Vyvamind is a nootropic supplement used to improve focus, concentration and mental energy. The brand claims that “our research has been exhaustive” and that Vyvamind “is the only brain supplement on the market designed for performance.”
But does Vyvamind contain research-backed ingredients for improving cognition? Does it contain any questionable additives? Has the supplement been clinically tested? And how do real users rate and describe the effects of Vyvamind?
In this article we’ll answer all of these questions and more, as we analyze the ingredients in Vyvamind to give our take on whether or not the supplement is likely to improve cognition, and whether or not it's healthy.
We'll share our concerns about some of the clinical claims on the brand's website, and feature real Vyvamind customer reviews.
Key takeaways:
- Contains research-backed active ingredients & no harmful fillers
- We consider some active ingredients to be underdosed
- We do not currently recommend Vyvamind
Ingredient Analysis
The active ingredients in Vyvamind are shown below:

Caffeine is one of the most well-studied nootropic ingredients, and was shown in a medical review published in the Journal of Alzheimer’s Disease to improve focus, cognition and memory.
The 75 milligram (mg) dose in Vyvamind, equivalent to around 80% of one cup of coffee, is relatively low based on our review of medical research, but still in the effective range.
L-theanine is an amino acid that has synergistic effects with caffeine.
A 2008 clinical trial found that the combination of caffeine and l-theanine improved performance on cognitively demanding tasks.
Citicoline is clinically shown to improve memory in older adults, however as we discussed in our review of Vitaae, we cannot find any medical trials proving this ingredient effective at a dose lower than 500 mg.
The dose in Vyvamind is only 200 mg.
L-tyrosine is another amino acid shown to improve cognition in a 2015 clinical trial, but the dose used was 2,000 mg, or more than 600% of the dose in Vyvamind.
Vitamin B6 and vitamin B12 are the two remaining active ingredients, and we cannot find any clinical evidence that these two vitamins improve cognition in individuals without deficiencies in these vitamins.
The inactive ingredients in this formulation, shown below, should be safe and non-toxic:

Overall, we consider Vyvamind somewhat likely to support cognition and memory, although we consider many of its active ingredients to be underdosed.
For this reason, we do not currently recommend Vyvamind.
Real People Try Vyvamind
A YouTube creator named “Mr RAGE” who claims to have ADHD complains that Vyvamind is a waste of money:
A TikTok creator named Rika Shanay shared her experience using Vyvamind:
@rikashanay A quick review for Vyvamind. Neurostimulant + Focus aid supplement. Please do your own research! B6 & B12 included. #supplements #memory #vyvamind #focus #itsachickensalad #yallbettercomeuphereandgetoneofthese ♬ original sound - Rika Shanay
Questionable Clinical Claims
Update: the brand appears to have removed all of these clinical citations since our initial publication of this article, calling out this information.
We still believe this information is useful to preserve for potential consumers.
At the time of initially publishing this article, the Vyvamind website had a “Research and Formulation” section that cited clinical studies on the efficacy of the active ingredients in the supplement.
However, in some cases, the research cited used doses entirely different from that in Vyvamind.
As shown below, the Vyvamind website claimed that citicoline can increase brain energy by over 13%:
However, the clinical trial cited to back this claim used daily doses of 500 mg or 2,000 mg of citicoline, which is 250% and 1,000% higher than the dose per-serving in Vyvamind.
The Vyvamind website claimed that tyrosine can reduce reaction times and minimize stress:
However, the medical review cited to back this claim does not prove these effects at the dose in Vyvamind.
The Vyvamind website claimed that vitamins B6 and B12 can support brain health:
However, the clinical trial cited to back this claim only studied the effects of vitamin B6 supplementation (not vitamin B12 supplementation), and the daily dose used was 20 mg, or 800% of the amount in Vyvamind.
Does Vyvamind Cause Side Effects?
Vyvamind does not appear to be clinically tested, so it’s challenging to say for certain whether or not the supplement will cause side effects.
However, we can make an educated guess based on its active ingredients.
We do not consider Vyvamind likely to cause side effects in otherwise healthy adults.
All of its active ingredients are well-studied, and none are included at a dangerously high dose in our opinion.
Even caffeine, which is a stimulant, is included at a dose less than the equivalent of one cup of coffee, so it should be acceptable for even caffeine-sensitive individuals.
The l-theanine has a calming effect which should balance caffeine’s stimulatory effects.
The brand’s website currently states that taking the recommended dose is unlikely to cause side effects, while taking more than the recommended dose “drastically increases the risks of side effects.”
Our Clean Nootropic Picks
Illuminate Labs Ginkgo Biloba Extract is our top herbal nootropic pick.
A medical review published in the Psychopharmacology journal found that ginkgo biloba supplementation improved attention and cognitive performance in healthy, young adults.
Mind Lab Pro by Performance Lab is our top multi-ingredient nootropic pick.
This is the first Illuminate Labs Certified supplement, and has been shown to be effective for short-term cognitive improvements in two clinical trials published in peer-reviewed journals.
Where to Buy Vyvamind
At the time of publishing this article, Vyvamind only appears to be for sale on the manufacturer’s official website, which can be accessed here (we do not endorse this product nor are we affiliated with this brand).
Vyvamind does not appear to be sold on large third-party internet retailers like Amazon or Walmart, and purchasing directly from the brand may reduce the risk of counterfeit products.
There is no mention of authorized retailers or distributors that we could find on the Vyvamind website, so for consumers intent on purchasing this supplement, we recommend doing so from the brand directly.
Vyvamind Pros and Cons
Here are the pros and cons of Vyvamind in our opinion:
Pros:
- Several research-backed active ingredients
- Should support cognition
- Should support memory
- Safe active ingredients
- Unlikely to cause side effects
Cons:
- Brand makes questionable research claims
- Some active ingredients are underdosed in our opinion
- Expensive
- Doesn’t appear clinically tested