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{"id":555985502281,"title":"Hydroxycut Review: Powerful or Dangerous Supplement?","created_at":"2021-11-22T23:30:33-05:00","body_html":"\u003cscript type=\"application\/ld+json\"\u003e\/\/ \u003c![CDATA[\n{\n \"@context\": \"https:\/\/schema.org\",\n \"@type\": \"Article\",\n \"headline\": \"Hydroxycut Review: Powerful or Dangerous Supplement?\",\n \"keywords\": \"hydroxycut, hydroxycut reviews, hydroxycut review, does hydroxycut work, hydroxycut gummies, hydroxycut side effects, is hydroxycut safe, hydroxycut gummies reviews, hydroxycut ingredients, what is hydroxycut\",\n \"description\": \"Our MD reviews the formulation of some of Hydroxycut’s most popular products based on medical research to determine if the supplements are safe and likely to be effective for weight loss. We also highlight some concerning side effects found in research studies.\",\n \"url\": \"https:\/\/illuminatelabs.org\/blogs\/health\/hydroxycut-review\",\n\"author\": {\n \"@type\": \"Person\",\n \"name\": \"Taylor Graber MD\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/taylor-graber\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/taylor-j-graber-md-81351642\/\",\n \"jobTitle\": \"Content Partner\",\n \"knowsAbout\": \"medicine, health, anesthesiology, iv therapy, science, drugs, pharmaceutical, medical research, scientific research, medical journals, entrepreneurship, healthcare, orthopedic surgery, biomedical engineering\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"University of California San Diego\",\n \"Arizona University\",\n \"University of Arizona College of Medicine\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"contributor\": {\n \"@type\": \"Person\",\n \"name\": \"Calloway Cook\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/calloway-cook\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/calloway-cook\/\",\n \"jobTitle\": \"President\",\n \"knowsAbout\": \"entrepreneurship, dietary supplements, herbal supplements, eCommerce, medical research\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": \"S.I. Newhouse School of Public Communications at Syracuse University\"\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"editor\": {\n \"@type\": \"Person\",\n \"name\": \"DJ Mazzoni\",\n \"honorificSuffix\": [\n \"M.S.\",\n \"R.D.\",\n \"C.D.N.\",\n \"C.S.C.S.\"\n ],\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/dj-mazzoni\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/dj-mazzoni-rd-cdn-cscs-00a33038\/\",\n \"jobTitle\": \"Medical Reviewer\",\n \"knowsAbout\": \"exercise, drugs, pharmaceutical, health, workout, strength and conditioning, nutrition, dietetics, medicine, medical research, scientific research, scientific method, healthcare, patient care, wellness\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"State University of New York College Oswego\",\n \"D’Youville College\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"image\": {\n\"@type\": \"ImageObject\",\n\"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Hydroxycut_Thumbnail.jpg?v=1642355712\",\n\"width\": \"2807\",\n\"height\": \"2807\"\n},\n\"citation\": [\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2773866\/\", \n\"https:\/\/www.fda.gov\/media\/76365\/download\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7057255\/\",\n\"https:\/\/illuminatelabs.org\/blogs\/health\/meticore-review\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2943088\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31398662\/\",\n\"https:\/\/illuminatelabs.org\/blogs\/health\/goli-review\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26376619\/\"\n],\n\"mentions\": [{\n \"@type\": \"Thing\",\n \"name\": \"hepatitis\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"weight loss\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"Hydroxycut side effects\"\n }\n],\n\"datePublished\": \"2021-12-09\",\n\"copyrightHolder\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n},\n\"publisher\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\",\n \"url\": \"https:\/\/illuminatelabs.org\/\",\n \"description\": \"Illuminate Labs is the most transparent supplement company in the U.S., and is a leading publisher of research-based health information.\",\n \"knowsAbout\": \"supplements, science, nutrition, exercise, health, medication, pharmaceutical, wellness, diet, weight loss, medical research\",\n \"publishingPrinciples\": \"https:\/\/illuminatelabs.org\/pages\/editorial-guidelines\",\n \"logo\": {\n \"@type\": \"ImageObject\",\n \"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Illuminate_Labs_Logo.png?v=1641249064\", \n \"width\": 150,\n \"height\": 150\n},\n \"foundingDate\": \"2019-01-30\",\n \"Address\": {\n \"@type\": \"PostalAddress\",\n \"streetAddress\": \"50 Union Street, Unit 9\",\n \"addressLocality\": \"Northampton\",\n \"addressRegion\": \"Massachusetts\",\n \"postalCode\": \"01060\",\n \"addressCountry\": \"US\"\n},\n \"sameAs\": [\n \"https:\/\/www.instagram.com\/illuminatelabs\",\n \"https:\/\/twitter.com\/illuminatelabs\",\n \"https:\/\/www.linkedin.com\/company\/illuminate-labs-supplements\",\n \"https:\/\/www.youtube.com\/channel\/UCpgSJAsIPb-fZ25djtTxBEA\"\n ]\n }\n}\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003e\u003cem\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/em\u003e \u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Hydroxycut_Review_Article_Header_Image_Optimized.png?v=1637642635\" alt=\"\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cspan class=\"dc\"\u003eH\u003c\/span\u003eydroxycut is one of the most popular weight loss supplements in the U.S., selling over 100 million bottles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn this article we’ll review the formulation of some of Hydroxycut’s most popular products based on medical research to determine if it’s safe and likely to be effective for weight loss. We’ll also highlight some concerning side effects found in research studies.