EnhanceRx is a male enhancement supplement that’s primarily sold online. The brand claims their product can cause “Stronger and Healthier Erections” and “Improved Sexual Drive” amongst other claimed benefits.
But does EnhanceRx contain ingredients proven to enhance erection quality? Does it have any unhealthy ingredients? Will EnhanceRx cause side effects? And why do we take issue with some of the brand's marketing claims?
In this article we’ll answer all of these questions and more, as we analyze the ingredients in EnhanceRx to give our take on whether or not the supplement is likely to be effective for male enhancement, and whether or not it's healthy.
We’ll also discuss the risk of side effects, share our concerns about some of the claims made by the manufacturer, and compare EnhanceRx to other popular male enhancement supplements like horny goat weed to pick our winners (and losers).
Key takeaways:
- No active ingredients we consider effectively dosed
- Questionable health claims on brand's website
- We do not currently recommend EnhanceRx
Ingredient Analysis
The ingredients in EnhanceRx are shown below:

image source: https://enhancerx.com/
Niacin is a B-vitamin and we can’t find any clinical evidence it improves sexual function in men.
Zinc was shown to improve testosterone (T) status in men with low testosterone in a medical review published in the Aging Male journal, but the treatment dose was 50 milligrams (mg), while only 15 mg of zinc is contained in each dose of EnhanceRx.
The remaining active ingredients are mostly herbs, and are contained in a proprietary blend totalling 515 mg, or 47 mg per ingredient.
Some of these botanical ingredients have research backing for male health and sexual function, but we can’t find any evidence they’re effective at such a low average ingredient dose.
Here are a few examples:
Tribulus terrestris was shown in a 2017 clinical trial to improve sexual function in men with erectile dysfunction (ED).
However, the format used in the above-linked study was an extract (which is more potent than the raw plant material in EnhanceRx), and the daily dose was over 1,000 mg (which is more than 20x the average ingredient dose in EnhanceRx’s prop blend).
Korean red ginseng is an effective natural erectile dysfunction (ED) treatment according to a meta-study published in the British Journal of Clinical Pharmacology.
However, the lowest dose used in any of the analyzed trials is more than 10x the average ingredient dose in EnhanceRx’s blend.
The sole inactive ingredient in this formulation (gelatin) should be safe and non-toxic.
Overall, we consider EnhanceRx potentially effective for improving libido because it contains some research-backed active ingredients.
We do not currently recommend EnhanceRx because we're unable to identify any active ingredients we consider effectively-dosed for improving erection quality.
Questionable Health Claims
There are a number of questionable health claims on the EnhanceRx website.
The brand claims that their supplement has a 97% success rate:

image source: https://enhancerx.com/
There is no definition for how “success” is achieved, and there is no citation for this claim.
We can’t find any clinical trials on EnhanceRx, so we don’t understand how the brand is making such a specific claim of efficacy.
EnhanceRx also suggests that their supplement improves testosterone levels in men in the graphic below:

image source: https://enhancerx.com/
Again, we don’t understand how EnhanceRx is making this claim if their supplement hasn’t been clinically shown to improve T levels.
We recommend that consumers be extremely cautious when considering male enhancement brands that make unproven health claims.
Does EnhanceRx Cause Side Effects?
It’s challenging to assess the risk of side effects for supplements that have not been clinically tested.
However, we can make an educated guess based on the ingredients.
We do not consider EnhanceRx likely to cause side effects in otherwise healthy adults.
The supplement is mostly composed of well-studied herbs and vitamins.
None of the active ingredients are included at a high enough dose to give us concern.
Maca is the only ingredient that we identify as a potential cause of mild side effects.
As we discussed in our Semenax review article, raw maca is indigestible, much like raw potato starch, so it may cause digestive upset.
We would recommend supplements containing the gelatinized form of maca (which is digestible) over supplements containing raw maca.
There is no mention of side effect risks for this supplement on the brand's product page at the time of updating this article.
EnhanceRx vs. Popular ED Supps
Here's how EnhanceRx compares to other popular erection quality supplements in terms of formulation quality, in our opinion:
VigorNow
VigorNow is a male enhancement supplement, formulated from herbs, that the brand claims can increase penis size and enhance sexual function.
One of the formulations sold under the "VigorNow" trade name contains tongkat ali, which is clinically shown to improve symptoms of ED.
However, it's unclear if there is an official manufacturer of this supplement, which is a consumer safety risk.
We give EnhanceRx the (slight) advantage from a safety perspective, because at least it's sold by one specific manufacturer with one specific ingredient list.
Winner: EnhanceRx
King Maker
King Maker Supplement contains one inactive ingredient we consider to be unhealthy.
EnhanceRx has the advantage from a health perspective.
Winner: EnhanceRx
Horny Goat Weed
This popular herb has lacking human efficacy data, but we find the data on this compound to be more convincing than EnhanceRx's proprietary blend from a potential efficacy standpoint.
Winner: Horny Goat Weed
Our Clean Men's Health Picks

Illuminate Labs Panax Ginseng Extract is our top erection quality pick.
Panax ginseng was shown in a clinical trial published in The Journal of Urology to increase erectile function scores "significantly" compared to participants taking placebo pills.
MBG Vitamin D3 Potency+ is our top testosterone support pick.
Vitamin D3 supplementation has been clinically shown to support healthy testosterone levels.
Both of the products recommended in this section are free of ingredients that we consider unhealthy.
These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.
EnhanceRx Pros and Cons
Pros:
- Safe active ingredients
- May improve sex drive
- Safe inactive ingredient
- Healthier than some competitors
Cons:
- Doesn’t appear to be clinically tested
- Relatively low doses in prop blend
- We do not believe this supplement is likely to be effective
- Brand makes questionable health claims
- Contains raw maca