Inno Cleanse Review: Are Detox Supps Dangerous?

Inno Cleanse Review: Are Detox Supps Dangerous?

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Inno Cleanse is a gut health, detox and weight loss supplement manufactured by Inno Supps, the same company that makes Nitro Wood. The company claims that this supplement can reduce bloating, improve energy levels and help with weight loss.

But does Inno Cleanse contain research-backed ingredients for gut health and weight loss or are these just marketing claims? Does it contain any dangerous ingredients? Will the supplement cause side effects? And how do real users rate and describe its effects?

In this article we’ll answer all of these questions and more as we review the ingredients in Inno Cleanse based on medical studies and give our take on whether the supplement is likely to be effective or if it’s a waste of money.

We’ll share our concerns about some of the ingredient doses and the missing inactive ingredients, and highlight real, unsponsored user reviews of this supplement.

Ingredient Analysis

Inno Cleanse ingredients

The “Waist-Trimming Complex” is the highest-dosed ingredient blend in this supplement, and contains several questionable active ingredients. 

Cascara sagrada bark powder is a laxative ingredient that may cause liver injury depending on the dose. A medical review published in the LiverTox journal on this ingredient concludes the following: "The time to onset of liver injury [from cascara use] has varied from a few days to 2 months of use."

Senna is another laxative ingredient that may be harsh on the liver. As we referenced in our ZuPOO reviews article, this ingredient has been clinically shown to cause liver injury at high doses.

We want to note that use of laxatives may cause short-term weight loss due to fluid loss, but they do not cause sustainable long-term weight loss because laxative use does not cause fat loss.

There are no ingredients in the Waist-Trimming Complex that we consider safe and effective for weight loss.

Fennel seed powder is the first ingredient in the “Advanced Digestion Complex” and this ingredient is also described as a laxative in a 2022 medical review. Using three separate natural laxatives may be harsh on the gut rather than healing.

Slippery elm bark powder is a potentially effective ingredient for gut health, as it was found in a 2010 clinical trial to reduce irritable bowel syndrome (IBS) symptoms in combination with other natural ingredients.

The “Pro Gut Health Matrix” contains ingredients in such low doses that we consider them unlikely to be effective.

Capiscum annum fruit powder is more commonly known as cayenne pepper. This is the same ingredient you can find in the spice aisle at a grocery store. The average ingredient dose in this blend is 20 mg. One single tablespoon of cayenne pepper has a dose of 5,300 mg according to the USDA, which means that one single tablespoon of cayenne contains a dose 2,600x higher than the amount in Inno Cleanse.

Overall we consider this to be a poorly formulated supplement as we are unable to identify any ingredients we consider effective for either weight loss or gut health at the stated dose. We do not believe that Inno Cleanse is likely to be effective for the health claims made by the brand.

Missing Inactive Ingredients

As documented in the Supplement Facts label shown in the previous section, there is no inactive ingredient list published by Inno Supps. 

This is a consumer safety issue, because consumers cannot make an informed decision about what ingredients they’re putting into their body without a full ingredient list.

Every dietary supplement in capsule form contains both active ingredients (like the ones reviewed in the previous section) and inactive ingredients (like the capsule material, filler material, etc). Consumers may have an allergy to an inactive ingredient or there may be inactive ingredients in a formulation like artificial flavors that health-conscious consumers choose to avoid.

We urge Inno Supps to publish the inactive ingredients list on their Supplement Facts label, and we recommend that consumers avoid supplements without both an active ingredient and inactive ingredient list published (in the case of powder supplements there is sometimes no inactive ingredient list).

Real Customers Rate Inno Cleanse

Inno Cleanse is sold on Amazon, which is a more objective resource for customer reviews than a brand’s website in our opinion. The supplement has been reviewed over 5,800 times with an average review rating of 4 out of 5 stars.

The top positive review from a verified purchaser comes from a user named “Katie tran” who claims who claims that it was effective for their partner:

“Let me tell you when I say this stuff works, it works. My man took it for the first time today and he’s been in the bathroom more than he’s been with me. Talk about a cleanse detox! Like he moves slightly and you can tell he’s been releasing gas all day.”

