Testoprime Review: Natural T Booster or Dangerous?

Testoprime Review: Natural T Booster or Dangerous?

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Disclaimer: None of the information in this article constitutes medical advice, and is just the opinion of the writer(s). We recommend that patients follow their doctor’s guidance in regard to testosterone support.

Testoprime is a dietary supplement for testosterone support. The brand claims their supplement can can “stop low-T in its tracks,” and that it can "increase mental and physical energy on demand."

But does Testoprime contain research-backed ingredients for supporting optimal testosterone levels, or are these just marketing claims? Does the supplement contain any questionable additive ingredients? How do real users rate and describe the effects of Testoprime? And what retailer sells this supplement for the best price?

In this article we'll answer all of these questions and more as we analyze the ingredients in Testoprime based on medical studies to give our take on whether the supplement is likely to be effective for supporting testosterone (T) levels, or if it's a waste of money.

We'll share some concerns about the product's manufacturer, feature a real customer review, explain why T levels are dropping across the developed world and share our thoughts on the risks of buying this product on Amazon.

Ingredient Analysis

Testoprime vitamin and mineral ingredients

The vitamin and mineral ingredients in Testoprime (vitamin D3, vitamin B6, vitamin B5 and zinc) are shown above.

It may be unsafe to take high doses of vitamins and minerals without a deficiency in those vitamins or minerals. 

A medical review on zinc toxicity published in The American Journal of Clinical Nutrition documents that 100 milligrams (mg) of zinc per day may cause toxicity due to its effects on copper depletion.

Testoprime provides 40 mg in one serving, or 40% of what appears to be the minimum dose to induce deficiency, and consumers may get additional zinc from multivitamins and diet. We would strongly caution patients to speak with their doctor prior to regularly taking such a high zinc dose.

Testoprime botanical ingredients

The botanical and inactive ingredients in Testoprime are shown above. We apologize for the low quality and legibility of these images. This is what the brand publishes.

D-aspartic acid is included at a 2,000 mg dose. A 2017 clinical trial on d-aspartic acid supplementation at a dose 3x higher than that in Testoprime found that this ingredient had no effect on testosterone levels.

A second trial actually found that d-aspartic acid actually decreased testosterone levels. We consider this a likely ineffective ingredient.

Panax ginseng was shown in a clinical trial published in the Nutrients journal to slightly increase T levels in women, but we can't find any research suggesting it has the same effect in men (though it may increase libido).

Ashwagandha root extract is the third-listed ingredient, and as we documented in our ashwagandha reviews article, is one of the few herbs that's clinically shown to increase testosterone levels.

Doses of ashwagandha extract vary significantly in clinical research, but the 55.68 mg dose is lower than the vast majority of studies we've come across.

Fenugreek seed extract was shown in a 2020 meta-study to increase T levels, and one of the clinical trials analyzed used a dose similar to that in Testoprime.

Pomegranate extract is a strange choice for a T-boosting supplement.

A 2020 clinical trial found that pomegranate juice decreased post-workout T levels, and the dose in Testoprime is only equivalent to 360 mg of pomegranate powder. 

To give a sense of how low of a dose that is for a fruit, the USDA reports that one pomegranate has a dose of 282,000 mg. This means that one single pomegranate has over 700 times the dose of the amount of pomegranate in Testoprime.

The good news is that the inactive ingredients in this formulation are safe and non-toxic.

Overall, we consider Testoprime potentially effective for improving T levels given the research backing of some of its active ingredients and the seemingly-effective fenugreek seed extract dose.

We don't currently recommend this supplement due to the vitamin and mineral ingredients and the active ingredients that may actually decrease T levels and counteract any benefit from the more anabolic ingredients.

It's also worth noting that we had to look in the "FAQs" section of the Testoprime website to find this Supplement Facts label. The brand does not publish this ingredient label in the Ingredients section of their site, and we urge them to do so because this information is important for consumers to make an informed purchase decision.

But does the supplement cause side effects? We'll discuss in the next section.

Does Testoprime Cause Side Effects?

Testoprime doesn't appear to have been studied in any clinical trials, so it's challenging to say for certain whether or not it causes side effects. However, we can make an educated guess based on its ingredients.

Green tea extract may cause liver damage according to a 2011 medical review, which is why we recommend extreme caution with supplements containing this ingredient.

The relatively high vitamin and mineral doses may also increase the risk of side effects.

As we documented in our review of Roman Testosterone Support, another wellness brand recently recalled some of their products from the market because the overfortification of vitamins was causing toxicity in some customers.

Overall, we don't believe Testoprime is likely to cause side effects in otherwise healthy adults, but we do believe it has a higher chance to cause side effects than the average supplement due to its ingredients and their respective doses.

Highly Questionable Health Claims on Testoprime Website

There are a number of strange and uncited health claims on the Testoprime website.