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eLiver Toxicity Reports\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThere is a concerning amount of research on acute liver injury associated with Hydroxycut use. A \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2773866\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e from 2008 highlighted two case reports of patients who developed hepatitis shortly after taking Hydroxycut. Hepatitis is a serious medical condition where the liver becomes inflamed, and can lead to long-term consequences if not treated rapidly.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe review couldn’t definitively conclude that the hepatitis was caused by Hydroxycut, because the patients could have just happened to get sick right after taking it, but we find that to be unlikely.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe Food and Drug Administration (FDA) which regulates supplements in the U.S. \u003c\/span\u003e\u003ca href=\"https:\/\/www.fda.gov\/media\/76365\/download\"\u003e\u003cspan style=\"font-weight: 400;\"\u003epublished\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e a Health Hazard Evaluation of the supplement, concluding that “it is very likely that exposure to Hydroxycut can cause idiosyncratic hepatotoxicity”. In layman’s terms, that means that the supplement can harm the liver.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA more recent \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7057255\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ecase report\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e from a medical journal detailed a 22 year old woman who experienced acute liver injury due to Hydroxycut use. The patient was successfully treated and discharged, but the study authors noted the risks of Hydroxycut use, and even described the standard symptom duration of what they called “Hydroxycut-induced liver injury”, meaning there’s a medical standard for these side effects which is concerning.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eDoes Hydroxycut Work?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThere is no clinical evidence that Hydroxycut is effective for weight loss. That means there have been no studies on the supplement proving it works for weight loss.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe will review the formulation of their most popular product Pro Clinical Hydroxycut to determine if it’s likely to be effective based on the ingredients it contains.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Hydroxycut_Vitamin_Mineral_Blend_Optimized.png?v=1637642986\" alt=\"Hydroxycut vitamin and mineral blend\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe first section of the formulation, shown above, is just a \u003c\/span\u003e\u003cb\u003evitamin and mineral blend\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e. As we detailed in our \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/meticore-review\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eMeticore review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e of a separate weight loss supplement brand, there is no clinical proof that random blends of vitamins and minerals are effective for weight loss. Manufacturers usually add them without explanation to fill out their Supplement Facts label, which appears to be the case here.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Hydroxycut_Prop_Blend_Optimized.png?v=1637643085\" alt=\"Hydroxycut prop blend\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe rest of the formulation, shown above, is a proprietary (prop) blend totalling 604 milligrams (mg), with three main active ingredients: robusta coffee extract 200 mg, apple cider vinegar 100 mg, and 204 mg of a different type of coffee extract.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eRobusta coffee extract\u003c\/b\u003e \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2943088\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emay be effective\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e for weight loss based on medical research, but there isn’t enough research to conclude one way or another, as the linked review states. A \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31398662\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emore recent review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e concluded that it should be effective.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe haven’t seen any research suggesting that \u003c\/span\u003e\u003cb\u003eapple cider vinegar\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e at 100 mg is likely to aid in weight loss efforts. This is a very low dose, 5x lower than \u003c\/span\u003e\u003ca href=\"https:\/\/illuminatelabs.org\/blogs\/health\/goli-review\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eGoli gummies\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e which we already reviewed and concluded to be underdosed and ineffective.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e204 mg \u003c\/span\u003e\u003cb\u003ecoffee extract\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e may aid in weight loss efforts as we discussed in the previous section. We find it strange that Hydroxycut lists these two active ingredients separately on the label, when robusta coffee extract is just a specific type of coffee extract.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe remaining three ingredients in this prop blend are plum, baobab extract and cardamom. These ingredients only total 100 mg, or 33 mg per ingredient on average, which is a very low dose. We believe this dosage is so low as to make each of these ingredients totally worthless.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAs an example to illustrate our point, a medical study on baobab extract tested its effects on blood sugar response. They used a “low dose” of 18.5 grams (g). 