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{"id":555976949833,"title":"Phentermine Review: Can The Drug Cause Weight Loss?","created_at":"2021-11-21T22:10:40-05:00","body_html":"\u003cscript type=\"application\/ld+json\"\u003e\/\/ \u003c![CDATA[\n{\n \"@context\": \"https:\/\/schema.org\",\n \"@type\": \"Article\",\n \"headline\": \"Phentermine Review: Can The Drug Cause Weight Loss?\",\n \"keywords\": \"phentermine, phentermine side effects, phentermine weight loss, phentermine review, phentermine reviews, phentermine diet pills, what is phentermine, phentermine pills, side effects of phentermine, how does phentermine work, phentermine for weight loss, phentermine weight loss pills, phentermine results, is phentermine safe, appetite suppressant phentermine, contrave vs phentermine, does phentermine work, phentermine appetite suppressant\",\n \"description\": \"Our MD reviews medical studies on phentermine to determine if it’s likely to be safe and effective for weight loss, and we also provide some research-backed natural alternatives which may be as effective with fewer side effects.\",\n \"url\": \"https:\/\/illuminatelabs.org\/blogs\/health\/phentermine-review\",\n\"author\": {\n \"@type\": \"Person\",\n \"name\": \"Taylor Graber MD\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/taylor-graber\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/taylor-j-graber-md-81351642\/\",\n \"jobTitle\": \"Content Partner\",\n \"knowsAbout\": \"medicine, health, anesthesiology, iv therapy, science, drugs, pharmaceutical, medical research, scientific research, medical journals, entrepreneurship, healthcare, orthopedic surgery, biomedical engineering\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"University of California San Diego\",\n \"Arizona University\",\n \"University of Arizona College of Medicine\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"contributor\": {\n \"@type\": \"Person\",\n \"name\": \"Calloway Cook\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/calloway-cook\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/calloway-cook\/\",\n \"jobTitle\": \"President\",\n \"knowsAbout\": \"entrepreneurship, dietary supplements, herbal supplements, eCommerce, medical research\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": \"S.I. Newhouse School of Public Communications at Syracuse University\"\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"editor\": {\n \"@type\": \"Person\",\n \"name\": \"DJ Mazzoni\",\n \"honorificSuffix\": [\n \"M.S.\",\n \"R.D.\",\n \"C.D.N.\",\n \"C.S.C.S.\"\n ],\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/dj-mazzoni\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/dj-mazzoni-rd-cdn-cscs-00a33038\/\",\n \"jobTitle\": \"Medical Reviewer\",\n \"knowsAbout\": \"exercise, drugs, pharmaceutical, health, workout, strength and conditioning, nutrition, dietetics, medicine, medical research, scientific research, scientific method, healthcare, patient care, wellness\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"State University of New York College Oswego\",\n \"D’Youville College\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"image\": {\n\"@type\": \"ImageObject\",\n\"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Phentermine_Thumbnail.jpg?v=1642355362\",\n\"width\": \"2202\",\n\"height\": \"2202\"\n},\n\"citation\": [\n\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Phentermine#section=Mechanism-of-Action\", \n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2687747\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30900410\/\",\n\"https:\/\/illuminatelabs.org\/blogs\/health\/contrave-review\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34236303\/\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK547916\/#:~:text=Common%20side%20effects%20of%20phentermine,acute%20psychosis%20and%20pulmonary%20hypertension.\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/1322448\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31174214\/\",\n\"https:\/\/illuminatelabs.org\/blogs\/health\/why-bpa-free-doesnt-mean-anything\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26330200\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26330200\/\"\n],\n\"mentions\": [{\n \"@type\": \"Thing\",\n \"name\": \"appetite suppression\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"weight loss\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"phentermine side effects\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"high fiber foods\"\n }\n],\n\"datePublished\": \"2021-12-08\",\n\"copyrightHolder\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n},\n\"publisher\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\",\n \"url\": \"https:\/\/illuminatelabs.org\/\",\n \"description\": \"Illuminate Labs is the most transparent supplement company in the U.S., and is a leading publisher of research-based health information.\",\n \"knowsAbout\": \"supplements, science, nutrition, exercise, health, medication, pharmaceutical, wellness, diet, weight loss, medical research\",\n \"publishingPrinciples\": \"https:\/\/illuminatelabs.org\/pages\/editorial-guidelines\",\n \"logo\": {\n \"@type\": \"ImageObject\",\n \"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Illuminate_Labs_Logo.png?v=1641249064\", \n \"width\": 150,\n \"height\": 150\n},\n \"foundingDate\": \"2019-01-30\",\n \"Address\": {\n \"@type\": \"PostalAddress\",\n \"streetAddress\": \"50 Union Street, Unit 9\",\n \"addressLocality\": \"Northampton\",\n \"addressRegion\": \"Massachusetts\",\n \"postalCode\": \"01060\",\n \"addressCountry\": \"US\"\n},\n \"sameAs\": [\n \"https:\/\/www.instagram.com\/illuminatelabs\",\n \"https:\/\/twitter.com\/illuminatelabs\",\n \"https:\/\/www.linkedin.com\/company\/illuminate-labs-supplements\",\n \"https:\/\/www.youtube.com\/channel\/UCpgSJAsIPb-fZ25djtTxBEA\"\n ]\n }\n}\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003e\u003cem\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/em\u003e\u003ci\u003e\u003cspan\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Phentermine_Review_Article_Header_Image_Optimized.png?v=1637550959\" alt=\"\"\u003e\u003c\/span\u003e\u003c\/i\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003e\u003cspan\u003eDisclaimer: None of the information in this article constitutes medical advice, and is just the opinion of the writer(s). We recommend that patients follow their doctor’s guidance in regards to prescription medication.