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{"id":556027183177,"title":"Saxenda Review: Are Weight Loss Injections Safe?","created_at":"2021-12-03T16:28:53-05:00","body_html":"\u003cscript type=\"application\/ld+json\"\u003e\/\/ \u003c![CDATA[\n{\n \"@context\": \"https:\/\/schema.org\",\n \"@type\": \"Article\",\n \"headline\": \"Saxenda Review: Are Weight Loss Injections Safe?\",\n \"keywords\": \"saxenda, saxenda reviews, saxenda review, saxenda side effects, saxenda weight loss, saxenda dose, saxenda weight loss reviews, what is saxenda\",\n \"description\": \"Our MD reviews the medical research on Saxenda, as well as its side effects, to determine whether we recommend it as a safe and effective weight loss treatment, or whether there are alternative options we recommend instead.\",\n \"url\": \"https:\/\/illuminatelabs.org\/blogs\/health\/saxenda-review\",\n\"author\": {\n \"@type\": \"Person\",\n \"name\": \"Taylor Graber MD\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/taylor-graber\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/taylor-j-graber-md-81351642\/\",\n \"jobTitle\": \"Content Partner\",\n \"knowsAbout\": \"medicine, health, anesthesiology, iv therapy, science, drugs, pharmaceutical, medical research, scientific research, medical journals, entrepreneurship, healthcare, orthopedic surgery, biomedical engineering\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"University of California San Diego\",\n \"Arizona University\",\n \"University of Arizona College of Medicine\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"contributor\": {\n \"@type\": \"Person\",\n \"name\": \"Calloway Cook\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/calloway-cook\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/calloway-cook\/\",\n \"jobTitle\": \"President\",\n \"knowsAbout\": \"entrepreneurship, dietary supplements, herbal supplements, eCommerce, medical research\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": \"S.I. Newhouse School of Public Communications at Syracuse University\"\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"editor\": {\n \"@type\": \"Person\",\n \"name\": \"DJ Mazzoni\",\n \"honorificSuffix\": [\n \"M.S.\",\n \"R.D.\",\n \"C.D.N.\",\n \"C.S.C.S.\"\n ],\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/dj-mazzoni\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/dj-mazzoni-rd-cdn-cscs-00a33038\/\",\n \"jobTitle\": \"Medical Reviewer\",\n \"knowsAbout\": \"exercise, drugs, pharmaceutical, health, workout, strength and conditioning, nutrition, dietetics, medicine, medical research, scientific research, scientific method, healthcare, patient care, wellness\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"State University of New York College Oswego\",\n \"D’Youville College\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"image\": {\n\"@type\": \"ImageObject\",\n\"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Saxenda_Thumbnail.jpg?v=1642311865\",\n\"width\": \"4000\",\n\"height\": \"4000\"\n},\n\"citation\": [\n\"https:\/\/illuminatelabs.org\/blogs\/health\/phentermine-review\", \n\"https:\/\/illuminatelabs.org\/blogs\/health\/contrave-review\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5358074\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19853906\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21844879\/\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8017323\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19335713\/\",\n\"https:\/\/illuminatelabs.org\/blogs\/health\/colon-broom-review\",\n\"https:\/\/illuminatelabs.org\/blogs\/health\/plenity-review\"\n],\n\"mentions\": [{\n \"@type\": \"Thing\",\n \"name\": \"liraglutide\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"side effects\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"dietary fiber\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"Plenity\"\n }\n],\n\"datePublished\": \"2021-12-15\",\n\"copyrightHolder\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n},\n\"publisher\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\",\n \"url\": \"https:\/\/illuminatelabs.org\/\",\n \"description\": \"Illuminate Labs is the most transparent supplement company in the U.S., and is a leading publisher of research-based health information.\",\n \"knowsAbout\": \"supplements, science, nutrition, exercise, health, medication, pharmaceutical, wellness, diet, weight loss, medical research\",\n \"publishingPrinciples\": \"https:\/\/illuminatelabs.org\/pages\/editorial-guidelines\",\n \"logo\": {\n \"@type\": \"ImageObject\",\n \"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Illuminate_Labs_Logo.png?v=1641249064\", \n \"width\": 150,\n \"height\": 150\n},\n \"foundingDate\": \"2019-01-30\",\n \"Address\": {\n \"@type\": \"PostalAddress\",\n \"streetAddress\": \"50 Union Street, Unit 9\",\n \"addressLocality\": \"Northampton\",\n \"addressRegion\": \"Massachusetts\",\n \"postalCode\": \"01060\",\n \"addressCountry\": \"US\"\n},\n \"sameAs\": [\n \"https:\/\/www.instagram.com\/illuminatelabs\",\n \"https:\/\/twitter.com\/illuminatelabs\",\n \"https:\/\/www.linkedin.com\/company\/illuminate-labs-supplements\",\n \"https:\/\/www.youtube.com\/channel\/UCpgSJAsIPb-fZ25djtTxBEA\"\n ]\n }\n}\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003e\u003cem\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/em\u003e\u003ci\u003e\u003cspan\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Saxenda_Review_Article_Header_Image_Optimized.png?v=1638567382\" alt=\"\"\u003e\u003c\/span\u003e\u003c\/i\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003e\u003cspan\u003eDisclaimer: None of the information in this article constitutes medical advice, and is just the opinion of the writer(s). We recommend that patients follow their doctor’s guidance in regards to prescription medication.\u003c\/span\u003e\u003c\/i\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cspan class=\"dc\"\u003eS\u003c\/span\u003eaxenda is one of the leading weight loss prescription medications. Interestingly, it’s an injectable medication unlike the standard pill format that was present in the \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/phentermine-review\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ePhentermine\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e and \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/contrave-review\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eContrave\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e weight loss medications that we previously reviewed.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn this article we’ll review the medical research on Saxenda to determine whether we recommend it as a safe and effective weight loss treatment, or whether there are alternative options we recommend instead.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eHow Does It Work?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eSaxenda’s active ingredient is a chemical compound called liraglutide, which stimulates insulin secretion in response to glucose. \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5358074\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eMedical research\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e has shown that this compound can cause weight loss in two ways: delayed gastric emptying and appetite suppression.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eDelayed gastric emptying means food stays in the stomach longer than usual, which keeps a patient full for longer. Appetite suppression is probably caused by this effect.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eBecause liraglutide stays in the body for a relatively long time (it has a half-life of 13 hours), Saxenda only needs to be used once daily in most cases.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eIs Saxenda Effective For Weight Loss?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eSaxenda’s dose of 3 milligrams (mg) of daily liraglutide has been studied in various medical trials for weight loss. One \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19853906\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e found that the dose in Saxenda was more effective for weight loss than both placebo and another popular weight loss medication called orlistat. Participants taking the same dosage as in Saxenda lost an average of 7.2 kilograms (kg) over the 20 week trial, which is equivalent to 15.9 pounds (Ibs).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOne interesting note about the above study is that participants at the Saxenda dosage also experienced a statistically significant decrease in blood pressure, and also a reduced prevalence of prediabetes.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAnother \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21844879\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e on liraglutide found that subjects using the dosage contained in Saxenda lost an average of 5.8 kg (12.8 lbs) more than placebo, and 3.6 kg (7.9 lbs) more than another leading weight loss drug. Similar to the previous study, there were secondary benefits outside of weight loss seen in the liraglutide group, including favorable blood pressure and cholesterol changes.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThere are other studies on Saxenda, but we can conclude that it’s effective for weight loss based on the medical research reviewed. Generally pharmaceutical medications have significant research backing their effectiveness, compared with supplements, even though they may have more concerning side effect profiles in some cases.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eSaxenda Side Effects\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe main side effects shown in medical research for Saxenda were gastrointestinal. This is unsurprising given how it works: delaying gastric emptying may cause nausea, diarrhea, constipation and vomiting as they list in the side effects section of their website.