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{"id":556896845897,"title":"ProstaGenix Review: A Pill to Reduce Prostate Size?","created_at":"2022-08-28T19:23:29-04:00","body_html":"\u003cscript type=\"application\/ld+json\"\u003e\/\/ \u003c![CDATA[\n{\n \"@context\": \"https:\/\/schema.org\",\n \"@type\": \"Article\",\n \"headline\": \"ProstaGenix Review: A Pill to Reduce Prostate Size?\",\n \"keywords\": \"prostagenix, prostagenix review, prostagenix reviews, prostagenix ingredients, prostagenix side effects, prostagenix walmart, prostagenix amazon, prostagenix price\",\n \"description\": \"Our MD and research team review the ingredients in ProstaGenix based on medical studies to give our take on whether the supplement is likely to be safe and effective. We highlight some health claims made by the brand that we find questionable.\",\n \"url\": \"https:\/\/illuminatelabs.org\/blogs\/health\/prostagenix-review\",\n\"author\": {\n \"@type\": \"Person\",\n \"name\": \"Calloway Cook\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/calloway-cook\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/calloway-cook\/\",\n \"jobTitle\": \"President\",\n \"knowsAbout\": \"entrepreneurship, dietary supplements, herbal supplements, eCommerce, medical research\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": \"S.I. Newhouse School of Public Communications at Syracuse University\"\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"creator\": {\n \"@type\": \"Person\",\n \"name\": \"Calloway Cook\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/calloway-cook\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/calloway-cook\/\",\n \"jobTitle\": \"President\",\n \"knowsAbout\": \"entrepreneurship, dietary supplements, herbal supplements, eCommerce, medical research\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": \"S.I. Newhouse School of Public Communications at Syracuse University\"\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n},\n\"editor\": {\n \"@type\": \"Person\",\n \"name\": \"Auren Weinberg\",\n \"honorificSuffix\": \"M.D.\",\n \"url\": \"https:\/\/illuminatelabs.org\/pages\/auren-weinberg\",\n \"sameAs\": \"https:\/\/www.linkedin.com\/in\/aurenweinberg\/\",\n \"jobTitle\": \"Medical Reviewer\",\n \"knowsAbout\": \"pharmaceutical medication, medicine, OTC drugs, medical research, clinical trials, generic drugs, branded drugs, dietary supplements, chemistry, health, wellness, healthcare\",\n \"alumniOf\": {\n \"@type\": \"EducationalOrganization\",\n \"name\": [\n \"Haverford College\",\n \"University of Rochester School of Medicine and Dentistry\",\n \"Fox School of Business at Temple University\"\n ]\n },\n \"memberOf\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n }\n },\n\"image\": {\n\"@type\": \"ImageObject\",\n\"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Prostagenix_Thumbnail.png?v=1661729610\",\n\"width\": \"3797\",\n\"height\": \"3797\"\n},\n\"citation\": [\n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8407049\/\", \n\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7098410\/\",\n\"https:\/\/www.cbc.ca\/news\/canada\/british-columbia\/wellness-milkshakes-chronic-vitamin-overdose-1.6363562\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18481426\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25620586\/\",\n\"https:\/\/www.consumerlab.com\/reviews\/prostate-supplements-beta-sitosterol-phytosterols-saw-palmetto\/sawpalmetto\/\",\n\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=%22prostagenix%22\",\n\"https:\/\/www.fakespot.com\/product\/prostagenix-multiphase-prostate-support-90-caps\"\n],\n\"mentions\": [{\n \"@type\": \"Thing\",\n \"name\": \"BPH\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"beta-sitosterol\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"ConsumerLab\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"Amazon\"\n },\n {\n \"@type\": \"Thing\",\n \"name\": \"FakeSpot\"\n }\n],\n\"datePublished\": \"2022-08-28\",\n\"copyrightHolder\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\"\n},\n\"publisher\": {\n \"@type\": \"Organization\",\n \"name\": \"Illuminate Labs\",\n \"url\": \"https:\/\/illuminatelabs.org\/\",\n \"description\": \"Illuminate Labs is the most transparent supplement company in the U.S., and is a leading publisher of research-based health information.\",\n \"knowsAbout\": \"supplements, science, nutrition, exercise, health, medication, pharmaceutical, wellness, diet, weight loss, medical research\",\n \"publishingPrinciples\": \"https:\/\/illuminatelabs.org\/pages\/editorial-guidelines\",\n \"logo\": {\n \"@type\": \"ImageObject\",\n \"url\": \"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/il_Logo.png?v=1646282089\", \n \"width\": 500,\n \"height\": 500\n},\n \"foundingDate\": \"2019-01-30\",\n \"sameAs\": [\n \"https:\/\/www.instagram.com\/illuminatelabs\",\n \"https:\/\/twitter.com\/illuminatelabs\",\n \"https:\/\/www.linkedin.com\/company\/illuminate-labs-supplements\",\n \"https:\/\/www.youtube.com\/channel\/UCpgSJAsIPb-fZ25djtTxBEA\"\n ]\n }\n}\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003cp\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Prostagenix_Review_Article_Header_Image_Optimized.png?v=1661729024\" alt=\"\"\u003e\u003c\/span\u003e\u003c\/i\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eDisclaimer: None of the information in this article constitutes medical advice, and is just the opinion of the writer(s) and published for informational purposes only. We recommend that patients follow their doctor’s guidance in regard to prostate health.