{"id":604516909362,"title":"Quviviq Review: Restful Sleep in a Pill?","created_at":"2022-12-15T16:16:01-05:00","body_html":"\u003cscript type=\"application\/ld+json\"\u003e\/\/ \u003c![CDATA[\n{\n \"@context\": \"https:\/\/schema.org\",\n \"@type\": \"Article\",\n \"headline\": \"Quviviq Review: Restful Sleep in a Pill?\",\n \"keywords\": \"quviviq, quviviq review, quviviq reviews, quviviq side effects, quviviq cost, quviviq vs ambien, sleep aid quviviq\",\n \"description\": \"Our research team reviews medical studies on Quviviq to determine if the drug is effective for insomnia. We compare its effectiveness to Ambien, document side effects of the drug, and share real, unsponsored patient reviews of Quviviq.\",\n \"url\": \"https:\/\/illuminatelabs.org\/blogs\/health\/quviviq-review\",\n\"author\": {\n \"@type\": \"Person\",\n \"name\": \"Calloway Cook\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/calloway-cook\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/calloway-cook\/\",\n \"jobTitle\": \"President\",\n \"knowsAbout\": \"entrepreneurship, dietary supplements, herbal supplements, eCommerce, medical research\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": \"S.I. Newhouse School of Public Communications at Syracuse University\"\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"creator\": {\n \"@type\": \"Person\",\n \"name\": \"Calloway Cook\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/calloway-cook\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/calloway-cook\/\",\n \"jobTitle\": \"President\",\n \"knowsAbout\": \"entrepreneurship, dietary supplements, herbal supplements, eCommerce, medical research\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": \"S.I. Newhouse School of Public Communications at Syracuse University\"\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"editor\": {\n \"@type\": \"Person\",\n \"name\": \"Auren Weinberg\",\n \"honorificSuffix\": \"M.D.\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/auren-weinberg\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/aurenweinberg\/\",\n \"jobTitle\": \"Medical Reviewer\",\n \"knowsAbout\": \"pharmaceutical medication, medicine, OTC drugs, medical research, clinical trials, generic drugs, branded drugs, dietary supplements, chemistry, health, wellness, healthcare\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"Haverford College\",\n \"University of Rochester School of Medicine and Dentistry\",\n \"Fox School of Business at Temple University\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"image\": {\n\"@type\": \"ImageObject\",\n\"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Quviviq_Thumbnail.png?v=1671139187\",\n\"width\": \"3000\",\n\"height\": \"3000\"\n},\n\"citation\": [\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36098753\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35065036\/\",\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9553778\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31953863\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34480579\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36098753\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32341187\/\",\n\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2022\/214985s000lbl.pdf\",\n\"https:\/\/www.goodrx.com\/quviviq\",\n\"https:\/\/www.quviviq.com\/savings\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31714321\/\",\n\"https:\/\/www.drugs.com\/comments\/daridorexant\/quviviq-for-insomnia.html\"\n],\n\"mentions\": [{\n \"@type\": \"Organization\",\n \"name\": \"FDA\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"daridorexant\"\n },\n {\n \"@type\": \"Brand\",\n \"name\": \"Christy Risinger, MD\"\n },\n {\n \"@type\": \"Brand\",\n \"name\": \"GoodRx\"\n },\n {\n \"@type\": \"Brand\",\n \"name\": \"Drugs.com\"\n }\n],\n\"datePublished\": \"2022-12-15\",\n\"copyrightHolder\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n},\n\"publisher\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\",\n \"url\": \"https:\/\/illuminatelabs.org\/\",\n \"description\": \"Illuminate Labs is the most transparent supplement company in the U.S., and is a leading publisher of research-based health information.\",\n \"knowsAbout\": \"supplements, science, nutrition, exercise, health, medication, pharmaceutical, wellness, diet, weight loss, medical research\",\n \"publishingPrinciples\": \"https:\/\/illuminatelabs.org\/pages\/editorial-guidelines\",\n \"memberOf\": [\n {\n \"@type\": \"Organization\",\n \"name\": \"U.S. Chamber of Commerce\",\n \"url\": \"https:\/\/www.uschamber.com\/\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Certified B Corp\",\n \"url\": \"https:\/\/www.bcorporation.net\/en-us\/\"\n },\n {\n \"@type\": \"Organization\",\n \"name\": \"Natural Products Association\",\n \"url\": \"https:\/\/www.npanational.org\/\"\n }\n ],\n \"logo\": {\n \"@type\": \"ImageObject\",\n \"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Illuminate_Labs_Favicon_48x48_7595c3cc-e27b-47b8-a4fe-edcc7ed9b29a.png?v=1666502785\", \n \"width\": 48,\n \"height\": 48\n},\n \"foundingDate\": \"2019-01-30\",\n \"sameAs\": [\n \"https:\/\/www.instagram.com\/illuminatelabs\",\n \"https:\/\/twitter.com\/illuminatelabs\",\n \"https:\/\/www.linkedin.com\/company\/illuminate-labs-supplements\",\n \"https:\/\/www.youtube.com\/channel\/UCpgSJAsIPb-fZ25djtTxBEA\"\n ]\n }\n}\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003cp\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Quviviq_Review_Article_Header_Image_Optimized.png?v=1671138847\" alt=\"\"\u003e\u003c\/span\u003e\u003c\/i\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eDisclaimer: None of the information in this article constitutes medical advice, and is just the opinion of the writer(s). We recommend that patients follow their doctor’s guidance in regard to insomnia and sleep medication.\u003c\/span\u003e\u003c\/i\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cspan class=\"dc\"\u003eQ\u003c\/span\u003euviviq is a prescription sleep medication that was approved by the FDA in January of 2022. The manufacturer claims that this drug can “help you fall asleep faster and stay asleep longer” and that by using it you may feel less tired during the day.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe generic version of this medication is called daridorexant, and we’ll use these terms interchangeably because they refer to the same active drug ingredient.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eBut is Quviviq actually shown in clinical trials to improve sleep quality and duration? And if so, by how much? Does the drug cause side effects? And how do real users rate and describe the effects of Quviviq.