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003ePatients taking Saxenda also had a higher pulse rate than placebo.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe more concerning side effect in our opinion is the potentially increased risk of cancer, which Saxenda lists on their website. A \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8017323\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e on the side effects of liraglutide for weight loss concluded that “liraglutide may be associated with an increased risk of thyroid, pancreatic, and early breast cancer”.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIt appears that most of the research on cancer as a side effect of liraglutide has been at lower doses than that in Saxenda, so we look forward to more research emerging on the safety and cancer risk of 3 mg liraglutide (the dose used in Saxenda.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eBetter Natural Alternatives\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWhile Saxenda is shown to be effective for weight loss in the medical research reviewed, we believe that there are some natural alternatives which may provide superior weight loss results with a better side effect profile.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOne of the most well-studied lifestyle modifications for improved weight loss is a dietary change to significantly increase fiber intake. \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19335713\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eMedical research shows\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e that dietary fiber supplementation in obese individuals significantly enhances weight loss, and it does so in a dose-dependent fashion. This means that the more fiber consumed, to a limit, the most weight lost on average.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe reason this works is because fiber takes up space in the stomach and increases the sense of fullness without increasing calories. Fiber is indigestible plant matter. If you’ve ever wondered why you can feel more full after eating a healthy meal like a large salad with chicken and beans compared with the same amount of calories from processed food like chips, the reason is fiber.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eSome great sources of dietary fiber are beans, fruits and vegetables, nuts and seeds and dark chocolate.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eFor consumers who prefer dietary supplements, psyllium husk fiber is a powder that can be purchased relatively cheap and added to water or coffee or smoothies. It’s the active ingredient in expensive fiber supplements like \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/colon-broom-review\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eColon Broom\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e, but we recommend purchasing the plain powder instead of a branded version as it’s cheaper.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eFor patients who prefer a pharmaceutical approach to weight loss, we recommend speaking with your doctor about Plenity \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/plenity-review\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ewhich we also reviewed\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e. While we don’t necessarily recommend Plenity generally, we would recommend it over Saxenda because we believe it has a more favorable side effect profile.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eConclusion\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eSaxenda is a weight loss medication which is more effective than popular weight loss drug orlistat based on medical research. It appears to have secondary benefits like reduced blood pressure and improved lipid profile.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe don’t recommend Saxenda due to the potential side effects, and we believe lifestyle modifications like increased fiber intake are a better option for weight loss. However we do recommend that patients follow their doctor’s recommendation in regards to all prescription medication. Our comments are general in nature.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn the context of pharma weight loss drugs, we believe that Plenity is a better option, but we may change our opinion of that if more research emerges establishing the safety and investigating the carcinogenic effects of Saxenda’s dosage.\u003c\/span\u003e\u003c\/p\u003e","blog_id":49281925193,"author":"Calloway Cook","user_id":26601750601,"published_at":"2021-12-15T00:30:01-05:00","updated_at":"2022-01-16T00:48:02-05:00","summary_html":"\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003e\u003cspan\u003eWe review the medical research on weight loss medication Saxenda to determine whether we recommend it as a safe and effective treatment, or whether there are alternative options we recommend instead.\u003c\/span\u003e\u003c\/p\u003e","template_suffix":"","handle":"saxenda-review","tags":"_related:weight-loss"}

