{"id":606986240306,"title":"Jublia Review: Does Prescription Antifungal Cream Work?","created_at":"2024-01-23T13:06:17-05:00","body_html":"\u003cscript type=\"application\/ld+json\"\u003e\/\/ \u003c![CDATA[\n{\n \"@context\": \"https:\/\/schema.org\",\n \"@type\": \"Article\",\n \"headline\": \"Jublia Review: Does Prescription Antifungal Cream Work?\",\n \"keywords\": \"jublia, jublia review, jublia reviews, jublia generic, jublia toenail fungus, jublia side effects\",\n \"url\": \"https:\/\/illuminatelabs.org\/blogs\/health\/jublia-review\",\n\"author\": {\n \"@type\": \"Person\",\n \"name\": \"Calloway Cook\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/calloway-cook\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/calloway-cook\/\",\n \"jobTitle\": \"President\",\n \"knowsAbout\": \"entrepreneurship, dietary supplements, herbal supplements, eCommerce, medical research\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": \"S.I. Newhouse School of Public Communications at Syracuse University\"\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"editor\": {\n \"@type\": \"Person\",\n \"name\": \"Brian Moore\",\n \"honorificSuffix\": [\n \"M.D.\",\n \"F.A.A.D\"\n ],\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/brian-moore\",\n \"sameAs\": [\n \"https:\/\/www.linkedin.com\/in\/brian-moore-md-faad-2b1b77a2\/\",\n \"https:\/\/www.apexskin.com\/our-team\/dr-brian-moore-md\/\"\n ],\n \"jobTitle\": \"Dermatology Advisor\",\n \"knowsAbout\": \"dermatology, skincare, pigmented lesions, anti-aging, medical research, clinical trials, sunscreen, moisturizer, wrinkles, makeup, shampoo, soap\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"Columbia University\",\n \"University of Toledo\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"image\": {\n\"@type\": \"ImageObject\",\n\"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Jublia_Thumbnail.png?v=1706050064\",\n\"width\": \"3424\",\n\"height\": \"3424\"\n},\n\"citation\": [\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33539062\/\", \n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34303391\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34902110\/\",\n\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2014\/203567s000lbl.pdf\",\n\"https:\/\/www.drugs.com\/comments\/efinaconazole-topical\/jublia.html\",\n\"https:\/\/illuminatelabs.org\/blogs\/health\/liraglutide-review\",\n\"https:\/\/www.goodrx.com\/jublia\/what-is\",\n\"https:\/\/www.drugs.com\/availability\/generic-jublia.html\",\n\"https:\/\/illuminatelabs.org\/blogs\/health\/fungus-eliminator-review\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/pmid\/35631300\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17651080\/\"\n],\n\"mentions\": [{\n \"@type\": \"Thing\",\n \"name\": \"efinaconazole\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"toenail fungus\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"FDA\"\n },\n {\n \"@type\": \"Brand\",\n \"name\": \"Drugs.com\"\n },\n {\n \"@type\": \"Brand\",\n \"name\": \"GoodRx\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"American Academy of Dermatology\"\n }\n],\n\"datePublished\": \"2024-01-23\",\n\"copyrightHolder\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n},\n\"publisher\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\",\n \"url\": \"https:\/\/illuminatelabs.org\/\",\n \"description\": \"Illuminate Labs is the most transparent supplement company in the U.S., and is a leading publisher of research-based health information.\",\n \"knowsAbout\": \"supplements, science, nutrition, exercise, health, medication, pharmaceutical, wellness, diet, weight loss, medical research\",\n \"publishingPrinciples\": \"https:\/\/illuminatelabs.org\/pages\/editorial-guidelines\",\n \"memberOf\": [\n {\n \"@type\": \"Organization\",\n \"name\": \"U.S. Chamber of Commerce\",\n \"url\": \"https:\/\/www.uschamber.com\/\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Certified B Corp\",\n \"url\": \"https:\/\/www.bcorporation.net\/en-us\/\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Natural Products Association\",\n \"url\": \"https:\/\/www.npanational.org\/\"\n }\n ], \n \"logo\": {\n \"@type\": \"ImageObject\",\n \"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Illuminate_Labs_Favicon_48x48_7595c3cc-e27b-47b8-a4fe-edcc7ed9b29a.png?v=1666502785\", \n \"width\": 48,\n \"height\": 48\n},\n \"foundingDate\": \"2019-01-30\",\n \"sameAs\": [\n \"https:\/\/www.instagram.com\/illuminatelabs\",\n \"https:\/\/twitter.com\/illuminatelabs\",\n \"https:\/\/www.linkedin.com\/company\/illuminate-labs-supplements\",\n \"https:\/\/www.youtube.com\/channel\/UCpgSJAsIPb-fZ25djtTxBEA\"\n ]\n }\n}\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003cp\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Jublia_Review_Article_Header_Image_Optimized.png?v=1706037855\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003ci\u003e\u003cspan\u003eDisclaimer: None of the information in this article constitutes medical advice. All statements are merely the opinion of the writer(s). We recommend that patients follow their doctor’s guidance in regard to prescription antifungals.\u003c\/span\u003e\u003c\/i\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"dc\"\u003eJ\u003c\/span\u003eublia is a prescription cream used to treat toenail fungus. The generic name for this medication is \u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003eefinaconazole, and we'll use these terms interchangeably throughout this article because they refer to the same active drug ingredient.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBut is Jublia shown in research studies to cure toenail fungus? Does the medication cause any side effects? How do real Jublia patients rate and describe the effects of the treatment? And is the generic version equally effective?