18.5 g = 18,500 mg. This means there was over 500 times more baobab used in this “low dose” study than there likely is in Hydroxycut.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eUnethical supplement manufacturers will often add a very small amount of exotic ingredients to their formulations hidden in a prop blend, so that their Supplement Facts panel looks more impressive. That appears to be the case here.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe don’t believe that Hydroxycut is likely to work, because there is limited research on the effectiveness of one of its ingredients (coffee extract) for weight loss. All of the other ingredients appear to be significantly underdosed.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eHydroxycut Gummies Review\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Hydroxycut_Gummies_Optimized_f804146b-4344-4420-9675-1bc0ef0d7bac.png?v=1637643268\" alt=\"Hydroxycut Gummies Supplement Facts label\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eHydroxycut also sells a gummy product with similar claims to their Pro Clinical product which we just reviewed.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe bulk of this formulation is an even larger random blend of vitamins and minerals. Hydroxycut provides no information about why they chose these nutrients and why they chose the dosages, so we can assume this blend will be ineffective for weight loss.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe only active botanical ingredient in this product is the \u003c\/span\u003e\u003cb\u003erobusta coffee extract\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e at the same dosage as in Pro Clinical. This ingredient may be effective for weight loss, but there isn’t enough clinical data to definitively say so.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThis product also contains 5 g of added sugar, mostly in the form of corn syrup. We know that added sugar in excess is unhealthy and obesogenic \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26376619\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ebased on medical data\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e (it’s one of the few things essentially all doctors agree on), so we question why a weight loss product would contain added sugar.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOverall we find Hydroxycut gummies to be a poor formulation, and don't recommend the product. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe recommend that consumers curious about robusta coffee extract talk to their doctors about taking it in isolation, because it’s the only potentially effective ingredient in this formulation. Taking it with a random blend of vitamins and minerals and added sugars doesn’t add any clinical benefit.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eHydroxycut Side Effects\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOther than the rare but significant adverse effects on the liver that we outlined earlier in the article, Hydroxycut may cause side effects due to its stimulatory ingredients.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003ePro Clinical Hydroxycut contains 200 mg of caffeine. While this is a safe dose for healthy adults, it may be dangerous for patients with high blood pressure or cardiovascular issues. We find it unacceptable that Hydroxycut doesn’t contain a warning on their product page that users should speak with their doctor prior to taking the product.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe also ethically disagree with the page on their site titled “Is Hydroxycut Safe?” which concludes that the product is safe to use by healthy adults. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThis is untrue based on the liver toxicity reports. Several of the patients who experienced liver injury were previously healthy as detailed in the FDA report.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThis is incredibly deceptive and dangerous marketing. The company is certainly aware of these reports, and isn’t even mentioning the risk on a page dedicated to risk. This alone should make any health-conscious consumer steer far clear from Hydroxycut.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAlso, how can they definitively claim that their product is safe for healthy adults when it’s never been tested in a clinical setting for toxicity or long-term safety?\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eConclusion\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe believe that Hydroxycut supplements are not only likely to be ineffective, but are a health risk. Even if they changed their formulation after the FDA warning, one of the liver injury case studies we reviewed was from 2020.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMost patients will not be affected, but why take the risk of severe adverse side effects when there are so many other weight loss therapies which are conclusively safe?\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe recommend that consumers avoid all Hydroxycut products. We believe that the company has a disregard for patient safety based on their marketing materials.\u003c\/span\u003e\u003c\/p\u003e","blog_id":49281925193,"author":"Calloway Cook","user_id":26601750601,"published_at":"2021-12-09T12:00:00-05:00","updated_at":"2022-01-16T12:58:31-05:00","summary_html":"\u003cmeta charset=\"utf-8\"\u003e\n\u003cdiv class=\"Polaris-Card__Section_1b1h1\"\u003e\n\u003cdiv\u003e\n\u003cp class=\"Sd8DF\"\u003eWe review the formulation of some of Hydroxycut’s most popular products based on medical research to determine if the supplements are safe and likely to be effective for weight loss. We also highlight some concerning side effects found in research studies.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","template_suffix":"","handle":"hydroxycut-review","tags":"_related:weight-loss"}