\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn this article we’ll answer all of these questions and more as we review medical research on Quviviq to determine if the medication is likely to be effective for insomnia. We’ll document side effects of the drug, compare its efficacy to Ambien (another leading insomnia medication), and share real, unsponsored user reviews of Quviviq.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eHow Effective is Quviviq?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eQuviviq has been studied in various clinical trials for its ability to treat insomnia.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36098753\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in the \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eEuropean Journal of Clinical Pharmacology\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e analyzed data from clinical trials on Quviviq, and found that \u003c\/span\u003e\u003cb\u003ethe drug significantly reduced nighttime waking after sleep, significantly reduced time-to-sleep, and significantly improved overall sleep duration.\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA 2022 \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35065036\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e evaluated the effectiveness of Quviviq in patients with diagnosed insomnia. The medication was found effective, with patients on Quviviq taking 11.7 fewer minutes to fall asleep than patients taking placebo pills. Total sleep time was increased by around 10 minutes.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAnother \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9553778\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e compared the effects of Quviviq in older and younger adults with insomnia. The drug was found to be slightly more effective in older adults, with older patients waking less frequently.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe study authors suggested based on the data that older adults may require the higher dose of 50 milligrams (mg) to improve daytime functioning, while younger adults may see improvements in daytime functioning with the lower 25 mg dose.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOverall we will conclude that Quviviq is effective for treating insomina based on a review of medical research. But how does the drug’s effectiveness compare to Ambien? We’ll review in the next section.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eIs Quviviq More Effective Than Ambien?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAmbien is one of the most commonly-prescribed sleep medications, so insomnia patients are often curious about which drug is more effective. There have been comparative studies on the two drugs.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31953863\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in the \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eAnnals of Neurology\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e journal compared Quviviq and Ambien in patients with insomnia. \u003c\/span\u003e\u003cb\u003eAmbien was more effective than all doses of Quviviq for reducing time-to-sleep. Ambien was similarly effective to Quviviq in terms of daytime sleepiness and functioning.\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAmbien caused more patients to experience side effects (40%) than Quviviq (36.25%).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA 2022 \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34480579\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e compared the abuse potential of Quviviq and Ambien, and found that lower doses of Quviviq had lower addiction potential (due to lower scores of “drug-liking” by patients) than Ambien.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eBased on the available data we will conclude that Ambien may be slightly more effective than Quviviq for insomnia, but more research is needed to say so conclusively. Quviviq appears to have a slightly more favorable side effect profile than Ambien.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIt seems best that patients with mild-to-moderate insomnia should speak to their doctor about Quviviq, while patients with more severe insomnia may benefit from speaking to their doctor about Ambien.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eDoes Quviviq Cause Side Effects?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAs referenced in the previous section, Quviviq does cause side effects in some patients.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36098753\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emeta-study\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e on Quviviq reported \u003c\/span\u003e\u003cb\u003ethe most common side effects as cold symptoms and headache.\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32341187\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in the \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eNeurology\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e journal reported fatigue and walking disturbances as other common side effects.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eCompared to the side effect profile of some pharmaceutical drugs, these potential side effects are relatively mild. It’s also notable that Quviviq’s \u003c\/span\u003e\u003ca href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2022\/214985s000lbl.pdf\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eFDA label\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e is free of a “black box” warning which is required for drugs with life-threatening side effects.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eAre Sleeping Pills Unsafe?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA YouTube video published by a doctor named Christy Risinger, MD explains whether sleeping pills are dangerous, and shares some interesting information about negative health outcomes associated with sleeping pill use.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe video is unsponsored and has been viewed over 80,000 times: \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ciframe width=\"560\" height=\"315\" src=\"https:\/\/www.youtube.com\/embed\/dxZOS4nBUu0\" title=\"YouTube video player\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen=\"\"\u003e\u003c\/iframe\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eHow Much Does Quviviq Cost?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe price of Quviviq that any individual will pay will depend on their health insurance coverage.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAt the time of writing this article, GoodRx \u003c\/span\u003e\u003ca href=\"https:\/\/www.goodrx.com\/quviviq\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ereports\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e that the average retail price of Quviviq is \u003c\/span\u003e\u003cb\u003e$551.74\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e, so this is what uninsured patients can expect to pay.