\u003c\/span\u003e\u003c\/i\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cspan class=\"dc\"\u003eP\u003c\/span\u003ehentermine is a prescription medication for weight loss. It’s one of the most popular doctor-prescribed treatments for obesity in the U.S.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn this article we’ll review medical studies on phentermine to determine if it’s likely to be safe and effective for weight loss, as well as provide some natural alternatives which may be as effective with fewer side effects.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eHow Does Phentermine Work?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThis drug works primarily through appetite suppression. When patients take phentermine pills, their levels of norepinephrine increase significantly. This neurotransmitter has indirect effects on hunger.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003ePhentermine is thought to work by inhibiting expression of a neuropeptide which signals the body of hunger, based on \u003c\/span\u003e\u003ca href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Phentermine#section=Mechanism-of-Action\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical research\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e, but the exact mechanism of action isn’t fully understood.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWhat we do know is that phentermine has a similar molecular structure to amphetamine, and has similar effects such as central nervous system stimulation and increased heart rate and blood pressure.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eIs Phentermine Effective for Weight Loss?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMedical research shows that phentermine is effective for weight loss, both short-term and long-term.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2687747\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e on an obese Korean population found that, over 14 weeks, nearly 90% of the patients taking phentermine lost 5% of body weight or more, and 50% of patients taking phentermine lost 10% of body weight or more. This would be categorized as a short-term\u003c\/span\u003e \u003cspan style=\"font-weight: 400;\"\u003etrial.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThese figures were significantly higher than the placebo group, of which 17% lost 5% of body weight or more, and 8.3% lost 10% of body weight or more.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThis study proved that phentermine was around 5 times more effective than placebo.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30900410\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eseparate study\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e analyzed the safety and effectiveness of long-term phentermine use, up to 24 months continuously. It found that patients taking phentermine for over 12 months lost 7.4% more weight than a reference group that wasn’t taking the drug.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe can conclude that phentermine works for weight loss in the context of both short-term and long-term use.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003ePhentermine Side Effects\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003ePhentermine seems relatively safe compared to other weight loss pills we’ve reviewed like \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/contrave-review\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eContrave\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAdverse cardiovascular events like a heart attack would be the biggest concern with a drug of this type, since it primarily acts as a nervous system stimulator. However, the long-term study linked above found no increased CVD or death risk in the phentermine group compared with the reference group. It’s important to note that the study participants were classed as “low-risk” without any pre-existing conditions like high blood pressure.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAnother \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34236303\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003estudy\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e on 932 obese adults who took phentermine for three months found no increased cardiovascular risk.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eSome of the most common side effects of phentermine \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK547916\/#:~:text=Common%20side%20effects%20of%20phentermine,acute%20psychosis%20and%20pulmonary%20hypertension.\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eaccording to LiverTox\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e are: anxiety, palpitations, headache and insomnia. While these side effects aren’t life-threatening, they can be uncomfortable.