Hydroxycut Review: Powerful or Dangerous Supplement?

Hydroxycut Review: Powerful or Dangerous Supplement?


| |
Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.
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Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.


Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.

 

Hydroxycut is one of the most popular weight loss supplements in the U.S., selling over 100 million bottles.

In this article we’ll review the formulation of some of Hydroxycut’s most popular products based on medical research to determine if it’s safe and likely to be effective for weight loss. We’ll also highlight some concerning side effects found in research studies.

Liver Toxicity Reports

There is a concerning amount of research on acute liver injury associated with Hydroxycut use. A medical review from 2008 highlighted two case reports of patients who developed hepatitis shortly after taking Hydroxycut. Hepatitis is a serious medical condition where the liver becomes inflamed, and can lead to long-term consequences if not treated rapidly.

The review couldn’t definitively conclude that the hepatitis was caused by Hydroxycut, because the patients could have just happened to get sick right after taking it, but we find that to be unlikely.

The Food and Drug Administration (FDA) which regulates supplements in the U.S. published a Health Hazard Evaluation of the supplement, concluding that “it is very likely that exposure to Hydroxycut can cause idiosyncratic hepatotoxicity”. In layman’s terms, that means that the supplement can harm the liver.

A more recent case report from a medical journal detailed a 22 year old woman who experienced acute liver injury due to Hydroxycut use. The patient was successfully treated and discharged, but the study authors noted the risks of Hydroxycut use, and even described the standard symptom duration of what they called “Hydroxycut-induced liver injury”, meaning there’s a medical standard for these side effects which is concerning.

Does Hydroxycut Work?

There is no clinical evidence that Hydroxycut is effective for weight loss. That means there have been no studies on the supplement proving it works for weight loss.

We will review the formulation of their most popular product Pro Clinical Hydroxycut to determine if it’s likely to be effective based on the ingredients it contains.

Hydroxycut vitamin and mineral blend

The first section of the formulation, shown above, is just a vitamin and mineral blend. As we detailed in our Meticore review of a separate weight loss supplement brand, there is no clinical proof that random blends of vitamins and minerals are effective for weight loss. Manufacturers usually add them without explanation to fill out their Supplement Facts label, which appears to be the case here.

Hydroxycut prop blend

The rest of the formulation, shown above, is a proprietary (prop) blend totalling 604 milligrams (mg), with three main active ingredients: robusta coffee extract 200 mg, apple cider vinegar 100 mg, and 204 mg of a different type of coffee extract.