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe recommend that patients with health insurance contact their insurance provider to get a price estimate of Quviviq. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eQuviviq’s website also has a \u003c\/span\u003e\u003ca href=\"https:\/\/www.quviviq.com\/savings\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eSavings page\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e where patients can apply for a “QSavings Card” that can reduce the price to $0 for the first fill and $25 for subsequent fills. However, the website does not specify who qualifies for the reduced prices or for how long. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe typically recommend that patients speak with their doctor about the generic alternative to brand-name drugs, because generics are equally effective, on average, and can be significantly cheaper. However in the case of Quviviq, no generic version is currently available as the drug was only approved by the FDA in 2022.\u003c\/span\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eResearch-Backed Sleep Supplement\u003c\/b\u003e\u003c\/h2\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Is_Melatonin_Safe_Article_Header_Image_Optimized_a726a044-cb5a-4172-b2da-604d5181efd7.png?v=1662522659\" alt=\"\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe recommend \u003c\/span\u003e\u003ca rel=\"sponsored\" href=\"https:\/\/bulletproof.fdf2.net\/a1XMvQ\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eBulletproof Sleep\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e to consumers seeking a natural, over-the-counter (OTC) sleep supplement.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIt contains an effective dose of melatonin (3 mg), and also passionflower extract which has been shown in a \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31714321\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eclinical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e to increase total sleep time and decrease wakefulness. Most importantly, the supplement contains no questionable additive ingredients like flavoring agents.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe’re not suggesting that Bulletproof Sleep is as effective as Quviviq, or that this supplement should be used to treat any medical condition. We’re just sharing this option for consumers that may be averse to using prescription medication to improve sleep.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eInterested consumers can check out Bulletproof Sleep \u003c\/span\u003e\u003ca rel=\"sponsored\" href=\"https:\/\/bulletproof.fdf2.net\/a1XMvQ\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eat this link\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e to the product page on the brand’s official website.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eReal Patient Reviews of Quviviq\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eQuviviq has been reviewed over 30 times \u003c\/span\u003e\u003ca href=\"https:\/\/www.drugs.com\/comments\/daridorexant\/quviviq-for-insomnia.html\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eon Drugs.com\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e, which is a website that allows prescription medication users to rate the drug(s) they’re taking and publish personal reviews.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe medication has an average review rating of 2.9 out of 10 which is unimpressive.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe top positive review comes from a user named “EBS” who gives the drug an 8\/10 rating and claims it has been more effective than a different prescription insomnia medication:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e“After spending the past two and a half years sleeping in hell on Belsomra 10-20mg\/night, I have finally found a caring physician willing to Rx me Quviviq 25-50mg\/night. There are still some negative side effects, especially next-day anxiety…\u003c\/span\u003e\u003cb\u003eAt least there is much less anxiety and next day sleepiness with this than with Belsomra; it has a shorter half life.\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e”\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe top negative review is written by a user named “Deb72” who claims Quviviq caused side effects:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e“This was horrible, if I slept it was short periods with vivid nightmares waking me up, body hurts legs restless. Sleepy all the next day worse than if I'm awake all night with no meds, this drug was overly advertised. I just spent 7 days with no sleep as I was told it would get better which it never did nightmare”.\u003c\/b\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eConclusion\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eQuviviq is effective for the treatment of insomnia, and the drug is clinically proven to reduce time-to-sleep, increase overall sleep time, and improve daytime wakefulness scores.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eQuviviq does cause side effects in some patients including headache and cold symptoms, but the drug does not appear to cause severe or life-threatening side effects.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAfter reviewing comparative studies between Ambien and Quviviq, it appears that Ambien may be slightly more effective and Quviviq may have a slightly more favorable side effect profile.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThere is not a generic alternative for \u003c\/span\u003e \u003cspan style=\"font-weight: 400;\"\u003eQuviviq currently available on the market, so patients should speak with their health insurance provider to determine the cost of this drug, which will vary based on insurance coverage.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eSome medical research suggests that use of prescription sleep medications is associated with negative health outcomes. This may be an association not a causation (because people with insomnia are less healthy in general than people without). It may be worthwhile for patients with mild insomnia to speak with their doctor about lifestyle changes or natural, OTC treatments prior to considering prescription sleep drugs.\u003c\/span\u003e\u003c\/p\u003e","blog_id":49281925193,"author":"Calloway Cook","user_id":26601750601,"published_at":"2022-12-15T16:24:10-05:00","updated_at":"2022-12-18T16:19:59-05:00","summary_html":"We review medical studies on Quviviq to determine if the drug is effective for insomnia. We compare its effectiveness to Ambien, document side effects of the drug, and share real, unsponsored patient reviews of Quviviq.","template_suffix":"","handle":"quviviq-review","tags":"_related:sleep"}