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eSince phentermine is very similar to amphetamine, the side effect profile is similar. It’s a stimulant, and stimulants can engage the fight-or-flight response in our bodies.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWhile we don’t find the side effects of phentermine to be especially concerning, use of this drug does seem risky compared with natural weight loss treatments which carry no side effect risk.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eNatural Weight Loss Alternatives\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eLifestyle changes are the most effective long-term weight loss strategy, and we want to highlight a unique dietary strategy that’s proven in medical studies but isn’t discussed enough in weight loss review articles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIncreasing intake of dietary fiber has been consistently shown \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/1322448\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ein medical research\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e to predict weight loss. This sounds crazy but it makes sense logically. Fiber is indigestible plant material. This means that it takes up space in the stomach without increasing caloric intake, making people feel full faster.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThis is why eating 1,000 calories of McDonald’s burgers is easy, but eating 1,000 calories of beans, rice and vegetable stir fry is more of a challenge. The healthier meal has much more fiber.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe amazing thing about fiber intake as a weight loss mechanism is that it has a dose-dependent effect (as proven \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31174214\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ein medical data\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e), meaning that the more fiber you eat (to a limit), the more weight you lose.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIt’s best to slowly increase fiber intake because switching from a low-fiber diet to a high-fiber diet can cause some transient gut discomfort like bloating and increased gas.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eFiber can be found in both foods and supplements, and both soluble and insoluble fiber are beneficial for weight loss. Here are some healthy food and supplement options for increasing fiber intake:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eBeans\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e are the ideal healthy high-fiber food, as they’re very cheap and also high in minerals like potassium and magnesium. We recommend buying dried beans over canned beans as they’re cheaper and have no \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/why-bpa-free-doesnt-mean-anything\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eBPA\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e risk from the cans.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eOats\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e have been found to contain a specific type of fiber called beta glucan which can reduce cholesterol. They’re very cheap when purchased in bulk, and we recommend steel-cut oats over instant oats as they have a \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26330200\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003elower glycemic index\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e which means less impact on blood sugar levels.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eBerries\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e are another healthy high-fiber option, and contain high levels of Vitamin C as well. We recommend frozen or fresh berries over dried berries, which have a higher glycemic index.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePsyllium Husk\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is a fiber powder you can purchase as a supplement, and \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26330200\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ehas been associated\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e in medical research with a wide range of beneficial health effects.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAll of these food products can not only help you lose weight, but can make you feel better through improved overall health. We always recommend natural, non-toxic solutions over pharmaceutical drugs as a first measure.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eConclusion\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003ePhentermine has impressive efficacy and safety data, and should help to cause weight loss on average.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThat being said, we don’t recommend it because it’s more expensive and riskier than dietary modifications which can achieve the same goal.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIncreasing fiber intake is the safest, cheapest and most sustainable way to induce weight loss. \u003c\/span\u003e\u003c\/p\u003e","blog_id":49281925193,"author":"Calloway Cook","user_id":26601750601,"published_at":"2021-12-08T12:00:00-05:00","updated_at":"2022-01-16T12:52:56-05:00","summary_html":"\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003e\u003cspan\u003eWe review medical studies on phentermine to determine if it’s likely to be safe and effective for weight loss, as well as provide some natural alternatives which may be as effective with fewer side effects.\u003c\/span\u003e\u003c\/p\u003e","template_suffix":"","handle":"phentermine-review","tags":"_related:weight-loss"}

