{"id":557048037449,"title":"Detoxify Mega Clean Review: Can It Reduce Toxins?","created_at":"2022-10-16T12:27:27-04:00","body_html":"\u003cscript type=\"application\/ld+json\"\u003e\/\/ \u003c![CDATA[\n{\n \"@context\": \"https:\/\/schema.org\",\n \"@type\": \"Article\",\n \"headline\": \"Detoxify Mega Clean Review: Can It Reduce Toxins?\",\n \"keywords\": \"mega clean, detoxify mega clean, detoxify mega clean reviews, mega clean detoxify, detoxify herbal cleanse mega clean reviews, mega clean detox drink by detoxify, mega clean detox drink\",\n \"description\": \"Our research team reviews every ingredient in Detoxify Mega Clean based on medical studies to give our take on whether it's likely to be effective. We share concerns we have about herbal detoxification generally, and highlight some questionable health claims made by Detoxify.\",\n \"url\": \"https:\/\/illuminatelabs.org\/blogs\/health\/detoxify-mega-clean-review\",\n\"author\": {\n \"@type\": \"Person\",\n \"name\": \"Calloway Cook\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/calloway-cook\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/calloway-cook\/\",\n \"jobTitle\": \"President\",\n \"knowsAbout\": \"entrepreneurship, dietary supplements, herbal supplements, eCommerce, medical research\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": \"S.I. Newhouse School of Public Communications at Syracuse University\"\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"editor\": {\n \"@type\": \"Person\",\n \"name\": \"DJ Mazzoni\",\n \"honorificSuffix\": [\n \"M.S.\",\n \"R.D.\",\n \"C.D.N.\",\n \"C.S.C.S.\"\n ],\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/dj-mazzoni\",\n \"sameAs\": [\n \"https:\/\/www.linkedin.com\/in\/dj-mazzoni-rd-cdn-cscs-00a33038\/\",\n \"http:\/\/djmazzoni.com\/\"\n ],\n \"jobTitle\": \"Medical Reviewer\",\n \"knowsAbout\": \"exercise, drugs, pharmaceutical, health, workout, strength and conditioning, nutrition, dietetics, medicine, medical research, scientific research, scientific method, healthcare, patient care, wellness\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"State University of New York College Oswego\",\n \"D’Youville College\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"image\": {\n\"@type\": \"ImageObject\",\n\"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Detoxify_Mega_Clean_Thumbnail.png?v=1665947683\",\n\"width\": \"3215\",\n\"height\": \"3215\"\n},\n\"citation\": [\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31246081\/\", \n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20564545\/\",\n\"https:\/\/illuminatelabs.org\/blogs\/health\/high-voltage-detox-review\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16835878\/\",\n\"https:\/\/www.fakespot.com\/product\/detoxify-detoxify-mega-clean-trop-32-fz\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19854235\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27644601\/\"\n],\n\"mentions\": [{\n \"@type\": \"Thing\",\n \"name\": \"added sugar\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"milk thistle\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"uva ursi\"\n },\n {\n \"@type\": \"Brand\",\n \"name\": \"TED talk\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Fakespot\"\n }\n],\n\"datePublished\": \"2022-10-16\",\n\"copyrightHolder\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n},\n\"publisher\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\",\n \"url\": \"https:\/\/illuminatelabs.org\/\",\n \"description\": \"Illuminate Labs is the most transparent supplement company in the U.S., and is a leading publisher of research-based health information.\",\n \"knowsAbout\": \"supplements, science, nutrition, exercise, health, medication, pharmaceutical, wellness, diet, weight loss, medical research\",\n \"publishingPrinciples\": \"https:\/\/illuminatelabs.org\/pages\/editorial-guidelines\",\n \"memberOf\": [\n {\n \"@type\": \"Organization\",\n \"name\": \"U.S. Chamber of Commerce\",\n \"url\": \"https:\/\/www.uschamber.com\/\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Certified B Corp\",\n \"url\": \"https:\/\/www.bcorporation.net\/en-us\/\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Natural Products Association\",\n \"url\": \"https:\/\/www.npanational.org\/\"\n }\n ],\n \"logo\": {\n \"@type\": \"ImageObject\",\n \"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Illuminate_Labs_Favicon_48x48_7595c3cc-e27b-47b8-a4fe-edcc7ed9b29a.png?v=1666502785\", \n \"width\": 48,\n \"height\": 48\n},\n \"foundingDate\": \"2019-01-30\",\n \"sameAs\": [\n \"https:\/\/www.instagram.com\/illuminatelabs\",\n \"https:\/\/twitter.com\/illuminatelabs\",\n \"https:\/\/www.linkedin.com\/company\/illuminate-labs-supplements\",\n \"https:\/\/www.youtube.com\/channel\/UCpgSJAsIPb-fZ25djtTxBEA\"\n ]\n }\n}\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003cp\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Detoxify_Mega_Clean_Review_Article_Header_Image_Optimized_ce8da64b-21a6-4873-8b34-5b8d845f7a92.png?v=1665937586\" alt=\"\"\u003e\u003c\/span\u003e\u003c\/i\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eDisclaimer: None of the information in this article constitutes medical advice, and is just the opinion of the writer(s). We recommend that patients follow their doctor’s guidance in regard to detoxification.