The brand suggests that their supplement reduces stress by over 70%:

Testoprime questionable health claim 1

We don't understand how Testoprime can make such a specific health claim if their supplement has not been clinically proven to have that effect. We have no idea where this number comes from, and the asterisk is not to any clinical citation but just to a disclaimer that this statement isn't evaluated by the FDA.

The brand also claims that their supplement can increase muscle strength by over 100%:

Testoprime questionable health claim 2

Again, there is no proof provided for this claim. We consider it to be a major red flag when a supplement company makes specific health claims without providing any proof of those claims.

On the same page, the following graphic is shown:

Testoprime questionable health claim 3

We haven't seen any evidence that Testoprime, or any research published by Testoprime, has been confirmed by any of these organizations, nor does the brand cite any.

Why is Male Testosterone Dropping?

Male testosterone levels dropping across the developed world is a real trend, and appears to be caused primarily by environmental factors.

A medical review published in 2007 documented a decline in serum testosterone levels in American men. The study authors noted that the decline “does not appear to be attributable to observed changes in explanatory factors, including health and lifestyle characteristics such as smoking and obesity.”

A more recent medical review found the same. The testosterone deficiency rate by 2021 had jumped to 20% in adolescent and young adult males in the U.S., and T levels were shown to have steadily decreased over a period of nearly two decades that the researchers tracked data.

As we detailed in our article on the bpa free meaning, plastics are made with chemical compounds like BPA and BPS which are endocrine disrupting and may decrease testosterone levels in men.

These compounds have documented estrogenic effects in the body, and we know from medical research that humans are unintentionally consuming more microplastics than ever because they’re so pervasive in our environment.

A YouTube video from a creator named Silas Willoughby has over 750,000 views and discusses why T levels are so low today, and shares a few natural ways to improve them:

Where to Buy Testoprime

While we don’t recommend Testoprime, we would recommend that consumers intent on purchasing this product do so through the manufacturer’s website and not on Amazon.

Often, when brands don’t sell on Amazon, other companies will sell products under the same name. This is an entirely unethical practice that Amazon should ban because it’s unsafe for consumers.

This appears to be the case with Testoprime. The brand doesn't appear to sell on major online retailers like Amazon or GNC, and so there are other brands selling products on Amazon called “Testoprime” with totally different ingredients. One of the top “Testoprime” products is sold by a brand named “Fyvus” which is designed to have a similar coloration to Testoprime but has different ingredients:

Testoprime Amazon product image

Real User Reviews Testoprime

One of the most popular reviews of Testoprime is from a YouTube creator called “Male Supplement Reviews.” Their review of the supplement is favorable, and they claim that Testoprime is effectively formulated:

    Our Testosterone Support Picks

    Bulletproof Magnesium is our top overall testosterone support pick.

    Magnesium is a mineral that is clinically shown to increase free and total testosterone in athletes and in sedentary individuals.

    Momentous Vitamin D3 is our top value testosterone support pick.

    Vitamin D3 supplementation has been clinically shown to increase total testosterone levels by over 25%.

    Momentous Tongkat Ali is our top herbal testosterone support pick.

    A 2022 meta-study concluded that "A significant improvement in total testosterone levels after [tongkat ali] treatment was mostly reported in both healthy volunteers and hypogonadal men." 

    All of the products recommended in this section are entirely free of additive ingredients that we consider unhealthy.

    Pros and Cons of Testoprime

    Here are the pros and cons of Testoprime in our opinion:


    • Large number of research-backed ingredients
    • Fenugreek seed extract is effectively dosed
    • Inactive ingredients are safe and non-toxic


    • Contains high vitamin and mineral doses
    • Contains green tea extract
    • Doesn't appear clinically tested
    • Brand doesn't clearly publish Supplement Facts label on product page
    • Extremely low pomegranate dose
    • Brand makes questionable and uncited health claims
    Stay up-to-date on our research reviews


    Testoprime does have a large number of research-backed ingredients for supporting T levels, but we can only identify one of those ingredients (fenugreek seed extract) as being effectively dosed based on a review of clinical studies.

    We're concerned by the high vitamin and mineral doses in this supplement, and would caution consumers to clear use of this supplement with their doctor prior to taking it for extended periods of time.

    The inactive ingredients in Testoprime are safe and non-toxic, and we don't believe the supplement is likely to cause side effects in otherwise healthy adults. However, it doesn't appear to have been clinically tested so it's challenging to say for certain.

    There are a number of questionable and uncited health claims on the Testoprime website, including the suggestion that the supplement increases muscle strength by over 100%. We urge the brand to either provide proof of these claims or remove them entirely from their website.

    Testosterone levels are dropping across the developed world, but there are also natural ways to optimize testosterone, some of which were discussed in a YouTube video that we shared in this article.

    While we don't recommend Testoprime overall, consumers intent on purchasing it should do so on the manufacturer's website (which we linked in this article for convenience) rather than Amazon, because the Amazon listings appear to be entirely different products with different ingredients to the official Testoprime.