “Stingie” who reported negative side effects after taking the drug:

“I did one injection and have been ill since. Have had acid reflux, burping, vomiting, constipation, headache and dizziness.”

Should I Take Ozempic Generic?

As referenced throughout this article, the generic form of Ozempic is called semaglutide. These two names refer to the exact same active compound; Ozempic is just the branded version.

Medical research shows that brand-name and generic drugs have similar efficacy, which logically follows since they have the same active ingredient.

We typically recommend that patients speak with their doctor about the generic version of a drug rather than the brand-name version, since the latter costs more and may provide no additional health benefit.

In Ozempic’s case, it’s unclear if generic semaglutide injections are available yet, but we recommend that patients speak with their doctor about this.

Get our most popular articles straight to your inbox
Stay up-to-date on our research reviews

Conclusion

Ozempic is an injectable medication which can help patients manage type 2 diabetes by reducing their blood sugar and normalizing their insulin function. The drug may also be effective for weight loss as a secondary benefit, but it is not yet approved for weight loss by the FDA.

We recommend that patients interested in weight loss speak instead with their doctor about Wegovy, because this medication uses a higher dose of the same active ingredient as Ozempic, and is approved by the FDA for weight management in overweight patients.

Ozempic’s most common side effects are relatively minor, such as nausea and diarrhea, but there may be a small risk of severe side effects such as tumors, at least based on animal studies.

There is no need to avoid specific foods while using Ozempic, and the notion that this is necessary is a common patient misconception. We do recommend that patients on Ozempic try to eat a healthy diet with unprocessed whole foods, as this is likely to benefit both type 2 diabetes and weight loss.





Liquid error: Could not find asset snippets/search-bar.liquid