\u003c\/span\u003e\u003c\/i\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cspan class=\"dc\"\u003eM\u003c\/span\u003eega Clean is a liquid herbal supplement sold by a brand called Detoxify. The product costs $25.25 for a single serving (which is one bottle) which is a shockingly high price. Detoxify claims that their supplement will “help your body naturally cleanse your urinary, circulatory and digestive systems in a delicious, single herbal cleansing drink.”\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eBut can a liquid herb blend actually detoxify the body, or is this just a marketing claim? Does the supplement contain any ingredients proven in medical research to be effective for detoxification? Does it contain any unhealthy additive ingredients.\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn this article we’ll answer all of these questions and more as we review the ingredients in Detoxify Mega Clean based on published medical research, and give our take on whether or not the supplement is likely to be effective.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMega Clean contains a large number of active ingredients, so we’ll break our ingredient review down into two sections: vitamin \u0026amp; mineral blend, and herbal blend.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eIngredient Review - Vitamin \u0026amp; Mineral Blend\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Detoxify_Mega_Clean_Vitamin_Mineral_Blend_Optimized_45641b5e-3751-49c6-ba33-bc4d40bed2a1.png?v=1665947366\" alt=\"Detoxify Mega Clean vitamin and mineral blend ingredients\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe blend with the largest number of ingredients in Mega Clean is the vitamin and mineral blend. It contains 18 added vitamins and minerals, such as \u003c\/span\u003e\u003cb\u003eriboflavin\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e, \u003c\/span\u003e\u003cb\u003eselenium\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e and \u003c\/span\u003e\u003cb\u003evitamin B12\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe have not come across any medical evidence that added vitamins and minerals provide detoxification benefits to the body, nor does Detoxify cite any on their product page, so we will consider this entire blend likely ineffective. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMega Clean contains 42 grams (g) of \u003c\/span\u003e\u003cb\u003eadded sugar\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e. This is nearly twice as much sugar as a regular-sized Coca-Cola and is an absurd amount for a “health” drink to have in our opinion.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe know from decades of \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31246081\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical studies\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e that added sugar consumption is associated with a range of negative health outcomes such as increased diabetes risk, increased obesity risk and increased risk of cardiovascular disease. We recommend avoiding added sugar intake entirely if possible (or limiting its consumption as much as possible) so we would recommend avoiding this drink based on this fact alone.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThere is not one ingredient in this blend that we consider likely effective for supplemental detoxification. It’s essentially a multivitamin with a significant amount of added sugar.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eIngredient Review - Herbal Blend\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Detoxify_Mega_Clean_Herbal_Blend_Optimized_49bc130a-f8ad-41f8-b615-5f13871425b1.png?v=1665947387\" alt=\"Detoxify Mega Clean herbal blend ingredients\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMega Clean does contain some herbal ingredients that have been studied in relation to detoxification.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eMilk thistle\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e has been documented in a \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20564545\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in the Phytotherapy Research journal to reduce the effects of liver injury, and its active chemical compound silymarin “may act as a toxin blockade agent” that inhibits toxins from binding to cell membrane receptors in the liver.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eUva ursi leaf extract\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is an herbal extract derived from an evergreen shrub that may be effective for treating kidney stones, as we detailed in our \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/high-voltage-detox-review\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eHigh Voltage Detox reviews\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e article. However, kidney stones aren’t always caused by toxins and are often caused by poor diet or medical conditions.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCitrus pectin\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is included in Mega Clean at a dose of 173 milligrams (mg), but our research indicates that this ingredient is a gelling agent, while modified citrus pectin is the fibrous material sourced from citrus plant pulps that’s been studied for detoxification support. A 2006 \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16835878\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e found that intake of 15,000 mg of modified citrus pectin increased urinary excretion of toxic elements. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOur research suggests citrus pectin and modified citrus pectin are different ingredients with different biological effects, so we do not consider citrus pectin likely to be effective. However, we urge Detoxify to clarify whether there is a difference and if so, why they chose to use citrus pectin.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe cannot identify any medical studies suggesting that other herbal ingredients in this blend are effective.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eOverall we consider this blend potentially effective for detoxification support, however we cannot recommend it because the ingredients are published in a proprietary “prop” blend which means only the total dose and not the individual ingredient doses are listed.\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eConsumers require individual ingredient doses to determine if any ingredient in a blend is safe and effectively-dosed, which is why we always recommend avoiding supplements that use a prop blend unless that supplement has been independently studied in clinical trials.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eAre Detox Supplements Safe?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe generally recommend that consumers avoid dietary supplements promoted for detoxification, because we haven’t come across much medical research suggesting that healthy adults need supplemental detoxification.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe liver and kidneys detoxify the blood very efficiently (that’s their function), and we don’t consider it logical to treat medical conditions which require detoxification with dietary supplements.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAn example of a health condition that may require a medically-assisted, supplemental detoxification protocol is liver disease. We would strongly recommend a patient with liver disease to seek medical assistance rather than take sugary dietary supplements to treat their condition.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOur overall point is that the category of health conditions that require external detoxification tend to be quite serious, and poorly-suited to over-the-counter (OTC) treatments.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn the 3-minute TED talk below, a doctor explains how the body naturally detoxes and why cleanses don’t work:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ciframe width=\"560\" height=\"315\" src=\"https:\/\/www.youtube.com\/embed\/DESCcjSQSKY\" title=\"YouTube video player\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen=\"\"\u003e\u003c\/iframe\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eQuestionable Health Claims\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThere are a number of questionable health claims on the Detoxify website.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Detoxify_Mega_Clean_Questionable_Health_Claim_1_Optimized_f7dc70f5-39a2-4e39-a8d7-880e525fd5cc.png?v=1665947126\" alt=\"Detoxify Mega Clean questionable health claim 1\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eDetoxify claims that the “formula behind this product has been time tested to help rid your body of toxins at a moment’s notice.” There is no citation for this claim. We cannot find any medical evidence that this specific formula has been tested in clinical trials.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Detoxify_Mega_Clean_Questionable_Health_Claim_2_Optimized.png?v=1665947147\" alt=\"Detoxify Mega Clean questionable health claim 2\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe brand also claims that “Mega Clean is formulated to work indiscriminately on any toxin in your body.” There is no citation for this claim. We consider this to be an unscientific claim given that most clinical research on exogenous detoxification involves a specific type of toxin (like heavy metal, pesticide, etc).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eWe suggest that consumers entirely disregard health claims made by supplement companies that provide no proof of such claims\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e, and we consider this to be a sign of a low-quality brand.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eDetoxify Mega Clean Real Customer Reviews\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMega Clean is sold on Amazon which is a more objective resource for customer reviews than a brand’s website in our opinion. The detox drink has a 3.8 out of 5 star rating with over 6,000 total reviews.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIt receives a “D” grade \u003c\/span\u003e\u003ca href=\"https:\/\/www.fakespot.com\/product\/detoxify-detoxify-mega-clean-trop-32-fz\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eon Fakespot\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e, which is a software tool that detects potentially fake Amazon reviews. Fakespot’s “Adjusted Rating” is 2 out of 5 stars.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe top positive review from a verified purchaser is written by a user named “Zoe Mack” who claims the drink helped her pass a urine test:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e“For the test- I waited around 3 hours after drinking before I tested the first time. Tested negative. Waited another hour and a half for the second test and still tested negative. I had my official test today, I quit smoking around 4 weeks ago and still tested positive. Been taking detox pills, which has semi helped (I think).”