\u003c\/span\u003e\u003c\/i\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cspan class=\"dc\"\u003eP\u003c\/span\u003erostaGenix is a dietary supplement used for prostate health. The brand claims their supplement can shrink an enlarged prostate, which they state will improve urinary flow, improve sleep patterns and reduce urinary urgency (the need to urinate frequently).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn this article we’ll review the ingredients in ProstaGenix based on published medical studies and give our determination on whether this supplement is likely to be effective for treating prostate enlargement. We’ll highlight some issues we have with the health claims made by this brand.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eIngredient Review\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/Prostagenix_Ingredients_Optimized.png?v=1661729436\" alt=\"ProstaGenix ingredients\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eP\u003c\/span\u003e\u003cspan style=\"font-weight: 400;\"\u003erostaGenix contains a number of active ingredients, but in their marketing they often reference the “sterol content” of their supplement. \u003c\/span\u003e\u003cb\u003eBeta-sitosterol\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e is an ingredient which has been studied in published medical trials for its effectiveness in reducing prostate size.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8407049\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical review\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in 1999 analyzed results from four clinical trials on beta-sitosterol supplementation and benign prostatic hyperplasia (BPH), which is the medical term for an enlarged prostate.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe researchers found that beta-sitosterol did not reduce prostate size. That same study described a 65 milligram (mg) dosage of beta-sitosterol as “high-dosage.” ProstaGenix contains over 800 mg beta-sitosterol, which is concerning to us given that we have not come across much human testing data establishing the safety of such a high dose of this compound.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe located a \u003c\/span\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7098410\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical case report\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e published in the \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eCureus\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e journal which documented a patient that developed pancreatitis as a result of beta-sitosterol supplementation. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe recommend avoiding this ingredient entirely.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOutside of the sterols, the majority of ProstaGenix ingredients are vitamins and minerals like \u003c\/span\u003e\u003cb\u003eVitamin D3\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e and \u003c\/span\u003e\u003cb\u003eselenium\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe have not come across any medical research suggesting that the vitamin and mineral blend used in ProstaGenix improves BPH or reduces prostate size.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe Canadian Broadcasting Corporation (CBC) \u003c\/span\u003e\u003ca href=\"https:\/\/www.cbc.ca\/news\/canada\/british-columbia\/wellness-milkshakes-chronic-vitamin-overdose-1.6363562\"\u003e\u003cspan style=\"font-weight: 400;\"\u003edocumented\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e how in 2022 a supplement company had to recall several products due to toxicity caused by the vitamins they added. We recommend that patients get a blood test and speak with their doctor if they believe they have vitamin deficiencies. We do not recommend taking vitamins in a non-targeted manner, or without documented vitamin deficiencies.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eProstaGenix contains a second blend called the “Polyphenol Synergistic Blend” which contains \u003c\/span\u003e\u003cb\u003egrape seed extract\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e, \u003c\/span\u003e\u003cb\u003epomegranate extract\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e and \u003c\/span\u003e\u003cb\u003equercetin\u003c\/b\u003e\u003cspan style=\"font-weight: 400;\"\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWhile there is a \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18481426\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003emedical trial\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e suggesting that grape seed extract may be effective at inhibiting prostate cancer growth, we cannot identify any trials suggesting that grape seed extract is effective for BPH or reducing prostate size.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOne \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25620586\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eanimal study\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e found pomegranate extract to be effective for BPH. However, the effective dose was vastly higher than that in ProstaGenix. The effective dose was 100 milligrams per kilogram (mg\/kg), which equates to a dose of 9,000 mg for a 90 kg man. The entire “Polyphenol Synergistic Blend” totals 300 mg, which means that the effective dose from this animal study was found to be 30x higher than the entire ProstaGenix blend dose.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe have not been able to locate any medical research suggesting that quercetin is effective for BPH.