Quviviq Review: Restful Sleep in a Pill?

Quviviq Review: Restful Sleep in a Pill?


| |
| |


Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.

Disclaimer: None of the information in this article constitutes medical advice, and is just the opinion of the writer(s). We recommend that patients follow their doctor’s guidance in regard to insomnia and sleep medication.

Quviviq is a prescription sleep medication that was approved by the FDA in January of 2022. The manufacturer claims that this drug can “help you fall asleep faster and stay asleep longer” and that by using it you may feel less tired during the day.

The generic version of this medication is called daridorexant, and we’ll use these terms interchangeably because they refer to the same active drug ingredient.

But is Quviviq actually shown in clinical trials to improve sleep quality and duration? And if so, by how much? Does the drug cause side effects? And how do real users rate and describe the effects of Quviviq.

In this article we’ll answer all of these questions and more as we review medical research on Quviviq to determine if the medication is likely to be effective for insomnia. We’ll document side effects of the drug, compare its efficacy to Ambien (another leading insomnia medication), and share real, unsponsored user reviews of Quviviq.

How Effective is Quviviq?

Quviviq has been studied in various clinical trials for its ability to treat insomnia.

A medical review published in the European Journal of Clinical Pharmacology analyzed data from clinical trials on Quviviq, and found that the drug significantly reduced nighttime waking after sleep, significantly reduced time-to-sleep, and significantly improved overall sleep duration.

A 2022 clinical trial evaluated the effectiveness of Quviviq in patients with diagnosed insomnia. The medication was found effective, with patients on Quviviq taking 11.7 fewer minutes to fall asleep than patients taking placebo pills. Total sleep time was increased by around 10 minutes.

Another clinical trial compared the effects of Quviviq in older and younger adults with insomnia. The drug was found to be slightly more effective in older adults, with older patients waking less frequently.

The study authors suggested based on the data that older adults may require the higher dose of 50 milligrams (mg) to improve daytime functioning, while younger adults may see improvements in daytime functioning with the lower 25 mg dose.

Overall we will conclude that Quviviq is effective for treating insomina based on a review of medical research. But how does the drug’s effectiveness compare to Ambien? We’ll review in the next section.

Is Quviviq More Effective Than Ambien?

Ambien is one of the most commonly-prescribed sleep medications, so insomnia patients are often curious about which drug is more effective. There have been comparative studies on the two drugs.

A clinical trial published in the Annals of Neurology journal compared Quviviq and Ambien in patients with insomnia. Ambien was more effective than all doses of Quviviq for reducing time-to-sleep. Ambien was similarly effective to Quviviq in terms of daytime sleepiness and functioning.

Ambien caused more patients to experience side effects (40%) than Quviviq (36.25%).

A 2022 clinical trial compared the abuse potential of Quviviq and Ambien, and found that lower doses of Quviviq had lower addiction potential (due to lower scores of “drug-liking” by patients) than Ambien.

Based on the available data we will conclude that Ambien may be slightly more effective than Quviviq for insomnia, but more research is needed to say so conclusively. Quviviq appears to have a slightly more favorable side effect profile than Ambien.