Robusta coffee extract may be effective for weight loss based on medical research, but there isn’t enough research to conclude one way or another, as the linked review states. A more recent review concluded that it should be effective.

We haven’t seen any research suggesting that apple cider vinegar at 100 mg is likely to aid in weight loss efforts. This is a very low dose, 5x lower than Goli gummies which we already reviewed and concluded to be underdosed and ineffective.

204 mg coffee extract may aid in weight loss efforts as we discussed in the previous section. We find it strange that Hydroxycut lists these two active ingredients separately on the label, when robusta coffee extract is just a specific type of coffee extract.

The remaining three ingredients in this prop blend are plum, baobab extract and cardamom. These ingredients only total 100 mg, or 33 mg per ingredient on average, which is a very low dose. We believe this dosage is so low as to make each of these ingredients totally worthless.

As an example to illustrate our point, a medical study on baobab extract tested its effects on blood sugar response. They used a “low dose” of 18.5 grams (g). 18.5 g = 18,500 mg. This means there was over 500 times more baobab used in this “low dose” study than there likely is in Hydroxycut.

Unethical supplement manufacturers will often add a very small amount of exotic ingredients to their formulations hidden in a prop blend, so that their Supplement Facts panel looks more impressive. That appears to be the case here.

We don’t believe that Hydroxycut is likely to work, because there is limited research on the effectiveness of one of its ingredients (coffee extract) for weight loss. All of the other ingredients appear to be significantly underdosed.

Hydroxycut Gummies Review

Hydroxycut Gummies Supplement Facts label

Hydroxycut also sells a gummy product with similar claims to their Pro Clinical product which we just reviewed.

The bulk of this formulation is an even larger random blend of vitamins and minerals. Hydroxycut provides no information about why they chose these nutrients and why they chose the dosages, so we can assume this blend will be ineffective for weight loss.

The only active botanical ingredient in this product is the robusta coffee extract at the same dosage as in Pro Clinical. This ingredient may be effective for weight loss, but there isn’t enough clinical data to definitively say so.

This product also contains 5 g of added sugar, mostly in the form of corn syrup. We know that added sugar in excess is unhealthy and obesogenic based on medical data (it’s one of the few things essentially all doctors agree on), so we question why a weight loss product would contain added sugar.

Overall we find Hydroxycut gummies to be a poor formulation, and don't recommend the product. 

We recommend that consumers curious about robusta coffee extract talk to their doctors about taking it in isolation, because it’s the only potentially effective ingredient in this formulation. Taking it with a random blend of vitamins and minerals and added sugars doesn’t add any clinical benefit.

Hydroxycut Side Effects

Other than the rare but significant adverse effects on the liver that we outlined earlier in the article, Hydroxycut may cause side effects due to its stimulatory ingredients.

Pro Clinical Hydroxycut contains 200 mg of caffeine. While this is a safe dose for healthy adults, it may be dangerous for patients with high blood pressure or cardiovascular issues. We find it unacceptable that Hydroxycut doesn’t contain a warning on their product page that users should speak with their doctor prior to taking the product.

We also ethically disagree with the page on their site titled “Is Hydroxycut Safe?” which concludes that the product is safe to use by healthy adults. 

This is untrue based on the liver toxicity reports. Several of the patients who experienced liver injury were previously healthy as detailed in the FDA report.

This is incredibly deceptive and dangerous marketing. The company is certainly aware of these reports, and isn’t even mentioning the risk on a page dedicated to risk. This alone should make any health-conscious consumer steer far clear from Hydroxycut.

Also, how can they definitively claim that their product is safe for healthy adults when it’s never been tested in a clinical setting for toxicity or long-term safety?

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Conclusion

We believe that Hydroxycut supplements are not only likely to be ineffective, but are a health risk. Even if they changed their formulation after the FDA warning, one of the liver injury case studies we reviewed was from 2020.

Most patients will not be affected, but why take the risk of severe adverse side effects when there are so many other weight loss therapies which are conclusively safe?

We recommend that consumers avoid all Hydroxycut products. We believe that the company has a disregard for patient safety based on their marketing materials.





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