Saxenda Review: Are Weight Loss Injections Safe?

Saxenda Review: Are Weight Loss Injections Safe?


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Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.
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Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.


Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.

Disclaimer: None of the information in this article constitutes medical advice, and is just the opinion of the writer(s). We recommend that patients follow their doctor’s guidance in regards to prescription medication.

Saxenda is one of the leading weight loss prescription medications. Interestingly, it’s an injectable medication unlike the standard pill format that was present in the Phentermine and Contrave weight loss medications that we previously reviewed.

In this article we’ll review the medical research on Saxenda to determine whether we recommend it as a safe and effective weight loss treatment, or whether there are alternative options we recommend instead.

How Does It Work?

Saxenda’s active ingredient is a chemical compound called liraglutide, which stimulates insulin secretion in response to glucose. Medical research has shown that this compound can cause weight loss in two ways: delayed gastric emptying and appetite suppression.

Delayed gastric emptying means food stays in the stomach longer than usual, which keeps a patient full for longer. Appetite suppression is probably caused by this effect.

Because liraglutide stays in the body for a relatively long time (it has a half-life of 13 hours), Saxenda only needs to be used once daily in most cases.

Is Saxenda Effective For Weight Loss?

Saxenda’s dose of 3 milligrams (mg) of daily liraglutide has been studied in various medical trials for weight loss. One medical trial found that the dose in Saxenda was more effective for weight loss than both placebo and another popular weight loss medication called orlistat. Participants taking the same dosage as in Saxenda lost an average of 7.2 kilograms (kg) over the 20 week trial, which is equivalent to 15.9 pounds (Ibs).

One interesting note about the above study is that participants at the Saxenda dosage also experienced a statistically significant decrease in blood pressure, and also a reduced prevalence of prediabetes.

Another clinical trial on liraglutide found that subjects using the dosage contained in Saxenda lost an average of 5.8 kg (12.8 lbs) more than placebo, and 3.6 kg (7.9 lbs) more than another leading weight loss drug. Similar to the previous study, there were secondary benefits outside of weight loss seen in the liraglutide group, including favorable blood pressure and cholesterol changes.

There are other studies on Saxenda, but we can conclude that it’s effective for weight loss based on the medical research reviewed. Generally pharmaceutical medications have significant research backing their effectiveness, compared with supplements, even though they may have more concerning side effect profiles in some cases.

Saxenda Side Effects

The main side effects shown in medical research for Saxenda were gastrointestinal. This is unsurprising given how it works: delaying gastric emptying may cause nausea, diarrhea, constipation and vomiting as they list in the side effects section of their website.

Patients taking Saxenda also had a higher pulse rate than placebo.

The more concerning side effect in our opinion is the potentially increased risk of cancer, which Saxenda lists on their website. A medical review on the side effects of liraglutide for weight loss concluded that “liraglutide may be associated with an increased risk of thyroid, pancreatic, and early breast cancer”.

It appears that most of the research on cancer as a side effect of liraglutide has been at lower doses than that in Saxenda, so we look forward to more research emerging on the safety and cancer risk of 3 mg liraglutide (the dose used in Saxenda.

Better Natural Alternatives

While Saxenda is shown to be effective for weight loss in the medical research reviewed, we believe that there are some natural alternatives which may provide superior weight loss results with a better side effect profile.

One of the most well-studied lifestyle modifications for improved weight loss is a dietary change to significantly increase fiber intake. Medical research shows that dietary fiber supplementation in obese individuals significantly enhances weight loss, and it does so in a dose-dependent fashion. This means that the more fiber consumed, to a limit, the most weight lost on average.

The reason this works is because fiber takes up space in the stomach and increases the sense of fullness without increasing calories. Fiber is indigestible plant matter. If you’ve ever wondered why you can feel more full after eating a healthy meal like a large salad with chicken and beans compared with the same amount of calories from processed food like chips, the reason is fiber.

Some great sources of dietary fiber are beans, fruits and vegetables, nuts and seeds and dark chocolate.

For consumers who prefer dietary supplements, psyllium husk fiber is a powder that can be purchased relatively cheap and added to water or coffee or smoothies. It’s the active ingredient in expensive fiber supplements like Colon Broom, but we recommend purchasing the plain powder instead of a branded version as it’s cheaper.

For patients who prefer a pharmaceutical approach to weight loss, we recommend speaking with your doctor about Plenity which we also reviewed. While we don’t necessarily recommend Plenity generally, we would recommend it over Saxenda because we believe it has a more favorable side effect profile.

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Conclusion

Saxenda is a weight loss medication which is more effective than popular weight loss drug orlistat based on medical research. It appears to have secondary benefits like reduced blood pressure and improved lipid profile.

We don’t recommend Saxenda due to the potential side effects, and we believe lifestyle modifications like increased fiber intake are a better option for weight loss. However we do recommend that patients follow their doctor’s recommendation in regards to all prescription medication. Our comments are general in nature.

In the context of pharma weight loss drugs, we believe that Plenity is a better option, but we may change our opinion of that if more research emerges establishing the safety and investigating the carcinogenic effects of Saxenda’s dosage.





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