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIn this article we'll answer all of these questions and more, as we analyze clinical studies on Jublia to give our take on whether or not the medication is likely to be effective for the treatment of toenail fungus.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eWe'll document potential side effects, feature unsponsored patient reviews, and share our thoughts about whether or not the generic equivalent is a better purchase. \u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cstrong\u003eIs Jublia Proven to Work?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eJublia has been studied in clinical trials for its effects on toenail fungus.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eA \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33539062\/\"\u003eclinical trial\u003c\/a\u003e published in the \u003cem\u003eSkin Therapy Letter\u003c\/em\u003e found that \u003cstrong\u003eafter 24 months of use, over 74% of Jublia patients experienced a cure of their toenail fungus.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eJublia has also been clinically shown to be effective in children.\u003c\/p\u003e\n\u003cp\u003eAfter 52 weeks of use, 65% of children using Jublia once-daily were cured of their fungus in a 2021 \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34303391\/\"\u003eclinical trial\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003eA \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34902110\/\"\u003emedical review\u003c\/a\u003e on Jublia's antifungal efficacy, published in the \u003cem\u003eAmerican Journal of Clinical Dermatology\u003c\/em\u003e, concluded the following:\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\"Experts recommend [Jublia] 10% topical solution as the first line for mild-to-moderate onychomycosis, pediatric onychomycosis\u003c\/strong\u003e, those with liver or kidney disease, and as maintenance therapy to prevent relapse.\"\u003c\/p\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003eOnychomycosis is the medical term for nail fungus.\u003c\/p\u003e\n\u003cp\u003eBased on the available research, we consider Jublia likely to be effective for the treatment of toenail fungus, which is unsurprising given that the medication is approved by the FDA for this outcome.\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cstrong\u003eDoes Jublia Cause Side Effects?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eJublia has the potential to cause side effects in a minority of patients.\u003c\/p\u003e\n\u003cp\u003eThe drug's \u003ca href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2014\/203567s000lbl.pdf\"\u003eFDA label\u003c\/a\u003e documents \u003cstrong\u003ethe following side effects which occurred more than 1% of the time in clinical trials: ingrown toenails, dermatitis, vesicles, pain.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDermatitis is the medical term for swelling and irritation of the skin, and vesicles is the medical term for a blister filled with fluid.\u003c\/p\u003e\n\u003cp\u003eThe good news about Jublia's FDA label is that it's free of a \"black box\" warning, which is the most severe level of warning issued by the FDA, and indicates potentially life-threatening side effects.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThis suggests that Jublia is unlikely to cause serious side effects.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cstrong\u003ePatients Review Jublia\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eDrugs.com is a website that allows prescription medication patients to rate and review the drugs they're taking.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eWe cannot verify the accuracy or authenticity of any reviews on this site.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eJublia has been reviewed over 200 times \u003ca href=\"https:\/\/www.drugs.com\/comments\/efinaconazole-topical\/jublia.html\"\u003eon Drugs.com\u003c\/a\u003e at the time of publishing this article, and currently has an average review rating of 5.6 out of 10.\u003c\/p\u003e\n\u003cp\u003eThe top positive review comes from a user named \"Crystal\" who gives the medication a 10\/10 rating, and claims it was effective:\u003c\/p\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003e\u003cstrong\u003eI have been using Julia for a year. 4 of 5 affected toes are healed and look completely normal. My big toe is 90%.\u003c\/strong\u003e I was very consistent using the product daily.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe top negative review is written by a user named \"Infor...\" who gives the medication a 1\/10 rating, and claims it caused side effects:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003e\"\u003cmeta charset=\"utf-8\"\u003eSaw my family doctor and was prescribed Jublia and soon after the refill of my first bottle I developed a SEVERE reaction - blistering, swelling, rash, and redness.\u003c\/strong\u003e I didn’t link the problem to Jublia but did discontinue use.\"\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cstrong\u003eIs Jublia Generic a Better Choice?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eWe generally recommend that patients speak to their doctor about generic, rather than brand name, medications.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eThis is because generic medications have been clinically shown to be equivalently effective to brand-name medications in the aggregate, as we documented in our \u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/liraglutide-review\"\u003eliraglutide review\u003c\/a\u003e article, and can be significantly cheaper.\u003c\/p\u003e\n\u003cp\u003eHowever, \u003cstrong\u003eat the time of publishing this article, generic \u003cmeta charset=\"utf-8\"\u003e\u003c\/strong\u003e\u003cspan\u003e\u003cstrong\u003eefinaconazole is not available in the US\u003c\/strong\u003e \u003ca href=\"https:\/\/www.goodrx.com\/jublia\/what-is\"\u003eaccording to\u003c\/a\u003e GoodRx.