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eOverall we would not recommend this product as we cannot identify any active ingredients we would consider effective at the given dose for reducing prostate size. We are concerned with the beta-sitosterol dosage in this supplement, and we recommend avoiding any supplements containing beta-sitosterol doses this high until more medical research emerges elucidating the safe and effective dosing range of this ingredient.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIt also concerns us that there is no inactive ingredients list published on ProstaGenix’s Supplement Facts label on their website. Perhaps the supplement has no inactive ingredients, but typically it’s impossible to formulate a capsule supplement without at least one ingredient for the capsule shell.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eMany of our reviews on Illuminate Health highlight questionable inactive ingredients like artificial dye or added sugar, and manufacturers are required to publish both active ingredients and inactive ingredients on their Supplement Facts label. We urge ProstaGenix to share their inactive ingredients if this supplement does contain inactive ingredients.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cstrong\u003eQuestionable Marketing Claims\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/ProstaGenix_Questionable_Marketing_Claims_Optimized.png?v=1661729391\" alt=\"ProstaGenix questionable marketing claim 1\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eProstaGenix claims on their website that they “won the prestigious ConsumerLab.com Prostate Competition.” This is a mischaracterization.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eConsumerLab is an independent testing laboratory that tests supplements for label accuracy and purity. They do not host “competitions” with “winners.” They simply test dietary supplements based on what the supplement claims to contain.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn the case of ProstaGenix, ConsumerLab tested the supplement and found that it contained as many phytosterols as advertised. Here is the \u003c\/span\u003e\u003ca href=\"https:\/\/www.consumerlab.com\/reviews\/prostate-supplements-beta-sitosterol-phytosterols-saw-palmetto\/sawpalmetto\/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003epage on their site\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e with the testing data.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe strongly disagree with the marketing claims made by ProstaGenix in regard to these ConsumerLab test results, and we find them to be unethical.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/ProstaGenix_Questionable_Marketing_Claims_2_Optimized.png?v=1661729412\" alt=\"ProstaGenix questionable marketing claim 2\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eProstaGenix also has a graphic with some prestigious medical institutions on their website, shown above, including Yale University School of Medicine and Cedars-Sinai. This implies that their supplement has been endorsed or tested by these institutions, which has not been the case.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThere are zero results for “ProstaGenix” \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=%22prostagenix%22\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ein PubMed\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e, which is one of the largest free medical databases in the U.S. To our knowledge, there have been no medical trials published in scientific journals testing ProstaGenix, and there is no affiliation between ProstaGenix and the medical institutions whose logos they include on their website.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eA doctor at Cedars-Sinai named Dr. Dudley Danoff recommends ProstaGenix, according to their website, but that doesn't mean that the institution itself recommends it.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe disagree with this type of implied marketing, and we would recommend that ProstaGenix only use logos of medical institutions that have actually recommended their product (which to our knowledge is none).\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eQuestionable Health Claims\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/ProstaGenix_Questionable_Health_Claims_480x480.png?v=1661729346\" alt=\"ProstaGenix questionable health claim 1\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThere are a number of health claims made on the official ProstaGenix website that we disagree with or find confusing.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe brand claims that their product will stop the need to urinate at night, improve sleep quality and allow users to “wake up with energy” and improve urinary flow, eliminating “dribbles or stops and starts.”\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eNone of these medical claims listed above are cited, as seen in the image. We disagree with the practice of making uncited health claims, and we recommend that consumers avoid supplement companies making bold and uncited health claims.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0047\/1524\/9737\/files\/ProstaGenix_Questionable_Health_Claims_2_Optimized.png?v=1661729365\" alt=\"ProstaGenix Questionable Health Claim 2\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eElsewhere on the site, ProstaGenix suggests that the beta-sitosterol in their supplements is more effective than the competition because it comes from “Skinny Pine Trees” from a region in France. At the time of writing this article, there are zero medical citations in this entire section.