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{"id":555824808009,"title":"OmegaXL Review: Why it's Not 20x More Potent Than Fish Oil","created_at":"2021-09-04T20:15:30-04:00","body_html":"\u003cscript type=\"application\/ld+json\"\u003e\/\/ \u003c![CDATA[\n{\n \"@context\": \"https:\/\/schema.org\",\n \"@type\": \"Article\",\n \"headline\": \"OmegaXL Review: Why it's Not 20x More Potent Than Fish Oil\",\n \"keywords\": \"omega xl, omega xl reviews, omega xl review, omega xl ingredients\",\n \"description\": \"Our MD analyzes the formulation of OmegaXL, and also analyzes if their claim of increased potency holds up to medical research. We also review some third-party test results suggesting the product may not be very effective at all.\",\n \"url\": \"https:\/\/illuminatelabs.org\/blogs\/health\/omegaxl-review\",\n\"author\": {\n \"@type\": \"Person\",\n \"name\": \"Taylor Graber MD\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/taylor-graber\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/taylor-j-graber-md-81351642\/\",\n \"jobTitle\": \"Content Partner\",\n \"knowsAbout\": \"medicine, health, anesthesiology, iv therapy, science, drugs, pharmaceutical, medical research, scientific research, medical journals, entrepreneurship, healthcare, orthopedic surgery, biomedical engineering\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"University of California San Diego\",\n \"Arizona University\",\n \"University of Arizona College of Medicine\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"contributor\": {\n \"@type\": \"Person\",\n \"name\": \"Calloway Cook\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/calloway-cook\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/calloway-cook\/\",\n \"jobTitle\": \"President\",\n \"knowsAbout\": \"entrepreneurship, dietary supplements, herbal supplements, eCommerce, medical research\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": \"S.I. Newhouse School of Public Communications at Syracuse University\"\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"editor\": {\n \"@type\": \"Person\",\n \"name\": \"DJ Mazzoni\",\n \"honorificSuffix\": [\n \"M.S.\",\n \"R.D.\",\n \"C.D.N.\",\n \"C.S.C.S.\"\n ],\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/dj-mazzoni\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/dj-mazzoni-rd-cdn-cscs-00a33038\/\",\n \"jobTitle\": \"Medical Reviewer\",\n \"knowsAbout\": \"exercise, drugs, pharmaceutical, health, workout, strength and conditioning, nutrition, dietetics, medicine, medical research, scientific research, scientific method, healthcare, patient care, wellness\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"State University of New York College Oswego\",\n \"D’Youville College\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"image\": {\n\"@type\": \"ImageObject\",\n\"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/OmegaXL_Thumbnail.jpg?v=1642566764\",\n\"width\": \"3142\",\n\"height\": \"3142\"\n},\n\"citation\": [\n\"https:\/\/illuminatelabs.org\/blogs\/health\/fish-oil-supplements-vs-fish-consumption\", \n\"https:\/\/www.fda.gov\/food\/dietary-supplements-guidance-documents-regulatory-information\/dietary-supplement-labeling-guide\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3721214\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17335973\/\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4342081\/\",\n\"https:\/\/www.consumerlab.com\/reviews\/fish-oil-supplements-review\/omega3\/#omegaxl\"\n],\n\"mentions\": [{\n \"@type\": \"Thing\",\n \"name\": \"omega-3\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"Supplement Facts\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"PCSO-524\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"potency\"\n }\n],\n\"datePublished\": \"2021-11-29\",\n\"dateModified\": \"2022-01-18\",\n\"copyrightHolder\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n},\n\"publisher\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\",\n \"url\": \"https:\/\/illuminatelabs.org\/\",\n \"description\": \"Illuminate Labs is the most transparent supplement company in the U.S., and is a leading publisher of research-based health information.