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eGiven that a generic version of Jublia has been approved by the FDA \u003ca href=\"https:\/\/www.drugs.com\/availability\/generic-jublia.html\"\u003eaccording to\u003c\/a\u003e Drugs.com, a commercially available generic may emerge in the US soon.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eWe'd recommend that patients prescribed Jublia regularly check in with their doctor about the availability of a generic alternative.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cstrong\u003eHow Do You Prevent Toenail Fungus?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eAs we documented in our \u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/fungus-eliminator-review\"\u003eFungus Eliminator reviews\u003c\/a\u003e article, it's important to be proactive about preventing toenail fungus from re-ocurring after it's treated.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eA video from the American Academy of Dermatology is under 3 minutes long and includes six tips on preventing toenail fungus:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003ciframe title=\"YouTube video player\" src=\"https:\/\/www.youtube.com\/embed\/f1X5aPTzqTw\" height=\"315\" width=\"560\" allowfullscreen=\"\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" frameborder=\"0\"\u003e\u003c\/iframe\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eOur Clean Antifungal Picks\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/MCT_Oil_Image_8972b427-131a-4cb9-a18d-04b91b570afc.png?v=1700895076\"\u003e\u003c\/p\u003e\n\u003cp\u003eThere are some natural compounds with promising early research for treating fungus.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMedium chain triglyceride (MCT) oil\u003c\/strong\u003e was shown in a\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/pmid\/35631300\/\"\u003eclinical trial\u003c\/a\u003e\u003cspan\u003e \u003c\/span\u003epublished in the\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eNutrients\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003ejournal to be an effective oral antifungal:\u003c\/p\u003e\n\u003cp\u003e\"\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003eMCT holds promise as a therapeutic intervention for reducing fungal colonization without significant impact on the bacterial composition of the host gastrointestinal tract.\"\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003ca href=\"https:\/\/bulletproof.fdf2.net\/4eNQ4M\" rel=\"sponsored\"\u003eBulletproof MCT Oil\u003c\/a\u003e\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eis our top MCT oil pick, because its only ingredient is MCT oil derived from coconuts and it has zero additives. It currently retails for\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eunder $16\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCoconut oil\u003c\/strong\u003e may be an effective topical antifungal agent, as a 2007 \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17651080\/\"\u003emedical review\u003c\/a\u003e concluded that \"\u003cmeta charset=\"utf-8\"\u003eCoconut oil should be used in the treatment of fungal infections in view of emerging drug-resistant Candida species.\"\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003e\u003ca rel=\"sponsored\" href=\"https:\/\/amzn.to\/3jObsS9\"\u003eDr. Bronner's Organic Coconut Oil\u003c\/a\u003e\u003c\/strong\u003e is our top coconut oil pick, as it's packaged in glass, virgin (meaning it's not heat-treated), and has no questionable additive ingredients. The only ingredient is organic coconut oil.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eWe're not suggesting that either of these products should be used to treat any disease or health condition, or that they're as effective as any FDA-approved medication. Rather, we're sharing promising research on two natural compounds that individuals may wish to speak with their doctor or dermatologist about.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cstrong\u003eConclusion\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eJublia has been proven effective as a topical antifungal in multiple clinical trials.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eEarly research on this medication is impressive: in some studies, Jublia cured toenail fungus in over 70% of trial participants.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eJublia may cause mild side effects in some patients, including redness and irritation. The drug does not appear to confer the risk of severe side effects.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eWhile generic Jublia has been approved by the FDA, we can't find evidence that a generic Jublia exists in the US market. We recommend that patients prescribed Jublia ask their doctor about the availability of a generic alternative.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIn this article we featured a video from a prominent healthcare association with tips on preventing toenail fungus, which may be useful for patients who successfully treat their toenail fungus with Jublia, and want to prevent it from re-occurring.\u003c\/span\u003e\u003c\/p\u003e","blog_id":49281925193,"author":"Calloway Cook","user_id":26601750601,"published_at":"2024-01-23T17:51:53-05:00","updated_at":"2024-01-23T17:52:55-05:00","summary_html":"We analyze clinical studies on Jublia to determine whether or not the cream is effective against toenail fungus. We discuss the potential for side effects, feature patient reviews and share our thoughts on whether the generic alternative is a better choice.","template_suffix":"","handle":"jublia-review","tags":"_related:athlete's-foot"}