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe have not come across any medical research suggesting that beta-sitosterol from “Skinny Pine Trees” is more effective than beta-sitosterol sourced elsewhere.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eDoes ProstaGenix Cause Side Effects?\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eGiven that ProstaGenix is comprised primarily of botanical ingredients at relatively low doses, we don’t believe it’s likely to cause side effects.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe one ingredient we believe may cause side effects is beta-sitosterol, given its relatively high dose. The case report and associated medical review that we linked to earlier in the section about a patient experiencing pancreatitis from this ingredient also documented other side effects from its supplementation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe \u003c\/span\u003e\u003ci\u003e\u003cspan style=\"font-weight: 400;\"\u003eCureus\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-weight: 400;\"\u003e review stated that gastrointestinal side effects like abdominal pain, bloating, nausea and constipation are the most common side effects of beta-sitosterol supplementation, but only occur in around 1.6% of patients. Impotence (inability to maintain erection) was also reported to occur in 0.5% of patients.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eProstaGenix Real User Reviews\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eProstaGenix has been reviewed over 5,000 times on Amazon at the time of writing this article. We consider Amazon reviews to be a more objective source of information than reviews on a manufacturer’s website. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe average rating for ProstaGenix at the time of writing this article is 3.9\/5, which is relatively unimpressive. The “Adjusted Rating” \u003c\/span\u003e\u003ca href=\"https:\/\/www.fakespot.com\/product\/prostagenix-multiphase-prostate-support-90-caps\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eon FakeSpot\u003c\/span\u003e\u003c\/a\u003e\u003cspan style=\"font-weight: 400;\"\u003e is 2\/5. FakeSpot is a software tool that detects potentially fraudulent Amazon reviews and issues ratings removing those reviews from the pool.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe top positive review of ProstaGenix from a verified purchaser is written by a user named “John Prentice” who claims the supplement has reduced his prostate pain:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e“This product works and it started working in three days. I was suffering for 5 months and almost pain free in 6 days. I expect by the end of the week I will be able to mow my lawn again.”\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe top negative review from a verified purchaser comes from a user named “John Yanyshyn” who claims the product was less effective than another prostate supplement:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e“had seen thousands of excellent reviews of Prosta Genix, so I decided to try a bottle. I switched products when the the Super Beta Prostate ran out and within a week of switching, my symptoms returned so I re-ordered the Super Beta Prostate.”\u003c\/b\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cb\u003eProstaGenix Price\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe price of ProstaGenix varies based on the marketplace. Here are the updated prices at the time of writing this article:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAmazon: \u003c\/span\u003e\u003cb\u003e$44.08\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWalmart: $44.95\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eManufacturer website: $49.95\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eGiven that shipping is also free on Amazon depending on plan, it seems like Amazon is the best retailer to purchase ProstaGenix from (though we don’t recommend purchasing ProstaGenix at all).\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cstrong\u003eConclusion\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eWe do not recommend ProstaGenix and we do not believe this supplement is likely to reduce prostate size based on the ingredients it contains. The supplement may reduce some symptoms of BPH, given that some of its ingredients have been studied for prostate effects, but overall we are not impressed by the formulation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eIn our opinion there is not much convincing medical research on dietary supplements for enhancing prostate function or reducing prostate size. We would recommend that patients experiencing discomforting symptoms due to prostate issues speak with their doctor about treatment options.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eProstaGenix makes a number of health claims on their website that we disagree with, and engages in some marketing practices we find unethical. We recommend that consumers avoid this brand entirely.\u003c\/span\u003e\u003c\/p\u003e","blog_id":49281925193,"author":"Calloway Cook","user_id":26601750601,"published_at":"2022-08-28T19:37:10-04:00","updated_at":"2022-08-29T23:10:47-04:00","summary_html":"We review the ingredients in ProstaGenix based on medical studies to give our take on whether the supplement is likely to be safe and effective. We highlight some health claims made by the brand that we find questionable.","template_suffix":"","handle":"prostagenix-review","tags":"_related:men's-health"}