It seems best that patients with mild-to-moderate insomnia should speak to their doctor about Quviviq, while patients with more severe insomnia may benefit from speaking to their doctor about Ambien.

Does Quviviq Cause Side Effects?

As referenced in the previous section, Quviviq does cause side effects in some patients.

A meta-study on Quviviq reported the most common side effects as cold symptoms and headache.

A clinical trial published in the Neurology journal reported fatigue and walking disturbances as other common side effects.

Compared to the side effect profile of some pharmaceutical drugs, these potential side effects are relatively mild. It’s also notable that Quviviq’s FDA label is free of a “black box” warning which is required for drugs with life-threatening side effects.

Are Sleeping Pills Unsafe?

A YouTube video published by a doctor named Christy Risinger, MD explains whether sleeping pills are dangerous, and shares some interesting information about negative health outcomes associated with sleeping pill use.

The video is unsponsored and has been viewed over 80,000 times: 

How Much Does Quviviq Cost?

The price of Quviviq that any individual will pay will depend on their health insurance coverage.

At the time of writing this article, GoodRx reports that the average retail price of Quviviq is $551.74, so this is what uninsured patients can expect to pay.

We recommend that patients with health insurance contact their insurance provider to get a price estimate of Quviviq. 

Quviviq’s website also has a Savings page where patients can apply for a “QSavings Card” that can reduce the price to $0 for the first fill and $25 for subsequent fills. However, the website does not specify who qualifies for the reduced prices or for how long. 

We typically recommend that patients speak with their doctor about the generic alternative to brand-name drugs, because generics are equally effective, on average, and can be significantly cheaper. However in the case of Quviviq, no generic version is currently available as the drug was only approved by the FDA in 2022.

Research-Backed Sleep Supplement

We recommend Bulletproof Sleep to consumers seeking a natural, over-the-counter (OTC) sleep supplement.

It contains an effective dose of melatonin (3 mg), and also passionflower extract which has been shown in a clinical trial to increase total sleep time and decrease wakefulness. Most importantly, the supplement contains no questionable additive ingredients like flavoring agents.

We’re not suggesting that Bulletproof Sleep is as effective as Quviviq, or that this supplement should be used to treat any medical condition. We’re just sharing this option for consumers that may be averse to using prescription medication to improve sleep.

Interested consumers can check out Bulletproof Sleep at this link to the product page on the brand’s official website.

Real Patient Reviews of Quviviq

Quviviq has been reviewed over 30 times on Drugs.com, which is a website that allows prescription medication users to rate the drug(s) they’re taking and publish personal reviews.

The medication has an average review rating of 2.9 out of 10 which is unimpressive.

The top positive review comes from a user named “EBS” who gives the drug an 8/10 rating and claims it has been more effective than a different prescription insomnia medication:

“After spending the past two and a half years sleeping in hell on Belsomra 10-20mg/night, I have finally found a caring physician willing to Rx me Quviviq 25-50mg/night. There are still some negative side effects, especially next-day anxiety…At least there is much less anxiety and next day sleepiness with this than with Belsomra; it has a shorter half life.

The top negative review is written by a user named “Deb72” who claims Quviviq caused side effects:

“This was horrible, if I slept it was short periods with vivid nightmares waking me up, body hurts legs restless. Sleepy all the next day worse than if I'm awake all night with no meds, this drug was overly advertised. I just spent 7 days with no sleep as I was told it would get better which it never did nightmare”.

Get our most popular articles straight to your inbox
Stay up-to-date on our research reviews

Conclusion

Quviviq is effective for the treatment of insomnia, and the drug is clinically proven to reduce time-to-sleep, increase overall sleep time, and improve daytime wakefulness scores.

Quviviq does cause side effects in some patients including headache and cold symptoms, but the drug does not appear to cause severe or life-threatening side effects.

After reviewing comparative studies between Ambien and Quviviq, it appears that Ambien may be slightly more effective and Quviviq may have a slightly more favorable side effect profile.

There is not a generic alternative for Quviviq currently available on the market, so patients should speak with their health insurance provider to determine the cost of this drug, which will vary based on insurance coverage.

Some medical research suggests that use of prescription sleep medications is associated with negative health outcomes. This may be an association not a causation (because people with insomnia are less healthy in general than people without). It may be worthwhile for patients with mild insomnia to speak with their doctor about lifestyle changes or natural, OTC treatments prior to considering prescription sleep drugs.




Illuminate Labs is a proud member of

Liquid error: Could not find asset snippets/search-bar.liquid