Jublia Review: Does Prescription Antifungal Cream Work?

Jublia Review: Does Prescription Antifungal Cream Work?


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Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.

Disclaimer: None of the information in this article constitutes medical advice. All statements are merely the opinion of the writer(s). We recommend that patients follow their doctor’s guidance in regard to prescription antifungals.

Jublia is a prescription cream used to treat toenail fungus. The generic name for this medication is efinaconazole, and we'll use these terms interchangeably throughout this article because they refer to the same active drug ingredient.

But is Jublia shown in research studies to cure toenail fungus? Does the medication cause any side effects? How do real Jublia patients rate and describe the effects of the treatment? And is the generic version equally effective?

In this article we'll answer all of these questions and more, as we analyze clinical studies on Jublia to give our take on whether or not the medication is likely to be effective for the treatment of toenail fungus.

We'll document potential side effects, feature unsponsored patient reviews, and share our thoughts about whether or not the generic equivalent is a better purchase. 

Is Jublia Proven to Work?

Jublia has been studied in clinical trials for its effects on toenail fungus.

A clinical trial published in the Skin Therapy Letter found that after 24 months of use, over 74% of Jublia patients experienced a cure of their toenail fungus.

Jublia has also been clinically shown to be effective in children.

After 52 weeks of use, 65% of children using Jublia once-daily were cured of their fungus in a 2021 clinical trial.

A medical review on Jublia's antifungal efficacy, published in the American Journal of Clinical Dermatology, concluded the following:

"Experts recommend [Jublia] 10% topical solution as the first line for mild-to-moderate onychomycosis, pediatric onychomycosis, those with liver or kidney disease, and as maintenance therapy to prevent relapse."

Onychomycosis is the medical term for nail fungus.

Based on the available research, we consider Jublia likely to be effective for the treatment of toenail fungus, which is unsurprising given that the medication is approved by the FDA for this outcome.