ProstaGenix Review: A Pill to Reduce Prostate Size?

ProstaGenix Review: A Pill to Reduce Prostate Size?


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Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.


Read our Editorial Guidelines to learn more about what makes our site the premier resource for online health information.

Disclaimer: None of the information in this article constitutes medical advice, and is just the opinion of the writer(s) and published for informational purposes only. We recommend that patients follow their doctor’s guidance in regard to prostate health.

ProstaGenix is a dietary supplement used for prostate health. The brand claims their supplement can shrink an enlarged prostate, which they state will improve urinary flow, improve sleep patterns and reduce urinary urgency (the need to urinate frequently).

In this article we’ll review the ingredients in ProstaGenix based on published medical studies and give our determination on whether this supplement is likely to be effective for treating prostate enlargement. We’ll highlight some issues we have with the health claims made by this brand.

Ingredient Review

ProstaGenix ingredients

ProstaGenix contains a number of active ingredients, but in their marketing they often reference the “sterol content” of their supplement. Beta-sitosterol is an ingredient which has been studied in published medical trials for its effectiveness in reducing prostate size.

A medical review published in 1999 analyzed results from four clinical trials on beta-sitosterol supplementation and benign prostatic hyperplasia (BPH), which is the medical term for an enlarged prostate.

The researchers found that beta-sitosterol did not reduce prostate size. That same study described a 65 milligram (mg) dosage of beta-sitosterol as “high-dosage.” ProstaGenix contains over 800 mg beta-sitosterol, which is concerning to us given that we have not come across much human testing data establishing the safety of such a high dose of this compound.

We located a medical case report published in the Cureus journal which documented a patient that developed pancreatitis as a result of beta-sitosterol supplementation. 

We recommend avoiding this ingredient entirely.

Outside of the sterols, the majority of ProstaGenix ingredients are vitamins and minerals like Vitamin D3 and selenium.

We have not come across any medical research suggesting that the vitamin and mineral blend used in ProstaGenix improves BPH or reduces prostate size.

The Canadian Broadcasting Corporation (CBC) documented how in 2022 a supplement company had to recall several products due to toxicity caused by the vitamins they added. We recommend that patients get a blood test and speak with their doctor if they believe they have vitamin deficiencies. We do not recommend taking vitamins in a non-targeted manner, or without documented vitamin deficiencies.

ProstaGenix contains a second blend called the “Polyphenol Synergistic Blend” which contains grape seed extract, pomegranate extract and quercetin.

While there is a medical trial suggesting that grape seed extract may be effective at inhibiting prostate cancer growth, we cannot identify any trials suggesting that grape seed extract is effective for BPH or reducing prostate size.

One animal study found pomegranate extract to be effective for BPH. However, the effective dose was vastly higher than that in ProstaGenix. The effective dose was 100 milligrams per kilogram (mg/kg), which equates to a dose of 9,000 mg for a 90 kg man. The entire “Polyphenol Synergistic Blend” totals 300 mg, which means that the effective dose from this animal study was found to be 30x higher than the entire ProstaGenix blend dose.

We have not been able to locate any medical research suggesting that quercetin is effective for BPH.

Overall we would not recommend this product as we cannot identify any active ingredients we would consider effective at the given dose for reducing prostate size. We are concerned with the beta-sitosterol dosage in this supplement, and we recommend avoiding any supplements containing beta-sitosterol doses this high until more medical research emerges elucidating the safe and effective dosing range of this ingredient.

It also concerns us that there is no inactive ingredients list published on ProstaGenix’s Supplement Facts label on their website. Perhaps the supplement has no inactive ingredients, but typically it’s impossible to formulate a capsule supplement without at least one ingredient for the capsule shell.

Many of our reviews on Illuminate Health highlight questionable inactive ingredients like artificial dye or added sugar, and manufacturers are required to publish both active ingredients and inactive ingredients on their Supplement Facts label. We urge ProstaGenix to share their inactive ingredients if this supplement does contain inactive ingredients.

Questionable Marketing Claims

ProstaGenix questionable marketing claim 1

ProstaGenix claims on their website that they “won the prestigious ConsumerLab.com Prostate Competition.” This is a mischaracterization.

ConsumerLab is an independent testing laboratory that tests supplements for label accuracy and purity. They do not host “competitions” with “winners.” They simply test dietary supplements based on what the supplement claims to contain.

In the case of ProstaGenix, ConsumerLab tested the supplement and found that it contained as many phytosterols as advertised. Here is the page on their site with the testing data.

We strongly disagree with the marketing claims made by ProstaGenix in regard to these ConsumerLab test results, and we find them to be unethical.

ProstaGenix questionable marketing claim 2

ProstaGenix also has a graphic with some prestigious medical institutions on their website, shown above, including Yale University School of Medicine and Cedars-Sinai. This implies that their supplement has been endorsed or tested by these institutions, which has not been the case.