\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe top negative review from a verified purchaser comes from a user named “Oblivion” who claim the drink was ineffective for passing a urine test:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e“Perhaps my weight and diet compromised my results but as it stands, this method of clensing failed to produce any negative test results. I have been off of Delta 9 for 56 days, everyday smoker prior. Have dabled in Delta 12 and 8 about 48 days prior. \u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eI moderatly fasted prior to beginning the clense. 6 pre clense pills taken at varying times the day before clensing along with recommended water intake. I tested throughout the entire process yet no change was detected. Instructions were followed thoroughly but no other dietary changes were made during which may have adversely affected the clensing but should not have been a large factor considering metabolism.”\u003c\/b\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eResearch-Backed Liver Support Plant\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Moringa_Leaf_Image.jpg?v=1665937634\" alt=\"moringa leaf\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe don't recommend the use of food products or supplements to \"cleanse\" or \"remove toxins\" from the body as stated above. However, there are compounds which can naturally support the body's own detoxification processes for consumers intent on doing so.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe liver and kidneys detoxify the body, and moringa leaf is a plant which has been found in medical research to optimize and enhance the body's innate detoxification pathways.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19854235\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e on animals, published in the \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eFood and Chemical Toxicology\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e journal, found that \u003c\/span\u003e\u003cstrong\u003emoringa leaf reduced liver damage and improved symptoms of liver fibrosis.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27644601\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in 2016 reviewed tens of individual trials on moringa leaf and concluded that the plant may be effective for chemoprevention (reducing risk of cancer development) due to its ability to support natural detoxification pathways.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe are not suggesting that moringa leaf should be used to treat any specific medical condition; we're just highlighting early research suggesting that this plant may be beneficial to organ systems that detoxify the human body, and may be used in a preventative manner. Moringa is a food product and not a supplement.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca rel=\"sponsored\" href=\"https:\/\/shrsl.com\/3o10t\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eApothékary Moringa Powder\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e is the moringa product we recommend, because it has one single ingredient (moringa powder), and no questionable additives. Moringa powder can be added to smoothies, yogurt or just mixed into water or tea.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eInterested consumers can check out Apothékary Moringa Powder \u003c\/span\u003e\u003ca rel=\"sponsored\" href=\"https:\/\/shrsl.com\/3o10t\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eat this link\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eConclusion\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWhile Detoxify Mega Clean may provide some detoxification benefits due to the inclusion of milk thistle and uva ursi leaf extract, we do not recommend the supplement overall because it has 42 g of added sugar. This is an unacceptable and unhealthy amount in our opinion for a product branded as a “health” drink.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eFurther, it’s impossible to determine whether the herbal ingredients are effectively dosed, because they’re included in a prop blend, which means that Detoxify fails to publish individual ingredient doses.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe do not believe that the average consumer has a need for detox supplements, and we find the claims made by most detox supplement brands, including Detoxify, to be highly questionable and arguably unscientific.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eDetoxify Mega Clean has relatively unimpressive consumer reviews on Amazon.\u003c\/span\u003e\u003c\/p\u003e","blog_id":49281925193,"author":"Calloway Cook","user_id":26601750601,"published_at":"2022-10-16T15:17:39-04:00","updated_at":"2022-10-23T02:45:56-04:00","summary_html":"We review every ingredient in Detoxify Mega Clean based on medical studies to give our take on whether it's likely to be effective. We share concerns we have about herbal detoxification generally, and highlight some questionable health claims made by Detoxify.","template_suffix":"","handle":"detoxify-mega-clean-review","tags":"_related:detox"}

