Medicube is a Korean skincare brand that has gained global popularity, largely due to viral TikTok reviews of its exfoliating toner pads. The brand describes itself as focused on clinical skincare, and its Zero Pore Pad is marketed to reduce the appearance of enlarged pores, control excess sebum, and smooth skin texture.
But does the Medicube Zero Pore Pad contain research-backed ingredients for pore care? Does it contain any unhealthy ingredients? And is it better or worse than popular K-beauty brands like Depology and Incellderm?
In this article we'll answer all of these questions and more, as we analyze the ingredients in the Medicube Zero Pore Pad to give our take on whether or not it's likely to be effective, and whether or not it's healthy.
We'll also share our concerns about some of the clinical claims on Medicube's website, and compare the brand to other popular K-beauty brands to pick our winners and losers.
Key takeaways:
- Contains two clinically supported exfoliating actives
- Includes fragrance oils we consider a health concern
- We do not currently recommend the Medicube Zero Pore Pad
Ingredient Analysis
The ingredients in the Medicube Zero Pore Pad are shown below:

image source: https://medicube.us/products/zero-pore-pad-1
Lactic acid is an alpha-hydroxy acid (AHA) that is clinically shown to improve skin texture and reduce the appearance of photodamaged skin in a double-blind trial published in the Archives of Dermatology journal. The brand discloses a concentration of 4.5% in this formulation.
Salicylic acid is an oil-soluble beta-hydroxy acid (BHA) that penetrates sebum-filled pores to dissolve keratin plugs.
It was shown to produce significant improvements in pore visibility and oiliness control in a trial published in the Journal of Cosmetic Dermatology.
Willow bark extract is a natural source of salicin, which is clinically shown to reduce pore size.
Centella asiatica extract is included as a soothing active.
It is clinically shown to reduce skin irritation markers and improve barrier function, which is a meaningful counterbalance to the exfoliating actives in this formula.
Sodium hyaluronate is clinically shown to reduce the appearance of wrinkles and improve skin hydration, as we documented in our Luminesce Cellular Rejuvenation Serum review article.
There are ingredients in this formulation that we consider potentially unhealthy.
Lemon peel, bergamot, eucalyptus, rosemary, and lavender are fragrance oils.
Fragrance oils may irritate skin already sensitized by chemical exfoliants.
Betaine salicylate is included alongside salicylic acid and willow bark extract, creating a triple salicylate load.
Overall, we consider Medicube Zero Pore Pad likely to be effective for chemical exfoliation and pore care.
However, we do not currently recommend it due to the inclusion of multiple fragrance oils in a product designed for regular use on sensitized skin.
Questionable Clinical Claims
As shown below, Medicube claims the Zero Pore Pad achieves a 47.1% reduction in sebum, and an 87.3% decrease in pore waste, based on clinical testing:

image source: https://medicube.us/products/zero-pore-pad-1
We cannot identify any peer-reviewed clinical trial published in an independent journal to substantiate these specific figures.
Medicube states that its products are dermatologist-tested, but this often refers to irritation tolerance testing, rather than randomized efficacy trials measuring outcomes like pore size reduction.
We urge Medicube to publish the methodology and results of these studies in a peer-reviewed journal so that researchers and consumers can evaluate these claims independently.
Medicube Zero Pore Pad vs. Popular K-Beauty Brands
Here's how the Medicube Zero Pore Pad compares to other popular Korean skincare brands in terms of formulation quality, in our opinion:
Depology
Depology is one of the highest-quality K-beauty brands we have reviewed. Both products we analyzed contained research-backed actives including sodium hyaluronate, which is clinically shown to reduce signs of skin aging, and were entirely free of fragrance ingredients we consider unhealthy.
We consider Depology to have a cleaner formulation than the Medicube Zero Pore Pad.
Winner: Depology
Incellderm
Incellderm is a luxury K-beauty brand manufactured by RIMAN. As we documented in our Incellderm review article, both products we analyzed contained a wide range of research-backed actives and no ingredients we consider unhealthy — unlike the Medicube Zero Pore Pad, which contains several fragrance oils we do not recommend for use on sensitive or post-exfoliation skin.
We consider Incellderm to have a cleaner formulation than the Medicube Zero Pore Pad.
Winner: Incellderm
Sulwhasoo
Sulwhasoo is a premium Korean skincare brand known for its use of ginseng. We consider it an above-average brand from an efficacy perspective, but we cannot currently recommend its best-selling product due to the inclusion of multiple fragrance ingredients — the same concern we have with Medicube.
We consider both brands comparable on this point, though Medicube benefits from more transparent active ingredient concentration disclosures.
Winner: Tie
Medicube Zero Pore Pad Pros and Cons
Pros:
- Contains clinically supported AHA and BHA exfoliating actives
- Active ingredient concentrations are disclosed and within clinical reference ranges
- Centella asiatica provides research-backed soothing support
- Sodium hyaluronate helps counteract dryness from exfoliating actives
Cons:
- Contains multiple fragrance-derived essential oils in an exfoliating formula
- We cannot identify peer-reviewed clinical trials supporting the brand's efficacy claims
- Triple salicylate load may be excessive for sensitive skin