The top negative review from a verified purchaser is written by a user named “Ross Fazekas” who claims that the product was ineffective and that the brand failed to honor their money-back guarantee:

“Well, after taking 2 pills per day for 3 days I had no purging or cleansing action happening at all.

Product didn't work for me so I'll return it for my money back. Amazon stated that this product was "not eligible for return" with no satisfactory explanation why. They advertise it as "100% money back guarantee". Not cool to give no refund.

So I contacted Inno Supps directly for a refund. They refused a refund. Said I had to get it from Amazon. I told them their selling partner would not refund so Inno Supps should. Especially since they are advertising on Amazon as "100% money back guarantee". No dice they said. False advertising.”

A Youtube creator named “Serious Keto” reviewed Inno Cleanse and took the supplement for a full 30 days to determine if it caused weight loss or any other effects:

Does Inno Cleanse Cause Side Effects?

Inno Cleanse does not appear to have been studied in any clinical trials, so it’s impossible to say for certain whether or not it causes side effects. However, we can make an educated guess based on its ingredients. 

Because Inno Cleanse contains three separate laxative ingredients, it may be a higher-risk supplement in regard to digestive side effects than the average gut health supplement.

As an example, Cascara sagrada can cause cramps in the intestines and even electrolyte imbalances due to its diuretic and laxative properties, according to a medical review published in the Chemical Research in Toxicology journal.

A medical review on the use of senna in children to treat constipation found that 13% of patients experienced abdominal cramping, vomiting or diarrhea.

We consider Inno Cleanse moderately likely to cause side effects such as digestive upset due to the multiple laxatives it contains.

Do “Cleanses” Even Make Logical Sense?

The entire concept of “cleansing” with the use of a dietary supplement is questionable in our opinion, as we haven’t come across any clinical evidence that this type of treatment is useful or necessary.

As we discussed in our Detoxify Mega Clean reviews article, the purpose of the liver and kidneys is to detoxify the body, and we haven’t come across any medical studies suggesting that additional, supplemental detoxification is necessary.

Consumers may feel as though they are experiencing a “detox” when they defecate more due to the use of laxatives, but taking laxatives simply accelerates the process of digestion and defecation. It’s not “cleansing” the body or digestive tract in any way.

Dr. Jen Caudle explains whether or not cleanses work for weight loss, and if they make sense generally in a video on her YouTube page with over 10,000 views:

Our Clean Gut Health Picks

MBG Organic Fiber Potency+ is our top fiber pick because it's certified organic, provides 7 g of fiber per serving and costs under $1.85 per serving at the time of updating this article.

MBG Organic Fiber Potency+ contains 100% soluble fiber, which was described as "one of the most important nutrients for the gut microbiota" in a clinical review published in the Molecules journal.

Bulletproof Express 3-in-1 Probiotic is our top value probiotic supplement, because it costs only $1.20 per serving at the time of updating this article.

Probiotics "can improve in the immune, systems in healthy adults" according to a 2019 medical review.

VSL#3 is our top premium probiotic pick, because this probiotic supplement has been studied in 25 clinical trials, and a 2020 meta-study on VSL#3 concluded the following:

"...many studies demonstrated that VSL#3 has a beneficial effect on obesity and diabetes, allergic diseases, nervous systemic diseases, AS, bone diseases, and female reproductive systemic diseases."

All of the products recommended in this section are entirely free of ingredients that we consider to be unhealthy or unsafe.

Stay up-to-date on our research reviews


Inno Cleanse contains a number of laxatives which may cause temporary weight loss due to loss of water weight and fecal matter, however we do not consider this supplement likely to be effective for long-term weight loss or improved gut health.

We are unable to identify any active ingredients in Inno Cleanse that are shown in clinical trials to be effective for the stated health claims, and we do not recommend the supplement overall.

The Supplement Facts label on Inno Supps’ website is missing an inactive ingredient list, and we urge the brand to publish this information. Consumers deserve to know the full list of ingredients they’re putting in their body, and it’s impossible to make a safe and informed purchase decision without this information.

Inno Cleanse may cause side effects like indigestion and nausea due to the three laxative ingredients it contains. Some of these laxative ingredients are associated with risk of liver injury when taken at high doses.