Detoxify Mega Clean Review: Can It Reduce Toxins?

Detoxify Mega Clean Review: Can It Reduce Toxins?


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Disclaimer: None of the information in this article constitutes medical advice, and is just the opinion of the writer(s). We recommend that patients follow their doctor’s guidance in regard to detoxification.

Mega Clean is a liquid herbal supplement sold by a brand called Detoxify. The product costs $25.25 for a single serving (which is one bottle) which is a shockingly high price. Detoxify claims that their supplement will “help your body naturally cleanse your urinary, circulatory and digestive systems in a delicious, single herbal cleansing drink.”

But can a liquid herb blend actually detoxify the body, or is this just a marketing claim? Does the supplement contain any ingredients proven in medical research to be effective for detoxification? Does it contain any unhealthy additive ingredients.

In this article we’ll answer all of these questions and more as we review the ingredients in Detoxify Mega Clean based on published medical research, and give our take on whether or not the supplement is likely to be effective.

Mega Clean contains a large number of active ingredients, so we’ll break our ingredient review down into two sections: vitamin & mineral blend, and herbal blend.

Ingredient Review - Vitamin & Mineral Blend

Detoxify Mega Clean vitamin and mineral blend ingredients

The blend with the largest number of ingredients in Mega Clean is the vitamin and mineral blend. It contains 18 added vitamins and minerals, such as riboflavin, selenium and vitamin B12.

We have not come across any medical evidence that added vitamins and minerals provide detoxification benefits to the body, nor does Detoxify cite any on their product page, so we will consider this entire blend likely ineffective. 

Mega Clean contains 42 grams (g) of added sugar. This is nearly twice as much sugar as a regular-sized Coca-Cola and is an absurd amount for a “health” drink to have in our opinion.

We know from decades of medical studies that added sugar consumption is associated with a range of negative health outcomes such as increased diabetes risk, increased obesity risk and increased risk of cardiovascular disease. We recommend avoiding added sugar intake entirely if possible (or limiting its consumption as much as possible) so we would recommend avoiding this drink based on this fact alone.

There is not one ingredient in this blend that we consider likely effective for supplemental detoxification. It’s essentially a multivitamin with a significant amount of added sugar.

Ingredient Review - Herbal Blend

Detoxify Mega Clean herbal blend ingredients

Mega Clean does contain some herbal ingredients that have been studied in relation to detoxification.

Milk thistle has been documented in a medical review published in the Phytotherapy Research journal to reduce the effects of liver injury, and its active chemical compound silymarin “may act as a toxin blockade agent” that inhibits toxins from binding to cell membrane receptors in the liver.

Uva ursi leaf extract is an herbal extract derived from an evergreen shrub that may be effective for treating kidney stones, as we detailed in our High Voltage Detox reviews article. However, kidney stones aren’t always caused by toxins and are often caused by poor diet or medical conditions.

Citrus pectin is included in Mega Clean at a dose of 173 milligrams (mg), but our research indicates that this ingredient is a gelling agent, while modified citrus pectin is the fibrous material sourced from citrus plant pulps that’s been studied for detoxification support. A 2006 clinical trial found that intake of 15,000 mg of modified citrus pectin increased urinary excretion of toxic elements. 

Our research suggests citrus pectin and modified citrus pectin are different ingredients with different biological effects, so we do not consider citrus pectin likely to be effective. However, we urge Detoxify to clarify whether there is a difference and if so, why they chose to use citrus pectin.

We cannot identify any medical studies suggesting that other herbal ingredients in this blend are effective.

Overall we consider this blend potentially effective for detoxification support, however we cannot recommend it because the ingredients are published in a proprietary “prop” blend which means only the total dose and not the individual ingredient doses are listed.

Consumers require individual ingredient doses to determine if any ingredient in a blend is safe and effectively-dosed, which is why we always recommend avoiding supplements that use a prop blend unless that supplement has been independently studied in clinical trials.

Are Detox Supplements Safe?

We generally recommend that consumers avoid dietary supplements promoted for detoxification, because we haven’t come across much medical research suggesting that healthy adults need supplemental detoxification.

The liver and kidneys detoxify the blood very efficiently (that’s their function), and we don’t consider it logical to treat medical conditions which require detoxification with dietary supplements.

An example of a health condition that may require a medically-assisted, supplemental detoxification protocol is liver disease. We would strongly recommend a patient with liver disease to seek medical assistance rather than take sugary dietary supplements to treat their condition.

Our overall point is that the category of health conditions that require external detoxification tend to be quite serious, and poorly-suited to over-the-counter (OTC) treatments.