Phentermine Review: Can The Drug Cause Weight Loss?

Phentermine Review: Can The Drug Cause Weight Loss?


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Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.
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Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.


Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.

Disclaimer: None of the information in this article constitutes medical advice, and is just the opinion of the writer(s). We recommend that patients follow their doctor’s guidance in regards to prescription medication.

Phentermine is a prescription medication for weight loss. It’s one of the most popular doctor-prescribed treatments for obesity in the U.S.

In this article we’ll review medical studies on phentermine to determine if it’s likely to be safe and effective for weight loss, as well as provide some natural alternatives which may be as effective with fewer side effects.

How Does Phentermine Work?

This drug works primarily through appetite suppression. When patients take phentermine pills, their levels of norepinephrine increase significantly. This neurotransmitter has indirect effects on hunger.

Phentermine is thought to work by inhibiting expression of a neuropeptide which signals the body of hunger, based on medical research, but the exact mechanism of action isn’t fully understood.

What we do know is that phentermine has a similar molecular structure to amphetamine, and has similar effects such as central nervous system stimulation and increased heart rate and blood pressure.

Is Phentermine Effective for Weight Loss?

Medical research shows that phentermine is effective for weight loss, both short-term and long-term.

A medical trial on an obese Korean population found that, over 14 weeks, nearly 90% of the patients taking phentermine lost 5% of body weight or more, and 50% of patients taking phentermine lost 10% of body weight or more. This would be categorized as a short-term trial.

These figures were significantly higher than the placebo group, of which 17% lost 5% of body weight or more, and 8.3% lost 10% of body weight or more.

This study proved that phentermine was around 5 times more effective than placebo.

A separate study analyzed the safety and effectiveness of long-term phentermine use, up to 24 months continuously. It found that patients taking phentermine for over 12 months lost 7.4% more weight than a reference group that wasn’t taking the drug.

We can conclude that phentermine works for weight loss in the context of both short-term and long-term use.

Phentermine Side Effects

Phentermine seems relatively safe compared to other weight loss pills we’ve reviewed like Contrave.

Adverse cardiovascular events like a heart attack would be the biggest concern with a drug of this type, since it primarily acts as a nervous system stimulator. However, the long-term study linked above found no increased CVD or death risk in the phentermine group compared with the reference group. It’s important to note that the study participants were classed as “low-risk” without any pre-existing conditions like high blood pressure.

Another study on 932 obese adults who took phentermine for three months found no increased cardiovascular risk.

Some of the most common side effects of phentermine according to LiverTox are: anxiety, palpitations, headache and insomnia. While these side effects aren’t life-threatening, they can be uncomfortable.

Since phentermine is very similar to amphetamine, the side effect profile is similar. It’s a stimulant, and stimulants can engage the fight-or-flight response in our bodies.

While we don’t find the side effects of phentermine to be especially concerning, use of this drug does seem risky compared with natural weight loss treatments which carry no side effect risk.

Natural Weight Loss Alternatives

Lifestyle changes are the most effective long-term weight loss strategy, and we want to highlight a unique dietary strategy that’s proven in medical studies but isn’t discussed enough in weight loss review articles.

Increasing intake of dietary fiber has been consistently shown in medical research to predict weight loss. This sounds crazy but it makes sense logically. Fiber is indigestible plant material. This means that it takes up space in the stomach without increasing caloric intake, making people feel full faster.

This is why eating 1,000 calories of McDonald’s burgers is easy, but eating 1,000 calories of beans, rice and vegetable stir fry is more of a challenge. The healthier meal has much more fiber.

The amazing thing about fiber intake as a weight loss mechanism is that it has a dose-dependent effect (as proven in medical data), meaning that the more fiber you eat (to a limit), the more weight you lose.

It’s best to slowly increase fiber intake because switching from a low-fiber diet to a high-fiber diet can cause some transient gut discomfort like bloating and increased gas.

Fiber can be found in both foods and supplements, and both soluble and insoluble fiber are beneficial for weight loss. Here are some healthy food and supplement options for increasing fiber intake:

Beans are the ideal healthy high-fiber food, as they’re very cheap and also high in minerals like potassium and magnesium. We recommend buying dried beans over canned beans as they’re cheaper and have no BPA risk from the cans.

Oats have been found to contain a specific type of fiber called beta glucan which can reduce cholesterol. They’re very cheap when purchased in bulk, and we recommend steel-cut oats over instant oats as they have a lower glycemic index which means less impact on blood sugar levels.

Berries are another healthy high-fiber option, and contain high levels of Vitamin C as well. We recommend frozen or fresh berries over dried berries, which have a higher glycemic index.

Psyllium Husk is a fiber powder you can purchase as a supplement, and has been associated in medical research with a wide range of beneficial health effects.

All of these food products can not only help you lose weight, but can make you feel better through improved overall health. We always recommend natural, non-toxic solutions over pharmaceutical drugs as a first measure.

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Conclusion

Phentermine has impressive efficacy and safety data, and should help to cause weight loss on average.

That being said, we don’t recommend it because it’s more expensive and riskier than dietary modifications which can achieve the same goal.

Increasing fiber intake is the safest, cheapest and most sustainable way to induce weight loss.





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