There are zero results for “ProstaGenix” in PubMed, which is one of the largest free medical databases in the U.S. To our knowledge, there have been no medical trials published in scientific journals testing ProstaGenix, and there is no affiliation between ProstaGenix and the medical institutions whose logos they include on their website.

A doctor at Cedars-Sinai named Dr. Dudley Danoff recommends ProstaGenix, according to their website, but that doesn't mean that the institution itself recommends it.

We disagree with this type of implied marketing, and we would recommend that ProstaGenix only use logos of medical institutions that have actually recommended their product (which to our knowledge is none).

Questionable Health Claims

ProstaGenix questionable health claim 1

There are a number of health claims made on the official ProstaGenix website that we disagree with or find confusing.

The brand claims that their product will stop the need to urinate at night, improve sleep quality and allow users to “wake up with energy” and improve urinary flow, eliminating “dribbles or stops and starts.”

None of these medical claims listed above are cited, as seen in the image. We disagree with the practice of making uncited health claims, and we recommend that consumers avoid supplement companies making bold and uncited health claims.

ProstaGenix Questionable Health Claim 2

Elsewhere on the site, ProstaGenix suggests that the beta-sitosterol in their supplements is more effective than the competition because it comes from “Skinny Pine Trees” from a region in France. At the time of writing this article, there are zero medical citations in this entire section.

We have not come across any medical research suggesting that beta-sitosterol from “Skinny Pine Trees” is more effective than beta-sitosterol sourced elsewhere.

Does ProstaGenix Cause Side Effects?

Given that ProstaGenix is comprised primarily of botanical ingredients at relatively low doses, we don’t believe it’s likely to cause side effects.

The one ingredient we believe may cause side effects is beta-sitosterol, given its relatively high dose. The case report and associated medical review that we linked to earlier in the section about a patient experiencing pancreatitis from this ingredient also documented other side effects from its supplementation.

The Cureus review stated that gastrointestinal side effects like abdominal pain, bloating, nausea and constipation are the most common side effects of beta-sitosterol supplementation, but only occur in around 1.6% of patients. Impotence (inability to maintain erection) was also reported to occur in 0.5% of patients.

ProstaGenix Real User Reviews

ProstaGenix has been reviewed over 5,000 times on Amazon at the time of writing this article. We consider Amazon reviews to be a more objective source of information than reviews on a manufacturer’s website. 

The average rating for ProstaGenix at the time of writing this article is 3.9/5, which is relatively unimpressive. The “Adjusted Rating” on FakeSpot is 2/5. FakeSpot is a software tool that detects potentially fraudulent Amazon reviews and issues ratings removing those reviews from the pool.

The top positive review of ProstaGenix from a verified purchaser is written by a user named “John Prentice” who claims the supplement has reduced his prostate pain:

“This product works and it started working in three days. I was suffering for 5 months and almost pain free in 6 days. I expect by the end of the week I will be able to mow my lawn again.”

The top negative review from a verified purchaser comes from a user named “John Yanyshyn” who claims the product was less effective than another prostate supplement:

“had seen thousands of excellent reviews of Prosta Genix, so I decided to try a bottle. I switched products when the the Super Beta Prostate ran out and within a week of switching, my symptoms returned so I re-ordered the Super Beta Prostate.”

ProstaGenix Price

The price of ProstaGenix varies based on the marketplace. Here are the updated prices at the time of writing this article:

Amazon: $44.08

Walmart: $44.95

Manufacturer website: $49.95

Given that shipping is also free on Amazon depending on plan, it seems like Amazon is the best retailer to purchase ProstaGenix from (though we don’t recommend purchasing ProstaGenix at all).

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Conclusion

We do not recommend ProstaGenix and we do not believe this supplement is likely to reduce prostate size based on the ingredients it contains. The supplement may reduce some symptoms of BPH, given that some of its ingredients have been studied for prostate effects, but overall we are not impressed by the formulation.

In our opinion there is not much convincing medical research on dietary supplements for enhancing prostate function or reducing prostate size. We would recommend that patients experiencing discomforting symptoms due to prostate issues speak with their doctor about treatment options.

ProstaGenix makes a number of health claims on their website that we disagree with, and engages in some marketing practices we find unethical. We recommend that consumers avoid this brand entirely.





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