In the 3-minute TED talk below, a doctor explains how the body naturally detoxes and why cleanses don’t work:

Questionable Health Claims

There are a number of questionable health claims on the Detoxify website.

Detoxify Mega Clean questionable health claim 1

Detoxify claims that the “formula behind this product has been time tested to help rid your body of toxins at a moment’s notice.” There is no citation for this claim. We cannot find any medical evidence that this specific formula has been tested in clinical trials.

Detoxify Mega Clean questionable health claim 2

The brand also claims that “Mega Clean is formulated to work indiscriminately on any toxin in your body.” There is no citation for this claim. We consider this to be an unscientific claim given that most clinical research on exogenous detoxification involves a specific type of toxin (like heavy metal, pesticide, etc).

We suggest that consumers entirely disregard health claims made by supplement companies that provide no proof of such claims, and we consider this to be a sign of a low-quality brand.

Detoxify Mega Clean Real Customer Reviews

Mega Clean is sold on Amazon which is a more objective resource for customer reviews than a brand’s website in our opinion. The detox drink has a 3.8 out of 5 star rating with over 6,000 total reviews.

It receives a “D” grade on Fakespot, which is a software tool that detects potentially fake Amazon reviews. Fakespot’s “Adjusted Rating” is 2 out of 5 stars.

The top positive review from a verified purchaser is written by a user named “Zoe Mack” who claims the drink helped her pass a urine test:

“For the test- I waited around 3 hours after drinking before I tested the first time. Tested negative. Waited another hour and a half for the second test and still tested negative. I had my official test today, I quit smoking around 4 weeks ago and still tested positive. Been taking detox pills, which has semi helped (I think).”

The top negative review from a verified purchaser comes from a user named “Oblivion” who claim the drink was ineffective for passing a urine test:

“Perhaps my weight and diet compromised my results but as it stands, this method of clensing failed to produce any negative test results. I have been off of Delta 9 for 56 days, everyday smoker prior. Have dabled in Delta 12 and 8 about 48 days prior. 

I moderatly fasted prior to beginning the clense. 6 pre clense pills taken at varying times the day before clensing along with recommended water intake. I tested throughout the entire process yet no change was detected. Instructions were followed thoroughly but no other dietary changes were made during which may have adversely affected the clensing but should not have been a large factor considering metabolism.”

Research-Backed Liver Support Plant

moringa leaf

We don't recommend the use of food products or supplements to "cleanse" or "remove toxins" from the body as stated above. However, there are compounds which can naturally support the body's own detoxification processes for consumers intent on doing so.

The liver and kidneys detoxify the body, and moringa leaf is a plant which has been found in medical research to optimize and enhance the body's innate detoxification pathways.

A clinical trial on animals, published in the Food and Chemical Toxicology journal, found that moringa leaf reduced liver damage and improved symptoms of liver fibrosis.

A medical review published in 2016 reviewed tens of individual trials on moringa leaf and concluded that the plant may be effective for chemoprevention (reducing risk of cancer development) due to its ability to support natural detoxification pathways.

We are not suggesting that moringa leaf should be used to treat any specific medical condition; we're just highlighting early research suggesting that this plant may be beneficial to organ systems that detoxify the human body, and may be used in a preventative manner. Moringa is a food product and not a supplement.

Apothékary Moringa Powder is the moringa product we recommend, because it has one single ingredient (moringa powder), and no questionable additives. Moringa powder can be added to smoothies, yogurt or just mixed into water or tea.

Interested consumers can check out Apothékary Moringa Powder at this link.

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Conclusion

While Detoxify Mega Clean may provide some detoxification benefits due to the inclusion of milk thistle and uva ursi leaf extract, we do not recommend the supplement overall because it has 42 g of added sugar. This is an unacceptable and unhealthy amount in our opinion for a product branded as a “health” drink.

Further, it’s impossible to determine whether the herbal ingredients are effectively dosed, because they’re included in a prop blend, which means that Detoxify fails to publish individual ingredient doses.

We do not believe that the average consumer has a need for detox supplements, and we find the claims made by most detox supplement brands, including Detoxify, to be highly questionable and arguably unscientific.

Detoxify Mega Clean has relatively unimpressive consumer reviews on Amazon.




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