Does Jublia Cause Side Effects?

Jublia has the potential to cause side effects in a minority of patients.

The drug's FDA label documents the following side effects which occurred more than 1% of the time in clinical trials: ingrown toenails, dermatitis, vesicles, pain.

Dermatitis is the medical term for swelling and irritation of the skin, and vesicles is the medical term for a blister filled with fluid.

The good news about Jublia's FDA label is that it's free of a "black box" warning, which is the most severe level of warning issued by the FDA, and indicates potentially life-threatening side effects.

This suggests that Jublia is unlikely to cause serious side effects.

Patients Review Jublia

Drugs.com is a website that allows prescription medication patients to rate and review the drugs they're taking.

We cannot verify the accuracy or authenticity of any reviews on this site.

Jublia has been reviewed over 200 times on Drugs.com at the time of publishing this article, and currently has an average review rating of 5.6 out of 10.

The top positive review comes from a user named "Crystal" who gives the medication a 10/10 rating, and claims it was effective:

I have been using Julia for a year. 4 of 5 affected toes are healed and look completely normal. My big toe is 90%. I was very consistent using the product daily.

The top negative review is written by a user named "Infor..." who gives the medication a 1/10 rating, and claims it caused side effects:

"Saw my family doctor and was prescribed Jublia and soon after the refill of my first bottle I developed a SEVERE reaction - blistering, swelling, rash, and redness. I didn’t link the problem to Jublia but did discontinue use."

Is Jublia Generic a Better Choice?

We generally recommend that patients speak to their doctor about generic, rather than brand name, medications.

This is because generic medications have been clinically shown to be equivalently effective to brand-name medications in the aggregate, as we documented in our liraglutide review article, and can be significantly cheaper.

However, at the time of publishing this article, generic efinaconazole is not available in the US according to GoodRx.

Given that a generic version of Jublia has been approved by the FDA according to Drugs.com, a commercially available generic may emerge in the US soon.

We'd recommend that patients prescribed Jublia regularly check in with their doctor about the availability of a generic alternative.

How Do You Prevent Toenail Fungus?

As we documented in our Fungus Eliminator reviews article, it's important to be proactive about preventing toenail fungus from re-ocurring after it's treated.

A video from the American Academy of Dermatology is under 3 minutes long and includes six tips on preventing toenail fungus:

Our Clean Antifungal Picks

There are some natural compounds with promising early research for treating fungus.

Medium chain triglyceride (MCT) oil was shown in a clinical trial published in the Nutrients journal to be an effective oral antifungal:

"MCT holds promise as a therapeutic intervention for reducing fungal colonization without significant impact on the bacterial composition of the host gastrointestinal tract."

Bulletproof MCT Oil is our top MCT oil pick, because its only ingredient is MCT oil derived from coconuts and it has zero additives. It currently retails for under $16.

Coconut oil may be an effective topical antifungal agent, as a 2007 medical review concluded that "Coconut oil should be used in the treatment of fungal infections in view of emerging drug-resistant Candida species."

Dr. Bronner's Organic Coconut Oil is our top coconut oil pick, as it's packaged in glass, virgin (meaning it's not heat-treated), and has no questionable additive ingredients. The only ingredient is organic coconut oil.

We're not suggesting that either of these products should be used to treat any disease or health condition, or that they're as effective as any FDA-approved medication. Rather, we're sharing promising research on two natural compounds that individuals may wish to speak with their doctor or dermatologist about.

Stay up-to-date on our research reviews

Conclusion

Jublia has been proven effective as a topical antifungal in multiple clinical trials.

Early research on this medication is impressive: in some studies, Jublia cured toenail fungus in over 70% of trial participants.

Jublia may cause mild side effects in some patients, including redness and irritation. The drug does not appear to confer the risk of severe side effects.

While generic Jublia has been approved by the FDA, we can't find evidence that a generic Jublia exists in the US market. We recommend that patients prescribed Jublia ask their doctor about the availability of a generic alternative.

In this article we featured a video from a prominent healthcare association with tips on preventing toenail fungus, which may be useful for patients who successfully treat their toenail fungus with Jublia, and want to prevent it from re-occurring.