\",\n \"knowsAbout\": \"supplements, science, nutrition, exercise, health, medication, pharmaceutical, wellness, diet, weight loss, medical research\",\n \"publishingPrinciples\": \"https:\/\/illuminatelabs.org\/pages\/editorial-guidelines\",\n \"logo\": {\n \"@type\": \"ImageObject\",\n \"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Illuminate_Labs_Logo.png?v=1641249064\", \n \"width\": 150,\n \"height\": 150\n},\n \"foundingDate\": \"2019-01-30\",\n \"Address\": {\n \"@type\": \"PostalAddress\",\n \"streetAddress\": \"50 Union Street, Unit 9\",\n \"addressLocality\": \"Northampton\",\n \"addressRegion\": \"Massachusetts\",\n \"postalCode\": \"01060\",\n \"addressCountry\": \"US\"\n},\n \"sameAs\": [\n \"https:\/\/www.instagram.com\/illuminatelabs\",\n \"https:\/\/twitter.com\/illuminatelabs\",\n \"https:\/\/www.linkedin.com\/company\/illuminate-labs-supplements\",\n \"https:\/\/www.youtube.com\/channel\/UCpgSJAsIPb-fZ25djtTxBEA\"\n ]\n }\n}\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/OmegaXL_Review_Article_Header_Image_Optimized_5_495d4628-a966-41f4-92ac-e68cbdadbd58.png?v=1642567338\" alt=\"\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cspan class=\"dc\"\u003eO\u003c\/span\u003emegaXL is a fish oil product which makes some aggressive health claims: the brand claims their product is 20x more potent than standard fish oil. We know from medical research that fish oil, and specifically the \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/fish-oil-supplements-vs-fish-consumption\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eomega-3\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e fatty acids it contains, are beneficial for human health. But OmegaXL’s claim seems to be questionable at face value.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn this article, we’ll analyze the formulation of OmegaXL to determine if it’s likely to be effective, and also analyze if their claim of increased potency holds up to medical research. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe'll also overview some third-party test results suggesting the product may not be very effective at all.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eOmegaXL Ingredient Review\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cb\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/OmegaXLIngredientsOptimized_914347ae-2b55-4bee-afa2-ef28d03cf494.png?v=1630801860\" alt=\"OmegaXL Supplement Facts label\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOmegaXL doesn’t publish a Supplement Facts label on their website. Not only is this arguably in violation of \u003c\/span\u003e\u003ca href=\"https:\/\/www.fda.gov\/food\/dietary-supplements-guidance-documents-regulatory-information\/dietary-supplement-labeling-guide\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eFDA labeling requirements\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e, but it’s a clear red flag that a company doesn't respect their consumers.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWhy would a dietary supplements company not tell their consumers what’s in the product they’re selling, and at what dosage, if not to be deceptive?\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThankfully we can get the Supplement Facts label (shown above) from Amazon because Amazon has stringent listing requirements.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOmegaXL contains a proprietary (prop) blend with a total dosage of 300 mg. Prop blends are another red flag for consumers about the ethics of a company. Instead of just listing the exact dosage of every ingredient, companies will just list the dosage of the entire blend, which can prevent consumers and researchers from determining if the product is likely to be effective.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA 300 mg dosage for this product seems very low, given that we know from existing research on fish oil that usually doses over 1 gram (g) is used in medical research. If the entire dosage in OmegaXL is less than 33% of what appears to be the effective dose of fish oil, it’s a bad sign since fish oil is just one of three ingredients in the prop blend, meaning the actual dose of fish oil is necessarily less than 300 mg.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eQuestionable Medical Studies Backing OmegaXL\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOmegaXL uses a patented fish oil extract called “PCSO-524”. \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3721214\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eOne medical study\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e on this patented oil did find it to be more effective than fish oil for treating arthritis pain, but we believe the study was designed poorly. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe study was funded by the company which makes the patented fish oil, and the regular fish oil used for comparison seems extremely underdosed at 150 mg\/day. Since \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17335973\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emost medical research\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e on regular fish oil for pain uses dosages well over 1 g\/day, it appears to us that the private company funding the trial intentionally set it up to fail so their patented oil looked superior.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4342081\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eAnother study\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e on the patented fish oil in OmegaXL was also funded by the same holding company Pharmalink International Ltd., also also appears intentionally poorly designed. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe second study tested PCSO-524 supplementation on inflammation in muscle post-exercise, and found it to be a useful therapeutic agent, but the patented fish oil was compared to olive oil instead of regular fish oil! This provides zero useful insight. Also, the dosage used was 1200 mg\/day, or 4 times the amount in the entire OmegaXL capsule (which contains other ingredients too).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOverall we believe the research backing this product is so poorly designed as to be essentially worthless. PCSO-524 may be more effective than placebo, but we don’t believe the medical trials, which had significant bias, proved it was more effective than regular fish oil supplementation at an effective dose.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eUnproven Health Claims\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOmegaXL’s core claim is that their product is 20x more potent than standard fish oil. This is a strange claim to make with literally zero published proof on their website. Just saying something doesn't make it true.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe don’t even know how the company is assessing “potency” of a fish oil: is it in terms of EPA\/DHA which are the active fatty acid compounds in fish oil? Because if so there is zero proof this product contains such a high potency relative to standard fish oil.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe have no idea what they’re referencing with this health claim, and the company provides no backing for it, so we can assume it’s entirely made up for marketing and inaccurate.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe can conclude by how underdosed OmegaXL is that it's necessarily ineffective.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eBad Third-Party Testing Results\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eConsumerLab is an independent laboratory which publishes test results of supplements. \u003c\/span\u003e\u003ca href=\"https:\/\/www.consumerlab.com\/reviews\/fish-oil-supplements-review\/omega3\/#omegaxl\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eThey tested OmegaXL\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e and found very few omega fatty acids at all, and concluded that the product had a “chemical profile similar to olive oil”.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThis is another red flag and bad sign for OmegaXL, because ConsumerLab, unlike studies funded by the company which owns the patented fish oil contained in OmegaXL, has no apparent biases or reason to misreport testing. They’re the most accurate third-party publisher in our opinion.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIt appears from their test results that OmegaXL isn't primarily made of fish oil at all, but is cut with cheaper oils so the company can make higher profits.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eConclusion\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe haven’t seen any convincing medical evidence that OmegaXL is more effective or potent than standard fish oil. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOmegaXL is a company which makes very questionable health claims (which we would argue are intentionally deceptive), doesn’t publish ingredients on their site, and cites medical research with extremely strong biases and poor design. Third-party testing found that their product didn't even chemically resemble fish oil.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe do not recommend OmegaXL or any of the products they sell, and would recommend avoiding this company entirely. There are too many red flags and questionable business practices in our opinion.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe recommend that consumers considering fish oil benefits use standard fish oil supplements or consume fish (in moderation) high in omega-3 fatty acids like sardines. Either of these options is likely to be more effective and cheaper than buying OmegaXL.\u003c\/span\u003e\u003c\/p\u003e","blog_id":49281925193,"author":"Calloway Cook","user_id":26601750601,"published_at":"2021-11-29T12:00:25-05:00","updated_at":"2022-01-18T23:43:51-05:00","summary_html":"\u003cmeta charset=\"utf-8\"\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003e\u003cspan\u003eWe analyze the formulation of OmegaXL, and also analyze if their claim of increased potency holds up to medical research. We also review some third-party test results suggesting the product may not be very effective at all.\u003c\/span\u003e\u003c\/p\u003e","template_suffix":"","handle":"omegaxl-review","tags":"_related:fish-oil, _related:inflammation"}

OmegaXL Review: Why it's Not 20x More Potent Than Fish Oil

OmegaXL Review: Why it's Not 20x More Potent Than Fish Oil


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Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.
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Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.


Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.

OmegaXL is a fish oil product which makes some aggressive health claims: the brand claims their product is 20x more potent than standard fish oil. We know from medical research that fish oil, and specifically the omega-3 fatty acids it contains, are beneficial for human health. But OmegaXL’s claim seems to be questionable at face value.

In this article, we’ll analyze the formulation of OmegaXL to determine if it’s likely to be effective, and also analyze if their claim of increased potency holds up to medical research.

We'll also overview some third-party test results suggesting the product may not be very effective at all.

OmegaXL Ingredient Review

OmegaXL Supplement Facts label

OmegaXL doesn’t publish a Supplement Facts label on their website. Not only is this arguably in violation of FDA labeling requirements, but it’s a clear red flag that a company doesn't respect their consumers.

Why would a dietary supplements company not tell their consumers what’s in the product they’re selling, and at what dosage, if not to be deceptive?

Thankfully we can get the Supplement Facts label (shown above) from Amazon because Amazon has stringent listing requirements.

OmegaXL contains a proprietary (prop) blend with a total dosage of 300 mg. Prop blends are another red flag for consumers about the ethics of a company. Instead of just listing the exact dosage of every ingredient, companies will just list the dosage of the entire blend, which can prevent consumers and researchers from determining if the product is likely to be effective.

A 300 mg dosage for this product seems very low, given that we know from existing research on fish oil that usually doses over 1 gram (g) is used in medical research. If the entire dosage in OmegaXL is less than 33% of what appears to be the effective dose of fish oil, it’s a bad sign since fish oil is just one of three ingredients in the prop blend, meaning the actual dose of fish oil is necessarily less than 300 mg.

Questionable Medical Studies Backing OmegaXL

OmegaXL uses a patented fish oil extract called “PCSO-524”. One medical study on this patented oil did find it to be more effective than fish oil for treating arthritis pain, but we believe the study was designed poorly. 

The study was funded by the company which makes the patented fish oil, and the regular fish oil used for comparison seems extremely underdosed at 150 mg/day. Since most medical research on regular fish oil for pain uses dosages well over 1 g/day, it appears to us that the private company funding the trial intentionally set it up to fail so their patented oil looked superior.

Another study on the patented fish oil in OmegaXL was also funded by the same holding company Pharmalink International Ltd., also also appears intentionally poorly designed. 

The second study tested PCSO-524 supplementation on inflammation in muscle post-exercise, and found it to be a useful therapeutic agent, but the patented fish oil was compared to olive oil instead of regular fish oil! This provides zero useful insight. Also, the dosage used was 1200 mg/day, or 4 times the amount in the entire OmegaXL capsule (which contains other ingredients too).

Overall we believe the research backing this product is so poorly designed as to be essentially worthless. PCSO-524 may be more effective than placebo, but we don’t believe the medical trials, which had significant bias, proved it was more effective than regular fish oil supplementation at an effective dose.

Unproven Health Claims

OmegaXL’s core claim is that their product is 20x more potent than standard fish oil. This is a strange claim to make with literally zero published proof on their website. Just saying something doesn't make it true.

We don’t even know how the company is assessing “potency” of a fish oil: is it in terms of EPA/DHA which are the active fatty acid compounds in fish oil? Because if so there is zero proof this product contains such a high potency relative to standard fish oil.

We have no idea what they’re referencing with this health claim, and the company provides no backing for it, so we can assume it’s entirely made up for marketing and inaccurate.

We can conclude by how underdosed OmegaXL is that it's necessarily ineffective.

Bad Third-Party Testing Results

ConsumerLab is an independent laboratory which publishes test results of supplements. They tested OmegaXL and found very few omega fatty acids at all, and concluded that the product had a “chemical profile similar to olive oil”.

This is another red flag and bad sign for OmegaXL, because ConsumerLab, unlike studies funded by the company which owns the patented fish oil contained in OmegaXL, has no apparent biases or reason to misreport testing. They’re the most accurate third-party publisher in our opinion.

It appears from their test results that OmegaXL isn't primarily made of fish oil at all, but is cut with cheaper oils so the company can make higher profits.

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Conclusion

We haven’t seen any convincing medical evidence that OmegaXL is more effective or potent than standard fish oil. 

OmegaXL is a company which makes very questionable health claims (which we would argue are intentionally deceptive), doesn’t publish ingredients on their site, and cites medical research with extremely strong biases and poor design. Third-party testing found that their product didn't even chemically resemble fish oil.

We do not recommend OmegaXL or any of the products they sell, and would recommend avoiding this company entirely. There are too many red flags and questionable business practices in our opinion.

We recommend that consumers considering fish oil benefits use standard fish oil supplements or consume fish (in moderation) high in omega-3 fatty acids like sardines. Either of these options is likely to be more effective and cheaper than buying OmegaXL.





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